Recently Published Research

Classifying Polycyclic Aromatic Hydrocarbons by Carcinogenic Potency Using In Vitro Biosignatures [Abstract Classifying Polycyclic Aromatic Hydrocarbons by Carcinogenic Potency Using In Vitro Biosignatures] [Synopsis Classifying Polycyclic Aromatic Hydrocarbons by Carcinogenic Potency Using In Vitro Biosignatures] Chang Y, Huynh CTT, Bastin KM, Rivera BN, Siddens LK, Tilton SC. December 2020

Fetal and Early Postnatal Lead Exposure Measured in Teeth Associates With Infant Gut Microbiota [Abstract Fetal and Early Postnatal Lead Exposure Measured in Teeth Associates With Infant Gut Microbiota] [Synopsis Fetal and Early Postnatal Lead Exposure Measured in Teeth Associates With Infant Gut Microbiota] Sitarik AR, Arora M, Austin C, Bielak LF, Eggers S, Johnson CC, Lynch SV, Kyun Park S, Hank Wu KH, Yong GJM, Cassidy-Bushrow AE. November 2020

Comparison of Phytochemical Composition of Ginkgo Biloba Extracts Using a Combination of Non-targeted and Targeted Analytical Approaches [Abstract Comparison of Phytochemical Composition of Ginkgo Biloba Extracts Using a Combination of Non-targeted and Targeted Analytical Approaches] [Synopsis Comparison of Phytochemical Composition of Ginkgo Biloba Extracts Using a Combination of Non-targeted and Targeted Analytical Approaches] Collins BJ, Kerns SP, Aillon K, Mueller G, Rider CV, DeRose EF, London RE, Harnly JM, Waidyanatha S. October 2020

Harnessing In Silico, In Vitro, and In Vivo Data to Understand the Toxicity Landscape of Polycyclic Aromatic Compounds (PACs) [Abstract Harnessing In Silico, In Vitro, and In Vivo Data to Understand the Toxicity Landscape of Polycyclic Aromatic Compounds (PACs)] [Synopsis Harnessing In Silico, In Vitro, and In Vivo Data to Understand the Toxicity Landscape of Polycyclic Aromatic Compounds (PACs)] Hsieh JH, Sedykh A, Mutlu E, Germolec DR, Auerbach SS, Rider CV. October 2020

High-fat Food Biases Hypothalamic and Mesolimbic Expression of Consummatory Drives [Abstract High-fat Food Biases Hypothalamic and Mesolimbic Expression of Consummatory Drives] [Synopsis High-fat Food Biases Hypothalamic and Mesolimbic Expression of Consummatory Drives] Mazzone CM, Liang-Guallpa J, Li C, Wolcott NS, Boone MH, Southern M, Kobzar NP, Salgado IA, Reddy DM, Sun F, Zhang Y, Li Y, Cui G, Krashes MJ. October 2020

Arsenic in U.S. Correctional Facility Drinking Water, 2006-2011 [Abstract Arsenic in U.S. Correctional Facility Drinking Water, 2006-2011] [Synopsis Arsenic in U.S. Correctional Facility Drinking Water, 2006-2011] Nigra AE, Navas-Acien A. September 2020

Blinded RT-QuIC Analysis of Alpha-synuclein Biomarker in Skin Tissue From Parkinson’s Disease Patients [Abstract Blinded RT-QuIC Analysis of Alpha-synuclein Biomarker in Skin Tissue From Parkinson’s Disease Patients] [Synopsis Blinded RT-QuIC Analysis of Alpha-synuclein Biomarker in Skin Tissue From Parkinson’s Disease Patients] Manne S, Kondru N, Jin H, Serrano GE, Anantharam V, Kanthasamy A, Adler CH, Beach TG, Kanthasamy AG. September 2020

Electronic Nicotine Delivery System Aerosol-induced Cell Death and Dysfunction in Macrophages and Lung Epithelial Cells [Abstract Electronic Nicotine Delivery System Aerosol-induced Cell Death and Dysfunction in Macrophages and Lung Epithelial Cells] [Synopsis Electronic Nicotine Delivery System Aerosol-induced Cell Death and Dysfunction in Macrophages and Lung Epithelial Cells] Serpa GL, Renton ND, Lee N, Crane MJ, Jamieson AM. September 2020

Identifying Issues and Priorities in Reporting Back Environmental Health Data [Abstract Identifying Issues and Priorities in Reporting Back Environmental Health Data] [Synopsis Identifying Issues and Priorities in Reporting Back Environmental Health Data] Lebow-Skelley E, Yelton S, Janssen B, Erdei E, Pearson MA. September 2020

Pregnancy Per- and Polyfluoroalkyl Substance Concentrations and Postpartum Health in Project Viva: A Prospective Cohort [Abstract Pregnancy Per- and Polyfluoroalkyl Substance Concentrations and Postpartum Health in Project Viva: A Prospective Cohort] [Synopsis Pregnancy Per- and Polyfluoroalkyl Substance Concentrations and Postpartum Health in Project Viva: A Prospective Cohort] Mitro SD, Sagiv SK, Fleisch AF, Jaacks LM, Williams PL, Rifas-Shiman SL, Calafat AM, Hivert MF, Oken E, James-Todd TM. September 2020

Single Nucleotide Resolution Analysis Reveals Pervasive, Long-Lasting DNA Methylation Changes by Developmental Exposure to a Mitochondrial Toxicant [Abstract Single Nucleotide Resolution Analysis Reveals Pervasive, Long-Lasting DNA Methylation Changes by Developmental Exposure to a Mitochondrial Toxicant] [Synopsis Single Nucleotide Resolution Analysis Reveals Pervasive, Long-Lasting DNA Methylation Changes by Developmental Exposure to a Mitochondrial Toxicant] Lozoya OA, Xu F, Grenet D, Wang T, Grimm SA, Godfrey V, Waidyanatha S, Woychik RP, Santos JH. September 2020

Structural Snapshots of Human DNA Polymerase Mu Engaged on a DNA Double-strand Break [Abstract Structural Snapshots of Human DNA Polymerase Mu Engaged on a DNA Double-strand Break] [Synopsis Structural Snapshots of Human DNA Polymerase Mu Engaged on a DNA Double-strand Break] Kaminski AM, Pryor JM, Ramsden DA, Kunkel TA, Pedersen LC, Bebenek K. September 2020

Ultrasensitive Deletion Detection Links Mitochondrial DNA Replication, Disease, and Aging [Abstract Ultrasensitive Deletion Detection Links Mitochondrial DNA Replication, Disease, and Aging] [Synopsis Ultrasensitive Deletion Detection Links Mitochondrial DNA Replication, Disease, and Aging] Lujan SA, Longley MJ, Humble MH, Lavender CA, Burkholder A, Blakely EL, Alston CL, Gorman GS, Turnbull DM, McFarland R, Taylor RW, Kunkel TA, Copeland WC. September 2020

Uterine Fibroid Incidence and Growth in an Ultrasound-based, Prospective Study of Young African Americans [Abstract Uterine Fibroid Incidence and Growth in an Ultrasound-based, Prospective Study of Young African Americans] [Synopsis Uterine Fibroid Incidence and Growth in an Ultrasound-based, Prospective Study of Young African Americans] Baird DD, Patchel SA, Saldana TM, Umbach DM, Cooper T, Wegienka G, Harmon QE. September 2020

Vitamin E is Necessary for Zebrafish Nervous System Development [Abstract Vitamin E is Necessary for Zebrafish Nervous System Development] [Synopsis Vitamin E is Necessary for Zebrafish Nervous System Development] Head B, La Du J, Tanguay RL, Kioussi C, Traber MG. September 2020

Erythrocyte Omega-3 Index, Ambient Fine Particle Exposure, and Brain Aging [Abstract Erythrocyte Omega-3 Index, Ambient Fine Particle Exposure, and Brain Aging] [Synopsis Erythrocyte Omega-3 Index, Ambient Fine Particle Exposure, and Brain Aging] Chen C, Xun P, Kaufman JD, Hayden KM, Espeland MA, Whitsel EA, Serre ML, Vizuete W, Orchard T, Harris WS, Wang X, Chui HC, Chen JC, He K. August 2020

Genetic and Functional Insights Into the Fractal Structure of the Heart [Abstract Genetic and Functional Insights Into the Fractal Structure of the Heart] [Synopsis Genetic and Functional Insights Into the Fractal Structure of the Heart] Meyer HV, Dawes TJW, Serrani M, Bai W, Tokarczuk P, Cai J, de Marvao A, Henry A, Lumbers RT, Gierten J, Thumberger T, Wittbrodt J, Ware JS, Rueckert D, Matthews PM, Prasad SK, Costantino ML, Cook SA, Birney E, O'Regan DP. August 2020

HNF4alpha Regulates Sulfur Amino Acid Metabolism and Confers Sensitivity to Methionine Restriction in Liver Cancer [Abstract HNF4alpha Regulates Sulfur Amino Acid Metabolism and Confers Sensitivity to Methionine Restriction in Liver Cancer] [Synopsis HNF4alpha Regulates Sulfur Amino Acid Metabolism and Confers Sensitivity to Methionine Restriction in Liver Cancer] [Story HNF4alpha Regulates Sulfur Amino Acid Metabolism and Confers Sensitivity to Methionine Restriction in Liver Cancer] Xu Q, Li Y, Gao X, Kang K, Williams JG, Tong L, Liu J, Ji M, Deterding LJ, Tong X, Locasale JW, Li L, Shats I, Li X. August 2020

InsP7 Is a Small-molecule Regulator of NUDT3-mediated MRNA Decapping and Processing-body Dynamics [Abstract InsP7 Is a Small-molecule Regulator of NUDT3-mediated MRNA Decapping and Processing-body Dynamics] [Synopsis InsP7 Is a Small-molecule Regulator of NUDT3-mediated MRNA Decapping and Processing-body Dynamics] Sahu S, Wang Z, Jiao X, Gu C, Jork N, Wittwer C, Li X, Hostachy S, Fiedler D, Wang H, Jessen HJ, Kiledjian M, Shears SB. August 2020

Longitudinal Profiles of Plasma Eicosanoids During Pregnancy and Size For Gestational Age at Delivery: A Nested Case-Control Study [Abstract Longitudinal Profiles of Plasma Eicosanoids During Pregnancy and Size For Gestational Age at Delivery: A Nested Case-Control Study] [Synopsis Longitudinal Profiles of Plasma Eicosanoids During Pregnancy and Size For Gestational Age at Delivery: A Nested Case-Control Study] Welch BM, Keil AP, van 't Erve TJ, Deterding LJ, Williams JG, Lih FB, Cantonwine DE, McElrath TF, Ferguson KK. August 2020

Metabolic Effects of Air Pollution Exposure and Reversibility [Abstract Metabolic Effects of Air Pollution Exposure and Reversibility] [Synopsis Metabolic Effects of Air Pollution Exposure and Reversibility] Rajagopalan S, Park B, Palanivel R, Vinayachandran V, Deiuliis JA, Gangwar RS, Das LM, Yin J, Choi Y, Al-Kindi S, Jain MK, Hansen KD, Biswal S. August 2020

Prenatal Exposure to Perfluoroalkyl Substances Associated With Increased Susceptibility to Liver Injury in Children [Abstract Prenatal Exposure to Perfluoroalkyl Substances Associated With Increased Susceptibility to Liver Injury in Children] [Synopsis Prenatal Exposure to Perfluoroalkyl Substances Associated With Increased Susceptibility to Liver Injury in Children] Stratakis N, Conti DV, Jin R, Margetaki K, Valvi D, Siskos AP, Maitre L, Garcia E, Varo N, Zhao Y, Roumeliotaki T, Vafeiadi M, Urquiza J, Fernandez-Barres S, Heude B, Basagana X, Casas M, Fossati S, Grazuleviciene R, Andrusaityte S, Uppal K, McEachan RR, Papadopoulou E, Robinson O, Haug LS, Wright J, Vos MB, Keun HC, Vrijheid M, Berhane KT, McConnell R, Chatzi L. August 2020

A National-scale Assessment of Mercury Bioaccumulation in United States National Parks Using Dragonfly Larvae As Biosentinels Through a Citizen-science Framework [Abstract A National-scale Assessment of Mercury Bioaccumulation in United States National Parks Using Dragonfly Larvae As Biosentinels Through a Citizen-science Framework] [Synopsis A National-scale Assessment of Mercury Bioaccumulation in United States National Parks Using Dragonfly Larvae As Biosentinels Through a Citizen-science Framework] Eagles-Smith CA, Willacker JJ, Nelson SJ, Flanagan Pritz CM, Krabbenhoft DP, Chen CY, Ackerman JT, Grant EHC, Pilliod DS. July 2020

Butylparaben Multigenerational Reproductive Assessment by Continuous Breeding in Hsd:Sprague Dawley SD Rats Following Dietary Exposure [Abstract Butylparaben Multigenerational Reproductive Assessment by Continuous Breeding in Hsd:Sprague Dawley SD Rats Following Dietary Exposure] [Synopsis Butylparaben Multigenerational Reproductive Assessment by Continuous Breeding in Hsd:Sprague Dawley SD Rats Following Dietary Exposure] Quiros-Alcala L, Hansel NN, McCormack M, Calafat AM, Ye X, Peng RD, Matsui EC. July 2020

Diesel Exhaust Extract Exposure Induces Neuronal Toxicity by Disrupting Autophagy [Abstract Diesel Exhaust Extract Exposure Induces Neuronal Toxicity by Disrupting Autophagy] [Synopsis Diesel Exhaust Extract Exposure Induces Neuronal Toxicity by Disrupting Autophagy] Barnhill LM, Khuansuwan S, Juarez D, Murata H, Araujo JA, Bronstein JM. July 2020

Exposure to Bisphenols and Asthma Morbidity Among Low-Income Urban Children With Asthma [Abstract Exposure to Bisphenols and Asthma Morbidity Among Low-Income Urban Children With Asthma] [Synopsis Exposure to Bisphenols and Asthma Morbidity Among Low-Income Urban Children With Asthma] Quiros-Alcala L, Hansel NN, McCormack M, Calafat AM, Ye X, Peng RD, Matsui EC. July 2020

InterPred: A Webtool to Predict Chemical Autofluorescence and Luminescence Interference [Abstract InterPred: A Webtool to Predict Chemical Autofluorescence and Luminescence Interference] [Synopsis InterPred: A Webtool to Predict Chemical Autofluorescence and Luminescence Interference] Borrel A, Mansouri K, Nolte S, Saddler T, Conway M, Schmitt C, Kleinstreuer NC. July 2020

QSAR Modeling of SARS‐CoV Mpro Inhibitors Identifies Sufugolix, Cenicriviroc, Proglumetacin, and Other Drugs as Candidates for Repurposing Against SARS‐CoV‐2 [Abstract QSAR Modeling of SARS‐CoV Mpro Inhibitors Identifies Sufugolix, Cenicriviroc, Proglumetacin, and Other Drugs as Candidates for Repurposing Against SARS‐CoV‐2] [Synopsis QSAR Modeling of SARS‐CoV Mpro Inhibitors Identifies Sufugolix, Cenicriviroc, Proglumetacin, and Other Drugs as Candidates for Repurposing Against SARS‐CoV‐2] Alves VM, Bobrowski T, Melo-Filho CC, Korn D, Auerbach S, Schmitt C, Muratov EN, Tropsha A. July 2020

The Role of Ambient Particle Radioactivity in Inflammation and Endothelial Function in an Elderly Cohort [Abstract The Role of Ambient Particle Radioactivity in Inflammation and Endothelial Function in an Elderly Cohort] [Synopsis The Role of Ambient Particle Radioactivity in Inflammation and Endothelial Function in an Elderly Cohort] Blomberg AJ, Nyhan MM, Bind MA, Vokonas P, Coull BA, Schwartz J, Koutrakis P. July 2020

Tox21BodyMap: A Webtool To Map Chemical Effects On the Human Body [Abstract Tox21BodyMap: A Webtool To Map Chemical Effects On the Human Body] [Synopsis Tox21BodyMap: A Webtool To Map Chemical Effects On the Human Body] Borrel A, Auerbach SS, Houck KA, Kleinstreuer NC. July 2020

Associations of Perfluoroalkyl Substances with Incident Natural Menopause: the Study of Women's Health Across the Nation [Abstract Associations of Perfluoroalkyl Substances with Incident Natural Menopause: the Study of Women's Health Across the Nation] [Synopsis Associations of Perfluoroalkyl Substances with Incident Natural Menopause: the Study of Women's Health Across the Nation] Ding N, Harlow SD, Randolph JF, Calafat AM, Mukherjee B, Batterman S, Gold EB, Park SK. June 2020

A Universal Gut-microbiome-derived Signature Predicts Cirrhosis [Abstract A Universal Gut-microbiome-derived Signature Predicts Cirrhosis] [Synopsis A Universal Gut-microbiome-derived Signature Predicts Cirrhosis] Oh TG, Kim SM, Caussy C, Fu T, Guo J, Bassirian S, Singh S, Madamba EV, Bettencourt R, Richards L, Raffatellu M, Dorrestein PC, Yu RT, Atkins AR, Huan T, Brenner DA, Sirlin CB, Knight R, Downes M, Evans RM, Loomba R. June 2020

Cholesterol 25-hydroxylase Promotes Efferocytosis and Resolution of Lung Inflammation [Abstract Cholesterol 25-hydroxylase Promotes Efferocytosis and Resolution of Lung Inflammation] [Synopsis Cholesterol 25-hydroxylase Promotes Efferocytosis and Resolution of Lung Inflammation] Madenspacher JH, Morrell ED, Gowdy KM, McDonald JG, Thompson BM, Muse G, Martinez J, Thomas S, Mikacenic C, Nick JA, Abraham E, Garantziotis S, Stapleton RD, Meacham JM, Thomassen MJ, Janssen WJ, Cook DN, Wurfel MM, Fessler MB. June 2020

Developmentally Programmed Tankyrase Activity Upregulates Beta-catenin and Licenses Progression of Embryonic Genome Activation [Abstract Developmentally Programmed Tankyrase Activity Upregulates Beta-catenin and Licenses Progression of Embryonic Genome Activation] [Synopsis Developmentally Programmed Tankyrase Activity Upregulates Beta-catenin and Licenses Progression of Embryonic Genome Activation] [Story Developmentally Programmed Tankyrase Activity Upregulates Beta-catenin and Licenses Progression of Embryonic Genome Activation] Gambini A, Stein P, Savy V, Grow EJ, Papas BN, Zhang Y, Kenan AC, Padilla-Banks E, Cairns BR, Williams CJ. June 2020

Dioxin-like Compound Exposures and DNA Methylation in the Anniston Community Health Survey Phase II [Abstract Dioxin-like Compound Exposures and DNA Methylation in the Anniston Community Health Survey Phase II] [Synopsis Dioxin-like Compound Exposures and DNA Methylation in the Anniston Community Health Survey Phase II] Pittman GS, Wang X, Campbell MR, Coulter SJ, Olson JR, Pavuk M, Birnbaum LS, Bell DA. June 2020

Evaluation of 5-Day In Vivo Rat Liver and Kidney with High-Throughput Transcriptomics for Estimating Benchmark Doses of Apical Outcomes [Abstract Evaluation of 5-Day In Vivo Rat Liver and Kidney with High-Throughput Transcriptomics for Estimating Benchmark Doses of Apical Outcomes] [Synopsis Evaluation of 5-Day In Vivo Rat Liver and Kidney with High-Throughput Transcriptomics for Estimating Benchmark Doses of Apical Outcomes] Gwinn WM, Auerbach SS, Parham F, Stout MD, Waidyanatha S, Mutlu E, Collins B, Paules RS, Merrick BA, Ferguson S, Ramaiahgari S, Bucher JR, Sparrow B, Toy H, Gorospe J, Machesky N, Shah RR, Balik-Meisner MR, Mav D, Phadke DP, Roberts G, DeVito MJ. June 2020

Hippocampal Interneuronal α7 nAChRs Modulate Theta Oscillations in Freely Moving Mice [Abstract Hippocampal Interneuronal α7 nAChRs Modulate Theta Oscillations in Freely Moving Mice] [Synopsis Hippocampal Interneuronal α7 nAChRs Modulate Theta Oscillations in Freely Moving Mice] Gu Z, Smith KG, Alexander GM, Guerreiro I, Dudek SM, Gutkin B, Jensen P, Yakel JL. June 2020

HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis [Abstract HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis] [Synopsis HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis] Bai G, Kermi C, Stoy H, Schiltz CJ, Bacal J, Zaino AM, Hadden MK, Eichman BF, Lopes M, Cimprich KA. June 2020

House Dust Microbiota in Relation to Adult Asthma and Atopy in a U.S. Farming Population [Abstract House Dust Microbiota in Relation to Adult Asthma and Atopy in a U.S. Farming Population] [Synopsis House Dust Microbiota in Relation to Adult Asthma and Atopy in a U.S. Farming Population] [Story House Dust Microbiota in Relation to Adult Asthma and Atopy in a U.S. Farming Population] Lee MK, Wyss AB, Carnes MU, Richards M, Parks CG, Beane Freeman LE, Thorne PS, Umbach DM, Azcarate-Peril MA, Peddada SD, London SJ. June 2020

Increasing Prevalence of Antinuclear Antibodies in the United States [Abstract Increasing Prevalence of Antinuclear Antibodies in the United States] [Synopsis Increasing Prevalence of Antinuclear Antibodies in the United States] [Story Increasing Prevalence of Antinuclear Antibodies in the United States] Dinse GE, Parks CG, Weinberg CR, Co CA, Wilkerson J, Zeldin DC, Chan EKL, Miller FW. June 2020

Reconstitution of the Human tRNA Splicing Endonuclease Complex: Insight Into the Regulation of Pre-tRNA Cleavage [Abstract Reconstitution of the Human tRNA Splicing Endonuclease Complex: Insight Into the Regulation of Pre-tRNA Cleavage] [Synopsis Reconstitution of the Human tRNA Splicing Endonuclease Complex: Insight Into the Regulation of Pre-tRNA Cleavage] Hayne CK, Schmidt CA, Haque MI, Matera AG, Stanley RE. June 2020

Ubiquitin Stimulated Reversal of Topoisomerase 2 DNA-protein Crosslinks by TDP2 [Abstract Ubiquitin Stimulated Reversal of Topoisomerase 2 DNA-protein Crosslinks by TDP2] [Synopsis Ubiquitin Stimulated Reversal of Topoisomerase 2 DNA-protein Crosslinks by TDP2] Schellenberg MJ, Appel CD, Riccio AA, Butler LR, Krahn JM, Liebermann JA, Cortes-Ledesma F, Williams RS. June 2020

Analgesic Use at Ovulation and Implantation and Human Fertility [Abstract Analgesic Use at Ovulation and Implantation and Human Fertility] [Synopsis Analgesic Use at Ovulation and Implantation and Human Fertility] Jukic AMZ, Padiyara P, Bracken MB, McConnaughey DR, Steiner AZ. May 2020

Cancer-specific Mutation of GATA3 Disrupts the Transcriptional Regulatory Network Governed by Estrogen Receptor Alpha, FOXA1 and GATA3 [Abstract Cancer-specific Mutation of GATA3 Disrupts the Transcriptional Regulatory Network Governed by Estrogen Receptor Alpha, FOXA1 and GATA3] [Synopsis Cancer-specific Mutation of GATA3 Disrupts the Transcriptional Regulatory Network Governed by Estrogen Receptor Alpha, FOXA1 and GATA3] Takaku M, Grimm SA, De Kumar B, Bennett BD, Wade PA. May 2020

Construction of a Web-Based Nanomaterial Database by Big Data Curation and Modeling Friendly Nanostructure Annotations [Abstract Construction of a Web-Based Nanomaterial Database by Big Data Curation and Modeling Friendly Nanostructure Annotations] [Synopsis Construction of a Web-Based Nanomaterial Database by Big Data Curation and Modeling Friendly Nanostructure Annotations] Yan X, Sedykh A, Wang W, Yan B, Zhu H. May 2020

Detrimental Effects of Flame Retardant, PBB153, Exposure on Sperm and Future Generations [Abstract Detrimental Effects of Flame Retardant, PBB153, Exposure on Sperm and Future Generations] [Synopsis Detrimental Effects of Flame Retardant, PBB153, Exposure on Sperm and Future Generations] Greeson KW, Fowler KL, Estave PM, Kate Thompson S, Wagner C, Clayton Edenfield R, Symosko KM, Steves AN, Marder EM, Terrell ML, Barton H, Koval M, Marcus M, Easley CA 4th. May 2020

Effects of Early Life Exposure to Traffic-Related Air Pollution on Brain Development in Juvenile Sprague-Dawley Rats [Abstract Effects of Early Life Exposure to Traffic-Related Air Pollution on Brain Development in Juvenile Sprague-Dawley Rats] [Synopsis Effects of Early Life Exposure to Traffic-Related Air Pollution on Brain Development in Juvenile Sprague-Dawley Rats] Patten KT, Gonzalez EA, Valenzuela A, Berg E, Wallis C, Garbow JR, Silverman JL, Bein KJ, Wexler AS, Lein PJ. May 2020

Epigenome Environment Interactions Accelerate Epigenomic Aging and Unlock Metabolically Restricted Epigenetic Reprogramming in Adulthood [Abstract Epigenome Environment Interactions Accelerate Epigenomic Aging and Unlock Metabolically Restricted Epigenetic Reprogramming in Adulthood] [Synopsis Epigenome Environment Interactions Accelerate Epigenomic Aging and Unlock Metabolically Restricted Epigenetic Reprogramming in Adulthood] Trevino LS, Dong J, Kaushal A, Katz TA, Jangid RK, Robertson MJ, Grimm SL, Ambati CSR, Putluri V, Cox AR, Kim KH, May TD, Gallo MR, Moore DD, Hartig SM, Foulds CE, Putluri N, Coarfa C, Walker CL. May 2020

Maternal Glyphosate Exposure Causes Autism-like Behaviors in Offspring Through Increased Expression of Soluble Epoxide Hydrolase [Abstract Maternal Glyphosate Exposure Causes Autism-like Behaviors in Offspring Through Increased Expression of Soluble Epoxide Hydrolase] [Synopsis Maternal Glyphosate Exposure Causes Autism-like Behaviors in Offspring Through Increased Expression of Soluble Epoxide Hydrolase] Pu Y, Yang J, Chang L, Qu Y, Wang S, Zhang K, Xiong Z, Zhang J, Tan Y, Wang X, Fujita Y, Ishima T, Wang D, Hwang SH, Hammock BD, Hashimoto K. May 2020

Microglial Exosomes Facilitate Alpha-synuclein Transmission in Parkinson's Disease [Abstract Microglial Exosomes Facilitate Alpha-synuclein Transmission in Parkinson's Disease] [Synopsis Microglial Exosomes Facilitate Alpha-synuclein Transmission in Parkinson's Disease] Guo M, Wang J, Zhao Y, Feng Y, Han S, Dong Q, Cui M, Tieu K. May 2020

Postnatal Effects of Gestational and Lactational Gavage Exposure to Boric Acid in the Developing Sprague Dawley Rat [Abstract Postnatal Effects of Gestational and Lactational Gavage Exposure to Boric Acid in the Developing Sprague Dawley Rat] [Synopsis Postnatal Effects of Gestational and Lactational Gavage Exposure to Boric Acid in the Developing Sprague Dawley Rat] Watson ATD, Sutherland VL, Cunny H, Miller-Pinsler L, Furr J, Hebert C, Collins B, Waidyanatha S, Smith L, Vinke T, Aillon K, Xie G, Shockley KR, McIntyre BS. May 2020

A Comprehensive Analysis of Racial Disparities in Chemical Biomarker Concentrations in United States Women, 1999-2014 [Abstract A Comprehensive Analysis of Racial Disparities in Chemical Biomarker Concentrations in United States Women, 1999-2014] [Synopsis A Comprehensive Analysis of Racial Disparities in Chemical Biomarker Concentrations in United States Women, 1999-2014] Nguyen VK, Kahana A, Heidt J, Polemi K, Kvasnicka J, Jolliet O, Colacino JA. April 2020

Association of Preeclampsia in Term Births With Neurodevelopmental Disorders in Offspring [Abstract Association of Preeclampsia in Term Births With Neurodevelopmental Disorders in Offspring] [Synopsis Association of Preeclampsia in Term Births With Neurodevelopmental Disorders in Offspring] [Story Association of Preeclampsia in Term Births With Neurodevelopmental Disorders in Offspring] Sun BZ, Moster D, Harmon QE, Wilcox AJ. April 2020

Deletion of Topoisomerase 1 in Excitatory Neurons Causes Genomic Instability and Early Onset Neurodegeneration [Abstract Deletion of Topoisomerase 1 in Excitatory Neurons Causes Genomic Instability and Early Onset Neurodegeneration] [Synopsis Deletion of Topoisomerase 1 in Excitatory Neurons Causes Genomic Instability and Early Onset Neurodegeneration] Fragola G, Mabb AM, Taylor-Blake B, Niehaus JK, Chronister WD, Mao H, Simon JM, Yuan H, Li Z, McConnell MJ, Zylka MJ. April 2020

Improved Asthma Outcomes Observed in the Vicinity of Coal Power Plant Retirement, Retrofit and Conversion to Natural Gas [Abstract Improved Asthma Outcomes Observed in the Vicinity of Coal Power Plant Retirement, Retrofit and Conversion to Natural Gas] [Synopsis Improved Asthma Outcomes Observed in the Vicinity of Coal Power Plant Retirement, Retrofit and Conversion to Natural Gas] Casey JA, Su JG, Henneman LRF, Zigler C, Neophytou AM, Catalano R, Gondalia R, Chen Y-T, Kaye L, Moyer SS, Combs V, Simrall G, Smith T, Sublett J, Barrett MA. April 2020

Unique MicroRNA Alterations in Hepatocellular Carcinomas Arising Either Spontaneously or Due to Chronic Exposure to Ginkgo Biloba Extract (GBE) in B6C3F1/N Mice [Abstract Unique MicroRNA Alterations in Hepatocellular Carcinomas Arising Either Spontaneously or Due to Chronic Exposure to Ginkgo Biloba Extract (GBE) in B6C3F1/N Mice] [Synopsis Unique MicroRNA Alterations in Hepatocellular Carcinomas Arising Either Spontaneously or Due to Chronic Exposure to Ginkgo Biloba Extract (GBE) in B6C3F1/N Mice] Yamashita H, Surapureddi S, Kovi RC, Bhusari S, Ton TV, Li J-L, Shockley K, Peddada SD, Gerrish KE, Rider CV, Hoenerhoff MJ, Sills RC, Pandiri AR. April 2020

A Strategy For Test Article Selection and Phytochemical Characterization of Echinacea purpurea Extract For Safety Testing [Abstract A Strategy For Test Article Selection and Phytochemical Characterization of Echinacea purpurea Extract For Safety Testing] [Synopsis A Strategy For Test Article Selection and Phytochemical Characterization of Echinacea purpurea Extract For Safety Testing] Waidyanatha S, Pierfelice J, Cristy T, Mutlu E, Burback B, Rider CV, Ryan K. March 2020

Bisphenol A and Bisphenol S Disruptions of the Mouse Placenta and Potential Effects on the Placenta-Brain Axis [Abstract Bisphenol A and Bisphenol S Disruptions of the Mouse Placenta and Potential Effects on the Placenta-Brain Axis] [Synopsis Bisphenol A and Bisphenol S Disruptions of the Mouse Placenta and Potential Effects on the Placenta-Brain Axis] Mao J, Jain A, Denslow ND, Nouri MZ, Chen S, Wang T, Zhu N, Koh J, Sarma SJ, Sumner BW, Lei Z, Sumner LW, Bivens NJ, Roberts RM, Tuteja G, Rosenfeld CS. March 2020

Elevated Levels of Per- and Polyfluoroalkyl Substances in Cape Fear River Striped Bass (Morone saxatilis) Are Associated with Biomarkers of Altered Immune and Liver Function [Abstract Elevated Levels of Per- and Polyfluoroalkyl Substances in Cape Fear River Striped Bass (Morone saxatilis) Are Associated with Biomarkers of Altered Immune and Liver Function] [Synopsis Elevated Levels of Per- and Polyfluoroalkyl Substances in Cape Fear River Striped Bass (Morone saxatilis) Are Associated with Biomarkers of Altered Immune and Liver Function] TC, McCord J, Guillette M, Polera ME, Rachels KT, Morgeson C, Kotlarz N, Knappe DRU, Reading BJ, Strynar N, Belcher SM. March 2020

Glucocorticoids Mobilize Macrophages By Transcriptionally Up-regulating the Exopeptidase DPP4 [Abstract Glucocorticoids Mobilize Macrophages By Transcriptionally Up-regulating the Exopeptidase DPP4] [Synopsis Glucocorticoids Mobilize Macrophages By Transcriptionally Up-regulating the Exopeptidase DPP4] Diaz-Jimenez D, Petrillo MG, Busada JT, Hermoso MA, Cidlowski JA. March 2020

Multigenerational Reproductive Assessment of 4-methylimidazole Administered in the Diet to Hsd:Sprague Dawley SD Rats [Abstract Multigenerational Reproductive Assessment of 4-methylimidazole Administered in the Diet to Hsd:Sprague Dawley SD Rats] [Synopsis Multigenerational Reproductive Assessment of 4-methylimidazole Administered in the Diet to Hsd:Sprague Dawley SD Rats] Behl M, Willson CJ, Cunny H, Foster PMD, McIntyre B, Shackelford C, Shockley KR, McBride S, Turner K, Waidyanatha S, Blystone CR. March 2020

Single Molecule Analysis Reveals Monomeric XPA Bends DNA and Undergoes Episodic Linear Diffusion During Damage Search [Abstract Single Molecule Analysis Reveals Monomeric XPA Bends DNA and Undergoes Episodic Linear Diffusion During Damage Search] [Synopsis Single Molecule Analysis Reveals Monomeric XPA Bends DNA and Undergoes Episodic Linear Diffusion During Damage Search] Beckwitt EC, Jang S, Carnaval Deweiler I, Kuper J, Sauer F, Simon N, Bretzler J, Watkins SC, Carell T, Kisker C, Van Houten B. March 2020

Uterine Patterning, Endometrial Gland Development, and Implantation Failure in Mice Exposed Neonatally to Genistein [Abstract Uterine Patterning, Endometrial Gland Development, and Implantation Failure in Mice Exposed Neonatally to Genistein] [Synopsis Uterine Patterning, Endometrial Gland Development, and Implantation Failure in Mice Exposed Neonatally to Genistein] [Story Uterine Patterning, Endometrial Gland Development, and Implantation Failure in Mice Exposed Neonatally to Genistein] Jefferson WN, Padilla-Banks E, Suen AA, Royer LJ, Zeldin SM, Arora R, Williams C. March 2020

Alterations in Promoter Interaction Landscape and Transcriptional Network Underlying Metabolic Adaptation to Diet [Abstract Alterations in Promoter Interaction Landscape and Transcriptional Network Underlying Metabolic Adaptation to Diet] [Synopsis Alterations in Promoter Interaction Landscape and Transcriptional Network Underlying Metabolic Adaptation to Diet] [Story Alterations in Promoter Interaction Landscape and Transcriptional Network Underlying Metabolic Adaptation to Diet] Qin Y, Grimm SA, Roberts JD, Chrysovergis K, Wade PA. February 2020

Association Between Ambient Air Pollution and Breast Cancer Risk: The Multiethnic Cohort Study [Abstract Association Between Ambient Air Pollution and Breast Cancer Risk: The Multiethnic Cohort Study] [Synopsis Association Between Ambient Air Pollution and Breast Cancer Risk: The Multiethnic Cohort Study] Cheng I, Tseng C, Wu J, Yang J, Conroy SM, Shariff-Marco S, Li L, Hertz A, Gomez SL, Le Marchand L, Whittemore AS, Stram DO, Ritz B, Wu AH. February 2020

Bisphenol A Activates an Innate Viral Immune Response Pathway [Abstract Bisphenol A Activates an Innate Viral Immune Response Pathway] [Synopsis Bisphenol A Activates an Innate Viral Immune Response Pathway] Sowers ML, Tang H, Tian B, Goldblum R, Midoro-Horiuti T, Zhang K. February 2020

Control of XPR1-dependent Cellular Phosphate Efflux by InsP8 Is an Exemplar for Functionally-exclusive Inositol Pyrophosphate Signaling [Abstract Control of XPR1-dependent Cellular Phosphate Efflux by InsP8 Is an Exemplar for Functionally-exclusive Inositol Pyrophosphate Signaling] [Synopsis Control of XPR1-dependent Cellular Phosphate Efflux by InsP8 Is an Exemplar for Functionally-exclusive Inositol Pyrophosphate Signaling] Li X, Gu C, Hostachy S, Sahu S, Wittwer C, Jessen HJ, Fiedler D, Wang H, Shears SB. February 2020

Dynamic Transcriptome, Accessible Genome, and PGR Cistrome Profiles in the Human Myometrium [Abstract Dynamic Transcriptome, Accessible Genome, and PGR Cistrome Profiles in the Human Myometrium] [Synopsis Dynamic Transcriptome, Accessible Genome, and PGR Cistrome Profiles in the Human Myometrium] Wu SP, Anderson ML, Wang T, Zhou L, Emery OM, Li X, DeMayo FJ. February 2020

Estrogen-induced Transcription at Individual Alleles Is Independent of Receptor Level and Active Conformation but Can Be Modulated by Coactivators Activity [Abstract Estrogen-induced Transcription at Individual Alleles Is Independent of Receptor Level and Active Conformation but Can Be Modulated by Coactivators Activity] [Synopsis Estrogen-induced Transcription at Individual Alleles Is Independent of Receptor Level and Active Conformation but Can Be Modulated by Coactivators Activity] Stossi F, Dandekar RD, Mancini MG, Gu G, Fuqua SAW, Nardone A, DeAngelis C, Fu X, Schiff R, Bedford MT, Xu W, Johansson HE, Stephan CC, Mancini MA. February 2020

Evaluation of Maternal, Embryo, and Placental Effects in CD-1 Mice Following Gestational Exposure to Perfluorooctanoic Acid (PFOA) or Hexafluoropropylene Oxide Dimer Acid (HFPO-DA or GenX) [Abstract Evaluation of Maternal, Embryo, and Placental Effects in CD-1 Mice Following Gestational Exposure to Perfluorooctanoic Acid (PFOA) or Hexafluoropropylene Oxide Dimer Acid (HFPO-DA or GenX)] [Synopsis Evaluation of Maternal, Embryo, and Placental Effects in CD-1 Mice Following Gestational Exposure to Perfluorooctanoic Acid (PFOA) or Hexafluoropropylene Oxide Dimer Acid (HFPO-DA or GenX)] Blake BE, Cope HA, Hall SM, Keys RD, Mahler RD, McCord J, Scott B, Stapleton HM, Strynar MJ, Elmore SA, Fenton SE. February 2020

NRF2 Activates Growth Factor Genes and Downstream AKT Signaling to Induce Mouse and Human Hepatomegly [Abstract NRF2 Activates Growth Factor Genes and Downstream AKT Signaling to Induce Mouse and Human Hepatomegly] [Synopsis NRF2 Activates Growth Factor Genes and Downstream AKT Signaling to Induce Mouse and Human Hepatomegly] He F, Antonucci L, Yamachika S, Zhang Z, Taniguchi K, Umemura A, Hatzivassiliou G, Roose-Girma M, Reina-Campos M, Duran A, Diaz-Meco MT, Moscat J, Sun B, Karin M. February 2020

Perfluorooctane Sulfonate Alters Gut Microbiota-Host Metabolic Homeostasis in Mice [Abstract Perfluorooctane Sulfonate Alters Gut Microbiota-Host Metabolic Homeostasis in Mice] [Synopsis Perfluorooctane Sulfonate Alters Gut Microbiota-Host Metabolic Homeostasis in Mice] Zhang L, Rimal B, Nichols RG, Tian Y, Smith PB, Hatzakis E, Chang SC, Butenhoff JL, Peters JM, Patterson AD. February 2020

Effects of Benzophenone-3 and Propylparaben on Estrogen Receptor-Dependent R-Loops and DNA Damage in Breast Epithelial Cells and Mice [Abstract Effects of Benzophenone-3 and Propylparaben on Estrogen Receptor-Dependent R-Loops and DNA Damage in Breast Epithelial Cells and Mice] [Synopsis Effects of Benzophenone-3 and Propylparaben on Estrogen Receptor-Dependent R-Loops and DNA Damage in Breast Epithelial Cells and Mice] Majhi PD, Sharma A, Roberts AL, Daniele E, Majewski AR, Chuong LM, Black AL, Vandenberg LN, Schneider SS, Dunphy KA, Jerry DJ. January 2020

Epithelial Membrane Protein 2 Governs Transepithelial Migration of Neutrophils into the Airspace [Abstract Epithelial Membrane Protein 2 Governs Transepithelial Migration of Neutrophils into the Airspace] [Synopsis Epithelial Membrane Protein 2 Governs Transepithelial Migration of Neutrophils into the Airspace] Lin WC, Gowdy KM, Madenspacher JH, Zemans RL, Yamamoto K, Lyons-Cohen M, Nakano H, Janardhan K, Williams CJ, Cook DN, Mizgerd JP, Fessler MB. January 2020

N6-methyladenosine of Chromosome-Associated Regulatory RNA Regulates Chromatin State and Transcription [Abstract N6-methyladenosine of Chromosome-Associated Regulatory RNA Regulates Chromatin State and Transcription] [Synopsis N6-methyladenosine of Chromosome-Associated Regulatory RNA Regulates Chromatin State and Transcription] Liu J, Dou X, Chen C, Chen C, Liu C, Xu MM, Zhao S, Shen B, Gao Y, Han D, He C. January 2020

Particulate Matter and Episodic Memory Decline Mediated by Early Neuroanatomic Biomarkers of Alzheimer’s Disease [Abstract Particulate Matter and Episodic Memory Decline Mediated by Early Neuroanatomic Biomarkers of Alzheimer’s Disease] [Synopsis Particulate Matter and Episodic Memory Decline Mediated by Early Neuroanatomic Biomarkers of Alzheimer’s Disease] Younan D, Petkus AJ, Widaman KF, Wang X, Casanova R, Espeland MA, Gatz M, Henderson VW, Manson JE, Rapp SR, Sachs BC, Serre ML, Gaussoin SA, Barnard R, Saldana S, Vizuete W, Beavers DP, Salinas JA, Chui HC, Renick SM, Shumaker SA, Chen JC. January 2020

Privacy Risks of Sharing Data from Environmental Health Studies [Abstract Privacy Risks of Sharing Data from Environmental Health Studies] [Synopsis Privacy Risks of Sharing Data from Environmental Health Studies] Boronow KE, Perovich LJ, Sweeney L, Yoo JS, Rudel RA, Brown P, Brody JG. January 2020

Proteasome Inhibition Creates a Chromatin Landscape Favorable to RNA Pol II Processivity [Abstract Proteasome Inhibition Creates a Chromatin Landscape Favorable to RNA Pol II Processivity] [Synopsis Proteasome Inhibition Creates a Chromatin Landscape Favorable to RNA Pol II Processivity] Kinyamu HK, Bennett BD, Bushel PR, Archer TK. January 2020

Association of Long-Term Ambient Ozone Exposure With Respiratory Morbidity in Smokers [Abstract Association of Long-Term Ambient Ozone Exposure With Respiratory Morbidity in Smokers] [Synopsis Association of Long-Term Ambient Ozone Exposure With Respiratory Morbidity in Smokers] Paulin LM, Gassett AJ, Alexis NE, Kirwa K, Kanner RE, Peters S, Krishnan JA, Paine R 3rd, Dransfield M, Woodruff PG, Cooper CB, Barr RG, Comellas AP, Pirozzi CS, Han M, Hoffman EA, Martinez FJ, Woo H, Peng RD, Fawzy A, Putcha N, Breysse PN, Kaufman JD, Hansel NN, for SPIROMICS investigators. December 2019

A Truncating Mutation in the Autophagy Gene UVRAG Drives Inflammation and Tumorigenesis In Mice [Abstract A Truncating Mutation in the Autophagy Gene UVRAG Drives Inflammation and Tumorigenesis In Mice] [Synopsis A Truncating Mutation in the Autophagy Gene UVRAG Drives Inflammation and Tumorigenesis In Mice] Quach C, Song Y, Guo H, Li S, Maazi H, Fung M, Sands N, O’Connell D, Restrepo-Vassalli S, Chai B, Nemecio D, Punj V, Akbari O, Idos GE, Mumenthaler SM, Wu N, Martin SE, Hagiya A, Hicks J, Cui H, Liang C. December 2019

CDSeq: A Novel Complete Deconvolution Method for Dissecting Heterogeneous Samples Using Gene Expression Data [Abstract CDSeq: A Novel Complete Deconvolution Method for Dissecting Heterogeneous Samples Using Gene Expression Data] [Synopsis CDSeq: A Novel Complete Deconvolution Method for Dissecting Heterogeneous Samples Using Gene Expression Data] Kang K, Meng Q, Shats I, Umbach DM, Li M, Li Y, Li X, Li L. December 2019

DNA Crosslinkomics: A Tool for the Comprehensive Assessment of Interstrand Crosslinks Using High Resolution Mass Spectrometry [Abstract DNA Crosslinkomics: A Tool for the Comprehensive Assessment of Interstrand Crosslinks Using High Resolution Mass Spectrometry] [Synopsis DNA Crosslinkomics: A Tool for the Comprehensive Assessment of Interstrand Crosslinks Using High Resolution Mass Spectrometry] Hu CW, Chang YJ, Cooke MS, Chao MR. December 2019

Hair Dye and Chemical Straightener Use and Breast Cancer Risk In a Large U.S. Population of Black and White Women [Abstract Hair Dye and Chemical Straightener Use and Breast Cancer Risk In a Large U.S. Population of Black and White Women] [Synopsis Hair Dye and Chemical Straightener Use and Breast Cancer Risk In a Large U.S. Population of Black and White Women] [Story Hair Dye and Chemical Straightener Use and Breast Cancer Risk In a Large U.S. Population of Black and White Women] Eberle CE, Sandler DP, Taylor KW, White AJ. December 2019

Hepatic Transcriptomic Patterns in the Neonatal Rat After Pentabromodiphenyl Ether Exposure [Abstract Hepatic Transcriptomic Patterns in the Neonatal Rat After Pentabromodiphenyl Ether Exposure] [Synopsis Hepatic Transcriptomic Patterns in the Neonatal Rat After Pentabromodiphenyl Ether Exposure] Dunnick JK, Shockley KR, Morgan DL, Travlos GS, Gerrish K, Ton TT, Wilson R, Brar SS, Brix AE, Waidyanatha S, Mutlu E, Pandiri AKR. December 2019

Joint Impact of Phthalate Exposure and Stressful Life Events in Pregnancy on Preterm Birth [Abstract Joint Impact of Phthalate Exposure and Stressful Life Events in Pregnancy on Preterm Birth] [Synopsis Joint Impact of Phthalate Exposure and Stressful Life Events in Pregnancy on Preterm Birth] Ferguson KK, Rosen EM, Barrett ES, Nguyen RHN, Bush N, McElrath TF, Swan SH, Sathyanarayana S. December 2019

Metabolic Control of Astrocyte Pathogenic Activity Via cPLA2-MAVS [Abstract Metabolic Control of Astrocyte Pathogenic Activity Via cPLA2-MAVS] [Synopsis Metabolic Control of Astrocyte Pathogenic Activity Via cPLA2-MAVS] Chao CC, Gutierrez-Vazquez C, Rothhammer V, Mayo L, Wheeler MA, Tjon EC, Zandee SEJ, Blain M, de Lima KA, Takenaka MC, Avila-Pacheco J, Hewson P, Liu L, Sanmarco LM, Borucki DM, Lipof GZ, Trauger SA, Clish CB, Antel JP, Prat A, Quintana FJ. December 2019

Sensitive CometChip Assay for Screening Potentially Carcinogenic DNA Adducts by Trapping DNA Repair Intermediates [Abstract Sensitive CometChip Assay for Screening Potentially Carcinogenic DNA Adducts by Trapping DNA Repair Intermediates] [Synopsis Sensitive CometChip Assay for Screening Potentially Carcinogenic DNA Adducts by Trapping DNA Repair Intermediates] Ngo LP, Owiti NA, Swartz C, Winters J, Su Y, Ge J, Xiong A, Han J, Recio L, Samson LD, Engelward BP. December 2019

Air Pollution, Particulate Matter Composition and Methylation-Based Biologic Age [Abstract Air Pollution, Particulate Matter Composition and Methylation-Based Biologic Age] [Synopsis Air Pollution, Particulate Matter Composition and Methylation-Based Biologic Age] White AJ, Kresovich JK, Keller JP, Xu Z, Kaufman JD, Weinberg CR, Taylor JA, Sandler DP. November 2019

Environmental Phthalate Exposure and Preterm Birth in the PROTECT Birth Cohort [Abstract Environmental Phthalate Exposure and Preterm Birth in the PROTECT Birth Cohort] [Synopsis Environmental Phthalate Exposure and Preterm Birth in the PROTECT Birth Cohort] Ferguson KK, Rosen EM, Rosario Z, Feric Z, Calafat AM, McElrath TF, Velez Vega C, Cordero JF, Alshawabkeh A, Meeker JD. November 2019

Novel Role For Mineralocorticoid Receptors in Controls of a Neuronal Phenotype [Abstract Novel Role For Mineralocorticoid Receptors in Controls of a Neuronal Phenotype] [Synopsis Novel Role For Mineralocorticoid Receptors in Controls of a Neuronal Phenotype] McCann KE, Lustberg DJ, Shaughnessy EK, Carstens KE, Farris S, Alexander GM, Radzicki D, Zhao M, Dudek SM. November 2019

RUNX1 Maintains the Identity of the Fetal Ovary Through an Interplay with FOXL2 [Abstract RUNX1 Maintains the Identity of the Fetal Ovary Through an Interplay with FOXL2] [Synopsis RUNX1 Maintains the Identity of the Fetal Ovary Through an Interplay with FOXL2] Nicol B, Grimm SA, Chalmel F, Lecluze E, Pannetier M, Pailhoux E, Dupin-De-Beyssat E, Guiguen Y, Capel B, Yao HH. November 2019

Sex-Specific Effects of Perinatal FireMaster® 550 (FM550) Exposure on Socioemotional Behavior in Prairie Voles [Abstract Sex-Specific Effects of Perinatal FireMaster® 550 (FM550) Exposure on Socioemotional Behavior in Prairie Voles] [Synopsis Sex-Specific Effects of Perinatal FireMaster® 550 (FM550) Exposure on Socioemotional Behavior in Prairie Voles] Gillera SEA, Marinello WP, Horman BM, Phillips AL, Ruis MT, Stapleton HM, Reif DM, Patisaul HB. November 2019

Toxicokinetics of Perfluorohexanoic Acid (PFHxA), Perfluorooctanoic Acid (PFOA) and Perfluorodecanoic Acid (PFDA) in Male and Female Hsd:Sprague Dawley SD Rats Following Intravenous or Gavage Administration [Abstract Toxicokinetics of Perfluorohexanoic Acid (PFHxA), Perfluorooctanoic Acid (PFOA) and Perfluorodecanoic Acid (PFDA) in Male and Female Hsd:Sprague Dawley SD Rats Following Intravenous or Gavage Administration] [Synopsis Toxicokinetics of Perfluorohexanoic Acid (PFHxA), Perfluorooctanoic Acid (PFOA) and Perfluorodecanoic Acid (PFDA) in Male and Female Hsd:Sprague Dawley SD Rats Following Intravenous or Gavage Administration] Dzierlenga AL, Robinson VG, Waidyanatha S, DeVito MJ, Eifrid MA, Gibbs ST, Granville CA, Blystone CR. November 2019

Transethnic Associations Among Immune-Mediated Diseases and Single-Nucleotide Polymorphisms of the Aryl Hydrocarbon Response Gene ARNT and the PTPN22 Immune Regulatory Gene [Abstract Transethnic Associations Among Immune-Mediated Diseases and Single-Nucleotide Polymorphisms of the Aryl Hydrocarbon Response Gene ARNT and the PTPN22 Immune Regulatory Gene] [Synopsis Transethnic Associations Among Immune-Mediated Diseases and Single-Nucleotide Polymorphisms of the Aryl Hydrocarbon Response Gene ARNT and the PTPN22 Immune Regulatory Gene] Schurman SH, O’Hanlon TP, McGrath JA, Gruzdev A, Bektas A, Xu H, Garantziotis S, Zeldin DC, Miller FW. November 2019

Two-Tiered Enforcement of High-Fidelity DNA Ligation [Abstract Two-Tiered Enforcement of High-Fidelity DNA Ligation] [Synopsis Two-Tiered Enforcement of High-Fidelity DNA Ligation] Tumbale PP, Jurkiw TJ, Schellenberg MJ, Riccio AA, O’Brien PJ, Williams RS. November 2019

A Prospective Analysis of Red and Processed Meat Consumption and Risk of Colorectal Cancer in Women [Abstract A Prospective Analysis of Red and Processed Meat Consumption and Risk of Colorectal Cancer in Women] [Synopsis A Prospective Analysis of Red and Processed Meat Consumption and Risk of Colorectal Cancer in Women] Mehta SS, Arroyave WD, Lunn RM, Park YM, Boyd WA, Sandler DP. October 2019

Developmental Toxicity Assessment of Piperonyl Butoxide Exposure Targeting Sonic Hedgehog Signaling and Forebrain and Face Morphogenesis in the Mouse: An In Vitro and In Vivo Study [Abstract Developmental Toxicity Assessment of Piperonyl Butoxide Exposure Targeting Sonic Hedgehog Signaling and Forebrain and Face Morphogenesis in the Mouse: An In Vitro and In Vivo Study] [Synopsis Developmental Toxicity Assessment of Piperonyl Butoxide Exposure Targeting Sonic Hedgehog Signaling and Forebrain and Face Morphogenesis in the Mouse: An In Vitro and In Vivo Study] Everson JL, Sun MR, Fink DM, Heyne GW, Melberg CG, Nelson KF, Doroodchi P, Colopy LJ, Ulschmid CM, Martin AA, McLaughlin MT, Lipinski RJ. October 2019

Early Breast Development in Overweight Girls: Does Estrogen Made By Adipose Tissue Play a Role? [Abstract Early Breast Development in Overweight Girls: Does Estrogen Made By Adipose Tissue Play a Role?] [Synopsis Early Breast Development in Overweight Girls: Does Estrogen Made By Adipose Tissue Play a Role?] [Story Early Breast Development in Overweight Girls: Does Estrogen Made By Adipose Tissue Play a Role?] Carlson L, Flores Poccia V, Sun BZ, Mosley B, Kirste I, Rice A, Sridhar R, Kangarloo T, Vesper HW, Duke L, Botelho JC, Filie AC, Adams JM, Shaw ND. October 2019

Electronic-Cigarette Smoke Induces Lung Adenocarcinoma and Bladder Urothelial Hyperplasia in Mice [Abstract Electronic-Cigarette Smoke Induces Lung Adenocarcinoma and Bladder Urothelial Hyperplasia in Mice] [Synopsis Electronic-Cigarette Smoke Induces Lung Adenocarcinoma and Bladder Urothelial Hyperplasia in Mice] Tang MS, Wu XR, Lee HW, Xia Y, Deng FM, Moreira AL, Chen LC, Huang WC, Lepor H. October 2019

Airborne Mammary Carcinogens and Breast Cancer Risk in the Sister Study [Abstract Airborne Mammary Carcinogens and Breast Cancer Risk in the Sister Study] [Synopsis Airborne Mammary Carcinogens and Breast Cancer Risk in the Sister Study] Niehoff NM, Gammon MD, Keil AP, Nichols HB, Engel LS, Sandler DP, White AJ. September 2019

Chemoptogenetic Damage to Mitochondria Causes Rapid Telomere Dysfunction [Abstract Chemoptogenetic Damage to Mitochondria Causes Rapid Telomere Dysfunction] [Synopsis Chemoptogenetic Damage to Mitochondria Causes Rapid Telomere Dysfunction] [Story Chemoptogenetic Damage to Mitochondria Causes Rapid Telomere Dysfunction] Qian W, Kumar N, Roginskaya V, Fouquerel E, Opresko PL, Shiva S, Watkins SC, Kolodieznyi D, Bruchez MP, Van Houten B. September 2019

Cryo-EM Reveals Active Site Coordination Within a Multienzyme Pre-rRNA Processing Complex [Abstract Cryo-EM Reveals Active Site Coordination Within a Multienzyme Pre-rRNA Processing Complex] [Synopsis Cryo-EM Reveals Active Site Coordination Within a Multienzyme Pre-rRNA Processing Complex] Pillon MC, Hsu AL, Krahn JM, Williams JG, Goslen KH, Sobhany M, Borgnia MJ, Stanley RE. September 2019

Metatranscriptomic Analyses of Diel Metabolic Functions During a Microcystis Bloom in Western Lake Erie [Abstract Metatranscriptomic Analyses of Diel Metabolic Functions During a Microcystis Bloom in Western Lake Erie] [Synopsis Metatranscriptomic Analyses of Diel Metabolic Functions During a Microcystis Bloom in Western Lake Erie] Davenport EJ, Neudeck MJ, Matson PG, Bullerjahn GS, Davis TW, Wilhelm SW, Denney MK, Krausfeldt LE, Stough JMA, Meyer KA, Dick GJ, Johengen TH, Lindquist E, Tringe SG, McKay RML. September 2019

Multi-Walled Carbon Nanotubes Upregulate Mitochondrial Gene Expression and Trigger Mitochondrial Dysfunction in Primary Human Bronchial Epithelial Cells [Abstract Multi-Walled Carbon Nanotubes Upregulate Mitochondrial Gene Expression and Trigger Mitochondrial Dysfunction in Primary Human Bronchial Epithelial Cells] [Synopsis Multi-Walled Carbon Nanotubes Upregulate Mitochondrial Gene Expression and Trigger Mitochondrial Dysfunction in Primary Human Bronchial Epithelial Cells] Snyder RJ, Verhein KC, Vellers HL, Burkholder AB, Garantziotis S, Kleeberger SR. September 2019

Physico-Chemical Properties and Gestational Diabetes Predict Transplacental Transfer and Partitioning of Perfluoroalkyl Substances [Abstract Physico-Chemical Properties and Gestational Diabetes Predict Transplacental Transfer and Partitioning of Perfluoroalkyl Substances] [Synopsis Physico-Chemical Properties and Gestational Diabetes Predict Transplacental Transfer and Partitioning of Perfluoroalkyl Substances] Eryasa B, Grandjean P, Nielsen F, Valvi D, Zmirou-Navier D, Sunderland E, Weihe P, Oulhote Y. September 2019

Prenatal Exposure to Organophosphate Pesticides and Functional Neuroimaging in Adolescents Living in Proximity to Pesticide Application [Abstract Prenatal Exposure to Organophosphate Pesticides and Functional Neuroimaging in Adolescents Living in Proximity to Pesticide Application] [Synopsis Prenatal Exposure to Organophosphate Pesticides and Functional Neuroimaging in Adolescents Living in Proximity to Pesticide Application] Sagiv SK, Bruno JL, Baker JM, Palzes V, Kogut K, Rauch S, Gunier R, Mora AM, Reiss AL, Eskenazi B. September 2019

Renal Clearable Catalytic Gold Nanoclusters For In Vivo Disease Monitoring [Abstract Renal Clearable Catalytic Gold Nanoclusters For In Vivo Disease Monitoring] [Synopsis Renal Clearable Catalytic Gold Nanoclusters For In Vivo Disease Monitoring] Loynachan CN, Soleimany AP, Dudani JS, Lin Y, Najer A, Bekdemir A, Chen Q, Bhatia SN, Stevens MM. September 2019

Roles For DNA Polymerase Delta In Initiating and Terminating Leading Strand DNA Replication [Abstract Roles For DNA Polymerase Delta In Initiating and Terminating Leading Strand DNA Replication] [Synopsis Roles For DNA Polymerase Delta In Initiating and Terminating Leading Strand DNA Replication] Zhou ZX, Lujan SA, Burkholder AB, Garbacz MA, Kunkel TA. September 2019

A Crystal Structure of a Collaborative RNA Regulatory Complex Reveals Mechanisms To Refine Target Specificity [Abstract A Crystal Structure of a Collaborative RNA Regulatory Complex Reveals Mechanisms To Refine Target Specificity] [Synopsis A Crystal Structure of a Collaborative RNA Regulatory Complex Reveals Mechanisms To Refine Target Specificity] Qiu C, Bhat VD, Rajeev S, Zhang C, Lasley AE, Wine RN, Campbell ZT, Hall TMT. August 2019

An Overview of Methods to Address Distinct Research Questions On Environmental Mixtures: An Application To Persistent Organic Pollutants and Leukocyte Telomere Length [Abstract An Overview of Methods to Address Distinct Research Questions On Environmental Mixtures: An Application To Persistent Organic Pollutants and Leukocyte Telomere Length] [Synopsis An Overview of Methods to Address Distinct Research Questions On Environmental Mixtures: An Application To Persistent Organic Pollutants and Leukocyte Telomere Length] Gibson EA, Nunez Y, Abuawad A, Zota AR, Renzetti S, Devick KL, Gennings C, Goldsmith J, Coull BA, Kioumourtzoglou MA. August 2019

Association Between Maternal Fluoride Exposure During Pregnancy and IQ Scores in Offspring in Canada [Abstract Association Between Maternal Fluoride Exposure During Pregnancy and IQ Scores in Offspring in Canada] [Synopsis Association Between Maternal Fluoride Exposure During Pregnancy and IQ Scores in Offspring in Canada] Green R, Lanphear B, Hornung R, Flora D, Martinez-Mier EA, Neufeld R, Ayotte P, Muckle G, Till C. August 2019

Damage Sensor Role of UV-DDB During Base Excision Repair [Abstract Damage Sensor Role of UV-DDB During Base Excision Repair] [Synopsis Damage Sensor Role of UV-DDB During Base Excision Repair] [Story Damage Sensor Role of UV-DDB During Base Excision Repair] Jang S, Kumar N, Beckwitt EC, Kong M, Fouquerel E, Rapic-Otrin V, Prasad R, Watkins SC, Khuu C, Majumdar C, David SS, Wilson SH, Bruchez MP, Opresko PL, Van Houten B. August 2019

Evaluating Sufficient Similarity of Botanical Dietary Supplements: Combining Chemical and In Vitro Biological Data [Abstract Evaluating Sufficient Similarity of Botanical Dietary Supplements: Combining Chemical and In Vitro Biological Data] [Synopsis Evaluating Sufficient Similarity of Botanical Dietary Supplements: Combining Chemical and In Vitro Biological Data] Ryan KR, Huang MC, Ferguson SS, Waidyanatha S, Ramaiahgari S, Rice JR, Dunlap PE, Auerbach SS, Mutlu E, Cristy T, Peirfelice J, DeVito MJ, Smith-Roe SL, Rider CV. August 2019

Genome-Wide Promoter DNA Methylation Profiling of Hepatocellular Carcinomas Arising Either Spontaneously or Due to Chronic Exposure to Ginkgo Biloba Extract (GBE) in B6C3F1/N Mice [Abstract Genome-Wide Promoter DNA Methylation Profiling of Hepatocellular Carcinomas Arising Either Spontaneously or Due to Chronic Exposure to Ginkgo Biloba Extract (GBE) in B6C3F1/N Mice] [Synopsis Genome-Wide Promoter DNA Methylation Profiling of Hepatocellular Carcinomas Arising Either Spontaneously or Due to Chronic Exposure to Ginkgo Biloba Extract (GBE) in B6C3F1/N Mice] Kovi RC, Bhusari S, Mav D, Shah RR, Ton TV, Hoenerhoff MJ, Sills RC, Pandiri AR. August 2019

Organophosphate Pesticide Exposure in Pregnancy in Association with Ultrasound and Delivery Measures of Fetal Growth [Abstract Organophosphate Pesticide Exposure in Pregnancy in Association with Ultrasound and Delivery Measures of Fetal Growth] [Synopsis Organophosphate Pesticide Exposure in Pregnancy in Association with Ultrasound and Delivery Measures of Fetal Growth] Ferguson KK, van den Dries MA, Gaillard R, Pronk A, Spaan S, Tiemeier H, Jaddoe VWV. August 2019

Prostate Cancer in World Trade Center Responders Demonstrates Evidence of an Inflammatory Cascade [Abstract Prostate Cancer in World Trade Center Responders Demonstrates Evidence of an Inflammatory Cascade] [Synopsis Prostate Cancer in World Trade Center Responders Demonstrates Evidence of an Inflammatory Cascade] Gong Y, Wang L, Yu H, Albert N, Cohen MD, Prophete C, Horton L, Sisco M, Park SH, Lee HW, Zelikoff J, Chen LC, Hashim D, Suarez-Farinas M, Donovan MJ, Aaronson SA, Galsky M, Zhu J, Taioli E, Oh WK. August 2019

Silicone Pet Tags Associate Tris(1,3-dichloro-2-isopropyl) Phosphate Exposures with Feline Hyperthyroidism [Abstract Silicone Pet Tags Associate Tris(1,3-dichloro-2-isopropyl) Phosphate Exposures with Feline Hyperthyroidism] [Synopsis Silicone Pet Tags Associate Tris(1,3-dichloro-2-isopropyl) Phosphate Exposures with Feline Hyperthyroidism] Poutasse CM, Herbstman JB, Peterson ME, Gordon J, Soboroff PH, Holmes D, Gonzalez D, Tidwell LG, Anderson KA. August 2019

The Landscape of Genetic Content in the Gut and Oral Human Microbiome [Abstract The Landscape of Genetic Content in the Gut and Oral Human Microbiome] [Synopsis The Landscape of Genetic Content in the Gut and Oral Human Microbiome] Tierney BT, Yang Z, Luber JM, Beaudin M, Wibowo MC, Baek C, Mehlenbacher E, Patel CJ, Kostic AD. August 2019

Beta-Arrestin-1 Inhibits Glucocorticoid Receptor Turnover and Alters Glucocorticoid Signaling [Abstract Beta-Arrestin-1 Inhibits Glucocorticoid Receptor Turnover and Alters Glucocorticoid Signaling] [Synopsis Beta-Arrestin-1 Inhibits Glucocorticoid Receptor Turnover and Alters Glucocorticoid Signaling] Petrillo MG, Oakley RH, Cidlowski JA. July 2019

Distinct RNA-binding Modules in a Single PUF Protein Cooperate to Determine RNA Specificity [Abstract Distinct RNA-binding Modules in a Single PUF Protein Cooperate to Determine RNA Specificity] [Synopsis Distinct RNA-binding Modules in a Single PUF Protein Cooperate to Determine RNA Specificity] Qiu C, Dutcher RC, Porter DF, Arava Y, Wickens M, Hall TMT. July 2019

Inhalation Exposure to Multi-Walled Carbon Nanotubes Alters the Pulmonary Allergic Response of Mice to House Dust Mite Allergen [Abstract Inhalation Exposure to Multi-Walled Carbon Nanotubes Alters the Pulmonary Allergic Response of Mice to House Dust Mite Allergen] [Synopsis Inhalation Exposure to Multi-Walled Carbon Nanotubes Alters the Pulmonary Allergic Response of Mice to House Dust Mite Allergen] Ihrie MD, Taylor-Just AJ, Walker NJ, Stout MD, Gupta A, Richey JS, Hayden BK, Baker GL, Sparrow BR, Duke KS, Bonner JC. July 2019

A Distal Super Enhancer Mediates Estrogen-Dependent Mouse Uterine-Specific Gene Transcription of Igf1 (Insulin-Like Growth Factor 1) [Abstract A Distal Super Enhancer Mediates Estrogen-Dependent Mouse Uterine-Specific Gene Transcription of Igf1 (Insulin-Like Growth Factor 1)] [Synopsis A Distal Super Enhancer Mediates Estrogen-Dependent Mouse Uterine-Specific Gene Transcription of Igf1 (Insulin-Like Growth Factor 1)] Hewitt SC, Lierz SL, Garcia M, Hamilton KJ, Gruzdev A, Grimm SA, Lydon JP, DeMayo FJ, Korach KS. June 2019

A Small Molecule Targeting Mutagenic Translesion Synthesis Improves Chemotherapy [Abstract A Small Molecule Targeting Mutagenic Translesion Synthesis Improves Chemotherapy] [Synopsis A Small Molecule Targeting Mutagenic Translesion Synthesis Improves Chemotherapy] Wojtaszek JL, Chatterjee N, Najeeb J, Ramos A, Lee M, Bian K, Xue JY, Fenton BA, Park H, Li D, Hemann MT, Hong J, Walker GC, Zhou P. June 2019

Continuing Medical Education as a Translational Science Opportunity for Health Communication Researchers: The BCERP Model [Abstract Continuing Medical Education as a Translational Science Opportunity for Health Communication Researchers: The BCERP Model] [Synopsis Continuing Medical Education as a Translational Science Opportunity for Health Communication Researchers: The BCERP Model] Silk KJ, Walling B, Totzkay D, Mulroy M, Smith SW, Quaderer T, Boumis J, Thomas B. June 2019

Effect of a 24-Week Randomized Trial of an Organic Produce Intervention on Pyrethroid and Organophosphate Pesticide Exposure Among Pregnant Women [Abstract Effect of a 24-Week Randomized Trial of an Organic Produce Intervention on Pyrethroid and Organophosphate Pesticide Exposure Among Pregnant Women] [Synopsis Effect of a 24-Week Randomized Trial of an Organic Produce Intervention on Pyrethroid and Organophosphate Pesticide Exposure Among Pregnant Women] Curl CL, Porter J, Penwell I, Phinney R, Ospina M, Calafat AM. June 2019

Metabolomics of Neonatal Blood Spots Reveal Distinct Phenotypes of Pediatric Acute Lymphoblastic Leukemia and Potential Effects of Early-Life Nutrition [Abstract Metabolomics of Neonatal Blood Spots Reveal Distinct Phenotypes of Pediatric Acute Lymphoblastic Leukemia and Potential Effects of Early-Life Nutrition] [Synopsis Metabolomics of Neonatal Blood Spots Reveal Distinct Phenotypes of Pediatric Acute Lymphoblastic Leukemia and Potential Effects of Early-Life Nutrition] Petrick LM, Schiffman C, Edmands WMB, Yano Y, Perttula K, Whitehead T, Metayer C, Wheelock CE, Arora M, Grigoryan H, Carlsson H, Dudoit S, Rappaport SM. June 2019

Mitochondrial Stress Response in Neural Stem Cells Exposed to Electronic Cigarettes [Abstract Mitochondrial Stress Response in Neural Stem Cells Exposed to Electronic Cigarettes] [Synopsis Mitochondrial Stress Response in Neural Stem Cells Exposed to Electronic Cigarettes] Zahedi A, Phandthong R, Chaili A, Leung S, Omaiye E, Talbot P. June 2019

Therapeutic Suppression of Pulmonary Neutrophilia and Allergic Airway Hyperresponsiveness by a RORgamma-t Inverse Agonist [Abstract Therapeutic Suppression of Pulmonary Neutrophilia and Allergic Airway Hyperresponsiveness by a RORgamma-t Inverse Agonist] [Synopsis Therapeutic Suppression of Pulmonary Neutrophilia and Allergic Airway Hyperresponsiveness by a RORgamma-t Inverse Agonist] Whitehead GS, Kang HS, Thomas SY, Medvedev A, Karcz TP, Izumi G, Nakano K, Makarov SS, Nakano H, Jetten AM, Cook DN. June 2019

Toxicokinetics and Bioavailability of Bisphenol AF Following Oral Administration in Rodents: A Dose, Species, and Sex Comparison [Abstract Toxicokinetics and Bioavailability of Bisphenol AF Following Oral Administration in Rodents: A Dose, Species, and Sex Comparison] [Synopsis Toxicokinetics and Bioavailability of Bisphenol AF Following Oral Administration in Rodents: A Dose, Species, and Sex Comparison] Waidyanatha S, Black SR, Aillon K, Collins B, Patel PR, Riordan F, Sutherland V, Robinson VG, Fernando R, Fennell TR. June 2019

Using Collaborative Cross Mouse Population to Fill Data Gaps in Risk Assessment: A Case Study of Population-Based Analysis of Toxicokinetics and Kidney Toxicodynamics of Tetrachloroethylene [Abstract Using Collaborative Cross Mouse Population to Fill Data Gaps in Risk Assessment: A Case Study of Population-Based Analysis of Toxicokinetics and Kidney Toxicodynamics of Tetrachloroethylene] [Synopsis Using Collaborative Cross Mouse Population to Fill Data Gaps in Risk Assessment: A Case Study of Population-Based Analysis of Toxicokinetics and Kidney Toxicodynamics of Tetrachloroethylene] Luo YS, Cichocki JA, Hsieh NH, Lewis L, Wright FA, Threadgill DW, Chiu WA, Rusyn I. June 2019

Adaptive Introgression Enables Evolutionary Rescue From Extreme Environmental Pollution [Abstract Adaptive Introgression Enables Evolutionary Rescue From Extreme Environmental Pollution] [Synopsis Adaptive Introgression Enables Evolutionary Rescue From Extreme Environmental Pollution] Oziolor EM, Reid NM, Yair S, Lee KM, Guberman VerPloeg S, Bruns PC, Shaw JR, Whitehead A, Matson CW. May 2019

Association of Changes in Air Quality With Incident Asthma in Children in California, 1993-2014 [Abstract Association of Changes in Air Quality With Incident Asthma in Children in California, 1993-2014] [Synopsis Association of Changes in Air Quality With Incident Asthma in Children in California, 1993-2014] Garcia E, Berhane KT, Islam T, McConnell R, Urman R, Chen Z, Gilliland FD. May 2019

Evaluating Cell Lines As Models For Metastatic Breast Cancer Through Integrative Analysis of Genomic Data [Abstract Evaluating Cell Lines As Models For Metastatic Breast Cancer Through Integrative Analysis of Genomic Data] [Synopsis Evaluating Cell Lines As Models For Metastatic Breast Cancer Through Integrative Analysis of Genomic Data] Liu K, Newbury PA, Glicksberg BS, Zeng WZD, Paithankar S, Andrechek ER, Chen B. May 2019

Global Deletion of Optineurin Results In Altered Type I IFN Signaling and Abnormal Bone Remodeling In a Model of Paget’s Disease [Abstract Global Deletion of Optineurin Results In Altered Type I IFN Signaling and Abnormal Bone Remodeling In a Model of Paget’s Disease] [Synopsis Global Deletion of Optineurin Results In Altered Type I IFN Signaling and Abnormal Bone Remodeling In a Model of Paget’s Disease] Wong SW, Huang BW, Hu X, Ho Kim E, Kolb JP, Padilla RJ, Xue P, Wang L, Oguin TH 3rd, Miguez PA, Tseng HC, Ko CC, Martinez J. May 2019

JNK1/2 Represses Lkb1-Deficiency-Induced Lung Squamous Cell Carcinoma Progression [Abstract JNK1/2 Represses Lkb1-Deficiency-Induced Lung Squamous Cell Carcinoma Progression] [Synopsis JNK1/2 Represses Lkb1-Deficiency-Induced Lung Squamous Cell Carcinoma Progression] [Story JNK1/2 Represses Lkb1-Deficiency-Induced Lung Squamous Cell Carcinoma Progression] Liu J, Wang T, Creighton CJ, Wu SP, Ray M, Janardhan KS, Willson CJ, Cho SN, Castro PD, Ittmann MM, Li JL, Davis RJ, DeMayo FJ. May 2019

Multi-Omic Profiling Reveals Dynamics of the Phased Progression of Pluripotency [Abstract Multi-Omic Profiling Reveals Dynamics of the Phased Progression of Pluripotency] [Synopsis Multi-Omic Profiling Reveals Dynamics of the Phased Progression of Pluripotency] [Story Multi-Omic Profiling Reveals Dynamics of the Phased Progression of Pluripotency] Yang P, Humphrey SJ, Cinghu S, Pathania R, Oldfield AJ, Kumar D, Perera D, Yang JYH, James DE, Mann M, Jothi R. May 2019

Arsenite Malignantly Transforms Human Prostate Epithelial Cells In Vitro By Gene Amplification of Mutated KRAS [Abstract Arsenite Malignantly Transforms Human Prostate Epithelial Cells In Vitro By Gene Amplification of Mutated KRAS] [Synopsis Arsenite Malignantly Transforms Human Prostate Epithelial Cells In Vitro By Gene Amplification of Mutated KRAS] Merrick BA, Phadke DP, Bostrom MA, Shah RR, Wright GM, Wang X, Gordon O, Pelch KE, Auerbach SS, Paules RS, DeVito MJ, Waalkes MP, Tokar EJ. April 2019

Arsinothricin, An Arsenic-Containing Non-Proteinogenic Amino Acid Analog of Glutamate, is a Broad-Spectrum Antibiotic [Abstract Arsinothricin, An Arsenic-Containing Non-Proteinogenic Amino Acid Analog of Glutamate, is a Broad-Spectrum Antibiotic] [Synopsis Arsinothricin, An Arsenic-Containing Non-Proteinogenic Amino Acid Analog of Glutamate, is a Broad-Spectrum Antibiotic] Nadar VS, Dheeman DS, Galvan AE, Yoshinaga-Sakurai K, Kandavelu P, Sankaran B, Kuramata M, Ishikawa S, Rosen BP, Yoshinaga M. April 2019

Blood DNA Methylation and Breast Cancer: A Prospective Case-Cohort Analysis in the Sister Study [Abstract Blood DNA Methylation and Breast Cancer: A Prospective Case-Cohort Analysis in the Sister Study] [Synopsis Blood DNA Methylation and Breast Cancer: A Prospective Case-Cohort Analysis in the Sister Study] Xu Z, Sandler DP, Taylor JA. April 2019

Defining UHRF1 Domains That Support Maintenance of Human Colon Cancer DNA Methylation and Oncogenic Properties [Abstract Defining UHRF1 Domains That Support Maintenance of Human Colon Cancer DNA Methylation and Oncogenic Properties] [Synopsis Defining UHRF1 Domains That Support Maintenance of Human Colon Cancer DNA Methylation and Oncogenic Properties] Kong X, Chen J, Xie W, Brown SM, Cai Y, Wu K, Fan D, Nie Y, Yegnasubramanian S, Tiedemann RL, Tao Y, Chiu Yen RW, Topper MJ, Zahnow CA, Easwaran H, Rothbart SB, Xia L, Baylin SB. April 2019

Early Pregnancy Exposure To Endocrine Disrupting Chemical Mixtures Are Associated With Inflammatory Changes in Maternal and Neonatal Circulation [Abstract Early Pregnancy Exposure To Endocrine Disrupting Chemical Mixtures Are Associated With Inflammatory Changes in Maternal and Neonatal Circulation] [Synopsis Early Pregnancy Exposure To Endocrine Disrupting Chemical Mixtures Are Associated With Inflammatory Changes in Maternal and Neonatal Circulation] Kelley AS, Banker M, Goodrich JM, Dolinoy DC, Burant C, Domino SE, Smith YR, Song PXK, Padmanabhan V. April 2019

Environmental Styrene Exposure and Sensory and Motor Function in Gulf Coast Residents [Abstract Environmental Styrene Exposure and Sensory and Motor Function in Gulf Coast Residents] [Synopsis Environmental Styrene Exposure and Sensory and Motor Function in Gulf Coast Residents] Werder EJ, Sandler DP, Richardson DB, Emch ME, Kwok RK, Gerr FE, Engel LS. April 2019

Nonanimal Models for Acute Toxicity Evaluations: Applying Data-Driven Profiling and Read-Across [Abstract Nonanimal Models for Acute Toxicity Evaluations: Applying Data-Driven Profiling and Read-Across] [Synopsis Nonanimal Models for Acute Toxicity Evaluations: Applying Data-Driven Profiling and Read-Across] Russo DP, Strickland J, Karmaus AL, Wang W, Shende S, Hartung T, Aleksunes LM, Zhu H. April 2019

Prenatal and Childhood Exposure to Phthalates and Motor Skills at Age 11 Years [Abstract Prenatal and Childhood Exposure to Phthalates and Motor Skills at Age 11 Years] [Synopsis Prenatal and Childhood Exposure to Phthalates and Motor Skills at Age 11 Years] Balalian AA, Whyatt RM, Liu X, Insel BJ, Rauh VA, Herbstman J, Factor-Litvak P. April 2019

Transposable Elements Drive Widespread Expression of Oncogenes in Human Cancers [Abstract Transposable Elements Drive Widespread Expression of Oncogenes in Human Cancers] [Synopsis Transposable Elements Drive Widespread Expression of Oncogenes in Human Cancers] Jang HS, Shah NM, Du AY, Dailey ZZ, Pehrsson EC, Godoy PM, Zhang D, Li D, Xing X, Kim S, O’Donnell D, Gordon JI, Wang T. April 2019

Tumor Suppressor SMARCB1 Suppresses Super-Enhancers to govern hESC Lineage Determination [Abstract Tumor Suppressor SMARCB1 Suppresses Super-Enhancers to govern hESC Lineage Determination] [Synopsis Tumor Suppressor SMARCB1 Suppresses Super-Enhancers to govern hESC Lineage Determination] Langer LF, Ward JM, Archer TK. April 2019

Dysregulation of Hypothalamic-Pituitary Estrogen Receptor Alpha-Mediated Signaling Causes Episodic LH Secretion and Cystic Ovary [Abstract Dysregulation of Hypothalamic-Pituitary Estrogen Receptor Alpha-Mediated Signaling Causes Episodic LH Secretion and Cystic Ovary] [Synopsis Dysregulation of Hypothalamic-Pituitary Estrogen Receptor Alpha-Mediated Signaling Causes Episodic LH Secretion and Cystic Ovary] Arao Y, Hamilton KJ, Wu SP, Tsai MJ, DeMayo FJ, Korach KS. March 2019

Endogenous Glucocorticoids Prevent Gastric Metaplasia by Suppressing Spontaneous Inflammation [Abstract Endogenous Glucocorticoids Prevent Gastric Metaplasia by Suppressing Spontaneous Inflammation] [Synopsis Endogenous Glucocorticoids Prevent Gastric Metaplasia by Suppressing Spontaneous Inflammation] Busada JT, Ramamoorthy S, Cain DW, Xu X, Cook DN, Cidlowski JA. March 2019

Error-Prone Replication Through UV Lesions by DNA Polymerase Theta Protects Against Skin Cancers [Abstract Error-Prone Replication Through UV Lesions by DNA Polymerase Theta Protects Against Skin Cancers] [Synopsis Error-Prone Replication Through UV Lesions by DNA Polymerase Theta Protects Against Skin Cancers] Yoon JH, McArthur MJ, Park J, Basu D, Wakamiya M, Prakash L, Prakash S. March 2019

Manganese Promotes the Aggregation and Prion-Like Cell-to-Cell Exosomal Transmission of Alpha-Synuclein [Abstract Manganese Promotes the Aggregation and Prion-Like Cell-to-Cell Exosomal Transmission of Alpha-Synuclein] [Synopsis Manganese Promotes the Aggregation and Prion-Like Cell-to-Cell Exosomal Transmission of Alpha-Synuclein] Harischandra DS, Rokad D, Neal ML, Ghaisas S, Manne S, Sarkar S, Panicker N, Zenitsky G, Jin H, Lewis M, Huang X, Anantharam V, Kanthasamy A, Kanthasamy AG. March 2019

Omega-3 and Omega-6 Intake Modifies Asthma Severity and Response to Indoor Air Pollution in Children [Abstract Omega-3 and Omega-6 Intake Modifies Asthma Severity and Response to Indoor Air Pollution in Children] [Synopsis Omega-3 and Omega-6 Intake Modifies Asthma Severity and Response to Indoor Air Pollution in Children] Brigham EP, Woo H, McCormack M, Rice J, Koehler K, Vulcain T, Wu T, Koch A, Sharma S, Kolahdooz F, Bose S, Hanson C, Romero K, Diette G, Hansel NN. March 2019

Phthalates and Phthalate Alternatives Have Diverse Associations With Oxidative Stress and Inflammation in Pregnant Women [Abstract Phthalates and Phthalate Alternatives Have Diverse Associations With Oxidative Stress and Inflammation in Pregnant Women] [Synopsis Phthalates and Phthalate Alternatives Have Diverse Associations With Oxidative Stress and Inflammation in Pregnant Women] van’t Erve TJ, Rosen EM, Barrett ES, Nguyen RHN, Sathyanarayana S, Milne GL, Calafat AM, Swan SH, Ferguson KK. March 2019

Ribosomal DNA Harbors An Evolutionary Conserved Clock of Biological Aging [Abstract Ribosomal DNA Harbors An Evolutionary Conserved Clock of Biological Aging] [Synopsis Ribosomal DNA Harbors An Evolutionary Conserved Clock of Biological Aging] Wang M, Lemos B. March 2019

Shift Work, DNA Methylation and Epigenetic Age [Abstract Shift Work, DNA Methylation and Epigenetic Age] [Synopsis Shift Work, DNA Methylation and Epigenetic Age] White AJ, Kresovich JK, Xu Z, Sandler DP, Taylor JA. March 2019

The Power of Resolution: Contextualized Understanding of Biological Responses to Liver Injury Chemicals Using High-throughput Transcriptomics and Benchmark Concentration Modeling [Abstract The Power of Resolution: Contextualized Understanding of Biological Responses to Liver Injury Chemicals Using High-throughput Transcriptomics and Benchmark Concentration Modeling] [Synopsis The Power of Resolution: Contextualized Understanding of Biological Responses to Liver Injury Chemicals Using High-throughput Transcriptomics and Benchmark Concentration Modeling] Ramaiahgari SC, Auerbach SS, Saddler TO, Rice JR, Dunlap PE, Sipes NS, DeVito MJ, Shah RR, Bushel PR, Merrick BA, Paules RS, Ferguson SS. March 2019

The Role of Dietary Phytoestrogens and the Nuclear Receptor PPARgamma in Adipogenesis: An In Vitro Study [Abstract The Role of Dietary Phytoestrogens and the Nuclear Receptor PPARgamma in Adipogenesis: An In Vitro Study] [Synopsis The Role of Dietary Phytoestrogens and the Nuclear Receptor PPARgamma in Adipogenesis: An In Vitro Study] Hall JM, Powell HA, Rajic L, Korach KS. March 2019

Using Tox21 High-Throughput Screening Assays for the Evaluation of Botanical and Dietary Supplements [Abstract Using Tox21 High-Throughput Screening Assays for the Evaluation of Botanical and Dietary Supplements] [Synopsis Using Tox21 High-Throughput Screening Assays for the Evaluation of Botanical and Dietary Supplements] Hubbard TD, Hsieh JH, Rider CV, Sipes NS, Sedykh A, Collins BJ, Auerbach SS, Xia M, Huang R, Walker NJ, DeVito MJ. March 2019

DDT and Breast Cancer: Prospective Study of Induction Time and Susceptibility Windows [Abstract DDT and Breast Cancer: Prospective Study of Induction Time and Susceptibility Windows] [Synopsis DDT and Breast Cancer: Prospective Study of Induction Time and Susceptibility Windows] Cohn BA, Cirillo PM, Terry MB. February 2019

Microcolony Size Distribution Assay Enables High-Throughput Cell Survival Quantitation [Abstract Microcolony Size Distribution Assay Enables High-Throughput Cell Survival Quantitation] [Synopsis Microcolony Size Distribution Assay Enables High-Throughput Cell Survival Quantitation] Ngo LP, Chan TK, Ge J, Samson LD, Engelward BP. February 2019

Repurposing Large Health Insurance Claims Data to Estimate Genetic and Environmental Contributions in 560 Phenotypes [Abstract Repurposing Large Health Insurance Claims Data to Estimate Genetic and Environmental Contributions in 560 Phenotypes] [Synopsis Repurposing Large Health Insurance Claims Data to Estimate Genetic and Environmental Contributions in 560 Phenotypes] Lakhani CM, Tierney BT, Manrai AK, Yang J, Visscher PM, Patel CJ. February 2019

SLC30A10 Transporter in the Digestive System Regulates Brain Manganese Under Basal Conditions While Brain SLC30A10 Protects Against Neurotoxity [Abstract SLC30A10 Transporter in the Digestive System Regulates Brain Manganese Under Basal Conditions While Brain SLC30A10 Protects Against Neurotoxity] [Synopsis SLC30A10 Transporter in the Digestive System Regulates Brain Manganese Under Basal Conditions While Brain SLC30A10 Protects Against Neurotoxity] Taylor CA, Hutchens S, Liu C, Jursa T, Shawlot W, Aschner M, Smith DR, Mukhopadhyay S. February 2019

Still Moving Toward Automation of the Systematic Review Process: A Summary of Discussions at the Third Meeting of the International Collaboration for Automation of Systematic Reviews (ICASR) [Abstract Still Moving Toward Automation of the Systematic Review Process: A Summary of Discussions at the Third Meeting of the International Collaboration for Automation of Systematic Reviews (ICASR)] [Synopsis Still Moving Toward Automation of the Systematic Review Process: A Summary of Discussions at the Third Meeting of the International Collaboration for Automation of Systematic Reviews (ICASR)] O’Connor AM, Tsafnat G, Gilbert SB, Thayer KA, Shemilt I, Thomas J, Glasziou P, Wolfe MS. February 2019

A Guardian Residue Hinders Insertion of a Fapy-dGTP Analog by Modulating the Open-Closed DNA Polymerase Transition [Abstract A Guardian Residue Hinders Insertion of a Fapy-dGTP Analog by Modulating the Open-Closed DNA Polymerase Transition] [Synopsis A Guardian Residue Hinders Insertion of a Fapy-dGTP Analog by Modulating the Open-Closed DNA Polymerase Transition] Smith MR, Shock DD, Beard WA, Greenberg MM, Freudenthal BD, Wilson SH. January 2019

Association of Phthalates, Parabens and Phenols Found In Personal Care Products With Pubertal Timing In Girls and Boys [Abstract Association of Phthalates, Parabens and Phenols Found In Personal Care Products With Pubertal Timing In Girls and Boys] [Synopsis Association of Phthalates, Parabens and Phenols Found In Personal Care Products With Pubertal Timing In Girls and Boys] [Story Association of Phthalates, Parabens and Phenols Found In Personal Care Products With Pubertal Timing In Girls and Boys] Harley KG, Berger KP, Kogut K, Parra K, Lustig RH, Greenspan LC, Calafat AM, Ye X, Eskenazi B. January 2019

Cryo-EM Structure of the Essential Ribosome Assembly AAA-ATPase Rix7 [Abstract Cryo-EM Structure of the Essential Ribosome Assembly AAA-ATPase Rix7] [Synopsis Cryo-EM Structure of the Essential Ribosome Assembly AAA-ATPase Rix7] Lo YH, Sobhany M, Hsu AL, Ford BL, Krahn JM, Borgnia MJ, Stanley RE. January 2019

Development of an In-Home, Real-Time Air Pollutant Sensor Platform and Implications for Community Use [Abstract Development of an In-Home, Real-Time Air Pollutant Sensor Platform and Implications for Community Use] [Synopsis Development of an In-Home, Real-Time Air Pollutant Sensor Platform and Implications for Community Use] Gillooly SE, Zhou Y, Vallarino J, Chu MT, Michanowicz DR, Levy JI, Adamkiewicz G. January 2019

DNA Methylation in Mice is Influenced by Genetics As Well As Sex and Life Experience [Abstract DNA Methylation in Mice is Influenced by Genetics As Well As Sex and Life Experience] [Synopsis DNA Methylation in Mice is Influenced by Genetics As Well As Sex and Life Experience] Grimm SA, Shimbo T, Takaku M, Thomas JW, Auerbach S, Bennett BD, Bucher JR, Burkholder AB, Day F, Du Y, Duncan CG, French JE, Foley JF, Li J, Merrick BA, Tice RR, Wang T, Xu X, NISC Comparative Sequencing Program, Bushel PR, Fargo DC, Mullikin JC, Wade PA. January 2019

Screening for Developmental Neurotoxicity at the National Toxicology Program: The Future Is Here [Abstract Screening for Developmental Neurotoxicity at the National Toxicology Program: The Future Is Here] [Synopsis Screening for Developmental Neurotoxicity at the National Toxicology Program: The Future Is Here] Behl M, Ryan K, Hsieh JH, Parham F, Shapiro AJ, Collins BJ, Sipes NS, Birnbaum LS, Bucher JR, Foster PMD, Walker NJ, Paules RS, Tice RR. January 2019

The Absence of the Catalytic Domains of Saccharomyces cerevisiae DNA Polymerase Epsilon Strongly Reduces DNA Replication Fidelity [Abstract The Absence of the Catalytic Domains of Saccharomyces cerevisiae DNA Polymerase Epsilon Strongly Reduces DNA Replication Fidelity] [Synopsis The Absence of the Catalytic Domains of Saccharomyces cerevisiae DNA Polymerase Epsilon Strongly Reduces DNA Replication Fidelity] Garbacz MA, Cox PB, Sharma S, Lujan SA, Chabes A, Kunkel TA. January 2019

The Relationship Between Progesterone, Sleep, and LH and FSH Secretory Dynamics in Early Post-Menarchal Girls [Abstract The Relationship Between Progesterone, Sleep, and LH and FSH Secretory Dynamics in Early Post-Menarchal Girls] [Synopsis The Relationship Between Progesterone, Sleep, and LH and FSH Secretory Dynamics in Early Post-Menarchal Girls] Sun BZ, Kangarloo T, Adams JM, Sluss P, Chandler DW, Zava DT, McGrath JA, Umbach DM, Shaw ND. January 2019

Association Between Residential Greenness and Cardiovascular Disease Risk [Abstract Association Between Residential Greenness and Cardiovascular Disease Risk] [Synopsis Association Between Residential Greenness and Cardiovascular Disease Risk] [Story Association Between Residential Greenness and Cardiovascular Disease Risk] Yeager R, Riggs DW, DeJarnett N, Tollerud DJ, Wilson J, Conklin DJ, O’Toole TE, McCracken J, Lorkiewicz P, Xie Z, Zafar N, Krishnasamy SS, Srivastava S, Finch J, Keith RJ, DeFilippis A, Rai SN, Liu G, Bhatnagar A. December 2018

Associations Between School Lunch Consumption and Urinary Phthalate Metabolite Concentrations in U.S. Children and Adolescents: Results from NHANES 2003-2014 [Abstract Associations Between School Lunch Consumption and Urinary Phthalate Metabolite Concentrations in U.S. Children and Adolescents: Results from NHANES 2003-2014] [Synopsis Associations Between School Lunch Consumption and Urinary Phthalate Metabolite Concentrations in U.S. Children and Adolescents: Results from NHANES 2003-2014] Munoz I, Colacino JA, Lewis RC, Arthur AE, Meeker JD, Ferguson KK. December 2018

Cardiovascular Disease Hospitalizations in Louisiana Parishes’ Elderly Before, During and After Hurricane Katrina [Abstract Cardiovascular Disease Hospitalizations in Louisiana Parishes’ Elderly Before, During and After Hurricane Katrina] [Synopsis Cardiovascular Disease Hospitalizations in Louisiana Parishes’ Elderly Before, During and After Hurricane Katrina] Becquart NA, Naumova EN, Singh G, Chui KKH. December 2018

Dentine Biomarkers of Prenatal and Early Childhood Exposure To Manganese, Zinc and Lead and Childhood Behavior [Abstract Dentine Biomarkers of Prenatal and Early Childhood Exposure To Manganese, Zinc and Lead and Childhood Behavior] [Synopsis Dentine Biomarkers of Prenatal and Early Childhood Exposure To Manganese, Zinc and Lead and Childhood Behavior] Horton MK, Hsu L, Claus Henn B, Margolis A, Austin C, Svensson K, Schnaas L, Gennings C, Hu H, Wright R, Rojo MMT, Arora M. December 2018

Epigenome-Wide Meta-Analysis of DNA Methylation and Childhood Asthma [Abstract Epigenome-Wide Meta-Analysis of DNA Methylation and Childhood Asthma] [Synopsis Epigenome-Wide Meta-Analysis of DNA Methylation and Childhood Asthma] Reese SE, Xu CJ, den Dekker HT, Lee MK, Sikdar S, Ruiz-Arenas C, et al.. December 2018

Greatly Enhanced Removal of Volatile Organic Carcinogens by a Genetically Modified Houseplant, Pothos Ivy (Epipremnum aureum) Expressing the Mammalian Cytochrome P450 2e1 Gene [Abstract Greatly Enhanced Removal of Volatile Organic Carcinogens by a Genetically Modified Houseplant, Pothos Ivy (Epipremnum aureum) Expressing the Mammalian Cytochrome P450 2e1 Gene] [Synopsis Greatly Enhanced Removal of Volatile Organic Carcinogens by a Genetically Modified Houseplant, Pothos Ivy (Epipremnum aureum) Expressing the Mammalian Cytochrome P450 2e1 Gene] Zhang L, Routsong R, Strand SE. December 2018

Impact of In Vitro Heavy Metal Exposure On Pancreatic Beta-Cell Function [Abstract Impact of In Vitro Heavy Metal Exposure On Pancreatic Beta-Cell Function] [Synopsis Impact of In Vitro Heavy Metal Exposure On Pancreatic Beta-Cell Function] Dover EN, Patel NY, Styblo M. December 2018

N-Terminal Transactivation Function, AF-1, of Estrogen Receptor Alpha Controls Obesity Through Enhancement of Energy Expenditure [Abstract N-Terminal Transactivation Function, AF-1, of Estrogen Receptor Alpha Controls Obesity Through Enhancement of Energy Expenditure] [Synopsis N-Terminal Transactivation Function, AF-1, of Estrogen Receptor Alpha Controls Obesity Through Enhancement of Energy Expenditure] Arao Y, Hamilton KJ, Lierz SL, Korach KS. December 2018

Prenatal Fluoride Exposure and Attention Deficit Hyperactivity Disorder (ADHD) Symptoms in Children at 6-12 Years of Age in Mexico City [Abstract Prenatal Fluoride Exposure and Attention Deficit Hyperactivity Disorder (ADHD) Symptoms in Children at 6-12 Years of Age in Mexico City] [Synopsis Prenatal Fluoride Exposure and Attention Deficit Hyperactivity Disorder (ADHD) Symptoms in Children at 6-12 Years of Age in Mexico City] Bashash M, Marchand M, Hu H, Till C, Martinez-Mier EA, Sanchez BN, Basu N, Peterson KE, Green R, Schnaas L, Mercado-Garcia A, Hernandez-Avila M, Tellez-Rojo MM. December 2018

Sinus Surgery is Associated With a Decrease in Aspirin-Induced Reaction Severity in Patients With Aspirin Exacerbated Respiratory Disease [Abstract Sinus Surgery is Associated With a Decrease in Aspirin-Induced Reaction Severity in Patients With Aspirin Exacerbated Respiratory Disease] [Synopsis Sinus Surgery is Associated With a Decrease in Aspirin-Induced Reaction Severity in Patients With Aspirin Exacerbated Respiratory Disease] Jerschow E, Edin ML, Chi Y, Hurst B, Abuzeid WM, Akbar NA, Gibber M, Fried MP, Han W, Pelletier T, Ren Z, Keskin T, Gottlieb GR, Lih FB, Gruzdev A, Bradbury JA, Schuster V, Spivack S, Rosenstreich D, Zeldin DC. December 2018

Tetrabromobisphenol-A Promotes Early Adipogenesis and Lipogenesis in 3T3-L1 Cells [Abstract Tetrabromobisphenol-A Promotes Early Adipogenesis and Lipogenesis in 3T3-L1 Cells] [Synopsis Tetrabromobisphenol-A Promotes Early Adipogenesis and Lipogenesis in 3T3-L1 Cells] Chappell VA, Janesick A, Blumberg B, Fenton SE. December 2018

The Gut Microbiome is Required For Full Protection Against Acute Arsenic Toxicity in Mouse Models [Abstract The Gut Microbiome is Required For Full Protection Against Acute Arsenic Toxicity in Mouse Models] [Synopsis The Gut Microbiome is Required For Full Protection Against Acute Arsenic Toxicity in Mouse Models] Coryell M, McAlpine M, Pinkham NV, McDermott TR, Walk ST. December 2018

Urinary Trace Metals Individually and in Mixtures in Association with Preterm Birth [Abstract Urinary Trace Metals Individually and in Mixtures in Association with Preterm Birth] [Synopsis Urinary Trace Metals Individually and in Mixtures in Association with Preterm Birth] Kim SS, Meeker JD, Carroll R, Zhao S, Mourgas MJ, Richard MJ, Aung M, Cantonwine DE, McElrath TF, Ferguson KK. December 2018

CA2 Neuronal Activity Controls Hippocampal Low Gamma and Ripple Oscillations [Abstract CA2 Neuronal Activity Controls Hippocampal Low Gamma and Ripple Oscillations] [Synopsis CA2 Neuronal Activity Controls Hippocampal Low Gamma and Ripple Oscillations] Alexander GM, Brown LY, Farris S, Lustberg D, Pantazis C, Gloss B, Plummer NW, Jensen P, Dudek SM. November 2018

Epigenetic Enzymes, Age, and Ancestry Regulate the Efficiency of Human iPSC Reprogramming [Abstract Epigenetic Enzymes, Age, and Ancestry Regulate the Efficiency of Human iPSC Reprogramming] [Synopsis Epigenetic Enzymes, Age, and Ancestry Regulate the Efficiency of Human iPSC Reprogramming] Mackey LC, Annab LA, Yang J, Rao B, Kissling GE, Schurman SH, Dixon D, Archer TK. November 2018

Histone Tails Decrease N7-methyl-2’-deoxyguanosine Depurination and Yield DNA-Protein-Cross-Links in Nucleosome Core Particles and Cells [Abstract Histone Tails Decrease N7-methyl-2’-deoxyguanosine Depurination and Yield DNA-Protein-Cross-Links in Nucleosome Core Particles and Cells] [Synopsis Histone Tails Decrease N7-methyl-2’-deoxyguanosine Depurination and Yield DNA-Protein-Cross-Links in Nucleosome Core Particles and Cells] Yang K, Park D, Tretyakova NY, Greenberg MM. November 2018

Intrauterine Multi-Metal Exposure is Associated With Reduced Fetal Growth Through Modulation of the Placental Gene Network [Abstract Intrauterine Multi-Metal Exposure is Associated With Reduced Fetal Growth Through Modulation of the Placental Gene Network] [Synopsis Intrauterine Multi-Metal Exposure is Associated With Reduced Fetal Growth Through Modulation of the Placental Gene Network] Deyssenroth MA, Gennings C, Liu SH, Peng S, Hao K, Lambertini L, Jackson BP, Karagas MR, Marsit CJ. November 2018

Signaling Events Downstream of AHR Activation That Contribute to Toxic Responses: The Functional Role of an AHR-Dependent Long Noncoding RNA (slincR) Using the Zebrafish Model [Abstract Signaling Events Downstream of AHR Activation That Contribute to Toxic Responses: The Functional Role of an AHR-Dependent Long Noncoding RNA (slincR) Using the Zebrafish Model] [Synopsis Signaling Events Downstream of AHR Activation That Contribute to Toxic Responses: The Functional Role of an AHR-Dependent Long Noncoding RNA (slincR) Using the Zebrafish Model] Garcia GR, Shankar P, Dunham CL, Garcia A, La Du JK, Truong L, Tilton SC, Tanguay RL. November 2018

Single-Molecule DREEM Imaging Reveals DNA Wrapping Around Human Mitochondrial Single-Stranded DNA Binding Protein [Abstract Single-Molecule DREEM Imaging Reveals DNA Wrapping Around Human Mitochondrial Single-Stranded DNA Binding Protein] [Synopsis Single-Molecule DREEM Imaging Reveals DNA Wrapping Around Human Mitochondrial Single-Stranded DNA Binding Protein] Kaur P, Longley MJ, Pan H, Wang H, Copeland WC. November 2018

A Distinct Class of Antioxidant Response Elements is Consistently Activated in Tumors With NRF2 Mutations [Abstract A Distinct Class of Antioxidant Response Elements is Consistently Activated in Tumors With NRF2 Mutations] [Synopsis A Distinct Class of Antioxidant Response Elements is Consistently Activated in Tumors With NRF2 Mutations] Levings DC, Wang X, Kohlhase D, Bell DA, Slattery M. October 2018

Cholestenoic Acid is a Prognostic Biomarker in Acute Respiratory Distress Syndrome [Abstract Cholestenoic Acid is a Prognostic Biomarker in Acute Respiratory Distress Syndrome] [Synopsis Cholestenoic Acid is a Prognostic Biomarker in Acute Respiratory Distress Syndrome] Madenspacher JH, Stapleton RD, Suratt BT, Dixon AE, Lih FB, Lowe JM, Mould KJ, Janssen WJ, Morrell ED, Wurfel MM, Garantziotis S, Tomer KB, Fessler MB. October 2018

Metformin Targets Mitochondrial Electron Transport to Reduce Air-Pollution-Induced Thrombosis [Abstract Metformin Targets Mitochondrial Electron Transport to Reduce Air-Pollution-Induced Thrombosis] [Synopsis Metformin Targets Mitochondrial Electron Transport to Reduce Air-Pollution-Induced Thrombosis] Soberanes S, Misharin AV, Jairaman A, Morales-Nebreda L, McQuattie-Pimentel AC, Cho T, Hamanaka RB, Meliton AY, Reyfman PA, Walter JM, Chen CI, Chi M, Chiu S, Gonzalez-Gonzalez FJ, Antalek M, Abdala-Valencia H, Chiarella SE, Sun KA, Woods PS, Ghio AJ, Jain M, Perlman H, Ridge KM, Morimoto RI, Sznajder JI, Balch WE, Bhorade SM, Bharat A, Prakriya M, Chandel NS, Mutlu GM, Budinger GRS. October 2018

Multi-Generational Impacts of Arsenic Exposure On Genome-Wide DNA Methylation and the Implications For Arsenic-Induced Skin Lesions [Abstract Multi-Generational Impacts of Arsenic Exposure On Genome-Wide DNA Methylation and the Implications For Arsenic-Induced Skin Lesions] [Synopsis Multi-Generational Impacts of Arsenic Exposure On Genome-Wide DNA Methylation and the Implications For Arsenic-Induced Skin Lesions] Guo X, Chen X, Wang J, Liu Z, Gaile D, Wu H, Yu G, Mao G, Yang Z, Di Z, Guo X, Cao L, Change P, Kang B, Chen J, Gao W, Ren X. October 2018

Pol Mu dGTP Mismatch Insertion Opposite T Coupled With Ligation Reveals Promutagenic DNA Repair Intermediate [Abstract Pol Mu dGTP Mismatch Insertion Opposite T Coupled With Ligation Reveals Promutagenic DNA Repair Intermediate] [Synopsis Pol Mu dGTP Mismatch Insertion Opposite T Coupled With Ligation Reveals Promutagenic DNA Repair Intermediate] Caglayan M, Wilson SH. October 2018

SOX17 Regulates Uterine Epithelial-Stromal Cross-Talk Acting Via a Distal Enhancer Upstream of IHH [Abstract SOX17 Regulates Uterine Epithelial-Stromal Cross-Talk Acting Via a Distal Enhancer Upstream of IHH] [Synopsis SOX17 Regulates Uterine Epithelial-Stromal Cross-Talk Acting Via a Distal Enhancer Upstream of IHH] [Story SOX17 Regulates Uterine Epithelial-Stromal Cross-Talk Acting Via a Distal Enhancer Upstream of IHH] Wang X, Li X, Wang T, Wu SP, Jeong JW, Kim TH, Young SL, Lessey BA, Lanz RB, Lydon JP, DeMayo FJ. October 2018

The Impact of Heat and Impaired Kidney Function On Productivity of Guatemalan Sugarcane Workers [Abstract The Impact of Heat and Impaired Kidney Function On Productivity of Guatemalan Sugarcane Workers] [Synopsis The Impact of Heat and Impaired Kidney Function On Productivity of Guatemalan Sugarcane Workers] Dally M, Butler-Dawson J, Krisher L, Monaghan A, Weitzenkamp D, Sorensen C, Johnson RJ, Carlton EJ, Ascensio C, Tenney L, Newman LS. October 2018

TRPM7 and CaV3.2 Channels Mediate Ca2plus Influx Required for Egg Activation at Fertilization [Abstract TRPM7 and CaV3.2 Channels Mediate Ca2plus Influx Required for Egg Activation at Fertilization] [Synopsis TRPM7 and CaV3.2 Channels Mediate Ca2plus Influx Required for Egg Activation at Fertilization] Bernhardt ML, Stein P, Carvacho I, Krapp C, Ardestani G, Mehregan A, Umbach DM, Bartolomei MS, Fissore RA, Williams CJ. October 2018

Arsenic Alters Exosome Quantity and Cargo to Mediate Stem Cell Recruitment Into a Cancer Stem Cell-Like Phenotype [Abstract Arsenic Alters Exosome Quantity and Cargo to Mediate Stem Cell Recruitment Into a Cancer Stem Cell-Like Phenotype] [Synopsis Arsenic Alters Exosome Quantity and Cargo to Mediate Stem Cell Recruitment Into a Cancer Stem Cell-Like Phenotype] Ngalame NNO, Luz AL, Makia N, Tokar EJ. September 2018

Biosynthesis of the Neurotoxin Domoic Acid in a Bloom-Forming Diatom [Abstract Biosynthesis of the Neurotoxin Domoic Acid in a Bloom-Forming Diatom] [Synopsis Biosynthesis of the Neurotoxin Domoic Acid in a Bloom-Forming Diatom] Brunson JK, McKinnie SMK, Chekan JR, McCrow JP, Miles ZD, Bertrand EM, Bielinski VA, Luhavaya H, Obornik M, Smith GJ, Hutchins DA, Allen AE, Moore BS. September 2018

ER Stress Drives Lipogenesis and Steatohepatitis Via Caspase-2 Activation of S1P [Abstract ER Stress Drives Lipogenesis and Steatohepatitis Via Caspase-2 Activation of S1P] [Synopsis ER Stress Drives Lipogenesis and Steatohepatitis Via Caspase-2 Activation of S1P] Kim JY, Garcia-Carbonell R, Yamachika S, Zhao P, Dhar D, Loomba R, Kaufman RJ, Saltiel AR, Karin M. September 2018

Genome-Wide Identification of FOXL2 Binding and Characterization of FOXL2 Feminizing Action in the Fetal Gonads [Abstract Genome-Wide Identification of FOXL2 Binding and Characterization of FOXL2 Feminizing Action in the Fetal Gonads] [Synopsis Genome-Wide Identification of FOXL2 Binding and Characterization of FOXL2 Feminizing Action in the Fetal Gonads] [Story Genome-Wide Identification of FOXL2 Binding and Characterization of FOXL2 Feminizing Action in the Fetal Gonads] Nicol B, Grimm SA, Gruzdev A, Scott G, Ray MK, Yao HH. September 2018

Revealing a Human p53 Universe [Abstract Revealing a Human p53 Universe] [Synopsis Revealing a Human p53 Universe] [Story Revealing a Human p53 Universe] Nguyen TT, Grimm SA, Bushel PR, Li J, Li Y, Bennet BD, Lavender CA, Ward JM, Fargo DC, Anderson CW, Li L, Resnick MA, Menendez D. September 2018

Sources of Clinically Significant Neonatal Intensive Care Unit Phthalate Exposure [Abstract Sources of Clinically Significant Neonatal Intensive Care Unit Phthalate Exposure] [Synopsis Sources of Clinically Significant Neonatal Intensive Care Unit Phthalate Exposure] Stroustrup A, Bragg JB, Busgang SA, Andra SS, Curtin P, Spear EA, Just AC, Arora M, Gennings C. September 2018

Association of Maternal Insecticide Levels With Autism In Offspring From a National Birth Cohort [Abstract Association of Maternal Insecticide Levels With Autism In Offspring From a National Birth Cohort] [Synopsis Association of Maternal Insecticide Levels With Autism In Offspring From a National Birth Cohort] Brown AS, Cheslack-Postava K, Rantakokko P, Kiviranta H, Hinkka-Yli-Salomaki S, McKeague IW, Surcel HM, Sourander A. August 2018

Bone Lead Levels and Risk of Incident Primary Open-Angle Glaucoma: The VA Normative Aging Study [Abstract Bone Lead Levels and Risk of Incident Primary Open-Angle Glaucoma: The VA Normative Aging Study] [Synopsis Bone Lead Levels and Risk of Incident Primary Open-Angle Glaucoma: The VA Normative Aging Study] Wang W, Moroi S, Bakulski K, Mukherjee B, Weisskopf MG, Schaumberg D, Sparrow D, Vokonas PS, Hu H, Park SK. August 2018

Exome Sequencing of Fresh-frozen or Formalin-fixed Paraffin-embedded B6C3F1/N Mouse Hepatocellular Carcinomas Arising Either Spontaneously or Due to Chronic Chemical Exposure [Abstract Exome Sequencing of Fresh-frozen or Formalin-fixed Paraffin-embedded B6C3F1/N Mouse Hepatocellular Carcinomas Arising Either Spontaneously or Due to Chronic Chemical Exposure] [Synopsis Exome Sequencing of Fresh-frozen or Formalin-fixed Paraffin-embedded B6C3F1/N Mouse Hepatocellular Carcinomas Arising Either Spontaneously or Due to Chronic Chemical Exposure] Auerbach SS, Xu M, Merrick BA, Hoenerhoff MJ, Phadke D, Taxman DJ, Shah R, Hong HL, Ton TV, Kovi RC, Sills RC, Pandiri AR. August 2018

Follow That Botanical: Challenges and Recommendations For Assessing Absorption, Distribution, Metabolism and Excretion of Botanical Dietary Supplements [Abstract Follow That Botanical: Challenges and Recommendations For Assessing Absorption, Distribution, Metabolism and Excretion of Botanical Dietary Supplements] [Synopsis Follow That Botanical: Challenges and Recommendations For Assessing Absorption, Distribution, Metabolism and Excretion of Botanical Dietary Supplements] Waidyanatha S, Ryan K, Roe AL, Jia W, Paine MF, Ferguson S, Gurley BJ, Welch K, Chow MSS, Devito M, Rider C. August 2018

Hexavalent Chromium-Induced Chromosome Instability Drives Permanent and Heritable Numerical and Structural Changes and a DNA Repair-Deficient Phenotype [Abstract Hexavalent Chromium-Induced Chromosome Instability Drives Permanent and Heritable Numerical and Structural Changes and a DNA Repair-Deficient Phenotype] [Synopsis Hexavalent Chromium-Induced Chromosome Instability Drives Permanent and Heritable Numerical and Structural Changes and a DNA Repair-Deficient Phenotype] Wise SS, Aboueissa AE, Martino J, Wise JP Sr. August 2018

Nuclear Receptor CAR Suppresses GADD45B-p38 MAPK Signaling to Promote Phenobarbital-Induced Proliferation In Mouse Liver [Abstract Nuclear Receptor CAR Suppresses GADD45B-p38 MAPK Signaling to Promote Phenobarbital-Induced Proliferation In Mouse Liver] [Synopsis Nuclear Receptor CAR Suppresses GADD45B-p38 MAPK Signaling to Promote Phenobarbital-Induced Proliferation In Mouse Liver] Hori T, Saito K, Moore R, Flake GP, Negishi M. August 2018

Sex-Specific Associations Of Infants’ Gut Microbiome With Arsenic Exposure In a U.S. Population [Abstract Sex-Specific Associations Of Infants’ Gut Microbiome With Arsenic Exposure In a U.S. Population] [Synopsis Sex-Specific Associations Of Infants’ Gut Microbiome With Arsenic Exposure In a U.S. Population] Hoen AG, Madan JC, Li Z, Coker M, Lundgren SN, Morrison HG, Palys T, Jackson BP, Sogin ML, Cottingham KL, Karagas MR. August 2018

Toll-like Receptor 4 Pathway Polymorphisms Interact with Pollution to Influence Asthma Diagnosis and Severity [Abstract Toll-like Receptor 4 Pathway Polymorphisms Interact with Pollution to Influence Asthma Diagnosis and Severity] [Synopsis Toll-like Receptor 4 Pathway Polymorphisms Interact with Pollution to Influence Asthma Diagnosis and Severity] [Story Toll-like Receptor 4 Pathway Polymorphisms Interact with Pollution to Influence Asthma Diagnosis and Severity] Schurman SH, Bravo MA, Innes CL, Jackson WB 2nd, McGrath JA, Miranda ML, Garantziotis S. August 2018

Air-Quality-Related Health Impacts From Climate Change and From Adaptation of Cooling Demand for Buildings in the Eastern United States: An Interdisciplinary Modeling Study [Abstract Air-Quality-Related Health Impacts From Climate Change and From Adaptation of Cooling Demand for Buildings in the Eastern United States: An Interdisciplinary Modeling Study] [Synopsis Air-Quality-Related Health Impacts From Climate Change and From Adaptation of Cooling Demand for Buildings in the Eastern United States: An Interdisciplinary Modeling Study] Abel DW, Holloway T, Harkey M, Meier P, Ahl D, Limaye VS, Patz JA. July 2018

Association of Exposure to Diethylstilbestrol During Pregnancy With Multigenerational Neurodevelopmental Deficits [Abstract Association of Exposure to Diethylstilbestrol During Pregnancy With Multigenerational Neurodevelopmental Deficits] [Synopsis Association of Exposure to Diethylstilbestrol During Pregnancy With Multigenerational Neurodevelopmental Deficits] Kioumourtzoglou MA, Coull BA, O’Reilly EJ, Ascherio A, Weisskopf MG. July 2018

Disposition and Metabolism of the Bisphenol Analogue, Bisphenol S, in Harlan Sprague Dawley Rats and B6C3F1/N Mice and In Vitro in Hepatocytes From Rats, Mice, and Humans [Abstract Disposition and Metabolism of the Bisphenol Analogue, Bisphenol S, in Harlan Sprague Dawley Rats and B6C3F1/N Mice and In Vitro in Hepatocytes From Rats, Mice, and Humans] [Synopsis Disposition and Metabolism of the Bisphenol Analogue, Bisphenol S, in Harlan Sprague Dawley Rats and B6C3F1/N Mice and In Vitro in Hepatocytes From Rats, Mice, and Humans] Waidyanatha S, Black SR, Snyder RW, Yueh YL, Sutherland V, Patel PR, Watson SL, Fennell TR. July 2018

Mechanism of APTX Nicked DNA Sensing and Pleiotropic Inactivation in Neurodegenerative Disease [Abstract Mechanism of APTX Nicked DNA Sensing and Pleiotropic Inactivation in Neurodegenerative Disease] [Synopsis Mechanism of APTX Nicked DNA Sensing and Pleiotropic Inactivation in Neurodegenerative Disease] [Story Mechanism of APTX Nicked DNA Sensing and Pleiotropic Inactivation in Neurodegenerative Disease] Tumbale P, Schellenberg MJ, Mueller GA, Fairweather E, Watson M, Little JN, Krahn J, Waddell I, London RE, Williams RS. July 2018

Perinatal Exposure To An Environmentally Relevant Mixture of Phthalates Results In a Lower Number of Neurons and Synapses in the Medial Prefrontal Cortex and Decreased Cognitive Flexibility in Adult Male and Female Rats [Abstract Perinatal Exposure To An Environmentally Relevant Mixture of Phthalates Results In a Lower Number of Neurons and Synapses in the Medial Prefrontal Cortex and Decreased Cognitive Flexibility in Adult Male and Female Rats] [Synopsis Perinatal Exposure To An Environmentally Relevant Mixture of Phthalates Results In a Lower Number of Neurons and Synapses in the Medial Prefrontal Cortex and Decreased Cognitive Flexibility in Adult Male and Female Rats] Kougias DG, Sellinger EP, Willing J, Juraska JM. July 2018

Separation of Circadian- and Behavior-driven Metabolite Rhythms in Humans Provides a Window on Peripheral Oscillators and Metabolism [Abstract Separation of Circadian- and Behavior-driven Metabolite Rhythms in Humans Provides a Window on Peripheral Oscillators and Metabolism] [Synopsis Separation of Circadian- and Behavior-driven Metabolite Rhythms in Humans Provides a Window on Peripheral Oscillators and Metabolism] Skene DJ, Skornyakov E, Chowdhury NR, Gajula RP, Middleton B, Satterfield BC, Porter KI, Van Dongen HPA, Gaddameedhi S. July 2018

Structures of DNA-bound Human Ligase IV Catalytic Core Reveal Insights Into Substrate Binding and Catalysis [Abstract Structures of DNA-bound Human Ligase IV Catalytic Core Reveal Insights Into Substrate Binding and Catalysis] [Synopsis Structures of DNA-bound Human Ligase IV Catalytic Core Reveal Insights Into Substrate Binding and Catalysis] Kaminski AM, Tumbale PP, Schellenberg MJ, Williams RS, Williams JG, Kunkel TA, Pedersen LC, Bebenek K. July 2018

Developmental Exposure To a Mixture of 23 Chemicals Associated With Unconventional Oil and Gas Operations Alters the Immune System of Mice [Abstract Developmental Exposure To a Mixture of 23 Chemicals Associated With Unconventional Oil and Gas Operations Alters the Immune System of Mice] [Synopsis Developmental Exposure To a Mixture of 23 Chemicals Associated With Unconventional Oil and Gas Operations Alters the Immune System of Mice] Boule LA, Chapman TJ, Hillman SE, Kassotis CD, O’Dell C, Robert J, Georas SN, Nagel SC, Lawrence BP. June 2018

Elucidating Gene-By-Environment Interactions Associated with Differential Susceptibility to Chemical Exposure [Abstract Elucidating Gene-By-Environment Interactions Associated with Differential Susceptibility to Chemical Exposure] [Synopsis Elucidating Gene-By-Environment Interactions Associated with Differential Susceptibility to Chemical Exposure] Balik-Meisner M, Truong L, Scholl EH, La Du JK, Tanguay RL, Reif DM. June 2018

Liver Cancer Initiation Requires p53 Inhibition by CD44-Enhanced Growth Factor Signaling [Abstract Liver Cancer Initiation Requires p53 Inhibition by CD44-Enhanced Growth Factor Signaling] [Synopsis Liver Cancer Initiation Requires p53 Inhibition by CD44-Enhanced Growth Factor Signaling] Dhar D, Antonucci L, Nakagawa H, Kim JY, Glitzner E, Caruso S, Shalapour S, Yang L, Valasek MA, Lee S, Minnich K, Seki E, Tuckermann J, Sibilia M, Zucman-Rossi J, Karin M. June 2018

Maternal Polymorphisms in Glutathione-related Genes Are Associated With Maternal Mercury Concentrations and Early Child Neurodevelopment in a Population with a Fish-rich Diet [Abstract Maternal Polymorphisms in Glutathione-related Genes Are Associated With Maternal Mercury Concentrations and Early Child Neurodevelopment in a Population with a Fish-rich Diet] [Synopsis Maternal Polymorphisms in Glutathione-related Genes Are Associated With Maternal Mercury Concentrations and Early Child Neurodevelopment in a Population with a Fish-rich Diet] Wahlberg K, Love TM, Pineda D, Engstrom K, Watson GE, Thurston SW, Yeates AJ, Mulhern MS, McSorley EM, Strain JJ, Smith TH, Davidson PW, Shamlaye CF, Myers GJ, Rand MD, van Wijngaarden E, Broberg K. June 2018

Transitions in DNA Polymerase Beta Microsecond-Millisecond Dynamics Related to Substrate Binding and Catalysis [Abstract Transitions in DNA Polymerase Beta Microsecond-Millisecond Dynamics Related to Substrate Binding and Catalysis] [Synopsis Transitions in DNA Polymerase Beta Microsecond-Millisecond Dynamics Related to Substrate Binding and Catalysis] DeRose EF, Kirby TW, Mueller GA, Beard WA, Wilson SH, London RE. June 2018

Whole Exome Sequencing in the Rat [Abstract Whole Exome Sequencing in the Rat] [Synopsis Whole Exome Sequencing in the Rat] Foley JF, Phadke DP, Hardy O, Hardy S, Miller V, Madan A, Howard K, Kruse K, Lord C, Ramaiahgari S, Solomon GG, Shah RR, Pandiri AR, Herbert RA, Sills RC, Alex Merrick B. June 2018

BRG1 Governs Glucocorticoid Receptor Interactions With Chromatin and Pioneer Factors Across the Genome [Abstract BRG1 Governs Glucocorticoid Receptor Interactions With Chromatin and Pioneer Factors Across the Genome] [Synopsis BRG1 Governs Glucocorticoid Receptor Interactions With Chromatin and Pioneer Factors Across the Genome] Hoffman JA, Trotter KW, Ward JM, Archer TK. May 2018

Coal and Oil Power Plant Retirements in California Associated With Reduced Preterm Birth Among Populations Nearby [Abstract Coal and Oil Power Plant Retirements in California Associated With Reduced Preterm Birth Among Populations Nearby] [Synopsis Coal and Oil Power Plant Retirements in California Associated With Reduced Preterm Birth Among Populations Nearby] Casey JA, Karasek D, Ogburn EL, Goin DE, Dang K, Braveman PA, Morello-Frosch R. May 2018

Conditional Toxicity Value (CTV) Predictor: An In Silico Approach for Generating Quantitative Risk Estimates for Chemicals [Abstract Conditional Toxicity Value (CTV) Predictor: An In Silico Approach for Generating Quantitative Risk Estimates for Chemicals] [Synopsis Conditional Toxicity Value (CTV) Predictor: An In Silico Approach for Generating Quantitative Risk Estimates for Chemicals] Wignall JA, Muratov E, Sedykh A, Guyton KZ, Tropsha A, Rusyn I, Chiu WA. May 2018

Emissions of Tetrachlorobiphenyls (PCBs 47, 51, and 68) from Polymer Resin on Kitchen Cabinets as a Non-Aroclor Source to Residential Air [Abstract Emissions of Tetrachlorobiphenyls (PCBs 47, 51, and 68) from Polymer Resin on Kitchen Cabinets as a Non-Aroclor Source to Residential Air] [Synopsis Emissions of Tetrachlorobiphenyls (PCBs 47, 51, and 68) from Polymer Resin on Kitchen Cabinets as a Non-Aroclor Source to Residential Air] Herkert NJ, Jahnke JC, Hornbuckle KC. May 2018

EP300-Mediated Lysine 2-Hydroxyisobutyrylation Regulates Glycolysis [Abstract EP300-Mediated Lysine 2-Hydroxyisobutyrylation Regulates Glycolysis] [Synopsis EP300-Mediated Lysine 2-Hydroxyisobutyrylation Regulates Glycolysis] Huang H, Tang S, Ji M, Tang Z, Shimada M, Liu X, Qi S, Locasale JW, Roeder RG, Zhao Y, Li X. May 2018

Shared Epitope-Aryl Hydrocarbon Receptor Crosstalk Underlies the Mechanism of Gene-Environment Interaction in Autoimmune Arthritis [Abstract Shared Epitope-Aryl Hydrocarbon Receptor Crosstalk Underlies the Mechanism of Gene-Environment Interaction in Autoimmune Arthritis] [Synopsis Shared Epitope-Aryl Hydrocarbon Receptor Crosstalk Underlies the Mechanism of Gene-Environment Interaction in Autoimmune Arthritis] Fu J, Nogueira SV, Drongelen VV, Coit P, Ling S, Rosloniec EF, Sawalha AH, Holoshitz J. May 2018

Spectrally Resolved Fiber Photometry for Multi-Component Analysis of Brain Circuits [Abstract Spectrally Resolved Fiber Photometry for Multi-Component Analysis of Brain Circuits] [Synopsis Spectrally Resolved Fiber Photometry for Multi-Component Analysis of Brain Circuits] [Story Spectrally Resolved Fiber Photometry for Multi-Component Analysis of Brain Circuits] Meng C, Zhou J, Papaneri A, Peddada T, Xu K, Cui G. May 2018

Association Between Prenatal Exposure To Multiple Insecticides and Child Body Weight and Body Composition in the VHEMBE South African Birth Cohort [Abstract Association Between Prenatal Exposure To Multiple Insecticides and Child Body Weight and Body Composition in the VHEMBE South African Birth Cohort] [Synopsis Association Between Prenatal Exposure To Multiple Insecticides and Child Body Weight and Body Composition in the VHEMBE South African Birth Cohort] Coker E, Chevrier J, Rauch S, Bradman A, Obida M, Crause M, Bornman R, Eskenazi B. April 2018

Bias Amplification in Epidemiologic Analysis of Exposure to Mixtures [Abstract Bias Amplification in Epidemiologic Analysis of Exposure to Mixtures] [Synopsis Bias Amplification in Epidemiologic Analysis of Exposure to Mixtures] Weisskopf MG, Seals RM, Webster TF. April 2018

Identification of Smoking-Associated Differentially Methylated Regions Using Reduced Representation Bisulfite Sequencing and Cell type-Specific Enhancer Activation and Gene Expression [Abstract Identification of Smoking-Associated Differentially Methylated Regions Using Reduced Representation Bisulfite Sequencing and Cell type-Specific Enhancer Activation and Gene Expression] [Synopsis Identification of Smoking-Associated Differentially Methylated Regions Using Reduced Representation Bisulfite Sequencing and Cell type-Specific Enhancer Activation and Gene Expression] Wan M, Bennett BD, Pittman GS, Campbell MR, Reynolds LM, Porter DK, Crowl CL, Wang X, Su D, Englert NA, Thompson IJ, Liu Y, Bell DA. April 2018

Mitochondrial Nicotinamide Adenine Dinucleotide Reduced (NADH) Oxidation Links the Tricarboxylic Acid (TCA) Cycle With Methionine Metabolisms and Nuclear DNA Methylation [Abstract Mitochondrial Nicotinamide Adenine Dinucleotide Reduced (NADH) Oxidation Links the Tricarboxylic Acid (TCA) Cycle With Methionine Metabolisms and Nuclear DNA Methylation] [Synopsis Mitochondrial Nicotinamide Adenine Dinucleotide Reduced (NADH) Oxidation Links the Tricarboxylic Acid (TCA) Cycle With Methionine Metabolisms and Nuclear DNA Methylation] Lozoya OA, Martinez-Reyes I, Wang T, Grenet D, Bushel P, Li J, Chandel N, Woychik RP, Santos JH. April 2018

Naturally Complex: Perspectives and Challenges Associated With Botanical Dietary Supplement Safety Assessment [Abstract Naturally Complex: Perspectives and Challenges Associated With Botanical Dietary Supplement Safety Assessment] [Synopsis Naturally Complex: Perspectives and Challenges Associated With Botanical Dietary Supplement Safety Assessment] Shipkowski KA, Betz JM, Birnbaum LS, Bucher JR, Coates PM, Hopp DC, MacKay D, Oketch-Rabah H, Walker NJ, Welch C, Rider CV. April 2018

Neonatal Genistein Exposure and Glucocorticoid Signaling in the Adult Mouse Uterus [Abstract Neonatal Genistein Exposure and Glucocorticoid Signaling in the Adult Mouse Uterus] [Synopsis Neonatal Genistein Exposure and Glucocorticoid Signaling in the Adult Mouse Uterus] Whirledge SD, Kisanga EP, Oakley RH, Cidlowski JA. April 2018

Perinatal Bisphenol A Exposure Increases Atherosclerosis In Adult Male PXR-Humanized Mice [Abstract Perinatal Bisphenol A Exposure Increases Atherosclerosis In Adult Male PXR-Humanized Mice] [Synopsis Perinatal Bisphenol A Exposure Increases Atherosclerosis In Adult Male PXR-Humanized Mice] Sui Y, Park SH, Wang F, Zhou C. April 2018

Temporal Trends and Developmental Patterns of Plasma Polybrominated Diphenyl Ether Concentrations Over a 15-Year Period Between 1998 and 2013 [Abstract Temporal Trends and Developmental Patterns of Plasma Polybrominated Diphenyl Ether Concentrations Over a 15-Year Period Between 1998 and 2013] [Synopsis Temporal Trends and Developmental Patterns of Plasma Polybrominated Diphenyl Ether Concentrations Over a 15-Year Period Between 1998 and 2013] Cowell WJ, Sjodin A, Jones R, Wang Y, Wang s, Herbstman JB. April 2018

Toxicological Profiling of Metal Oxide Nanoparticles in Liver Context Reveals Pyroptosis in Kupffer Cells and Macrophages Versus Apoptosis in Hepatocytes [Abstract Toxicological Profiling of Metal Oxide Nanoparticles in Liver Context Reveals Pyroptosis in Kupffer Cells and Macrophages Versus Apoptosis in Hepatocytes] [Synopsis Toxicological Profiling of Metal Oxide Nanoparticles in Liver Context Reveals Pyroptosis in Kupffer Cells and Macrophages Versus Apoptosis in Hepatocytes] Mirshafiee V, Sun B, Chang CH, Liao YP, Jiang W, Jiang J, Liu X, Wang X, Xia T, Nel AE. April 2018

Widespread Enhancer Activation Via ER Alpha Mediates Estrogen Response In Vivo During Uterine Development [Abstract Widespread Enhancer Activation Via ER Alpha Mediates Estrogen Response In Vivo During Uterine Development] [Synopsis Widespread Enhancer Activation Via ER Alpha Mediates Estrogen Response In Vivo During Uterine Development] Jefferson WN, Kinyamu HK, Wang T, Miranda AX, Padilla-Banks E, Suen AA, Williams CJ. April 2018

Estrogen Deficiency Promotes Hepatic Steatosis Via a Glucocorticoid Receptor-Dependent Mechanism in Mice [Abstract Estrogen Deficiency Promotes Hepatic Steatosis Via a Glucocorticoid Receptor-Dependent Mechanism in Mice] [Synopsis Estrogen Deficiency Promotes Hepatic Steatosis Via a Glucocorticoid Receptor-Dependent Mechanism in Mice] Quinn MA, Xu X, Ronfani M, Cidlowski JA. March 2018

Exosomes From Asbestos-exposed Cells Modulate Gene Expression in Mesothelial Cells [Abstract Exosomes From Asbestos-exposed Cells Modulate Gene Expression in Mesothelial Cells] [Synopsis Exosomes From Asbestos-exposed Cells Modulate Gene Expression in Mesothelial Cells] Munson P, Lam YW, Dragon J, MacPherson M, Shukla A. March 2018

Human and Animal Evidence of Potential Transgenerational Inheritance of Health Effects: An Evidence Map and State-of-the-Science Evaluation [Abstract Human and Animal Evidence of Potential Transgenerational Inheritance of Health Effects: An Evidence Map and State-of-the-Science Evaluation] [Synopsis Human and Animal Evidence of Potential Transgenerational Inheritance of Health Effects: An Evidence Map and State-of-the-Science Evaluation] Walker VR, Boyles AL, Pelch KE, Holmgren SD, Shapiro AJ, Blystone CR, Devito MJ, Newbold RR, Blain R, Hartman P, Thayer KA. March 2018

Overexpression of the Base Excision Repair NTHL1 Glycosylase Causes Genomic Instability and Early Cellular Hallmarks of Cancer [Abstract Overexpression of the Base Excision Repair NTHL1 Glycosylase Causes Genomic Instability and Early Cellular Hallmarks of Cancer] [Synopsis Overexpression of the Base Excision Repair NTHL1 Glycosylase Causes Genomic Instability and Early Cellular Hallmarks of Cancer] Limpose KL, Trego KS, Li Z, Leung SW, Sarker AH, Shah JA, Ramalingam SS, Werner EM, Dynan WS, Cooper PK, Corbett AH, Doetsch PW. March 2018

Prenatal Exposure To Unconventional Oil and Gas Operation Chemical Mixtures Altered Mammary Gland Development in Adult Female Mice [Abstract Prenatal Exposure To Unconventional Oil and Gas Operation Chemical Mixtures Altered Mammary Gland Development in Adult Female Mice] [Synopsis Prenatal Exposure To Unconventional Oil and Gas Operation Chemical Mixtures Altered Mammary Gland Development in Adult Female Mice] Sapouckey SA, Kassotis CD, Nagel SC, Vandenberg LN. March 2018

A Hybrid Gene Selection Approach To Create the S1500+ Targeted Gene Sets For Use In High-Throughput Transcriptomics [Abstract A Hybrid Gene Selection Approach To Create the S1500+ Targeted Gene Sets For Use In High-Throughput Transcriptomics] [Synopsis A Hybrid Gene Selection Approach To Create the S1500+ Targeted Gene Sets For Use In High-Throughput Transcriptomics] Mav D, Shah RR, Howard BE, Auerbach SS, Bushel PR, Collins JB, Gerhold DL, Judson RS, Karmaus AL, Maull EA, Mendrick DL, Merrick BA, Sipes NS, Svoboda D, Paules RS. February 2018

Associations Between Personal Care Product Use Patterns and Breast Cancer Risk Among White and Black Women in the Sister Study [Abstract Associations Between Personal Care Product Use Patterns and Breast Cancer Risk Among White and Black Women in the Sister Study] [Synopsis Associations Between Personal Care Product Use Patterns and Breast Cancer Risk Among White and Black Women in the Sister Study] Taylor KW, Troester MA, Herring AH, Engel LS, Nichols HB, Sandler DP, Baird DD. February 2018

Characterization of the Molecular Crosstalk Within the Essential Grc3Las1 Pre-rRNA Processing Complex [Abstract Characterization of the Molecular Crosstalk Within the Essential Grc3Las1 Pre-rRNA Processing Complex] [Synopsis Characterization of the Molecular Crosstalk Within the Essential Grc3Las1 Pre-rRNA Processing Complex] Pillon MC, Sobhanhy M, Stanley RE. February 2018

EDC IMPACT: Molecular Effects of Developmental FM 550 Exposure in Wistar Rat Placenta and Fetal Forebrain [Abstract EDC IMPACT: Molecular Effects of Developmental FM 550 Exposure in Wistar Rat Placenta and Fetal Forebrain] [Synopsis EDC IMPACT: Molecular Effects of Developmental FM 550 Exposure in Wistar Rat Placenta and Fetal Forebrain] Rock KD, Horman B, Phillips AL, McRitchie SL, Watson S, Deese-Spruill J, Jima D, Sumner S, Stapleton HM, Patisaul HB. February 2018

Evidence That DNA Polymerase Delta Contributes To Initiating Leading Strand DNA Replication in Saccharomyces Cerevisiae [Abstract Evidence That DNA Polymerase Delta Contributes To Initiating Leading Strand DNA Replication in Saccharomyces Cerevisiae] [Synopsis Evidence That DNA Polymerase Delta Contributes To Initiating Leading Strand DNA Replication in Saccharomyces Cerevisiae] Garbacz MA, Lujan SA, Burkholder AB, Cox PB, Wu Q, Zhou ZX, Haber JE, Kunkel TA. February 2018

Perfluoroalkyl Substances and Changes In Body Weight and Resting Metabolic Rate In Response To Weight-Loss Diets: A Prospective Study [Abstract Perfluoroalkyl Substances and Changes In Body Weight and Resting Metabolic Rate In Response To Weight-Loss Diets: A Prospective Study] [Synopsis Perfluoroalkyl Substances and Changes In Body Weight and Resting Metabolic Rate In Response To Weight-Loss Diets: A Prospective Study] Liu G, Dhana K, Furtado JD, Rood J, Zong G, Liang L, Qi L, Bray GA, DeJonge L, Coull B, Grandjean P, Sun Q. February 2018

Periconception Exposure to Air Pollution and Risk of Congenital Malformations [Abstract Periconception Exposure to Air Pollution and Risk of Congenital Malformations] [Synopsis Periconception Exposure to Air Pollution and Risk of Congenital Malformations] Ren S, Haynes E, Hall E, Hossain M, Chen A, Muglia L, Lu L, DeFranco E. February 2018

An Obesity-Associated Gut Microbiome Reprograms the Intestinal Epigenome and Leads to Altered Colonic Gene Expression [Abstract An Obesity-Associated Gut Microbiome Reprograms the Intestinal Epigenome and Leads to Altered Colonic Gene Expression] [Synopsis An Obesity-Associated Gut Microbiome Reprograms the Intestinal Epigenome and Leads to Altered Colonic Gene Expression] Qin Y, Roberts JD, Grimm SA, Lih FB, Deterding LJ, Li R, Chrysovergis K, Wade PA. January 2018

Estrogen-Dependent Epigenetic Regulation of Soluble Epoxide Hydrolase Via DNA Methylation [Abstract Estrogen-Dependent Epigenetic Regulation of Soluble Epoxide Hydrolase Via DNA Methylation] [Synopsis Estrogen-Dependent Epigenetic Regulation of Soluble Epoxide Hydrolase Via DNA Methylation] Yang YM, Sun D, Kandhi S, Froogh G, Zhuge J, Huang W, Hammock BD, Huang A. January 2018

HAfTs Are Novel IncRNA Transcripts From Aflatoxin Exposure [Abstract HAfTs Are Novel IncRNA Transcripts From Aflatoxin Exposure] [Synopsis HAfTs Are Novel IncRNA Transcripts From Aflatoxin Exposure] Merrick BA, Chang JS, Phadke DP, Bostrom MA, Shah RR, Wang X, Gordon O, Wright GM. January 2018

Impact of Smoking Ban on Passive Smoke Exposure in Pregnant Non-Smokers in the Southeastern United States [Abstract Impact of Smoking Ban on Passive Smoke Exposure in Pregnant Non-Smokers in the Southeastern United States] [Synopsis Impact of Smoking Ban on Passive Smoke Exposure in Pregnant Non-Smokers in the Southeastern United States] Schechter JC, Fuemmeler BF, Hoyo C, Murphy SK, Zhang JJ, Kollins SH. January 2018

Labor-Management Cooperation in Illinois: How a Joint Union Company Team Is Improving Facility Safety [Abstract Labor-Management Cooperation in Illinois: How a Joint Union Company Team Is Improving Facility Safety] [Synopsis Labor-Management Cooperation in Illinois: How a Joint Union Company Team Is Improving Facility Safety] Mahan B, Maclin R, Ruttenberg R, Mundy K, Frazee T, Schwartzkopf R, Morawetz J. January 2018

Reducing the RNA Binding Protein TIA1 Protects Against Tau-Mediated Neurodegeneration In Vivo [Abstract Reducing the RNA Binding Protein TIA1 Protects Against Tau-Mediated Neurodegeneration In Vivo] [Synopsis Reducing the RNA Binding Protein TIA1 Protects Against Tau-Mediated Neurodegeneration In Vivo] Apicco DJ, Ash PEA, Maziuk B, LeBlang C, Medalla M, Al Abdullatif A, Ferragud A, Botelho E, Ballance HI, Dhawan U, Boudeau S, Cruz AL, Kashy D, Wong A, Goldberg LR, Yazdani N, Zhang C, Ung CY, Tripodis Y, Kanaan NM, Ikezu T, Cottone P, Leszyk J, Li H, Luebje K, Bryant CD, Wolozin B. January 2018

Ancestral Perinatal Obesogen Exposure Results in a Transgenerational Thrifty Phenotype in Mice [Abstract Ancestral Perinatal Obesogen Exposure Results in a Transgenerational Thrifty Phenotype in Mice] [Synopsis Ancestral Perinatal Obesogen Exposure Results in a Transgenerational Thrifty Phenotype in Mice] Chamorro-Garcia R, Diaz-Castillo C, Shoucri BM, Kach H, Leavitt R, Shioda T, Blumberg B. December 2017

Association of Short-term Exposure to Air Pollution With Mortality in Older Adults [Abstract Association of Short-term Exposure to Air Pollution With Mortality in Older Adults] [Synopsis Association of Short-term Exposure to Air Pollution With Mortality in Older Adults] Di Q, Dai L, Wang Y, Zanobetti A, Choirat C, Schwartz JD, Dominici F. December 2017

Characterization of the APLF FHA-XRCC1 Phosphopeptide Interaction and Its Structural and Functional Implications [Abstract Characterization of the APLF FHA-XRCC1 Phosphopeptide Interaction and Its Structural and Functional Implications] [Synopsis Characterization of the APLF FHA-XRCC1 Phosphopeptide Interaction and Its Structural and Functional Implications] Kim K, Pedersen LC, Kirby TW, DeRose EF, London RE. December 2017

Hippocampus and Entorhinal Cortex Recruit Cholinergic and NMDA Receptors Separately to Generate Hippocampal Theta Oscillations [Abstract Hippocampus and Entorhinal Cortex Recruit Cholinergic and NMDA Receptors Separately to Generate Hippocampal Theta Oscillations] [Synopsis Hippocampus and Entorhinal Cortex Recruit Cholinergic and NMDA Receptors Separately to Generate Hippocampal Theta Oscillations] Gu Z, Alexander GM, Dudek SM, Yakel JL. December 2017

Association of Air Particulate Pollution With Bone Loss Over Time and Bone Fracture Risk: Analysis of Data From Two Independent Studies [Abstract Association of Air Particulate Pollution With Bone Loss Over Time and Bone Fracture Risk: Analysis of Data From Two Independent Studies] [Synopsis Association of Air Particulate Pollution With Bone Loss Over Time and Bone Fracture Risk: Analysis of Data From Two Independent Studies] Prada D, Zhong J, Colicino E, Zanobetti A, Schwartz J, Dagincourt N, Fang SC, Kloog I , Zmuda JM, Holick M, Herrera LA, Hou L, Dominici F, Bartali B, Baccarelli AA. November 2017

Bedroom Allergen Exposures in U.S. Households [Abstract Bedroom Allergen Exposures in U.S. Households] [Synopsis Bedroom Allergen Exposures in U.S. Households] [Story Bedroom Allergen Exposures in U.S. Households] Salo PM, Wilkerson J, Rose KM, Cohn RD, Calatroni A, Mitchell HE, Sever ML, Gergen PJ, Thorne PS, Zeldin DC. November 2017

Burden of Higher Lead Exposure in African-Americans Starts In Utero and Persists Into Childhood [Abstract Burden of Higher Lead Exposure in African-Americans Starts In Utero and Persists Into Childhood] [Synopsis Burden of Higher Lead Exposure in African-Americans Starts In Utero and Persists Into Childhood] Cassidy-Bushrow AE, Sitarik AR, Havstad S, Park SK, Bielak LF, Austin C, Johnson CC, Arora M. November 2017

Inflammation-induced IgA+ Cells Dismantle Anti-Liver Cancer Immunity [Abstract Inflammation-induced IgA+ Cells Dismantle Anti-Liver Cancer Immunity] [Synopsis Inflammation-induced IgA+ Cells Dismantle Anti-Liver Cancer Immunity] [Story Inflammation-induced IgA+ Cells Dismantle Anti-Liver Cancer Immunity] Shalapour S, Lin XJ, Bastian IN, Brain J, Burt AD, Aksenov AA, Vrbanac AF, Li W, Perkins A, Matsutani T, Zhong Z, Dhar D, Navas-Molina JA, Xu J, Loomba R, Downes M, Yu RT, Evans RM, Dorrestein PC, Knight R, Benner C, Anstee QM, Karin M. November 2017

KO of 5-InsP7 Kinase Activity Transforms the HCT116 Colon Cancer Cell Line Into a Hypermetabolic, Growth-Inhibited Phenotype [Abstract KO of 5-InsP7 Kinase Activity Transforms the HCT116 Colon Cancer Cell Line Into a Hypermetabolic, Growth-Inhibited Phenotype] [Synopsis KO of 5-InsP7 Kinase Activity Transforms the HCT116 Colon Cancer Cell Line Into a Hypermetabolic, Growth-Inhibited Phenotype] Gu C, Nguyen HN, Ganini D, Chen Z, Jessen HJ, Gu Z, Wang H, Shears SB. November 2017

Pathogenic Th17 Inflammation Is Sustained In the Lungs By Conventional Dendritic Cells and TLR4 Signaling [Abstract Pathogenic Th17 Inflammation Is Sustained In the Lungs By Conventional Dendritic Cells and TLR4 Signaling] [Synopsis Pathogenic Th17 Inflammation Is Sustained In the Lungs By Conventional Dendritic Cells and TLR4 Signaling] Shalaby KH, Lyons-Cohen MR, Whitehead GS, Thomas SY, Prinz I, Nakano H, Cook DN. November 2017

Taurine Ameliorates Particulate Matter-induced Emphysema By Switching On Mitochondrial NADH Dehydrogenase Genes [Abstract Taurine Ameliorates Particulate Matter-induced Emphysema By Switching On Mitochondrial NADH Dehydrogenase Genes] [Synopsis Taurine Ameliorates Particulate Matter-induced Emphysema By Switching On Mitochondrial NADH Dehydrogenase Genes] Li X, Yang H, Sun H, Lu R, Zhang C, Gao N, Meng Q, Wu S, Wang S, Aschner M, Wu J, Tang B, Gu A, Kay SA, Chen R. November 2017

An Investigation of the Single and Combined Phthalate Metabolite Effects on Human Chorionic Gonadotropin Expression in Placental Cells [Abstract An Investigation of the Single and Combined Phthalate Metabolite Effects on Human Chorionic Gonadotropin Expression in Placental Cells] [Synopsis An Investigation of the Single and Combined Phthalate Metabolite Effects on Human Chorionic Gonadotropin Expression in Placental Cells] Adibi JJ, Zhao Y, Zhan LV, Kapidzic M, Larocque N, Koistinen H, Huhtaniemi IT, Stenman UH. October 2017

A Predictive Model to Identify Parkinson Disease from Administrative Claims Data [Abstract A Predictive Model to Identify Parkinson Disease from Administrative Claims Data] [Synopsis A Predictive Model to Identify Parkinson Disease from Administrative Claims Data] Searles Nielsen S, Warden MN, Camacho-Soto A, Willis AW, Wright BA, Racette BA. October 2017

Association Between Biomarkers of Ovarian Reserve and Infertility Among Older Women of Reproductive Age [Abstract Association Between Biomarkers of Ovarian Reserve and Infertility Among Older Women of Reproductive Age] [Synopsis Association Between Biomarkers of Ovarian Reserve and Infertility Among Older Women of Reproductive Age] [Story Association Between Biomarkers of Ovarian Reserve and Infertility Among Older Women of Reproductive Age] Steiner AZ, Pritchard D, Stanczyk FZ, Kesner JS, Meadows JW, Herring AH, Baird DD. October 2017

BRCA1-BARD1 Promotes RAD51-mediated Homologous DNA Pairing [Abstract BRCA1-BARD1 Promotes RAD51-mediated Homologous DNA Pairing] [Synopsis BRCA1-BARD1 Promotes RAD51-mediated Homologous DNA Pairing] Zhao W, Steinfeld JB, Liang F, Chen X, Maranon DG, Jian Ma C, Kwon Y, Rao T, Wang W, Sheng C, Song X, Deng Y, Jimenez-Sainz J, Lu L, Jensen RB, Xiong Y, Kupfer GM, Wiese C, Greene EC, Sung P. October 2017

GLIS3 Is Indispensable For TSH/TSHR-dependent Thyroid Hormone Biosynthesis and Follicular Cell Proliferation [Abstract GLIS3 Is Indispensable For TSH/TSHR-dependent Thyroid Hormone Biosynthesis and Follicular Cell Proliferation] [Synopsis GLIS3 Is Indispensable For TSH/TSHR-dependent Thyroid Hormone Biosynthesis and Follicular Cell Proliferation] Kang HS, Kumar D, Liao G, Lichti-Kaiser K, Gerrish K, Liao XH, Refetoff S, Jothi R, Jetten AM. October 2017

Intragenic Enhancers Attenuate Host Gene Expression [Abstract Intragenic Enhancers Attenuate Host Gene Expression] [Synopsis Intragenic Enhancers Attenuate Host Gene Expression] [Story Intragenic Enhancers Attenuate Host Gene Expression] Cinghu S, Yang P, Kosak JP, Conway AE, Kumar D, Oldfield AJ, Adelman K, Jothi R. October 2017

Modulating the DNA Polymerase Beta Reaction Equilibrium to Dissect the Reverse Reaction [Abstract Modulating the DNA Polymerase Beta Reaction Equilibrium to Dissect the Reverse Reaction] [Synopsis Modulating the DNA Polymerase Beta Reaction Equilibrium to Dissect the Reverse Reaction] Shock DD, Freudenthal BD, Beard WA, Wilson SH. October 2017

Rif1 Promotes a Repressive Chromatin State To Safeguard Against Endogenous Retrovirus Activation [Abstract Rif1 Promotes a Repressive Chromatin State To Safeguard Against Endogenous Retrovirus Activation] [Synopsis Rif1 Promotes a Repressive Chromatin State To Safeguard Against Endogenous Retrovirus Activation] Li P, Wang L, Bennett BD, Wang J, Li J, Qin Y, Takaku M, Wade PA, Wong J, Hu G. October 2017

Systems-Level Annotation of a Metabolomics Data Set Reduces 25,000 Features to Fewer than 1000 Unique Metabolites [Abstract Systems-Level Annotation of a Metabolomics Data Set Reduces 25,000 Features to Fewer than 1000 Unique Metabolites] [Synopsis Systems-Level Annotation of a Metabolomics Data Set Reduces 25,000 Features to Fewer than 1000 Unique Metabolites] Mahieu NG, Patti GJ. October 2017

The Effect of the Environmental Protection Agency Maximum Contaminant Level on Arsenic Exposure in the USA from 2003 to 2014: An Analysis of the National Health and Nutrition Examination Survey (NHANES) [Abstract The Effect of the Environmental Protection Agency Maximum Contaminant Level on Arsenic Exposure in the USA from 2003 to 2014: An Analysis of the National Health and Nutrition Examination Survey (NHANES)] [Synopsis The Effect of the Environmental Protection Agency Maximum Contaminant Level on Arsenic Exposure in the USA from 2003 to 2014: An Analysis of the National Health and Nutrition Examination Survey (NHANES)] Nigra AE, Sanchez TR, Nachman KE, Harvey DE, Chillrud SN, Graziano JH, Navas-Acien A. October 2017

Antimullerian Hormone in Relation to Tobacco and Marijuana Use and Sources of Indoor Heating/Cooking [Abstract Antimullerian Hormone in Relation to Tobacco and Marijuana Use and Sources of Indoor Heating/Cooking] [Synopsis Antimullerian Hormone in Relation to Tobacco and Marijuana Use and Sources of Indoor Heating/Cooking] White AJ, Sandler DP, D’Aloisio AA, Stanczyk F, Whitworth KW, Baird DD, Nichols HB. September 2017

Association of Ozone Exposure with Cardiorespiratory Pathophysiologic Mechanisms in Healthy Adults [Abstract Association of Ozone Exposure with Cardiorespiratory Pathophysiologic Mechanisms in Healthy Adults] [Synopsis Association of Ozone Exposure with Cardiorespiratory Pathophysiologic Mechanisms in Healthy Adults] Day DB, Xiang J, Mo J, Li F, Chung M, Gong J, Weschler CJ, Ohman-Strickland PA, Sundell J, Weng W, Zhang Y, Zhang JJ. September 2017

Complementation of Aprataxin Deficiency By Base Excision Repair Enzymes in Mitochondrial Extracts [Abstract Complementation of Aprataxin Deficiency By Base Excision Repair Enzymes in Mitochondrial Extracts] [Synopsis Complementation of Aprataxin Deficiency By Base Excision Repair Enzymes in Mitochondrial Extracts] Caglayan M, Prasad R, Krasich R, Longley MJ, Kadoda K, Tsuda M, Sasanuma H, Takeda S, Tano K, Copeland WC, Wilson SH. September 2017

Development and Pilot Testing of a Model to Translate Risk Assessment Data for Great Lakes Native American Communities Using Mobile Technology [Abstract Development and Pilot Testing of a Model to Translate Risk Assessment Data for Great Lakes Native American Communities Using Mobile Technology] [Synopsis Development and Pilot Testing of a Model to Translate Risk Assessment Data for Great Lakes Native American Communities Using Mobile Technology] Dellinger MJ, Olson J, Clark R, Pingatore N, Ripley MP. September 2017

Impact of Air Manganese on Child Neurodevelopment in East Liverpool, Ohio [Abstract Impact of Air Manganese on Child Neurodevelopment in East Liverpool, Ohio] [Synopsis Impact of Air Manganese on Child Neurodevelopment in East Liverpool, Ohio] Haynes EN, Sucharew H, Hilbert TJ, Kuhnell P, Spencer A, Newman NC, Burns R, Wright R, Parsons PJ, Dietrich KN. September 2017

Prenatal Naled and Chlorpyrifos Exposure is Associated with Deficits in Infant Motor Function in a Cohort of Chinese Infants [Abstract Prenatal Naled and Chlorpyrifos Exposure is Associated with Deficits in Infant Motor Function in a Cohort of Chinese Infants] [Synopsis Prenatal Naled and Chlorpyrifos Exposure is Associated with Deficits in Infant Motor Function in a Cohort of Chinese Infants] Silver MK, Shao J, Zhu B, Chen M, Xia Y, Kaciroti N, Lozoff B, Meeker JD. September 2017

Structural Accommodation of Ribonucleotide Incorporation by the DNA Repair Enzyme Polymerase Mu [Abstract Structural Accommodation of Ribonucleotide Incorporation by the DNA Repair Enzyme Polymerase Mu] [Synopsis Structural Accommodation of Ribonucleotide Incorporation by the DNA Repair Enzyme Polymerase Mu] Moon AF, Pryor JM, Ramsden DA, Kunkel TA, Bebenek K, Pedersen LC. September 2017

Three-Dimensional (3D) HepaRG Spheroid Model With Physiologically Relevant Xenobiotic Metabolism Competence and Hepatocyte Functionality for Liver Toxicity Screening [Abstract Three-Dimensional (3D) HepaRG Spheroid Model With Physiologically Relevant Xenobiotic Metabolism Competence and Hepatocyte Functionality for Liver Toxicity Screening] [Synopsis Three-Dimensional (3D) HepaRG Spheroid Model With Physiologically Relevant Xenobiotic Metabolism Competence and Hepatocyte Functionality for Liver Toxicity Screening] Ramaiahgari SC, Waidyanatha S, Dixon D, DeVito MJ, Paules RS, Ferguson SS. September 2017

TNF Is Required for TLR Ligand-Mediated But Not Protease-Mediated Allergic Airway Inflammation [Abstract TNF Is Required for TLR Ligand-Mediated But Not Protease-Mediated Allergic Airway Inflammation] [Synopsis TNF Is Required for TLR Ligand-Mediated But Not Protease-Mediated Allergic Airway Inflammation] Whitehead GS, Thomas SY, Shalaby KH, Nakano K, Moran TP, Ward JM, Flake GP, Nakano H, Cook DN. September 2017

Assessment of the DNA Damaging Potential of Environmental Chemicals Using a Quantitative High-Throughput Screening Approach to Measure p53 Activation [Abstract Assessment of the DNA Damaging Potential of Environmental Chemicals Using a Quantitative High-Throughput Screening Approach to Measure p53 Activation] [Synopsis Assessment of the DNA Damaging Potential of Environmental Chemicals Using a Quantitative High-Throughput Screening Approach to Measure p53 Activation] Witt KL, Hsieh JH, Smith-Roe SL, Xia M, Huang R, Zhao J, Auerbach SS, Hur J, Tice RR. August 2017

Estimated Exposures to Perfluorinated Compounds in Infancy Predict Attenuated Vaccine Antibody Concentrations at Age 5-Years [Abstract Estimated Exposures to Perfluorinated Compounds in Infancy Predict Attenuated Vaccine Antibody Concentrations at Age 5-Years] [Synopsis Estimated Exposures to Perfluorinated Compounds in Infancy Predict Attenuated Vaccine Antibody Concentrations at Age 5-Years] Grandjean P, Heilmann C, Weihe P, Nielsen F, Mogensen UB, Timmermann A, Budtz-Jorgensen E. August 2017

Evaluation of the Respiratory Tract Toxicity of Ortho-Phthalaldehyde, a Proposed Alternative For the Chemical Disinfectant Glutaraldehyde [Abstract Evaluation of the Respiratory Tract Toxicity of Ortho-Phthalaldehyde, a Proposed Alternative For the Chemical Disinfectant Glutaraldehyde] [Synopsis Evaluation of the Respiratory Tract Toxicity of Ortho-Phthalaldehyde, a Proposed Alternative For the Chemical Disinfectant Glutaraldehyde] Catlin NR, Willson CJ, Stout M, Kissling GE, Waidyanatha S, Baker GL, Hayden BK, Wyde M. August 2017

Histologic and Biochemical Alterations Predict Pulmonary Mechanical Dysfunction in Aging Mice with Chronic Lung Inflammation [Abstract Histologic and Biochemical Alterations Predict Pulmonary Mechanical Dysfunction in Aging Mice with Chronic Lung Inflammation] [Synopsis Histologic and Biochemical Alterations Predict Pulmonary Mechanical Dysfunction in Aging Mice with Chronic Lung Inflammation] Massa CB, Groves AM, Jaggernauth SU, Laskin DL, Gow AJ. August 2017

Time-Lapse Crystallography Snapshots of a Double-Strand Break Repair Polymerase in Action [Abstract Time-Lapse Crystallography Snapshots of a Double-Strand Break Repair Polymerase in Action] [Synopsis Time-Lapse Crystallography Snapshots of a Double-Strand Break Repair Polymerase in Action] Jamsen JA, Beard WA, Pedersen LC, Shock DD, Moon AF, Krahn JM, Bebenek K, Kunkel TA, Wilson SH. August 2017

Urinary Concentrations of Organophosphate Flame Retardant Metabolites and Pregnancy Outcomes among Women Undergoing in Vitro Fertilization [Abstract Urinary Concentrations of Organophosphate Flame Retardant Metabolites and Pregnancy Outcomes among Women Undergoing in Vitro Fertilization] [Synopsis Urinary Concentrations of Organophosphate Flame Retardant Metabolites and Pregnancy Outcomes among Women Undergoing in Vitro Fertilization] Carignan CC, Minguez-Alarcon L, Butt CM, Williams PL, Meeker JD, Stapleton HM, Toth TL, Ford JB, Hauser R, EARTH Study Team. August 2017

Airborne PCBs and OH-PCBs Inside and Outside Urban and Rural U.S. Schools [Abstract Airborne PCBs and OH-PCBs Inside and Outside Urban and Rural U.S. Schools] [Synopsis Airborne PCBs and OH-PCBs Inside and Outside Urban and Rural U.S. Schools] Marek RF, Thorne PS, Herkert NJ, Awad AM, Hornbuckle KC. July 2017

Characterizing Properties of Non-estrogenic Substituted Bisphenol Analogs Using High Throughput Microscopy and Image Analysis [Abstract Characterizing Properties of Non-estrogenic Substituted Bisphenol Analogs Using High Throughput Microscopy and Image Analysis] [Synopsis Characterizing Properties of Non-estrogenic Substituted Bisphenol Analogs Using High Throughput Microscopy and Image Analysis] Szafran AT, Stossi F, Mancini MG, Walker CL, Mancini MA. July 2017

Epigenome-Wide Association Study of Chronic Obstructive Pulmonary Disease and Lung Function in Koreans [Abstract Epigenome-Wide Association Study of Chronic Obstructive Pulmonary Disease and Lung Function in Koreans] [Synopsis Epigenome-Wide Association Study of Chronic Obstructive Pulmonary Disease and Lung Function in Koreans] Lee MK, Hong Y, Kim SY, Kim WJ, London SJ. July 2017

Grc3 Programs the Essential Endoribonuclease Las1 for Specific RNA Cleavage [Abstract Grc3 Programs the Essential Endoribonuclease Las1 for Specific RNA Cleavage] [Synopsis Grc3 Programs the Essential Endoribonuclease Las1 for Specific RNA Cleavage] Pillon MC, Sobhany M, Borgnia MJ, Williams JG, Stanley RE. July 2017

Mismatch Repair Proteins Initiate Epigenetic Alterations during Inflammation-Driven Tumorigenesis [Abstract Mismatch Repair Proteins Initiate Epigenetic Alterations during Inflammation-Driven Tumorigenesis] [Synopsis Mismatch Repair Proteins Initiate Epigenetic Alterations during Inflammation-Driven Tumorigenesis] Maiuri AR, Peng M, Sriramkumar S, Kamplain CM, DeStefano Sheilds CE, Sears CL, O’Hagan HM. July 2017

Nonsynonymous Polymorphisms in the Human AS3MT Arsenic Methylation Gene: Implications for Arsenic Toxicity [Abstract Nonsynonymous Polymorphisms in the Human AS3MT Arsenic Methylation Gene: Implications for Arsenic Toxicity] [Synopsis Nonsynonymous Polymorphisms in the Human AS3MT Arsenic Methylation Gene: Implications for Arsenic Toxicity] Li J, Packianathan C, Rossman TG, Rosen BP. July 2017

Pesticide Use and Age-Related Macular Degeneration in the Agricultural Health Study [Abstract Pesticide Use and Age-Related Macular Degeneration in the Agricultural Health Study] [Synopsis Pesticide Use and Age-Related Macular Degeneration in the Agricultural Health Study] Montgomery MP, Postel E, Umbach DM, Richards M, Watson M, Blair A, Chen H, Sandler DP, Schmidt S, Kamel F. July 2017

Sectioning Mammary Gland Whole Mounts for Lesion Identification [Abstract Sectioning Mammary Gland Whole Mounts for Lesion Identification] [Synopsis Sectioning Mammary Gland Whole Mounts for Lesion Identification] Tucker DK, Foley JF, Bouknight SA, Fenton SE. July 2017

Sensitization and Exposure to Pets: The Effect on Asthma Morbidity in the U.S. Population [Abstract Sensitization and Exposure to Pets: The Effect on Asthma Morbidity in the U.S. Population] [Synopsis Sensitization and Exposure to Pets: The Effect on Asthma Morbidity in the U.S. Population] Gergen PJ, Mitchell HE, Sever ML, Cohn RD, Salo PM, Thorne PS, Zeldin DC. July 2017

Air Pollution and Mortality in the Medicare Population [Abstract Air Pollution and Mortality in the Medicare Population] [Synopsis Air Pollution and Mortality in the Medicare Population] Di Q, Wang Y, Zanobetti A, Wang Y, Koutrakis P, Choirat C, Dominici F, Schwartz JD. June 2017

Ambient and Dosed Exposure to Quaternary Ammonium Disinfectants Causes Neural Tube Defects in Rodents [Abstract Ambient and Dosed Exposure to Quaternary Ammonium Disinfectants Causes Neural Tube Defects in Rodents] [Synopsis Ambient and Dosed Exposure to Quaternary Ammonium Disinfectants Causes Neural Tube Defects in Rodents] Hrubec TC, Melin VE, Shea CS, Ferguson EE, Garofola C, Repine CM, Chapman TW, Patel HR, Razvi RM, Sugrue JE, Potineni H, Magnin-Bissel G, Hunt PA. June 2017

Fetal and Postnatal Metal Dysregulation in Autism [Abstract Fetal and Postnatal Metal Dysregulation in Autism] [Synopsis Fetal and Postnatal Metal Dysregulation in Autism] [Story Fetal and Postnatal Metal Dysregulation in Autism] Arora M, Reichenberg A, Willfors C, Austin C, Gennings C, Berggren S, Lichtenstein P, Anckarsater H, Tammimies K, Bolte S. June 2017

Nucleotide Excision Repair Lesion-Recognition Protein Rad4 Captures a Pre-Flipped Partner Base in a Benzo[a]pyrene-Derived DNA Lesion: How Structure Impacts the Binding Pathway [Abstract Nucleotide Excision Repair Lesion-Recognition Protein Rad4 Captures a Pre-Flipped Partner Base in a Benzo[a]pyrene-Derived DNA Lesion: How Structure Impacts the Binding Pathway] [Synopsis Nucleotide Excision Repair Lesion-Recognition Protein Rad4 Captures a Pre-Flipped Partner Base in a Benzo[a]pyrene-Derived DNA Lesion: How Structure Impacts the Binding Pathway] Mu H, Geacintov NE, Min JH, Zhang Y, Broyde S. June 2017

Role of ER-alpha in Mediating Female Uterine Transcriptional Responses to IGF1 [Abstract Role of ER-alpha in Mediating Female Uterine Transcriptional Responses to IGF1] [Synopsis Role of ER-alpha in Mediating Female Uterine Transcriptional Responses to IGF1] Hewitt SC, Winuthayanon W, Lierz SL, Hamilton KJ, Donoghue LJ, Ramsey JT, Grimm SA, Arao Y, Korach KS. June 2017

Season of Conception, Smoking, and Preeclampsia in Norway [Abstract Season of Conception, Smoking, and Preeclampsia in Norway] [Synopsis Season of Conception, Smoking, and Preeclampsia in Norway] Weinberg CR, Shi M, Basso O, DeRoo LA, Harmon Q, Wilcox AJ, Skjaerven R. June 2017

Association of Air Pollution Exposures with High-Density Lipoprotein Cholesterol and Particle Number: The Multi-Ethnic Study of Atherosclerosis [Abstract Association of Air Pollution Exposures with High-Density Lipoprotein Cholesterol and Particle Number: The Multi-Ethnic Study of Atherosclerosis] [Synopsis Association of Air Pollution Exposures with High-Density Lipoprotein Cholesterol and Particle Number: The Multi-Ethnic Study of Atherosclerosis] Bell G, Mora S, Greenland P, Tsai M, Gill E, Kaufman JD. May 2017

Cnot3 Enhances Human Embryonic Cardiomyocyte Proliferation by Promoting Cell Cycle Inhibitor mRNA Degradation [Abstract Cnot3 Enhances Human Embryonic Cardiomyocyte Proliferation by Promoting Cell Cycle Inhibitor mRNA Degradation] [Synopsis Cnot3 Enhances Human Embryonic Cardiomyocyte Proliferation by Promoting Cell Cycle Inhibitor mRNA Degradation] Zhou B, Liu J, Ren Z, Yao F, Ma J, Song J, Bennett B, Zhen Y, Wang L, Hu G, Hu S. May 2017

Genomic Biomarkers of Prenatal Intrauterine Inflammation in Umbilical Cord Tissue Predict Later Life Neurological Outcomes [Abstract Genomic Biomarkers of Prenatal Intrauterine Inflammation in Umbilical Cord Tissue Predict Later Life Neurological Outcomes] [Synopsis Genomic Biomarkers of Prenatal Intrauterine Inflammation in Umbilical Cord Tissue Predict Later Life Neurological Outcomes] Tilley SK, Joseph RM, Kuban KCK, Dammann OU, O'Shea TM, Fry RC. May 2017

House Dust Endotoxin and Peripheral Leukocyte Counts: Results from Two Large Epidemiologic Studies [Abstract House Dust Endotoxin and Peripheral Leukocyte Counts: Results from Two Large Epidemiologic Studies] [Synopsis House Dust Endotoxin and Peripheral Leukocyte Counts: Results from Two Large Epidemiologic Studies] Fessler MB, Carnes MU, Salo PM, Wilkerson J, Cohn RD, King D, Hoppin JA, Sandler DP, Travlos G, London SJ, Thorne PS, Zeldin DC. May 2017

Metagenomic Discovery of Polybrominated Diphenyl Ether Biosynthesis by Marine Sponges [Abstract Metagenomic Discovery of Polybrominated Diphenyl Ether Biosynthesis by Marine Sponges] [Synopsis Metagenomic Discovery of Polybrominated Diphenyl Ether Biosynthesis by Marine Sponges] Agarwal V, Blanton JM, Podell S, Taton A, Schorn MA, Busch J, Lin Z, Schmidt EW, Jensen PR, Paul VJ, Biggs JS, Golden JW, Allen EE, Moore BS. May 2017

Phthalates and Thyroid Function in Preschool Age Children: Sex Specific Associations [Abstract Phthalates and Thyroid Function in Preschool Age Children: Sex Specific Associations] [Synopsis Phthalates and Thyroid Function in Preschool Age Children: Sex Specific Associations] Morgenstern R, Whyatt RM, Insel BJ, Calafat AM, Liu X, Rauh VA, Herbstman J, Bradwin G, Factor-Litvak P. May 2017

Potential Short-Term Neurobehavioral Alterations in Children Associated With a Peak Pesticide Spray Season: The Mother’s Day Flower Harvest in Ecuador [Abstract Potential Short-Term Neurobehavioral Alterations in Children Associated With a Peak Pesticide Spray Season: The Mother’s Day Flower Harvest in Ecuador] [Synopsis Potential Short-Term Neurobehavioral Alterations in Children Associated With a Peak Pesticide Spray Season: The Mother’s Day Flower Harvest in Ecuador] Suarez-Lopez JR, Checkoway H, Jacobs DR Jr, Al-Delaimy WK, Gahagan S. May 2017

Real-Time Cell Toxicity Profiling of Tox21 10K Compounds Reveals Cytotoxicity Dependent Toxicity Pathway Linkage [Abstract Real-Time Cell Toxicity Profiling of Tox21 10K Compounds Reveals Cytotoxicity Dependent Toxicity Pathway Linkage] [Synopsis Real-Time Cell Toxicity Profiling of Tox21 10K Compounds Reveals Cytotoxicity Dependent Toxicity Pathway Linkage] Hsieh JH, Huang R, Lin JA, Sedykh A, Zhao J, Tice RR, Paules RS, Xia M, Auerbach SS. May 2017

Structural Analysis Reveals Features of Ribosome Assembly Factor Nsa1/WDR74 Important for Localization and Interaction with Rix7/NVL2 [Abstract Structural Analysis Reveals Features of Ribosome Assembly Factor Nsa1/WDR74 Important for Localization and Interaction with Rix7/NVL2] [Synopsis Structural Analysis Reveals Features of Ribosome Assembly Factor Nsa1/WDR74 Important for Localization and Interaction with Rix7/NVL2] Lo YH, Romes EM, Pillon MC, Sobhany M, Stanley RE. May 2017

The Phosphorylation Status of T522 Modulates Tissue-Specific Functions of SIRT1 in Energy Metabolism in Mice [Abstract The Phosphorylation Status of T522 Modulates Tissue-Specific Functions of SIRT1 in Energy Metabolism in Mice] [Synopsis The Phosphorylation Status of T522 Modulates Tissue-Specific Functions of SIRT1 in Energy Metabolism in Mice] Lu J, Xu Q, Ji M, Guo X, Xu X, Fargo DC, Li X. May 2017

Drought and the Risk of Hospital Admissions and Mortality in Older Adults in Western USA from 2000 to 2013: A Retrospective Study [Synopsis Drought and the Risk of Hospital Admissions and Mortality in Older Adults in Western USA from 2000 to 2013: A Retrospective Study] [Story Drought and the Risk of Hospital Admissions and Mortality in Older Adults in Western USA from 2000 to 2013: A Retrospective Study] Berman JD, Ebisu K, Peng RD, Dominici F, Bell ML. April 2017

Integrating Drug’s Mode of Action into Quantitative Structure-Activity Relationships for Improved Prediction of Drug-Induced Liver Injury [Abstract Integrating Drug’s Mode of Action into Quantitative Structure-Activity Relationships for Improved Prediction of Drug-Induced Liver Injury] [Synopsis Integrating Drug’s Mode of Action into Quantitative Structure-Activity Relationships for Improved Prediction of Drug-Induced Liver Injury] Wu L, Liu Z, Auerbach S, Huang R, Chen M, McEuen K, Xu J, Fang H, Tong W. April 2017

Mutational Spectra of Aflatoxin B1 In Vivo Establish Biomarkers of Exposure For Human Hepatocellular Carcinoma [Abstract Mutational Spectra of Aflatoxin B1 In Vivo Establish Biomarkers of Exposure For Human Hepatocellular Carcinoma] [Synopsis Mutational Spectra of Aflatoxin B1 In Vivo Establish Biomarkers of Exposure For Human Hepatocellular Carcinoma] [Story Mutational Spectra of Aflatoxin B1 In Vivo Establish Biomarkers of Exposure For Human Hepatocellular Carcinoma] Chawanthayatham S, Valentine CC 3rd, Fedeles BI, Fox EJ, Loeb LA, Levine SS, Slocum SL, Wogan GN, Croy RG, Essigmann JM. April 2017

The Drosophila hnRNP F/H Homolog Glorund Uses Two Distinct RNA-Binding Modes to Diversify Target Recognition [Abstract The Drosophila hnRNP F/H Homolog Glorund Uses Two Distinct RNA-Binding Modes to Diversify Target Recognition] [Synopsis The Drosophila hnRNP F/H Homolog Glorund Uses Two Distinct RNA-Binding Modes to Diversify Target Recognition] Tamayo JV, Teramoto T, Chatterjee S, Hall TMT, Gavis ER. April 2017

Urinary Polycyclic Aromatic Hydrocarbon Metabolite Associations with Biomarkers of Inflammation, Angiogenesis, and Oxidative Stress in Pregnant Women [Abstract Urinary Polycyclic Aromatic Hydrocarbon Metabolite Associations with Biomarkers of Inflammation, Angiogenesis, and Oxidative Stress in Pregnant Women] [Synopsis Urinary Polycyclic Aromatic Hydrocarbon Metabolite Associations with Biomarkers of Inflammation, Angiogenesis, and Oxidative Stress in Pregnant Women] Ferguson KK, McElrath TF, Pace GG, Weller D, Zeng L, Pennathur S, Cantonwine DE, Meeker JD. April 2017

A Microfluidic Culture Model of the Human Reproductive Tract and 28-Day Menstrual Cycle [Abstract A Microfluidic Culture Model of the Human Reproductive Tract and 28-Day Menstrual Cycle] [Synopsis A Microfluidic Culture Model of the Human Reproductive Tract and 28-Day Menstrual Cycle] [Story A Microfluidic Culture Model of the Human Reproductive Tract and 28-Day Menstrual Cycle] Xiao S, Coppeta JR, Rogers HB, Isenberg BC, Zhu J, Olalekan SA, McKinnon KE, Dokic D, Rashedi AS, Haisenleder DJ, Malpani SS, Arnold-Murray CA, Chen K, Jiang M, Bai L, Nguyen CT, Zhang J, Laronda MM, Hope TJ, Maniar KP, Pavone ME, Avram MJ, Sefton EC, Getsios S, Burdette JE, Kim JJ, Borenstein JT, Woodruff TK. March 2017

B Vitamins Attenuate the Epigenetic Effects of Ambient Fine Particles In a Pilot Human Intervention Trial [Abstract B Vitamins Attenuate the Epigenetic Effects of Ambient Fine Particles In a Pilot Human Intervention Trial] [Synopsis B Vitamins Attenuate the Epigenetic Effects of Ambient Fine Particles In a Pilot Human Intervention Trial] Zhong J, Karlsson O, Wang G, Li J, Guo Y, Lin X, Zemplenyi M, Sanchez-Guerra M, Trevisi L, Urch B, Speck M, Liang L, Coull BA, Koutrakis P, Silverman F, Gold DR, Wu T, Baccarelli AA. March 2017

Effect of an Integrated Pest Management Intervention on Asthma Symptoms Among Mouse-Sensitized Children and Adolescents With Asthma: A Randomized Clinical Trial [Abstract Effect of an Integrated Pest Management Intervention on Asthma Symptoms Among Mouse-Sensitized Children and Adolescents With Asthma: A Randomized Clinical Trial] [Synopsis Effect of an Integrated Pest Management Intervention on Asthma Symptoms Among Mouse-Sensitized Children and Adolescents With Asthma: A Randomized Clinical Trial] Matsui EC, Perzanowski M, Peng RD, Wise RA, Balcer-Whaley S, Newman M, Cunningham A, Divjan A, Bollinger ME, Zhai S, Chew G, Miller RL, Phipatanakul W. March 2017

Evaluation of 4-methylcyclohexanemethanol (MCHM) In a Combined Irritancy and Local Lymph Node Assay (LLNA) In Mice [Abstract Evaluation of 4-methylcyclohexanemethanol (MCHM) In a Combined Irritancy and Local Lymph Node Assay (LLNA) In Mice] [Synopsis Evaluation of 4-methylcyclohexanemethanol (MCHM) In a Combined Irritancy and Local Lymph Node Assay (LLNA) In Mice] Johnson VJ, Auerbach SS, Luster MI, Waidyanatha S, Masten SA, Wolfe MS, Burleson FG, Burleson GR, Germolec DR. March 2017

Fluorescent Proteins Such as eGFP Lead to Catalytic Oxidative Stress in Cells [Abstract Fluorescent Proteins Such as eGFP Lead to Catalytic Oxidative Stress in Cells] [Synopsis Fluorescent Proteins Such as eGFP Lead to Catalytic Oxidative Stress in Cells] Ganini D, Leinisch F, Kumar A, Jiang J, Tokar EJ, Malone CC, Petrovich RM, Mason RP. March 2017

Hormone Signaling and Fatty Liver in Females: Analysis of Estrogen Receptor Alpha Mutant Mice [Abstract Hormone Signaling and Fatty Liver in Females: Analysis of Estrogen Receptor Alpha Mutant Mice] [Synopsis Hormone Signaling and Fatty Liver in Females: Analysis of Estrogen Receptor Alpha Mutant Mice] Hart-Unger S, Arao Y, Hamilton KJ, Lierz SL, Malarkey DE, Hewitt SC, Freemark M, Korach KS. March 2017

Synaptic Vesical Glycoprotein 2C (SV2C) Modulates Dopamine Release and is Disrupted in Parkinson Disease [Abstract Synaptic Vesical Glycoprotein 2C (SV2C) Modulates Dopamine Release and is Disrupted in Parkinson Disease] [Synopsis Synaptic Vesical Glycoprotein 2C (SV2C) Modulates Dopamine Release and is Disrupted in Parkinson Disease] Dunn AR, Stout KA, Ozawa M, Lohr KM, Hoffman CA, Bernstein AI, Li Y, Wang M, Sgobio C, Sastry N, Cai H, Caudle WM, Miller GW. March 2017

The Significance of the Bifunctional Kinase/Phosphatase Activities of Diphosphoinositol Pentakisphosphate Kinases (PPIP5Ks) for Coupling Inositol Pyrophosphate Cell Signaling to Cellular Phosphate Homeostasis [Abstract The Significance of the Bifunctional Kinase/Phosphatase Activities of Diphosphoinositol Pentakisphosphate Kinases (PPIP5Ks) for Coupling Inositol Pyrophosphate Cell Signaling to Cellular Phosphate Homeostasis] [Synopsis The Significance of the Bifunctional Kinase/Phosphatase Activities of Diphosphoinositol Pentakisphosphate Kinases (PPIP5Ks) for Coupling Inositol Pyrophosphate Cell Signaling to Cellular Phosphate Homeostasis] Gu C, Nguyen HN, Hofer A, Jessen HJ, Dai X, Wang H, Shears SB. March 2017

DERBI: A Digital Method to Help Researchers Offer “Right-to-Know” Personal Exposure Results [Abstract DERBI: A Digital Method to Help Researchers Offer “Right-to-Know” Personal Exposure Results] [Synopsis DERBI: A Digital Method to Help Researchers Offer “Right-to-Know” Personal Exposure Results] Boronow KE, Susmann HP, Gajos KZ, Rudel RA, Arnold KC, Brown P, Morello-Frosch R, Havas L, Brody JG. February 2017

Haploinsufficiency of SIRT1 Enhances Glutamine Metabolism and Promotes Cancer Development [Abstract Haploinsufficiency of SIRT1 Enhances Glutamine Metabolism and Promotes Cancer Development] [Synopsis Haploinsufficiency of SIRT1 Enhances Glutamine Metabolism and Promotes Cancer Development] Ren NS, Ji M, Tokar EJ, Busch EL, Xu X, Lewis D, Li X, Jin A, Zhang Y, Wu WK, Huang W, Li L, Fargo DC, Keku TO, Sandler RS, Li X. February 2017

Occupational Factors and Markers of Ovarian Reserve and Response Among Women at a Fertility Centre [Abstract Occupational Factors and Markers of Ovarian Reserve and Response Among Women at a Fertility Centre] [Synopsis Occupational Factors and Markers of Ovarian Reserve and Response Among Women at a Fertility Centre] Minguez-Alarcon L, Souter I, Williams PL, Ford JB, Hauser R, Chavarro JE, Gaskins AJ, Earth Study Team. February 2017

Sex-Specific Effects of Organophosphate Diazinon on the Gut Microbiome and Its Metabolic Functions [Abstract Sex-Specific Effects of Organophosphate Diazinon on the Gut Microbiome and Its Metabolic Functions] [Synopsis Sex-Specific Effects of Organophosphate Diazinon on the Gut Microbiome and Its Metabolic Functions] Gao B, Bian X, Mahbub R, Lu K. February 2017

SMCHD1 Mutations Associated With a Rare Muscular Dystrophy Can Also Cause Isolated Arhinia and Bosma Arhinia Microphthalmia Syndrome [Abstract SMCHD1 Mutations Associated With a Rare Muscular Dystrophy Can Also Cause Isolated Arhinia and Bosma Arhinia Microphthalmia Syndrome] [Synopsis SMCHD1 Mutations Associated With a Rare Muscular Dystrophy Can Also Cause Isolated Arhinia and Bosma Arhinia Microphthalmia Syndrome] [Story SMCHD1 Mutations Associated With a Rare Muscular Dystrophy Can Also Cause Isolated Arhinia and Bosma Arhinia Microphthalmia Syndrome] Shaw ND, Brand H, Kupchinsky ZA, Bengani H, Plummer L, Jones TI, Erdin S, Williamson KA, Rainger J, Stortchevoi A, Samocha K, Currall BB, Dunican DS, Collins RL, Willer JR, Lek A, Lek M, Nassan M, Pereira S, Kammin T, Lucente D, Silva A, Seabra CM, Chiang C, An Y, Ansari M, Rainger JK, Joss S, Smith JC, Lippincott MF, Singh SS, Patel N, Jing JW, Law JR, Ferraro N, Verloes A, Rauch A, Steindl K, Zweier M, Scheer I, Sato D, Okamoto N, Jacobsen C, Tryggestad J, Chernausek S, Schimmenti LA, Brasseur B, Cesaretti C, Garcia-Ortiz JE, Beitrago TP, Silva OP, Hoffman JD, Muhlbauer W, Ruprecht KW, Loeys BL, Shino M, Kaindl AM, Cho CH, Morton CC, Meehan RR, van Heyningen V, Liao EC, Balasubramanian R, Hall JE, Seminara SB, Macarthur D, Moore SA, Yoshiura KI, Gusella JF, Marsh JA, Graham JM Jr, Lin AE, Katsanis N, Jones PL, Crowley WF Jr, Davis EE, Fitzpatrick DR, Talkowski ME. February 2017

A Black Cohosh Extract Causes Hematologic and Biochemical Changes Consistent with a Functional Cobalamin Deficiency in Female B6C3F1/N Mice [Abstract A Black Cohosh Extract Causes Hematologic and Biochemical Changes Consistent with a Functional Cobalamin Deficiency in Female B6C3F1/N Mice] [Synopsis A Black Cohosh Extract Causes Hematologic and Biochemical Changes Consistent with a Functional Cobalamin Deficiency in Female B6C3F1/N Mice] Cora MC, Gwinn W, Wilson R, King D, Waidyanatha S, Kissling GE, Brar SS, Olivera D, Blystone C, Travlos G. January 2017

APE2 Zf-GRF Facilitates 3’-5’ Resection of DNA Damage Following Oxidative Stress [Abstract APE2 Zf-GRF Facilitates 3’-5’ Resection of DNA Damage Following Oxidative Stress] [Synopsis APE2 Zf-GRF Facilitates 3’-5’ Resection of DNA Damage Following Oxidative Stress] Wallace BD, Berman Z, Mueller GA, Lin Y, Chang T, Andres SN, Wojtaszek JL, DeRose EF, Appel CD, London RE, Yan S, Williams RS. January 2017

Assessing the Suitability of Multiple Dispersion and Land Use Regression Models for Urban Traffic-Related Ultrafine Particles [Abstract Assessing the Suitability of Multiple Dispersion and Land Use Regression Models for Urban Traffic-Related Ultrafine Particles] [Synopsis Assessing the Suitability of Multiple Dispersion and Land Use Regression Models for Urban Traffic-Related Ultrafine Particles] Patton AP, Milando C, Durant JL, Kumar P. January 2017

Associations Among Personal Care Product Use Patterns and Exogenous Hormone Use in the NIEHS Sister Study [Abstract Associations Among Personal Care Product Use Patterns and Exogenous Hormone Use in the NIEHS Sister Study] [Synopsis Associations Among Personal Care Product Use Patterns and Exogenous Hormone Use in the NIEHS Sister Study] Taylor KW, Baird DD, Herring AH, Engel LS, Nichols HB, Sandler DP, Troester MA. January 2017

DNA Polymerase Beta Uses Its Lyase Domain in a Processive Search for DNA Damage [Abstract DNA Polymerase Beta Uses Its Lyase Domain in a Processive Search for DNA Damage] [Synopsis DNA Polymerase Beta Uses Its Lyase Domain in a Processive Search for DNA Damage] Howard MJ, Rodriguez Y, Wilson SH. January 2017

Dose-Dependent Progression of Parkinsonism in Manganese-Exposed Welders [Abstract Dose-Dependent Progression of Parkinsonism in Manganese-Exposed Welders] [Synopsis Dose-Dependent Progression of Parkinsonism in Manganese-Exposed Welders] Racette BA, Searles Nielsen S, Criswell SR, Sheppard L, Seixas N, Warden MN, Checkoway H. January 2017

Identifying Sensitive Windows for Prenatal Particulate Air Pollution Exposure and Mitochondrial DNA Content in Cord Blood [Abstract Identifying Sensitive Windows for Prenatal Particulate Air Pollution Exposure and Mitochondrial DNA Content in Cord Blood] [Synopsis Identifying Sensitive Windows for Prenatal Particulate Air Pollution Exposure and Mitochondrial DNA Content in Cord Blood] Rosa MJ, Just AC, Guerra MS, Kloog I, Hsu HL, Brennan KJ, Garcia AM, Coull B, Wright RJ, Tellez Rojo MM, Baccarelli AA, Wright RO. January 2017

In Silico Prediction of Physicochemical Properties of Environmental Chemicals Using Molecular Fingerprints and Machine Learning [Abstract In Silico Prediction of Physicochemical Properties of Environmental Chemicals Using Molecular Fingerprints and Machine Learning] [Synopsis In Silico Prediction of Physicochemical Properties of Environmental Chemicals Using Molecular Fingerprints and Machine Learning] Zang Q, Mansouri K, Williams AJ, Judson RS, Allen DG, Casey WM, Kleinstreuer NC. January 2017

New Insights Into Fetal Mammary Gland Morphogenesis: Differential Effects of Natural and Environmental Estrogens [Abstract New Insights Into Fetal Mammary Gland Morphogenesis: Differential Effects of Natural and Environmental Estrogens] [Synopsis New Insights Into Fetal Mammary Gland Morphogenesis: Differential Effects of Natural and Environmental Estrogens] Speroni L, Voutilainen M, Mikkola ML, Klager SA, Schaeberle CM, Sonnenschein C, Soto AM. January 2017

Oxidized Nucleotide Insertion by Pol Beta Confounds Ligation During Base Excision Repair [Abstract Oxidized Nucleotide Insertion by Pol Beta Confounds Ligation During Base Excision Repair] [Synopsis Oxidized Nucleotide Insertion by Pol Beta Confounds Ligation During Base Excision Repair] [Story Oxidized Nucleotide Insertion by Pol Beta Confounds Ligation During Base Excision Repair] Caglayan M, Horton JK, Dai DP, Stefanick DF, Wilson SH. January 2017

Systemic Exposure of Vinpocetine in Pregnant Sprague Dawley Rats Following Repeated Oral Exposure: An Investigation of Fetal Transfer [Abstract Systemic Exposure of Vinpocetine in Pregnant Sprague Dawley Rats Following Repeated Oral Exposure: An Investigation of Fetal Transfer] [Synopsis Systemic Exposure of Vinpocetine in Pregnant Sprague Dawley Rats Following Repeated Oral Exposure: An Investigation of Fetal Transfer] Waidyanatha S, Toy H, South N, Gibbs S, Mutlu E, Burback B, McIntyre BS, Catlin N. January 2018

The Association of Lead Exposure During Pregnancy and Childhood Anthropometry in the Mexican PROGRESS Cohort [Abstract The Association of Lead Exposure During Pregnancy and Childhood Anthropometry in the Mexican PROGRESS Cohort] [Synopsis The Association of Lead Exposure During Pregnancy and Childhood Anthropometry in the Mexican PROGRESS Cohort] Renzetti S, Just AC, Burris HH, Oken E, Amarasiriwardena C, Svensson K, Mercado-Garcia A, Cantoral A, Schnaas L, Baccarelli AA, Wright RO, Tellez-Rojo MM. January 2017

The Novel p53 Target TNFAIP8 Variant 2 Is Increased in Cancer and Offsets p53-Dependent Tumor Suppression [Abstract The Novel p53 Target TNFAIP8 Variant 2 Is Increased in Cancer and Offsets p53-Dependent Tumor Suppression] [Synopsis The Novel p53 Target TNFAIP8 Variant 2 Is Increased in Cancer and Offsets p53-Dependent Tumor Suppression] Lowe JM, Nguyen TA, Grimm SA, Gabor KA, Peddada SD, Li L, Anderson CW, Resnick MA, Menendez D, Fessler MB. January 2017

Cumulative Impact of Polychlorinated Biphenyl and Large Chromosomal Duplications on DNA Methylation, Chromatin, and Expression of Autism Candidate Genes [Abstract Cumulative Impact of Polychlorinated Biphenyl and Large Chromosomal Duplications on DNA Methylation, Chromatin, and Expression of Autism Candidate Genes] [Synopsis Cumulative Impact of Polychlorinated Biphenyl and Large Chromosomal Duplications on DNA Methylation, Chromatin, and Expression of Autism Candidate Genes] Dunaway KW, Islam MS, Coulson RL, Lopez SJ, Vogel Ciernia A, Chu RG, Yasui DH, Pessah IN, Lott P, Mordaunt C, Meguro-Horike M, Horike SI, Korf I, LaSalle JM. December 2016

Determinants of Host Susceptibility to Murine Respiratory Syncytial Virus (RSV) Disease Identify a Role for the Innate Immunity Scavenger Receptor MARCO Gene in Human Infants [Abstract Determinants of Host Susceptibility to Murine Respiratory Syncytial Virus (RSV) Disease Identify a Role for the Innate Immunity Scavenger Receptor MARCO Gene in Human Infants] [Synopsis Determinants of Host Susceptibility to Murine Respiratory Syncytial Virus (RSV) Disease Identify a Role for the Innate Immunity Scavenger Receptor MARCO Gene in Human Infants] High M, Cho HY, Marzec J, Wiltshire T, Verhein KC, Caballero MT, Acosta PL, Ciencewicki J, McCaw ZR, Kobzik L, Miller-DeGraff L, Gladwell W, Peden DB, Serra ME, Shi M, Weinberg C, Suzuki O, Wang X, Bell DA, Polack FP, Kleeberger SR. December 2016

DNA Polymerase Beta Contains a Functional Nuclear Localization Signal at its N-terminus [Abstract DNA Polymerase Beta Contains a Functional Nuclear Localization Signal at its N-terminus] [Synopsis DNA Polymerase Beta Contains a Functional Nuclear Localization Signal at its N-terminus] Kirby TW, Gassman NR, Smith CE, Zhao ML, Horton JK, Wilson SH, London RE. December 2016

Dose-Response Assessment of the Dermal Toxicity of Virginia Cedarwood Oil in F344/N Rats and B6C3F1/N Mice [Abstract Dose-Response Assessment of the Dermal Toxicity of Virginia Cedarwood Oil in F344/N Rats and B6C3F1/N Mice] [Synopsis Dose-Response Assessment of the Dermal Toxicity of Virginia Cedarwood Oil in F344/N Rats and B6C3F1/N Mice] Catlin NR, Herbert R, Janardhan K, Hejtmancik MR, Fomby LM, Vallant M, Kissling GE, DeVito MJ. December 2016

Exposure to Fine Particulate Air Pollution Causes Vascular Insulin Resistance by Inducing Pulmonary Oxidative Stress [Abstract Exposure to Fine Particulate Air Pollution Causes Vascular Insulin Resistance by Inducing Pulmonary Oxidative Stress] [Synopsis Exposure to Fine Particulate Air Pollution Causes Vascular Insulin Resistance by Inducing Pulmonary Oxidative Stress] Haberzetti P, O’Toole TE, Bhatnagar A, Conklin DJ. December 2016

Formaldehyde Is a Potent Proteotoxic Stressor Causing Rapid Heat Shock Factor Protein 1 Activation and lys48-linked Polyubiquitination of Proteins [Abstract Formaldehyde Is a Potent Proteotoxic Stressor Causing Rapid Heat Shock Factor Protein 1 Activation and lys48-linked Polyubiquitination of Proteins] [Synopsis Formaldehyde Is a Potent Proteotoxic Stressor Causing Rapid Heat Shock Factor Protein 1 Activation and lys48-linked Polyubiquitination of Proteins] Ortega-Atienza S, Rubis B, McCarthy C, Zhitkovich A. December 2016

Homologous Recombination and Translesion DNA Synthesis Play Critical Roles on Tolerating DNA Damage Caused by Trace Levels of Hexavalent Chromium [Abstract Homologous Recombination and Translesion DNA Synthesis Play Critical Roles on Tolerating DNA Damage Caused by Trace Levels of Hexavalent Chromium] [Synopsis Homologous Recombination and Translesion DNA Synthesis Play Critical Roles on Tolerating DNA Damage Caused by Trace Levels of Hexavalent Chromium] Tian X, Patel K, Ridpath JR, Chen Y, Zhou YH, Neo D, Clement J, Takata M, Takeda S, Sale J, Wright FA, Swenberg JA. December 2016

Order Restricted Inference for Oscillatory Systems for Detecting Rhythmic Signals [Abstract Order Restricted Inference for Oscillatory Systems for Detecting Rhythmic Signals] [Synopsis Order Restricted Inference for Oscillatory Systems for Detecting Rhythmic Signals] Larriba Y, Rueda C, Fernandez MA, Peddada SD. December 2016

Oxidative Guanine Base Damage Regulates Human Telomerase Activity [Abstract Oxidative Guanine Base Damage Regulates Human Telomerase Activity] [Synopsis Oxidative Guanine Base Damage Regulates Human Telomerase Activity] Fouquerel E, Lormand J, Bose A, Lee HT, Kim GS, Li J, Sobol RW, Freudenthal BD, Myong S, Opresko PL. December 2016

The Genomic Landscape of Rapid Repeated Evolutionary Adaptation to Toxic Pollution in Wild Fish [Abstract The Genomic Landscape of Rapid Repeated Evolutionary Adaptation to Toxic Pollution in Wild Fish] [Synopsis The Genomic Landscape of Rapid Repeated Evolutionary Adaptation to Toxic Pollution in Wild Fish] Reid NM, Proestou DA, Clark BW, Warren WC, Colbourne JK, Shaw JR, Karchner SI, Hahn ME, Nacci D, Oleksiak MF, Crawford DL, Whitehead A. December 2016

An Inducible Long Noncoding RNA Amplifies DNA Damage Signaling [Abstract An Inducible Long Noncoding RNA Amplifies DNA Damage Signaling] [Synopsis An Inducible Long Noncoding RNA Amplifies DNA Damage Signaling] [Story An Inducible Long Noncoding RNA Amplifies DNA Damage Signaling] Schmitt AM, Garcia JT, Hung T, Flynn RA, Shen Y, Qu K, Payumo AY, Peres-da-Silva A, Broz DK, Baum R, Guo S, Chen JK, Attardi LD, Chang HY. November 2016

Classification and Clustering Methods for Multiple Environmental Factors in Gene-Environment Interaction: Application to the Multi-Ethnic Study of Atherosclerosis [Abstract Classification and Clustering Methods for Multiple Environmental Factors in Gene-Environment Interaction: Application to the Multi-Ethnic Study of Atherosclerosis] [Synopsis Classification and Clustering Methods for Multiple Environmental Factors in Gene-Environment Interaction: Application to the Multi-Ethnic Study of Atherosclerosis] Ko YA, Mukherjee B, Smith JA, Kardia SL, Alllison M, Diez Roux AV. November 2016

Development and Validation of a Computational Model for Androgen Receptor Activity [Abstract Development and Validation of a Computational Model for Androgen Receptor Activity] [Synopsis Development and Validation of a Computational Model for Androgen Receptor Activity] Kleinstreuer NC, Ceger P, Watt ED, Martin M, Houck K, Browne P, Thomas RS, Casey WM, Dix DJ, Allen D, Sakamuru S, Xia M, Huang R, Judson R. November 2016

Early-Life Farm Exposures and Adult Asthma and Atopy in the Agricultural Lung Health Study [Abstract Early-Life Farm Exposures and Adult Asthma and Atopy in the Agricultural Lung Health Study] [Synopsis Early-Life Farm Exposures and Adult Asthma and Atopy in the Agricultural Lung Health Study] House JS, Wyss AB, Hoppin JA, Richards M, Long S, Umbach DM, Henneberger PK, Beane Freeman LE, Sandler DP, Long O’Connell E, Barker-Cummings C, London SJ. November 2016

Formaldehyde is a Potent Proteotoxic Stressor Causing Rapid Heat Shock Transcription Factor 1 Activation and Lys48-Linked Polyubiquitination of Proteins [Abstract Formaldehyde is a Potent Proteotoxic Stressor Causing Rapid Heat Shock Transcription Factor 1 Activation and Lys48-Linked Polyubiquitination of Proteins] [Synopsis Formaldehyde is a Potent Proteotoxic Stressor Causing Rapid Heat Shock Transcription Factor 1 Activation and Lys48-Linked Polyubiquitination of Proteins] Ortega-Atienza S, Rubis B, McCarthy C, Zhitkovich A. November 2016

Multiwalled Carbon Nanotube Functionalization with High Molecular Weight Hyaluronan Significantly Reduces Pulmonary Injury [Abstract Multiwalled Carbon Nanotube Functionalization with High Molecular Weight Hyaluronan Significantly Reduces Pulmonary Injury] [Synopsis Multiwalled Carbon Nanotube Functionalization with High Molecular Weight Hyaluronan Significantly Reduces Pulmonary Injury] Hussain S, Ji Z, Taylor AJ, DeGraff LM, George M, Tucker CJ, Chang CH, Li R, Bonner JC, Garantziotis S. November 2016

Nanomechanical Mechanism for Lipid Bilayer Damage Induced by Carbon Nanotubes Confined in Intracellular Vesicles [Abstract Nanomechanical Mechanism for Lipid Bilayer Damage Induced by Carbon Nanotubes Confined in Intracellular Vesicles] [Synopsis Nanomechanical Mechanism for Lipid Bilayer Damage Induced by Carbon Nanotubes Confined in Intracellular Vesicles] Zhu W, von dem Bussche A, Yi X, Qiu Y, Wang Z, Weston P, Hurt RH, Kane AB, Gao H. November 2016

A Gata2-Dependent Transcription Network Regulates Uterine Progesterone Responsiveness and Endometrial Function [Abstract A Gata2-Dependent Transcription Network Regulates Uterine Progesterone Responsiveness and Endometrial Function] [Synopsis A Gata2-Dependent Transcription Network Regulates Uterine Progesterone Responsiveness and Endometrial Function] [Story A Gata2-Dependent Transcription Network Regulates Uterine Progesterone Responsiveness and Endometrial Function] Rubel CA, Wu SP, Lin L, Wang T, Lanz RB, Li X, Kommagani R, Franco HL, Camper SA, Tong Q, Jeong JW, Lydon JP, DeMayo FJ. October 2016

Air Pollution Affects Lung Cancer Survival [Abstract Air Pollution Affects Lung Cancer Survival] [Synopsis Air Pollution Affects Lung Cancer Survival] Eckel SP, Cockburn M, Shu YH, Deng H, Lurmann FW, Liu L, Gilliland FD. October 2016

Consumer Product Chemicals in Indoor Dust: A Quantitative Meta-Analysis of U.S. Studies [Abstract Consumer Product Chemicals in Indoor Dust: A Quantitative Meta-Analysis of U.S. Studies] [Synopsis Consumer Product Chemicals in Indoor Dust: A Quantitative Meta-Analysis of U.S. Studies] Mitro SD, Dodson RE, Singla V, Adamkiewicz G, Elmi AF, Tilly MK, Zota AR. October 2016

Differences in the Rate of in Situ Mammary Gland Development and Other Developmental Endpoints in Three Strains of Female Rat Commonly Used in Mammary Carcinogenesis Studies: Implications for Timing of Carcinogen Exposure [Abstract Differences in the Rate of in Situ Mammary Gland Development and Other Developmental Endpoints in Three Strains of Female Rat Commonly Used in Mammary Carcinogenesis Studies: Implications for Timing of Carcinogen Exposure] [Synopsis Differences in the Rate of in Situ Mammary Gland Development and Other Developmental Endpoints in Three Strains of Female Rat Commonly Used in Mammary Carcinogenesis Studies: Implications for Timing of Carcinogen Exposure] Stanko JP, Kissling GE, Chappell VA, Fenton SE. October 2016

Environmental Exposure to Arsenic and Chromium in Children is Associated with Kidney Injury Molecule-1 [Abstract Environmental Exposure to Arsenic and Chromium in Children is Associated with Kidney Injury Molecule-1] [Synopsis Environmental Exposure to Arsenic and Chromium in Children is Associated with Kidney Injury Molecule-1] Cardenas-Gonzalez M, Osorio-Yanez C, Gaspar-Ramirez O, Pavkovic M, Ochoa-Martinez A, Lopez-Ventura D, Medeiros M, Barbier OC, Perez-Maldonado IN, Sabbisetti VS, Bonventre JV, Vaidya VS. October 2016

Exposure to the BPA-substitute Bisphenol S Causes Unique Alterations of Germline Function [Abstract Exposure to the BPA-substitute Bisphenol S Causes Unique Alterations of Germline Function] [Synopsis Exposure to the BPA-substitute Bisphenol S Causes Unique Alterations of Germline Function] Chen Y, Shu L, Qiu Z, Lee DY, Settle SJ, Que Hee S, Telesca D, Yang X, Allard P. October 2016

Mapping Lineage Progression of Somatic Progenitor Cells in the Mouse Fetal Testis [Abstract Mapping Lineage Progression of Somatic Progenitor Cells in the Mouse Fetal Testis] [Synopsis Mapping Lineage Progression of Somatic Progenitor Cells in the Mouse Fetal Testis] Liu C, Rodriguez K, Yao HH. October 2016

Mitochondrial DNA Exhibits Resistance to Induced Point and Deletion Mutations [Abstract Mitochondrial DNA Exhibits Resistance to Induced Point and Deletion Mutations] [Synopsis Mitochondrial DNA Exhibits Resistance to Induced Point and Deletion Mutations] Valente WJ, Ericson NG, Long AS, White PA, Marchetti F, Bielas JH. October 2016

Nop9 is a PUF-like Protein That Prevents Premature Cleavage to Correctly Process Pre-18S rRNA [Abstract Nop9 is a PUF-like Protein That Prevents Premature Cleavage to Correctly Process Pre-18S rRNA] [Synopsis Nop9 is a PUF-like Protein That Prevents Premature Cleavage to Correctly Process Pre-18S rRNA] Zhang J, McCann KL, Qiu C, Gonzalez LE, Baserga SJ, Hall TM. October 2016

Structural Analysis Reveals the Flexible C-Terminus of Nop15 Undergoes Rearrangement To Recognize a Pre-Ribosomal RNA Folding Intermediate [Abstract Structural Analysis Reveals the Flexible C-Terminus of Nop15 Undergoes Rearrangement To Recognize a Pre-Ribosomal RNA Folding Intermediate] [Synopsis Structural Analysis Reveals the Flexible C-Terminus of Nop15 Undergoes Rearrangement To Recognize a Pre-Ribosomal RNA Folding Intermediate] Zhang J, Gonzalez LE, Hall TM. October 2016

The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin Fibroblasts [Abstract The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin Fibroblasts] [Synopsis The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin Fibroblasts] Saini N, Roberts SA, Klimczak LJ, Chan K, Grimm SA, Dai S, Fargo DC, Boyer JC, Kaufmann WK, Taylor JA, Lee E, Cortes-Ciriano I, Park PJ, Schurman SH, Malc EP, Mieczkowski PA, Gordenin DA. October 2016

Ambient Air Pollution Exposures and Risk of Parkinson Disease [Abstract Ambient Air Pollution Exposures and Risk of Parkinson Disease] [Synopsis Ambient Air Pollution Exposures and Risk of Parkinson Disease] Liu R, Young MT, Chen JC, Kaufman JD, Chen H. September 2016

Association Between Unconventional Natural Gas Development in the Marcellus Shale and Asthma Exacerbations [Abstract Association Between Unconventional Natural Gas Development in the Marcellus Shale and Asthma Exacerbations] [Synopsis Association Between Unconventional Natural Gas Development in the Marcellus Shale and Asthma Exacerbations] Rasmussen SG, Ogburn EL, McCormack M, Casey JA, Bandeen-Roche K, Mercer DG, Schwartz BS. September 2016

Differential Activation of a Mouse Estrogen Receptor Beta Isoform (mERBeta2) with Endocrine-Disrupting Chemicals (EDCs) [Abstract Differential Activation of a Mouse Estrogen Receptor Beta Isoform (mERBeta2) with Endocrine-Disrupting Chemicals (EDCs)] [Synopsis Differential Activation of a Mouse Estrogen Receptor Beta Isoform (mERBeta2) with Endocrine-Disrupting Chemicals (EDCs)] Donoghue LJ, Neufeld TI, Li Y, Arao Y, Coons LA, Korach KS. September 2016

High Butter-Fat Diet and Bisphenol A Additively Impair Male Rat Spermatogenesis [Abstract High Butter-Fat Diet and Bisphenol A Additively Impair Male Rat Spermatogenesis] [Synopsis High Butter-Fat Diet and Bisphenol A Additively Impair Male Rat Spermatogenesis] Tarapore P, Hennessy M, Song D, Ying J, Ouyang B, Govindarajah V, Leung YK, Ho SM. September 2016

Hospitalizations Due to Selected Infections Caused By Opportunistic Premise Plumbing Pathogens (OPPP) and Reported Drug Resistance in the United States Older Adult Population in 1991-2006 [Abstract Hospitalizations Due to Selected Infections Caused By Opportunistic Premise Plumbing Pathogens (OPPP) and Reported Drug Resistance in the United States Older Adult Population in 1991-2006] [Synopsis Hospitalizations Due to Selected Infections Caused By Opportunistic Premise Plumbing Pathogens (OPPP) and Reported Drug Resistance in the United States Older Adult Population in 1991-2006] Naumova EN, Liss A, Jagai JS, Behlau I, Griffiths JK. September 2016

INO80 is Required for Oncogenic Transcription and Tumor Growth in Non-Small Cell Lung Cancer [Abstract INO80 is Required for Oncogenic Transcription and Tumor Growth in Non-Small Cell Lung Cancer] [Synopsis INO80 is Required for Oncogenic Transcription and Tumor Growth in Non-Small Cell Lung Cancer] Zhang S, Zhou B, Wang L, Li P, Bennett BD, Snyder R, Garantziotis S, Fargo DC, Cox AD, Chen L, Hu G. September 2016

Integrated Decision Strategies for Skin Sensitization Hazard [Abstract Integrated Decision Strategies for Skin Sensitization Hazard] [Synopsis Integrated Decision Strategies for Skin Sensitization Hazard] Strickland J, Zang Q, Kleinstreuer N, Paris M, Lehmann DM, Choksi N, Matheson J, Jacobs A, Lowit A, Allen D, Casey W. September 2016

Kruppel-like Factor 13 is a Major Mediator of Glucocorticoid Receptor Signaling in Cardiomyocytes and Protects These Cells from DNA Damage and Death [Abstract Kruppel-like Factor 13 is a Major Mediator of Glucocorticoid Receptor Signaling in Cardiomyocytes and Protects These Cells from DNA Damage and Death] [Synopsis Kruppel-like Factor 13 is a Major Mediator of Glucocorticoid Receptor Signaling in Cardiomyocytes and Protects These Cells from DNA Damage and Death] Cruz-Topete D, He B, Xu X, Cidlowski JA. September 2016

MicroRNA-33 Regulates the Innate Immune Response Via ATP Binding Cassette Transporter-mediated Remodeling of Membrane Microdomains [Abstract MicroRNA-33 Regulates the Innate Immune Response Via ATP Binding Cassette Transporter-mediated Remodeling of Membrane Microdomains] [Synopsis MicroRNA-33 Regulates the Innate Immune Response Via ATP Binding Cassette Transporter-mediated Remodeling of Membrane Microdomains] Lai L, Azzam KM, Lin WC, Rai P, Lowe JM, Gabor KA, Madenspacher JH, Aloor JJ, Parks JS, Naar AM, Fessler MB. September 2016

Chromosomal Landscape of UV Damage Formation and Repair at Single-Nucleotide Resolution [Abstract Chromosomal Landscape of UV Damage Formation and Repair at Single-Nucleotide Resolution] [Synopsis Chromosomal Landscape of UV Damage Formation and Repair at Single-Nucleotide Resolution] Mao P, Smerdon MJ, Roberts SA, Wyrick JJ. August 2016

Comparative Toxicity of Organophosphate Flame Retardants and Polybrominated Diphenyl Ethers to Caenorhabditis elegans [Abstract Comparative Toxicity of Organophosphate Flame Retardants and Polybrominated Diphenyl Ethers to Caenorhabditis elegans] [Synopsis Comparative Toxicity of Organophosphate Flame Retardants and Polybrominated Diphenyl Ethers to Caenorhabditis elegans] Behl M, Rice JR, Smith MV, Co CA, Bridge MF, Hsieh JH, Freedman JH, Boyd WA. August 2016

DNA Methylation Score as a Biomarker in Newborns for Sustained Maternal Smoking During Pregnancy [Abstract DNA Methylation Score as a Biomarker in Newborns for Sustained Maternal Smoking During Pregnancy] [Synopsis DNA Methylation Score as a Biomarker in Newborns for Sustained Maternal Smoking During Pregnancy] Reese SE, Zhao S, Wu MC, Joubert BR, Parr CL, Haberg SE, Ueland PM, Nilsen RM, Midttun O, Vollset SE, Peddada SD, Nystad W, London SJ. August 2016

Maternal Folate Intake During Pregnancy and Childhood Asthma in a Population Based Cohort [Abstract Maternal Folate Intake During Pregnancy and Childhood Asthma in a Population Based Cohort] [Synopsis Maternal Folate Intake During Pregnancy and Childhood Asthma in a Population Based Cohort] Parr CL, Magnus MC, Karlstad O, Haugen M, Refsum H, Ueland PM, McCann A, Nafstad P, Haberg SE, Nystad W, London SJ. August 2016

p62, Upregulated During Preneoplasia, Induces Hepatocellular Carcinogenesis by Maintaining Survival of Stressed HCC-initiating Cells [Abstract p62, Upregulated During Preneoplasia, Induces Hepatocellular Carcinogenesis by Maintaining Survival of Stressed HCC-initiating Cells] [Synopsis p62, Upregulated During Preneoplasia, Induces Hepatocellular Carcinogenesis by Maintaining Survival of Stressed HCC-initiating Cells] Umemura A, He F, Taniguchi K, Nakagawa H, Yamachika S, Font-Burgada J, Zhong Z, Subramaniam S, Raghunandan S, Duran A, Linares JF, Reina-Campos M, Umemura S, Valasek MA, Seki E, Yamaguchi K, Koike K, Itoh Y, Diaz-Meco MT, Moscat J, Karin M. August 2016

Perineuronal Nets Suppress Plasticity of Excitatory Synapses on CA2 Pyramidal Neurons [Abstract Perineuronal Nets Suppress Plasticity of Excitatory Synapses on CA2 Pyramidal Neurons] [Synopsis Perineuronal Nets Suppress Plasticity of Excitatory Synapses on CA2 Pyramidal Neurons] Carstens KE, Phillips ML, Pozzo-Miller L, Weinberg RJ, Dudek SM. August 2016

Soy Formula and Epigenetic Modifications: Analysis of Vaginal Epithelial Cells from Infant Girls in the IFED Study [Abstract Soy Formula and Epigenetic Modifications: Analysis of Vaginal Epithelial Cells from Infant Girls in the IFED Study] [Synopsis Soy Formula and Epigenetic Modifications: Analysis of Vaginal Epithelial Cells from Infant Girls in the IFED Study] Harlid S, Adgent M, Jefferson WN, Panduri V, Umbach DM, Xu Z, Stallings VA, Williams CJ, Rogan WJ, Taylor JA. August 2016

A Polymorphic Antioxidant Response Element Links NRF2/sMAF Binding to Enhanced MAPT Expression and Reduced Risk of Parkinsonian Disorders [Abstract A Polymorphic Antioxidant Response Element Links NRF2/sMAF Binding to Enhanced MAPT Expression and Reduced Risk of Parkinsonian Disorders] [Synopsis A Polymorphic Antioxidant Response Element Links NRF2/sMAF Binding to Enhanced MAPT Expression and Reduced Risk of Parkinsonian Disorders] Wang X, Campbell MR, Lacher SE, Cho HY, Wan M, Crowl CL, Chorley BN, Bond GL, Kleeberger SR, Slattery M, Bell DA. July 2016

Copper-induced Structural Conversion Templates Prion Protein Oligomerization and Neurotoxicity [Abstract Copper-induced Structural Conversion Templates Prion Protein Oligomerization and Neurotoxicity] [Synopsis Copper-induced Structural Conversion Templates Prion Protein Oligomerization and Neurotoxicity] Yen CF, Harischandra DS, Kanthasamy A, Sivasankar S. July 2016

Dioxin-like Pollutants Increase Hepatic Flavin Containing Monooxygenase (FMO3) Expression to Promote Synthesis of the Pro-Atherogenic Nutrient Biomarker Trimethylamine N-oxide from Dietary Precursors [Abstract Dioxin-like Pollutants Increase Hepatic Flavin Containing Monooxygenase (FMO3) Expression to Promote Synthesis of the Pro-Atherogenic Nutrient Biomarker Trimethylamine N-oxide from Dietary Precursors] [Synopsis Dioxin-like Pollutants Increase Hepatic Flavin Containing Monooxygenase (FMO3) Expression to Promote Synthesis of the Pro-Atherogenic Nutrient Biomarker Trimethylamine N-oxide from Dietary Precursors] Petriello MC, Hoffman JB, Sunkara M, Wahlang B, Perkins JT, Morris AJ, Hennig B. July 2016

Exposure to the BPA-Substituted Bisphenol S Causes Unique Alterations of Germline Function [Abstract Exposure to the BPA-Substituted Bisphenol S Causes Unique Alterations of Germline Function] [Synopsis Exposure to the BPA-Substituted Bisphenol S Causes Unique Alterations of Germline Function] Chen Y, Shu L, Qiu Z, Lee DY, Settle SJ, Que Hee S, Telesca D, Yang X, Allard P. July 2016

Heme Dynamics and Trafficking Factors Revealed by Genetically Encoded Fluorescent Heme Sensors [Abstract Heme Dynamics and Trafficking Factors Revealed by Genetically Encoded Fluorescent Heme Sensors] [Synopsis Heme Dynamics and Trafficking Factors Revealed by Genetically Encoded Fluorescent Heme Sensors] Hanna DA, Harvey RM, Martinez-Guzman O, Yuan X, Chandrasekharan B, Raju G, Outten FW, Hamza I, Reddi AR. July 2016

Neurons and Astroglia Govern Microglial Endotoxin Tolerance Through Macrophage Colony-Stimulating Factor Receptor-Mediated ERK1/2 Signals [Abstract Neurons and Astroglia Govern Microglial Endotoxin Tolerance Through Macrophage Colony-Stimulating Factor Receptor-Mediated ERK1/2 Signals] [Synopsis Neurons and Astroglia Govern Microglial Endotoxin Tolerance Through Macrophage Colony-Stimulating Factor Receptor-Mediated ERK1/2 Signals] Chu CH, Wang S, Li CL, Chen SH, Hu CF, Chung YL, Chen SL, Wang Q, Lu RB, Gao HM, Hong JS. July 2016

Noncanonical Autophagy Inhibits the Autoinflammatory, Lupus-like Responses to Dying Cells [Abstract Noncanonical Autophagy Inhibits the Autoinflammatory, Lupus-like Responses to Dying Cells] [Synopsis Noncanonical Autophagy Inhibits the Autoinflammatory, Lupus-like Responses to Dying Cells] Martinez J, Cunha LD, Park S, Yang M, Lu Q, Orchard R, Li QZ, Yan M, Janke L, Guy C, Linkermann A, Virgin HW, Green DR. July 2016

Pesticides Are Associated With Allergic and Non-Allergic Wheeze Among Male Farmers [Abstract Pesticides Are Associated With Allergic and Non-Allergic Wheeze Among Male Farmers] [Synopsis Pesticides Are Associated With Allergic and Non-Allergic Wheeze Among Male Farmers] Hoppin JA, Umbach DM, Long S, London SJ, Henneberger PK, Blair A, Alavanja M, Beane Freeman LE, Sandler DP. July 2016

The Next Generation of Risk Assessment Multiyear Study — Highlights of Findings, Applications to Risk Assessment, and Future Directions [Abstract The Next Generation of Risk Assessment Multiyear Study — Highlights of Findings, Applications to Risk Assessment, and Future Directions] [Synopsis The Next Generation of Risk Assessment Multiyear Study — Highlights of Findings, Applications to Risk Assessment, and Future Directions] Cote I, Andersen ME, Ankley GT, Barone S, Birnbaum LS, Boekelheide K, Bois FY, Burgoon LD, Chiu WA, Crawford-Brown D, Crofton KM, DeVito M, Devlin RB, Edwards SW, Guyton KZ, Hattis D, Judson RS, Knight D, Krewski D, Lambert J, Maull EA, Mendrick D, Paoli GM, Patel CJ, Perkins EJ, Poje G, Portier CJ, Rusyn I, Schulte PA, Simeonov A, Smith MT, Thayer KA, Thomas RS, Thomas R, Tice RR, Vandenberg JJ, Villeneuve DL, Wesselkamper S, Whelan M, Whittaker C, White R, Xia M, Yauk C, Zeise L, Zhao J, DeWoskin RS. July 2016

Advancing Toxicology Research Using In Vivo High Throughput Toxicology With Small Fish Models [Abstract Advancing Toxicology Research Using In Vivo High Throughput Toxicology With Small Fish Models] [Synopsis Advancing Toxicology Research Using In Vivo High Throughput Toxicology With Small Fish Models] Planchart A, Mattingly CJ, Allen D, Ceger P, Casey W, Hinton D, Kanungo J, Kullman SW, Tal T, Bondesson M, Burgess SM, Sullivan C, Kim C, Behl M, Padilla S, Reif DM, Tanguay RL, Hamm J. June 2016

Epigenome-wide Tumor DNA Methylation Profiling Identifies Novel Prognostic Biomarkers of Metastatic-lethal Progression in Men with Clinically Localized Prostate Cancer [Abstract Epigenome-wide Tumor DNA Methylation Profiling Identifies Novel Prognostic Biomarkers of Metastatic-lethal Progression in Men with Clinically Localized Prostate Cancer] [Synopsis Epigenome-wide Tumor DNA Methylation Profiling Identifies Novel Prognostic Biomarkers of Metastatic-lethal Progression in Men with Clinically Localized Prostate Cancer] [Story Epigenome-wide Tumor DNA Methylation Profiling Identifies Novel Prognostic Biomarkers of Metastatic-lethal Progression in Men with Clinically Localized Prostate Cancer] Zhao S, Geybels MS, Leonardson A, Rubicz R, Kolb S, Yan Q, Klotzle B, Bibikova M, Hurtado-Coll A, Troyer D, Lance R, Lin D, Wright JL, Ostrander EA, Fan JB, Feng Z, Stanford JL. June 2016

INO80 Governs Superenhancer-Mediated Oncogenic Transcription and Tumor Growth in Melanoma [Abstract INO80 Governs Superenhancer-Mediated Oncogenic Transcription and Tumor Growth in Melanoma] [Synopsis INO80 Governs Superenhancer-Mediated Oncogenic Transcription and Tumor Growth in Melanoma] Zhou B, Wang L, Zhang S, Bennett BD, He F, Zhang Y, Xiong C, Han L, Diao L, Li P, Fargo DC, Cox AD, Hu G. June 2016

Key Characteristics of Carcinogens as a Basis for Organizing Data on Mechanisms of Carcinogenesis [Abstract Key Characteristics of Carcinogens as a Basis for Organizing Data on Mechanisms of Carcinogenesis] [Synopsis Key Characteristics of Carcinogens as a Basis for Organizing Data on Mechanisms of Carcinogenesis] Smith MT, Guyton KZ, Gibbons CF, Fritz JM, Portier CJ, Rusyn I, DeMarini DM, Caldwell JC, Kavlock RJ Lambert PF, Hecht SS, Bucher JR, Stewart BW, Baan RA, Cogliano VJ, Straif K. June 2016

Neurotoxicity of the Parkinson’s Disease-Associated Pesticide Ziram Is Synuclein-Dependent in Zebrafish Embryos [Abstract Neurotoxicity of the Parkinson’s Disease-Associated Pesticide Ziram Is Synuclein-Dependent in Zebrafish Embryos] [Synopsis Neurotoxicity of the Parkinson’s Disease-Associated Pesticide Ziram Is Synuclein-Dependent in Zebrafish Embryos] Lulla A, Barnhill L, Bitan G, Ivanova MI, Nguyen B, O’Donnell K, Stahl MC, Yamashiro C, Klarner FG, Schrader T, Sagasti A, Bronstein JM. June 2016

Preferential Epigenetic Programming of Estrogen Response After In Utero Xenoestrogen (Bisphenol-A) Exposure [Abstract Preferential Epigenetic Programming of Estrogen Response After In Utero Xenoestrogen (Bisphenol-A) Exposure] [Synopsis Preferential Epigenetic Programming of Estrogen Response After In Utero Xenoestrogen (Bisphenol-A) Exposure] Jorgensen EM, Alderman MH 3rd, Taylor HS. June 2016

Recombinase-dependent Mouse Lines for Chemogenetic Activation of Genetically Defined Cell Types [Abstract Recombinase-dependent Mouse Lines for Chemogenetic Activation of Genetically Defined Cell Types] [Synopsis Recombinase-dependent Mouse Lines for Chemogenetic Activation of Genetically Defined Cell Types] Sciolino NR, Plummer NW, Chen YW, Alexander GM, Robertson SD, Dudek SM, McElligott ZA, Jensen P. June 2016

Rheumatoid Arthritis in Agricultural Health Study Spouses: Associations with Pesticides and Other Farm Exposures [Abstract Rheumatoid Arthritis in Agricultural Health Study Spouses: Associations with Pesticides and Other Farm Exposures] [Synopsis Rheumatoid Arthritis in Agricultural Health Study Spouses: Associations with Pesticides and Other Farm Exposures] Parks CG, Hoppin JA, DeRoos AJ, Costenbader KH, Alavanja MC, Sandler DP. June 2016

Transcription Factor GLIS3: A New and Critical Regulator of Postnatal Stages of Mouse Spermatogenesis [Abstract Transcription Factor GLIS3: A New and Critical Regulator of Postnatal Stages of Mouse Spermatogenesis] [Synopsis Transcription Factor GLIS3: A New and Critical Regulator of Postnatal Stages of Mouse Spermatogenesis] Kang HS, Chen LY, Lichti-Kaiser K, Liao G, Gerrish K, Bortner CD, Yao HH, Eddy EM, Jetten AM. June 2016

A Chemical-Biological Similarity-Based Grouping of Complex Substances as a Prototype Approach for Evaluating Chemical Alternatives [Abstract A Chemical-Biological Similarity-Based Grouping of Complex Substances as a Prototype Approach for Evaluating Chemical Alternatives] [Synopsis A Chemical-Biological Similarity-Based Grouping of Complex Substances as a Prototype Approach for Evaluating Chemical Alternatives] Grimm FA, Iwata Y, Sirenko O, Chappell GA, Wright FA, Reif DM, Braisted J, Gerhold DL, Yeakley JM, Shepard P, Seligmann B, Roy T, Boogaard PJ, Ketekslegers HB, Rohde AM, Rusyn I. May 2016

Association Between Air Pollution and Coronary Artery Calcification Within Six Metropolitan Areas in the USA (the Multi-Ethnic Study of Atherosclerosis and Air Pollution): A Longitudinal Cohort Study [Abstract Association Between Air Pollution and Coronary Artery Calcification Within Six Metropolitan Areas in the USA (the Multi-Ethnic Study of Atherosclerosis and Air Pollution): A Longitudinal Cohort Study] [Synopsis Association Between Air Pollution and Coronary Artery Calcification Within Six Metropolitan Areas in the USA (the Multi-Ethnic Study of Atherosclerosis and Air Pollution): A Longitudinal Cohort Study] Kaufman JD, Adar SD, Barr RG, Budoff M, Burke GL, Curl CL, Daviglus ML, Roux AV, Gassett AJ, Jacobs DR Jr, Kronmal R, Larson TV, Navas-Acien A, Olives C, Sampson PD, Sheppard L, Siscovick DS, Stein JH, Szpiro AA, Watson KE. May 2016

Brg1 Enables Rapid Growth of the Early Embryo by Suppressing Genes That Regulate Apoptosis and Cell Growth Arrest [Abstract Brg1 Enables Rapid Growth of the Early Embryo by Suppressing Genes That Regulate Apoptosis and Cell Growth Arrest] [Synopsis Brg1 Enables Rapid Growth of the Early Embryo by Suppressing Genes That Regulate Apoptosis and Cell Growth Arrest] Singh AP, Foley JF, Rubino M, Boyle MC, Tandon A, Shah R, Archer TK. May 2016

DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis [Abstract DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis] [Synopsis DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis] Joubert BR, Felix JF, Yousefi P, Bakulski KM, Just AC, Breton C, Reese S, Markunas CA, Richmond RC, Xu C-J, Kupers LK, Oh SS, Hoyo C, Gruzieva O, Soderhall C, Salas LA, Baiz N, Zhang H, Lepeule J, Ruiz C, Ligthart S, Wang T, Taylor JA, Duijts L, Sharp GC, Jankipersadsing SA, Nilsen RM, Vaez A, Fallin MD, Hu D, Litonjua AA, Fuemmeler BF, Huen K, Kere J, Kull I, Munthe-Kaas MC, Gehring U, Bustamante M, Saurel-Coubizolles MJ, Quraishi BM, Ren J, Tost J, Gonzalez JR, Peters MJ, Haberg SE, Xu Z, van Meurs JB, Gaunt TR, Kerkhof M, Corpeleijn E, Feinberg AP, Eng C, Baccarelli AA, Neelon SEB, Bradman A, Merid K, Bergstrom A, Herceg Z, Hernandez-Vargas H, Brunekreef B, Pinart M, Heude B, Ewart S, Yao J, Lemonnier N, Franco OH Wu MC, Hofman A, McArdle W, Van der Vlies P, Falahi F, Gillman MW, Barcellos LF, Kumar A, Wickman M, Guerra S, Charles M-A, Holloway J, Auffray C, Tiemeier HW, Smith GD, Postma D, Hivert M-F, Eskenazi B, Vrijheid M, Arshad H, Anto JM, Dehghan A, Karmaus W, Annesi-Maesano I, Sunyer J, Ghantous A, Pershagen G, Holland N, Murphy SK, DeMeo DL, Burchard EG, Ladd-Acosta C, Snieder H, Nystad W, Koppelman GH, Relton CL, Jaddoe VWV, Wilcox A, Melen E, London SJ. May 2016

Generating Gene Ontology-Disease Inferences to Explore Mechanisms of Human Disease at the Comparative Toxicogenomics Database [Abstract Generating Gene Ontology-Disease Inferences to Explore Mechanisms of Human Disease at the Comparative Toxicogenomics Database] [Synopsis Generating Gene Ontology-Disease Inferences to Explore Mechanisms of Human Disease at the Comparative Toxicogenomics Database] Davis AP, Wiegers TC, King BL, Wiegers J, Grondin CJ, Sciaky D, Johnson RJ, Mattingly CJ. May 2016

Noncanonical Autophagy Inhibits the Autoinflammatory, Lupus-Like Response to Dying Cells [Abstract Noncanonical Autophagy Inhibits the Autoinflammatory, Lupus-Like Response to Dying Cells] [Synopsis Noncanonical Autophagy Inhibits the Autoinflammatory, Lupus-Like Response to Dying Cells] Martinez J, Cunha LD, Park S, Yang M, Lu Q, Orchard R, Li QZ, Yan M, Janke L, Guy C, Linkermann A, Virgin HW, Green DR. May 2016

Reducing Emergency Department Visits for Acute Gastrointestinal Illnesses in North Carolina (USA) by Extending Community Water Service [Abstract Reducing Emergency Department Visits for Acute Gastrointestinal Illnesses in North Carolina (USA) by Extending Community Water Service] [Synopsis Reducing Emergency Department Visits for Acute Gastrointestinal Illnesses in North Carolina (USA) by Extending Community Water Service] DeFelice NB, Johnston JE, Gibson JM. May 2016

Reinterpreting the Best Biomarker of Oxidative Stress: The 8-iso-prostaglandin F2alpha/Prostaglandin F2alpha Ratio Shows Complex Origins of Lipid Peroxidation Biomarkers in Animal Models [Abstract Reinterpreting the Best Biomarker of Oxidative Stress: The 8-iso-prostaglandin F2alpha/Prostaglandin F2alpha Ratio Shows Complex Origins of Lipid Peroxidation Biomarkers in Animal Models] [Synopsis Reinterpreting the Best Biomarker of Oxidative Stress: The 8-iso-prostaglandin F2alpha/Prostaglandin F2alpha Ratio Shows Complex Origins of Lipid Peroxidation Biomarkers in Animal Models] Van’t Erve TJ, Lih FB, Jelsema C, Deterding LJ, Eling TE, Mason RP, Kadiiska MB. May 2016

Reversal of DNA Damage Induced Topoisomerase 2 DNA-Protein Crosslinks by Tdp2 [Abstract Reversal of DNA Damage Induced Topoisomerase 2 DNA-Protein Crosslinks by Tdp2] [Synopsis Reversal of DNA Damage Induced Topoisomerase 2 DNA-Protein Crosslinks by Tdp2] Schellenberg MJ, Perera L, Strom CN, Waters CA, Monian B, Appel CD, Vilas CK, Williams JG, Ramsden DA, Williams RS. May 2016

Structural Characterization of the Virulence Factor Sda1 Nuclease from Streptococcus pyogenes [Abstract Structural Characterization of the Virulence Factor Sda1 Nuclease from Streptococcus pyogenes] [Synopsis Structural Characterization of the Virulence Factor Sda1 Nuclease from Streptococcus pyogenes] Moon AF, Krahn JM, Lu X, Cuneo MJ, Pedersen LC. May 2016

Association of Changes in Air Quality With Bronchitic Symptoms in Children in California, 1993-2012 [Abstract Association of Changes in Air Quality With Bronchitic Symptoms in Children in California, 1993-2012] [Synopsis Association of Changes in Air Quality With Bronchitic Symptoms in Children in California, 1993-2012] Berhane K, Chang CC, McConnell R, Gauderman WJ, Avol E, Rapapport E, Urman R, Lurmann F, Gilliland F. April 2016

Combined Effects of High-Dose Bisphenol A and Oxidizing Agent (KBrO3) on Cellular Microenvironment, Gene Expression, and Chromatin Structure of Ku70-deficient Mouse Embryonic Fibroblasts [Abstract Combined Effects of High-Dose Bisphenol A and Oxidizing Agent (KBrO3) on Cellular Microenvironment, Gene Expression, and Chromatin Structure of Ku70-deficient Mouse Embryonic Fibroblasts] [Synopsis Combined Effects of High-Dose Bisphenol A and Oxidizing Agent (KBrO3) on Cellular Microenvironment, Gene Expression, and Chromatin Structure of Ku70-deficient Mouse Embryonic Fibroblasts] Gassman NR, Coskun E, Jaruga P, Dizdaroglu M, Wilson SH. April 2016

Deficiency of the Placenta- and Yolk Sac-Specific Tristetraprolin Family Member ZFP36L3 Identifies Likely mRNA Targets and an Unexpected Link to Placental Iron Metabolism [Abstract Deficiency of the Placenta- and Yolk Sac-Specific Tristetraprolin Family Member ZFP36L3 Identifies Likely mRNA Targets and an Unexpected Link to Placental Iron Metabolism] [Synopsis Deficiency of the Placenta- and Yolk Sac-Specific Tristetraprolin Family Member ZFP36L3 Identifies Likely mRNA Targets and an Unexpected Link to Placental Iron Metabolism] Stumpo DJ, Trempus CS, Tucker CJ, Huang W, Li L, Kluckman K, Bortner DM, Blackshear PJ. April 2016

Effects of Combined Tristetraprolin/Tumor Necrosis Factor Receptor Deficiency on the Splenic Transcriptome [Abstract Effects of Combined Tristetraprolin/Tumor Necrosis Factor Receptor Deficiency on the Splenic Transcriptome] [Synopsis Effects of Combined Tristetraprolin/Tumor Necrosis Factor Receptor Deficiency on the Splenic Transcriptome] Patial S, Stumpo DJ, Young WS 3rd, Ward JM, Flake GP, Blackshear PJ. April 2016

Exposure to Greenness and Mortality in a Nationwide Prospective Cohort Study of Women [Abstract Exposure to Greenness and Mortality in a Nationwide Prospective Cohort Study of Women] [Synopsis Exposure to Greenness and Mortality in a Nationwide Prospective Cohort Study of Women] James P, Hart JE, Banay RF, Laden F. April 2016

Global Marine Pollutants Inhibit P-glycoprotein: Environmental Levels, Inhibitory Effects, and Cocrystal Structure [Abstract Global Marine Pollutants Inhibit P-glycoprotein: Environmental Levels, Inhibitory Effects, and Cocrystal Structure] [Synopsis Global Marine Pollutants Inhibit P-glycoprotein: Environmental Levels, Inhibitory Effects, and Cocrystal Structure] Nicklisch SC, Rees SD, McGrath AP, Gokirmak T, Bonito LT, Vermeer LM, Cregger C, Loewen G, Sandin S, Chang G, Hamdoun A. April 2016

Role of p53, Mitochondrial DNA Deletions, and Paternal Age in Autism: A Case-Control Study [Abstract Role of p53, Mitochondrial DNA Deletions, and Paternal Age in Autism: A Case-Control Study] [Synopsis Role of p53, Mitochondrial DNA Deletions, and Paternal Age in Autism: A Case-Control Study] Wong S, Napoli E, Krakowiak P, Tassone F, Hertz-Picciotto I, Giulivi C. April 2016

Targeting the Gdnf Gene in Peritubular Myoid Cells Disrupts Undifferentiated Spermatogonial Cell Development [Abstract Targeting the Gdnf Gene in Peritubular Myoid Cells Disrupts Undifferentiated Spermatogonial Cell Development] [Synopsis Targeting the Gdnf Gene in Peritubular Myoid Cells Disrupts Undifferentiated Spermatogonial Cell Development] Chen LY, Willis WD, Eddy EM. April 2016

Associations of Perfluoroalkyl Substances (PFAS) with Lower Birth Weight: An Evaluation of Potential Confounding by Glomerular Filtration Rate Using a Physiologically Based Pharmacokinetic Model (PBPK) [Abstract Associations of Perfluoroalkyl Substances (PFAS) with Lower Birth Weight: An Evaluation of Potential Confounding by Glomerular Filtration Rate Using a Physiologically Based Pharmacokinetic Model (PBPK)] [Synopsis Associations of Perfluoroalkyl Substances (PFAS) with Lower Birth Weight: An Evaluation of Potential Confounding by Glomerular Filtration Rate Using a Physiologically Based Pharmacokinetic Model (PBPK)] Verner MA, Loccisano AE, Morken NH, Yoon M, Wu H, McDougall R, Maisonet M, Marcus M, Kishi R, Miyashita C, Chen MH, Hsieh WS, Andersen ME, Clewell HJ, Longnecker MP. March 2016

Chemical Reactivity and Respiratory Toxicity of the Alpha-Diketone Flavoring Agents: 2,3-Butanedione, 2,3-Pentanedione, and 2,3-Hexanedione [Abstract Chemical Reactivity and Respiratory Toxicity of the Alpha-Diketone Flavoring Agents: 2,3-Butanedione, 2,3-Pentanedione, and 2,3-Hexanedione] [Synopsis Chemical Reactivity and Respiratory Toxicity of the Alpha-Diketone Flavoring Agents: 2,3-Butanedione, 2,3-Pentanedione, and 2,3-Hexanedione] Morgan DL, Jokinen MP, Johnson CL, Price HC, Gwinn WM, Bousquet RW, Flake GP. March 2016

Effects of Low Level Lead Exposure on Associative Learning and Memory in the Rat: Influences of Sex and Developmental Timing of Exposure [Abstract Effects of Low Level Lead Exposure on Associative Learning and Memory in the Rat: Influences of Sex and Developmental Timing of Exposure] [Synopsis Effects of Low Level Lead Exposure on Associative Learning and Memory in the Rat: Influences of Sex and Developmental Timing of Exposure] Anderson DW, Mettil W, Schneider JS. March 2016

Gene Deficiency and Pharmacological Inhibition of Soluble Epoxide Hydrolase Confers Resilience to Repeated Social Defeat Stress [Abstract Gene Deficiency and Pharmacological Inhibition of Soluble Epoxide Hydrolase Confers Resilience to Repeated Social Defeat Stress] [Synopsis Gene Deficiency and Pharmacological Inhibition of Soluble Epoxide Hydrolase Confers Resilience to Repeated Social Defeat Stress] Ren Q, Ma M, Ishima T, Morisseau C, Yang J, Wagner KM, Zhang JC, Yang C, Yao W, Dong C, Han M, Hammock BD, Hashimoto K. March 2016

Histology Atlas of the Developing Mouse Hepatobiliary Hemolymphatic Vascular System with Emphasis on Embryonic Days 11.5-18.5 and Early Postnatal Development [Abstract Histology Atlas of the Developing Mouse Hepatobiliary Hemolymphatic Vascular System with Emphasis on Embryonic Days 11.5-18.5 and Early Postnatal Development] [Synopsis Histology Atlas of the Developing Mouse Hepatobiliary Hemolymphatic Vascular System with Emphasis on Embryonic Days 11.5-18.5 and Early Postnatal Development] Swartley OM, Foley JF, Livingston DP 3rd, Cullen JM, Elmore SA. March 2016

Long-term Air Pollution Exposure and Blood Pressure in the Sister Study [Abstract Long-term Air Pollution Exposure and Blood Pressure in the Sister Study] [Synopsis Long-term Air Pollution Exposure and Blood Pressure in the Sister Study] Chan SH, Van Hee VC, Bergen S, Szpiro AA, DeRoo LA, London SJ, Marshall JD, Kaufman JD, Sandler DP. March 2016

Neurite Outgrowth in Human Induced Pluripotent Stem Cell-Derived Neurons As a High-Throughput Screen For Developmental Neurotoxicity or Neurotoxicity [Abstract Neurite Outgrowth in Human Induced Pluripotent Stem Cell-Derived Neurons As a High-Throughput Screen For Developmental Neurotoxicity or Neurotoxicity] [Synopsis Neurite Outgrowth in Human Induced Pluripotent Stem Cell-Derived Neurons As a High-Throughput Screen For Developmental Neurotoxicity or Neurotoxicity] Ryan KR, Sirenko O, Parham F, Hsieh JH, Cromwell EF, Tice RR, Behl M. March 2016

Particulate Air Pollution Exposure and Expression of Viral and Human MicroRNAs in Blood: The Beijing Truck Driver Air Pollution Study [Abstract Particulate Air Pollution Exposure and Expression of Viral and Human MicroRNAs in Blood: The Beijing Truck Driver Air Pollution Study] [Synopsis Particulate Air Pollution Exposure and Expression of Viral and Human MicroRNAs in Blood: The Beijing Truck Driver Air Pollution Study] Hou L, Barupal J, Zhang W, Zheng Y, Liu L, Zhang X, Dou C, McCracken JP, Diaz A, Motta V, Sanchez-Guerra M, Wolf KR, Bertazzi PA, Schwartz JD, Wang S, Baccarelli AA. March 2016

Relation Between In Utero Arsenic Exposure and Birth Outcomes in a Cohort of Mothers and Their Newborns From New Hampshire [Abstract Relation Between In Utero Arsenic Exposure and Birth Outcomes in a Cohort of Mothers and Their Newborns From New Hampshire] [Synopsis Relation Between In Utero Arsenic Exposure and Birth Outcomes in a Cohort of Mothers and Their Newborns From New Hampshire] Gilbert-Diamond D, Emond JA, Baker ER, Korrick SA, Karagas MR. March 2016

Active Sampling Device for Determining Pollutants in Surface and Pore Water — the In Situ Sampler for Biphasic Water Monitoring [Abstract Active Sampling Device for Determining Pollutants in Surface and Pore Water — the In Situ Sampler for Biphasic Water Monitoring] [Synopsis Active Sampling Device for Determining Pollutants in Surface and Pore Water — the In Situ Sampler for Biphasic Water Monitoring] Supowit SD, Roll IB, Dang VD, Kroll KJ, Denslow ND, Halden RU. February 2016

An Embryonic Atrazine Exposure Results in Reproductive Dysfunction in Adult Zebrafish and Morphological Alterations in Their Offspring [Abstract An Embryonic Atrazine Exposure Results in Reproductive Dysfunction in Adult Zebrafish and Morphological Alterations in Their Offspring] [Synopsis An Embryonic Atrazine Exposure Results in Reproductive Dysfunction in Adult Zebrafish and Morphological Alterations in Their Offspring] Wirbisky SE, Weber GJ, Sepulveda MS, Lin TL, Jannasch AS, Freeman JL. February 2016

Association of Seafood Consumption, Brain Mercury Level, and APOE Eplison4 Status With Brain Neuropathology in Older Adults [Abstract Association of Seafood Consumption, Brain Mercury Level, and APOE Eplison4 Status With Brain Neuropathology in Older Adults] [Synopsis Association of Seafood Consumption, Brain Mercury Level, and APOE Eplison4 Status With Brain Neuropathology in Older Adults] Morris MC, Brockman J, Schneider JA, Wang Y, Bennett DA, Tangney CC, van de Rest O. February 2016

Decreased Lung Function in 7-Year-Old Children with Early-Life Organophosphate Exposure [Abstract Decreased Lung Function in 7-Year-Old Children with Early-Life Organophosphate Exposure] [Synopsis Decreased Lung Function in 7-Year-Old Children with Early-Life Organophosphate Exposure] Raanan R, Balmes JR, Harley KG, Gunier RB, Magzamen S, Bradman A, Eskenazi B. February 2016

Enhanced Stability of Tristetraprolin mRNA Protects Mice Against Immune-Mediated Inflammatory Pathologies [Abstract Enhanced Stability of Tristetraprolin mRNA Protects Mice Against Immune-Mediated Inflammatory Pathologies] [Synopsis Enhanced Stability of Tristetraprolin mRNA Protects Mice Against Immune-Mediated Inflammatory Pathologies] [Story Enhanced Stability of Tristetraprolin mRNA Protects Mice Against Immune-Mediated Inflammatory Pathologies] Patial S, Curtis AD 2nd, Lai WS, Stumpo DJ, Hill GD, Flake GP, Mannie MD, Blackshear PJ. February 2016

Expanding the Power of Recombinase-based Labeling to Uncover Cellular Diversity [Abstract Expanding the Power of Recombinase-based Labeling to Uncover Cellular Diversity] [Synopsis Expanding the Power of Recombinase-based Labeling to Uncover Cellular Diversity] Plummer NW, Evsyukova IY, Robertson SD, de Marchena J, Tucker CJ, Jensen P. February 2016

GATA3-Dependent Cellular Reprogramming Requires Activation-Domain Dependent Recruitment of a Chromatin Remodeler [Abstract GATA3-Dependent Cellular Reprogramming Requires Activation-Domain Dependent Recruitment of a Chromatin Remodeler] [Synopsis GATA3-Dependent Cellular Reprogramming Requires Activation-Domain Dependent Recruitment of a Chromatin Remodeler] Takaku M, Grimm SA, Shimbo T, Perera L, Menafra R, Stunnenberg HG, Archer TK, Machida S, Kurumizaka H, Wade PA. February 2016

Maternal Plasma Folate Impacts Differential DNA Methylation in an Epigenome-Wide Meta-Analysis of Newborns [Abstract Maternal Plasma Folate Impacts Differential DNA Methylation in an Epigenome-Wide Meta-Analysis of Newborns] [Synopsis Maternal Plasma Folate Impacts Differential DNA Methylation in an Epigenome-Wide Meta-Analysis of Newborns] Joubert BR, den Dekker HT, Felix JF, Bohlin J, Ligthart S, Beckett E, Tiemeier H, van Meurs JB, Uitterlinden AG, Hofman A, Haberg SE, Reese SE, Peters MJ, Kulle Andreassen B, Steegers EA, Nilsen RM, Vollset SE, Midttun O, Ueland PM, Franco OH, Deghan A, de Jongste JC, Wu MC, Wang T, Peddada SD, Jaddoe VW, Nystad W, Duijts L, London SJ. February 2016

Methods for Individualized Determination of Methylmercury Elimination Rate and De-Methylation Status in Humans Following Fish Consumption [Abstract Methods for Individualized Determination of Methylmercury Elimination Rate and De-Methylation Status in Humans Following Fish Consumption] [Synopsis Methods for Individualized Determination of Methylmercury Elimination Rate and De-Methylation Status in Humans Following Fish Consumption] Rand MD, Vorojeikina D, van Wijngaarden E, Jackson BP, Scrimale T, Zareba G, Love TM, Myers GJ, Watson GE. February 2016

The Association of Maternal Obesity and Diabetes With Autism and Other Developmental Disabilities [Abstract The Association of Maternal Obesity and Diabetes With Autism and Other Developmental Disabilities] [Synopsis The Association of Maternal Obesity and Diabetes With Autism and Other Developmental Disabilities] Li M, Fallin MD, Riley A, Landa R, Walker SO, Silverstein M, Caruso D, Pearson C, Kiang S, Dahm JL, Hong X, Wang G, Wang MC, Zuckerman B, Wang X. February 2016

Unfolding the HIV-1 Reverse Transcriptase RNase H Domain — How to Lose a Molecular Tug-Of-War [Abstract Unfolding the HIV-1 Reverse Transcriptase RNase H Domain — How to Lose a Molecular Tug-Of-War] [Synopsis Unfolding the HIV-1 Reverse Transcriptase RNase H Domain — How to Lose a Molecular Tug-Of-War] Zheng X, Pedersen LC, Gabel SA, Mueller GA, DeRose EF, London RE. February 2016

Prenatal Perfluoroalkyl Substance Exposure and Child Adiposity at 8 Years of Age: The HOME Study [Abstract Prenatal Perfluoroalkyl Substance Exposure and Child Adiposity at 8 Years of Age: The HOME Study] [Synopsis Prenatal Perfluoroalkyl Substance Exposure and Child Adiposity at 8 Years of Age: The HOME Study] Braun JM, Chen A, Romano ME, Calafat AM, Webster GM, Yolton K, Lanphear BP. January 2016

Quantitative Profiling of Protein S-Glutathionylation Reveals Redox-dependent Regulation of Macrophage Function During Nanoparticle-induced Oxidative Stress [Abstract Quantitative Profiling of Protein S-Glutathionylation Reveals Redox-dependent Regulation of Macrophage Function During Nanoparticle-induced Oxidative Stress] [Synopsis Quantitative Profiling of Protein S-Glutathionylation Reveals Redox-dependent Regulation of Macrophage Function During Nanoparticle-induced Oxidative Stress] Duan J, Kodali VK, Gaffrey MJ, Guo J, Chu RK, Camp DG, Smith RD, Thrall BD, Qian WJ. January 2016

Renal Cell Carcinomas in Vinylidene Chloride-exposed Male B6C3F1 Mice Are Characterized by Oxidative Stress and TP53 Pathway Dysregulation [Abstract Renal Cell Carcinomas in Vinylidene Chloride-exposed Male B6C3F1 Mice Are Characterized by Oxidative Stress and TP53 Pathway Dysregulation] [Synopsis Renal Cell Carcinomas in Vinylidene Chloride-exposed Male B6C3F1 Mice Are Characterized by Oxidative Stress and TP53 Pathway Dysregulation] Hayes SA, Pandiri AR, Ton TV, Hong HH, Clayton NP, Shockley KR, Peddada SD, Gerrish K, Wyde M, Sills RC, Hoenerhoff MJ. January 2016

Social and Novel Contexts Modify Hippocampal CA2 Representations of Space [Abstract Social and Novel Contexts Modify Hippocampal CA2 Representations of Space] [Synopsis Social and Novel Contexts Modify Hippocampal CA2 Representations of Space] [Story Social and Novel Contexts Modify Hippocampal CA2 Representations of Space] Alexander GM, Farris S, Pirone JR, Zheng C, Colgin LL, Dudek. January 2016

The Crystal Structure of the Ubiquitin-like Domain of Ribosome Assembly Factor Ytm1 and Characterization of Its Interaction with the AAA-ATPase Midasin [Abstract The Crystal Structure of the Ubiquitin-like Domain of Ribosome Assembly Factor Ytm1 and Characterization of Its Interaction with the AAA-ATPase Midasin] [Synopsis The Crystal Structure of the Ubiquitin-like Domain of Ribosome Assembly Factor Ytm1 and Characterization of Its Interaction with the AAA-ATPase Midasin] Romes EM, Sobhany M, Stanley RE. January 2016

Vehicular Traffic-related Polycyclic Aromatic Hydrocarbon Exposure and Breast Cancer Incidence: The Long Island Breast Cancer Study Project (LIBCSP) [Abstract Vehicular Traffic-related Polycyclic Aromatic Hydrocarbon Exposure and Breast Cancer Incidence: The Long Island Breast Cancer Study Project (LIBCSP)] [Synopsis Vehicular Traffic-related Polycyclic Aromatic Hydrocarbon Exposure and Breast Cancer Incidence: The Long Island Breast Cancer Study Project (LIBCSP)] Mordukhovich I, Beyea J, Herring AH, Hatch M, Stellman SD, Teitelbaum SL, Richardson DB, Millikan RC, Engel LS, Shantakumar S, Steck SE, Neugut AI, Rossner P, Santella RM, Gammon MD. January 2016

Gene-expression Profiling of Buccal Epithelium Among Non-smoking Women Exposed to Household Air Pollution From Smoky Coal [Abstract Gene-expression Profiling of Buccal Epithelium Among Non-smoking Women Exposed to Household Air Pollution From Smoky Coal] [Synopsis Gene-expression Profiling of Buccal Epithelium Among Non-smoking Women Exposed to Household Air Pollution From Smoky Coal] Wang TW, Vermeulen RC, Hu W, Liu G, Xiao X, Alekseyev Y, Xu J, Reiss B, Steiling K, Downward GS, Silverman DT, Wei F, Wu G, Li J, Lenburg ME, Rothman N, Spira A, Lan Q. December 2015

Inflammasome Modulation by Chemotherapeutics in Malignant Mesothelioma [Abstract Inflammasome Modulation by Chemotherapeutics in Malignant Mesothelioma] [Synopsis Inflammasome Modulation by Chemotherapeutics in Malignant Mesothelioma] Westbom C, Thompson JK, Leggett A, MacPherson M, Beuschel S, Pass H, Vacek P, Shukla A. December 2015

Integrative Pathway Genomics of Lung Function and Airflow Obstruction [Abstract Integrative Pathway Genomics of Lung Function and Airflow Obstruction] [Synopsis Integrative Pathway Genomics of Lung Function and Airflow Obstruction] Gharib SA, Loth DW, Soler Artigas M, Birkland TP, Wilk JB, Wain LV, Brody JA, Obeidat M, Hancock DB, Tang W, Rawal R, Boezen HM, Imboden M, Huffman JE, Lahousse L, Alves AC, Manichaikul A, Hui J, Morrison AC, Ramasamy A, Smith AV, Gudnason V, Surakka I, Vitart V, Evans DM, Strachan DP, Deary IJ, Hofman A, Glaser S, Wilson JF, North KE, Zhao JH, Heckbert SR, Jarvis DL, Probst-Hensch N, Schulz H, Barr RG, Jarvelin MR, O’Connor GT, Kahonen M, Cassano PA, Hysi PG, Dupuis J, Hayward C, Psaty BM, Hall IP, Parks WC, Tobin MD, London SJ, CHARGE Consortium, SpiroMeta Consortium. December 2015

Oviductal Estrogen Receptor Alpha Signaling Prevents Protease-Mediated Embryo Death [Abstract Oviductal Estrogen Receptor Alpha Signaling Prevents Protease-Mediated Embryo Death] [Synopsis Oviductal Estrogen Receptor Alpha Signaling Prevents Protease-Mediated Embryo Death] Winuthayanon W, Bernhardt ML, Padilla-Banks E, Myers PH, Edin ML, Hewitt SC, Korach KS, Williams CJ. December 2015

Systemic Administration of the Apocarotenoid Bixin Protects Skin Against Solar UV-induced Damage Through Activation of NRF2 [Abstract Systemic Administration of the Apocarotenoid Bixin Protects Skin Against Solar UV-induced Damage Through Activation of NRF2] [Synopsis Systemic Administration of the Apocarotenoid Bixin Protects Skin Against Solar UV-induced Damage Through Activation of NRF2] Tao S, Park SL, de la Vega MR, Zhang DD, Wondrak GT. December 2015

T-Cell Development of Resistance to Apoptosis is Driven by a Metabolic Shift in Carbon Source and Altered Activation of Death Pathways [Abstract T-Cell Development of Resistance to Apoptosis is Driven by a Metabolic Shift in Carbon Source and Altered Activation of Death Pathways] [Synopsis T-Cell Development of Resistance to Apoptosis is Driven by a Metabolic Shift in Carbon Source and Altered Activation of Death Pathways] Bortner CD, Scoltock AB, Cain DW, Cidlowski JA. December 2015

Uterine Glucocorticoid Receptors are Critical for Fertility in Mice Through Control of Embryo Implantation and Decidualization [Abstract Uterine Glucocorticoid Receptors are Critical for Fertility in Mice Through Control of Embryo Implantation and Decidualization] [Synopsis Uterine Glucocorticoid Receptors are Critical for Fertility in Mice Through Control of Embryo Implantation and Decidualization] Whirledge SD, Oakley RH, Myers PH, Lydon JP, DeMayo F, Cidlowski JA. December 2015

Arsenic Promotes NF-kappaB-Mediated Fibroblast Dysfunction and Matrix Remodeling to Impair Muscle Stem Cell Function [Abstract Arsenic Promotes NF-kappaB-Mediated Fibroblast Dysfunction and Matrix Remodeling to Impair Muscle Stem Cell Function] [Synopsis Arsenic Promotes NF-kappaB-Mediated Fibroblast Dysfunction and Matrix Remodeling to Impair Muscle Stem Cell Function] Zhang C, Ferrari R, Beezhold K, Stearns-Reider K, D’Amore A, Haschak M, Stolz D, Robbins PD, Barchowsky A, Ambrosio F. November 2015

Capturing Snapshots of APE1 Processing DNA Damage [Abstract Capturing Snapshots of APE1 Processing DNA Damage] [Synopsis Capturing Snapshots of APE1 Processing DNA Damage] Freudenthal BD, Beard WA, Cuneo MJ, Dyrkheeva NS, Wilson SH. November 2015

Environmental Phenols and Pubertal Development in Girls [Abstract Environmental Phenols and Pubertal Development in Girls] [Synopsis Environmental Phenols and Pubertal Development in Girls] Wolff MS, Teitelbaum SL, McGovern K, Pinney SM, Windham GC, Galvez M, Pajak A, Rybak M, Calafat AM, Kushi LH, Biro FM, Breast Cancer and Environment Research Program. November 2015

Maternal and Fetal Exposure to Parabens in a Multiethnic Urban U.S. Population [Abstract Maternal and Fetal Exposure to Parabens in a Multiethnic Urban U.S. Population] [Synopsis Maternal and Fetal Exposure to Parabens in a Multiethnic Urban U.S. Population] Pycke BF, Geer LA, Dalloul M, Abulafia O, Halden RU. November 2015

Urinary Phthalate Metabolite Concentrations and Reproductive Outcomes Among Women Undergoing In Vitro Fertilization: Results From the EARTH Study [Abstract Urinary Phthalate Metabolite Concentrations and Reproductive Outcomes Among Women Undergoing In Vitro Fertilization: Results From the EARTH Study] [Synopsis Urinary Phthalate Metabolite Concentrations and Reproductive Outcomes Among Women Undergoing In Vitro Fertilization: Results From the EARTH Study] Hauser R, Gaskins AJ, Souter I, Smith KW, Dodge LE, Ehrlich S, Meeker JD, Calafat AM, Williams PL; Earth Study Team. November 2015

Associations of Cognitive Function Scores with Carbon Dioxide, Ventilation, and Volatile Organic Compound Exposures in Office Workers: A Controlled Exposure Study of Green and Conventional Office Environments [Abstract Associations of Cognitive Function Scores with Carbon Dioxide, Ventilation, and Volatile Organic Compound Exposures in Office Workers: A Controlled Exposure Study of Green and Conventional Office Environments] [Synopsis Associations of Cognitive Function Scores with Carbon Dioxide, Ventilation, and Volatile Organic Compound Exposures in Office Workers: A Controlled Exposure Study of Green and Conventional Office Environments] Allen JG, MacNaughton P, Satish U, Santanam S, Vallarino J, Spengler JD. October 2015

CaV3.2 T-type Channels Mediate Ca2+ Entry During Oocyte Maturation and Following Fertilization [Abstract CaV3.2 T-type Channels Mediate Ca2+ Entry During Oocyte Maturation and Following Fertilization] [Synopsis CaV3.2 T-type Channels Mediate Ca2+ Entry During Oocyte Maturation and Following Fertilization] Bernhardt ML, Zhang Y, Erxleben CF, Padilla-Banks E, McDonough CE, Miao YL, Armstrong DL, Williams CJ. October 2015

Developmental Effects of the ToxCast Phase I and II Chemicals in Caenorhabditis elegans and Corresponding Responses in Zebrafish, Rats, and Rabbits [Abstract Developmental Effects of the ToxCast Phase I and II Chemicals in Caenorhabditis elegans and Corresponding Responses in Zebrafish, Rats, and Rabbits] [Synopsis Developmental Effects of the ToxCast Phase I and II Chemicals in Caenorhabditis elegans and Corresponding Responses in Zebrafish, Rats, and Rabbits] Boyd WA, Smith MV, Co CA, Pirone JR, Rice JR, Shockley KR, Freedman JH. October 2015

Interpregnancy Interval and Risk of Autism Spectrum Disorders [Abstract Interpregnancy Interval and Risk of Autism Spectrum Disorders] [Synopsis Interpregnancy Interval and Risk of Autism Spectrum Disorders] Zerbo O, Yoshida C, Gunderson EP, Dorward K, Croen LA. October 2015

Long-Term Air Pollution and Blood Pressure in the Sister Study [Abstract Long-Term Air Pollution and Blood Pressure in the Sister Study] [Synopsis Long-Term Air Pollution and Blood Pressure in the Sister Study] Chan SH, Van Hee VC, Bergen S, Szpiro AA, DeRoo LA, London SJ, Marshall JD, Kaufman JD, Sandler DP. October 2015

Mapping Proteome-Wide Targets of Environmental Chemicals Using Reactivity-Based Chemoproteomic Platforms [Abstract Mapping Proteome-Wide Targets of Environmental Chemicals Using Reactivity-Based Chemoproteomic Platforms] [Synopsis Mapping Proteome-Wide Targets of Environmental Chemicals Using Reactivity-Based Chemoproteomic Platforms] Medina-Cleghorn D, Bateman LA, Ford B, Heslin A, Fisher KJ, Dalvie ED, Nomura DK. October 2015

Population-based in Vitro Hazard and Concentration-response Assessment of Chemicals: The 1000 Genomes High-throughput Screening Study [Abstract Population-based in Vitro Hazard and Concentration-response Assessment of Chemicals: The 1000 Genomes High-throughput Screening Study] [Synopsis Population-based in Vitro Hazard and Concentration-response Assessment of Chemicals: The 1000 Genomes High-throughput Screening Study] Abdo N, Xia M, Brown CC, Kosyk O, Huang R, Sakamuru S, Zhou YH, Jack JR, Gallins P, Xia K, Li Y, Chiu WA, Motsinger-Reif AA, Austin CP, Tice RR, Rusyn I, Wright FA. October 2015

Recombinational Repair of Radiation-Induced Double-Strand Breaks Occurs in the Absence of Extensive Resection [Abstract Recombinational Repair of Radiation-Induced Double-Strand Breaks Occurs in the Absence of Extensive Resection] [Synopsis Recombinational Repair of Radiation-Induced Double-Strand Breaks Occurs in the Absence of Extensive Resection] Westmoreland JW, Resnick MA. October 2015

"One-Shot" Analysis of Polybrominated Diphenyl Ethers and Their Hydroxylated and Methoxylated Analogs in Human Breast Milk and Serum Using Gas Chromatography-Tandem Mass Spectrometry [Abstract "One-Shot" Analysis of Polybrominated Diphenyl Ethers and Their Hydroxylated and Methoxylated Analogs in Human Breast Milk and Serum Using Gas Chromatography-Tandem Mass Spectrometry] [Synopsis "One-Shot" Analysis of Polybrominated Diphenyl Ethers and Their Hydroxylated and Methoxylated Analogs in Human Breast Milk and Serum Using Gas Chromatography-Tandem Mass Spectrometry] Butryn DM, Gross MS, Chi LH, Schecter A, Olson JR, Aga DS. September 2015

An APOBEC3A Hypermutation Signature Is Distinguishable From the Signature of Background Mutagenesis By APOBEC3B in Human Cancers [Abstract An APOBEC3A Hypermutation Signature Is Distinguishable From the Signature of Background Mutagenesis By APOBEC3B in Human Cancers] [Synopsis An APOBEC3A Hypermutation Signature Is Distinguishable From the Signature of Background Mutagenesis By APOBEC3B in Human Cancers] [Story An APOBEC3A Hypermutation Signature Is Distinguishable From the Signature of Background Mutagenesis By APOBEC3B in Human Cancers] Chan K, Roberts SA, Klimczak LJ, Sterling JF, Saini N, Malc EP, Kim J, Kwiatkowski DJ, Fargo DC, Mieczkowski PA, Getz G, Gordenin DA. September 2015

MiRNA-mediated Regulation of the SWI/SNF Chromatin Remodeling Complex Controls Pluripotency and Endodermal Differentiation in Human ESCs [Abstract MiRNA-mediated Regulation of the SWI/SNF Chromatin Remodeling Complex Controls Pluripotency and Endodermal Differentiation in Human ESCs] [Synopsis MiRNA-mediated Regulation of the SWI/SNF Chromatin Remodeling Complex Controls Pluripotency and Endodermal Differentiation in Human ESCs] Wade SL, Langer LF, Ward JM, Archer TK. September 2015

Multigenerational Epigenetic Inheritance in Humans: DNA Methylation Changes Associated with Maternal Exposure to Lead Can Be Transmitted to the Grandchildren [Abstract Multigenerational Epigenetic Inheritance in Humans: DNA Methylation Changes Associated with Maternal Exposure to Lead Can Be Transmitted to the Grandchildren] [Synopsis Multigenerational Epigenetic Inheritance in Humans: DNA Methylation Changes Associated with Maternal Exposure to Lead Can Be Transmitted to the Grandchildren] Sen A, Heredia N, Senut MC, Land S, Hollocher K, Lu X, Dereski MO, Ruden DM. September 2015

POLG2 Disease Variants: Analyses Reveal a Dominant Negative Heterodimer, Altered Mitochondrial Localization and Impaired Respiratory Capacity [Abstract POLG2 Disease Variants: Analyses Reveal a Dominant Negative Heterodimer, Altered Mitochondrial Localization and Impaired Respiratory Capacity] [Synopsis POLG2 Disease Variants: Analyses Reveal a Dominant Negative Heterodimer, Altered Mitochondrial Localization and Impaired Respiratory Capacity] Young MJ, Humble MM, DeBalsi KL, Sun KY, Copeland WC. September 2015

Prenatal Exposure to Polybrominated Diphenyl Ethers and Child Attention Problems at 3-7 Years [Abstract Prenatal Exposure to Polybrominated Diphenyl Ethers and Child Attention Problems at 3-7 Years] [Synopsis Prenatal Exposure to Polybrominated Diphenyl Ethers and Child Attention Problems at 3-7 Years] Cowell WJ, Lederman SA, Sjodin A, Jones R, Wang S, Perera FP, Wang R, Rauh VA, Herbstman JB. September 2015

Requirement for Transient Metal Ions Revealed Through Computational Analysis for DNA Polymerase Going in Reverse [Abstract Requirement for Transient Metal Ions Revealed Through Computational Analysis for DNA Polymerase Going in Reverse] [Synopsis Requirement for Transient Metal Ions Revealed Through Computational Analysis for DNA Polymerase Going in Reverse] Perera L, Freudenthal BD, Beard WA, Shock DD, Pedersen LG, Wilson SH. September 2015

Statin-Activated Nuclear Receptor PXR Promotes SGK2 Dephosphorylation By Scaffolding PP2C to Induce Hepatic Gluconeogenesis [Abstract Statin-Activated Nuclear Receptor PXR Promotes SGK2 Dephosphorylation By Scaffolding PP2C to Induce Hepatic Gluconeogenesis] [Synopsis Statin-Activated Nuclear Receptor PXR Promotes SGK2 Dephosphorylation By Scaffolding PP2C to Induce Hepatic Gluconeogenesis] Gotoh S, Negishi M. September 2015

Targeting the Isoprenoid Pathway to Abrogate Progression of Pulmonary Fibrosis [Abstract Targeting the Isoprenoid Pathway to Abrogate Progression of Pulmonary Fibrosis] [Synopsis Targeting the Isoprenoid Pathway to Abrogate Progression of Pulmonary Fibrosis] Osborn-Heaford HL, Murthy S, Gu L, Larson-Casey JL, Ryan AJ, Shi L, Glogauer M, Neighbors JD, Hohl R, Brent Carter A. September 2015

Unconventional Natural Gas Development and Birth Outcomes in Pennsylvania, USA [Abstract Unconventional Natural Gas Development and Birth Outcomes in Pennsylvania, USA] [Synopsis Unconventional Natural Gas Development and Birth Outcomes in Pennsylvania, USA] Casey JA, Savitz DA, Rasmussen SG, Ogburn EL, Pollak J, Mercer DG, Schwartz BS. September 2015

Use of Alternative Assays to Identify and Prioritize Organophosphorus Flame Retardants for Potential Developmental and Neurotoxicity [Abstract Use of Alternative Assays to Identify and Prioritize Organophosphorus Flame Retardants for Potential Developmental and Neurotoxicity] [Synopsis Use of Alternative Assays to Identify and Prioritize Organophosphorus Flame Retardants for Potential Developmental and Neurotoxicity] Behl M, Hsieh JH, Shafer TJ, Mundy WR, Rice JR, Boyd WA, Freedman JH, Hunter ES 3rd, Jarema KA, Padilla S, Tice RR. September 2015

An Autism-Linked Mutation Disables Phosphorylation Control of UBE3A [Abstract An Autism-Linked Mutation Disables Phosphorylation Control of UBE3A] [Synopsis An Autism-Linked Mutation Disables Phosphorylation Control of UBE3A] Yi JJ, Berrios J, Newbern JM, Snider WD, Philpot BD, Hahn KM, Zylka MJ. August 2015

Association of Exposure to Di-2-Ethylhexyphthalate Replacements With Increased Blood Pressure in Children and Adolescents [Abstract Association of Exposure to Di-2-Ethylhexyphthalate Replacements With Increased Blood Pressure in Children and Adolescents] [Synopsis Association of Exposure to Di-2-Ethylhexyphthalate Replacements With Increased Blood Pressure in Children and Adolescents] Trasande L, Attina TM. August 2015

Associations Between Selected Xenobiotics and Antinuclear Antibodies in the National Health and Nutrition Examination Survey, 1999-2004 [Abstract Associations Between Selected Xenobiotics and Antinuclear Antibodies in the National Health and Nutrition Examination Survey, 1999-2004] [Synopsis Associations Between Selected Xenobiotics and Antinuclear Antibodies in the National Health and Nutrition Examination Survey, 1999-2004] Dinse GE, Jusko TA, Whitt IZ, Co CA, Parks CG, Satoh M, Chan EK, Rose KM, Walker NJ, Birnbaum LS, Zeldin DC, Weinberg CR, Miller FW. August 2015

Base Triplet Stepping by the Rad51/RecA Family of Recombinases [Abstract Base Triplet Stepping by the Rad51/RecA Family of Recombinases] [Synopsis Base Triplet Stepping by the Rad51/RecA Family of Recombinases] Lee JY, Terakawa T, Qi Z, Steinfeld JB, Redding S, Kwon Y, Gaines WA, Zhao W, Sung P, Greene EC. August 2015

Creative Template-Dependent Synthesis by Human Polymerase Mu [Abstract Creative Template-Dependent Synthesis by Human Polymerase Mu] [Synopsis Creative Template-Dependent Synthesis by Human Polymerase Mu] Moon AF, Gosavi RA, Kunkel TA, Pedersen LC, Bebenek K. August 2015

Current and Projected Heat-Related Morbidity and Mortality in Rhode Island [Abstract Current and Projected Heat-Related Morbidity and Mortality in Rhode Island] [Synopsis Current and Projected Heat-Related Morbidity and Mortality in Rhode Island] Kingsley SL, Eliot MN, Gold J, Vanderslice RR, Wellenius GA. August 2015

Effects of In Utero Exposure To Arsenic During the Second Half of Gestation on Reproductive End Points and Metabolic Parameters in Female CD-1 Mice [Abstract Effects of In Utero Exposure To Arsenic During the Second Half of Gestation on Reproductive End Points and Metabolic Parameters in Female CD-1 Mice] [Synopsis Effects of In Utero Exposure To Arsenic During the Second Half of Gestation on Reproductive End Points and Metabolic Parameters in Female CD-1 Mice] [Story Effects of In Utero Exposure To Arsenic During the Second Half of Gestation on Reproductive End Points and Metabolic Parameters in Female CD-1 Mice] Rodriguez KF, Ungewitter EK, Crespo-Mejias Y, Liu C, Nicol B, Kissling GE, Yao HH. August 2015

Endotoxin Exposure: Predictors and Prevalence of Associated Asthma Outcomes in the U.S. [Abstract Endotoxin Exposure: Predictors and Prevalence of Associated Asthma Outcomes in the U.S.] [Synopsis Endotoxin Exposure: Predictors and Prevalence of Associated Asthma Outcomes in the U.S.] Thorne PS, Mendy A, Metwali N, Salo P, Co C, Jaramillo R, Rose KM, Zeldin DC. August 2015

Genomic Profiling Reveals Unique Molecular Alterations in Hepatoblastomas and Adjacent Hepatocellular Carcinomas in B6C3F1 Mice [Abstract Genomic Profiling Reveals Unique Molecular Alterations in Hepatoblastomas and Adjacent Hepatocellular Carcinomas in B6C3F1 Mice] [Synopsis Genomic Profiling Reveals Unique Molecular Alterations in Hepatoblastomas and Adjacent Hepatocellular Carcinomas in B6C3F1 Mice] Bhusari S, Pandiri AR, Nagai H, Wang Y, Foley J, Hong HL, Ton TV, DeVito M, Shockley KR, Peddada SD, Gerrish KE, Malarkey DE, Hooth MJ, Sills RC, Hoenerhoff MJ. August 2015

Kras, Egfr, and Tp53 Mutations in B6C3F1/N Mouse and F344/NTac Rat Alveolar/Bronchiolar Carcinomas Resulting from Chronic Inhalation Exposure to Cobalt Metal [Abstract Kras, Egfr, and Tp53 Mutations in B6C3F1/N Mouse and F344/NTac Rat Alveolar/Bronchiolar Carcinomas Resulting from Chronic Inhalation Exposure to Cobalt Metal] [Synopsis Kras, Egfr, and Tp53 Mutations in B6C3F1/N Mouse and F344/NTac Rat Alveolar/Bronchiolar Carcinomas Resulting from Chronic Inhalation Exposure to Cobalt Metal] Hong HL, Hoenerhoff MJ, Ton TV, Herbert RA, Kissling GE, Hooth MJ, Behl M, Witt KL, Smith-Roe SL, Sill RC, Pandiri AR. August 2015

Nuclear Localization of the DNA Repair Scaffold XRCC1: Uncovering the Functional Role of a Bipartite NLS [Abstract Nuclear Localization of the DNA Repair Scaffold XRCC1: Uncovering the Functional Role of a Bipartite NLS] [Synopsis Nuclear Localization of the DNA Repair Scaffold XRCC1: Uncovering the Functional Role of a Bipartite NLS] Kirby TW, Gassman NR, Smith CE, Pedersen LC, Gabel SA, Sobhany M, Wilson SH, London RE. August 2015

Regulator of G-Protein Signaling 2 (RGS2) Suppresses Premature Calcium Release in Mouse Eggs [Abstract Regulator of G-Protein Signaling 2 (RGS2) Suppresses Premature Calcium Release in Mouse Eggs] [Synopsis Regulator of G-Protein Signaling 2 (RGS2) Suppresses Premature Calcium Release in Mouse Eggs] [Story Regulator of G-Protein Signaling 2 (RGS2) Suppresses Premature Calcium Release in Mouse Eggs] Bernhardt ML, Lowther KM, Padilla-Banks E, McDonough CE, Lee KN, Evsikov AV, Uliasz TF, Chidiac P, Williams CJ, Mehlmann LM. August 2015

Season and Preterm Birth in Norway: A Cautionary Tale [Abstract Season and Preterm Birth in Norway: A Cautionary Tale] [Synopsis Season and Preterm Birth in Norway: A Cautionary Tale] Weinberg CR, Shi M, DeRoo LA, Basso O, Skjaerven R. August 2015

Cell-Based High-Throughput Screening for Aromatase Inhibitors in the Tox21 10K Library [Abstract Cell-Based High-Throughput Screening for Aromatase Inhibitors in the Tox21 10K Library] [Synopsis Cell-Based High-Throughput Screening for Aromatase Inhibitors in the Tox21 10K Library] Chen S, Hsieh JH, Huang R, Sakamuru S, Hsin LY, Xia M, Shockley KR, Auerbach S, Kanaya N, Lu H, Svoboda D, Witt KL, Merrick BA, Teng CT, Tice RR. July 2015

Chronic Inorganic Arsenic Exposure In Vitro Induces a Cancer Cell Phenotype in Human Peripheral Lung Epithelial Cells [Abstract Chronic Inorganic Arsenic Exposure In Vitro Induces a Cancer Cell Phenotype in Human Peripheral Lung Epithelial Cells] [Synopsis Chronic Inorganic Arsenic Exposure In Vitro Induces a Cancer Cell Phenotype in Human Peripheral Lung Epithelial Cells] Person RJ, Olive Ngalame NN, Makia NL, Bell MW, Waalkes MP, Tokar EJ. July 2015

Exposure to Deepwater Horizon Crude Oil Burnoff Particulate Matter Induces Pulmonary Inflammation and Alters Adaptive Immune Response [Abstract Exposure to Deepwater Horizon Crude Oil Burnoff Particulate Matter Induces Pulmonary Inflammation and Alters Adaptive Immune Response] [Synopsis Exposure to Deepwater Horizon Crude Oil Burnoff Particulate Matter Induces Pulmonary Inflammation and Alters Adaptive Immune Response] Jaligama S, Chen Z, Saravia J, Yadav N, Lomnicki SM, Dugas TR, Cormier SA. July 2015

Human Body Epigenome Maps Reveal Noncanonical DNA Methylation Variation [Abstract Human Body Epigenome Maps Reveal Noncanonical DNA Methylation Variation] [Synopsis Human Body Epigenome Maps Reveal Noncanonical DNA Methylation Variation] Schultz MD, He Y, Whitaker JW, Hariharan M, Mukamel EA, Leung D, Rajagopal N, Nery JR, Urich MA, Chen H, Lin S, Lin Y, Jung I, Schmitt AD, Selvaraj S, Ren B, Sejnowski TJ, Wang W, Ecker JR. July 2015

Lack of Cross-reactivity Between GST Allergens Could Lead to New Diagnostic Tools [Abstract Lack of Cross-reactivity Between GST Allergens Could Lead to New Diagnostic Tools] [Synopsis Lack of Cross-reactivity Between GST Allergens Could Lead to New Diagnostic Tools] Mueller GA, Pedersen LC, Glesner J, Edwards LL, Zakzuk J, London RE, Arruda LK, Chapman MD, Caraballo L, Pomes A. July 2015

Multiplexed Paper Analytical Device for Quantification of Metals Using Distance-Based Detection [Abstract Multiplexed Paper Analytical Device for Quantification of Metals Using Distance-Based Detection] [Synopsis Multiplexed Paper Analytical Device for Quantification of Metals Using Distance-Based Detection] Cate DM, Noblitt SD, Volckens J, Henry CS. July 2015

Proteomic Analysis of ABCA1-Null Macrophages Reveals a Role for Stomatin-Like Protein-2 in Raft Composition and Toll-Like Receptor Signaling [Abstract Proteomic Analysis of ABCA1-Null Macrophages Reveals a Role for Stomatin-Like Protein-2 in Raft Composition and Toll-Like Receptor Signaling] [Synopsis Proteomic Analysis of ABCA1-Null Macrophages Reveals a Role for Stomatin-Like Protein-2 in Raft Composition and Toll-Like Receptor Signaling] Chowdhury SM, Zhu X, Aloor JJ, Azzam KM, Gabor KA, Ge W, Addo KA, Tomer KB, Parks JS, Fessler MB. July 2015

Role of the Store-Operated Calcium Entry Protein, STIM1, in Neutrophil Chemotaxis and Infiltration Into a Murine Model of Psoriasis-Inflamed Skin [Abstract Role of the Store-Operated Calcium Entry Protein, STIM1, in Neutrophil Chemotaxis and Infiltration Into a Murine Model of Psoriasis-Inflamed Skin] [Synopsis Role of the Store-Operated Calcium Entry Protein, STIM1, in Neutrophil Chemotaxis and Infiltration Into a Murine Model of Psoriasis-Inflamed Skin] Steinckwich N, Myers P, Janardhan KS, Flagler ND, King D, Petranka JG, Putney JW. July 2015

Transactivation Function-2 of Estrogen Receptor Alpha Contains Transactivation Function-1-Regulating Element [Abstract Transactivation Function-2 of Estrogen Receptor Alpha Contains Transactivation Function-1-Regulating Element] [Synopsis Transactivation Function-2 of Estrogen Receptor Alpha Contains Transactivation Function-1-Regulating Element] Arao Y, Coons LA, Zuercher WJ, Korach KS. July 2015

Unconventional Gas and Oil Drilling is Associated With Increased Hospital Utilization Rates [Abstract Unconventional Gas and Oil Drilling is Associated With Increased Hospital Utilization Rates] [Synopsis Unconventional Gas and Oil Drilling is Associated With Increased Hospital Utilization Rates] [Story Unconventional Gas and Oil Drilling is Associated With Increased Hospital Utilization Rates] Jemielita T, Gerton GL, Neidell M, Chillrud S, Yan B, Stute M, Howarth M, Saberi P, Fausti N, Penning TM, Roy J, Propert KJ, Panettieri RA Jr. July 2015

Urinary Concentrations of Phthalate Metabolites and Bisphenol A and Associations with Follicular-Phase Length, Luteal-Phase Length, Fecundability, and Early Pregnancy Loss [Abstract Urinary Concentrations of Phthalate Metabolites and Bisphenol A and Associations with Follicular-Phase Length, Luteal-Phase Length, Fecundability, and Early Pregnancy Loss] [Synopsis Urinary Concentrations of Phthalate Metabolites and Bisphenol A and Associations with Follicular-Phase Length, Luteal-Phase Length, Fecundability, and Early Pregnancy Loss] Jukic AM, Calafat AM, McConnaughey DR, Longnecker MP, Hoppin JA, Weinberg CR, Wilcox AJ, Baird DD. July 2015

Asymmetric Conformational Maturation of HIV-1 Reverse Transcriptase [Abstract Asymmetric Conformational Maturation of HIV-1 Reverse Transcriptase] [Synopsis Asymmetric Conformational Maturation of HIV-1 Reverse Transcriptase] Zheng X, Perera L, Mueller GA, DeRose EF, London RE. June 2015

Bidirectional Transcription Arises from Two Distinct Hubs of Transcription Factor Binding and Active Chromatin [Abstract Bidirectional Transcription Arises from Two Distinct Hubs of Transcription Factor Binding and Active Chromatin] [Synopsis Bidirectional Transcription Arises from Two Distinct Hubs of Transcription Factor Binding and Active Chromatin] Scruggs BS, Gilchrist DA, Nechaev S, Muse GW, Burkholder A, Fargo DC, Adelman K. June 2015

DDT Exposure In Utero and Breast Cancer [Abstract DDT Exposure In Utero and Breast Cancer] [Synopsis DDT Exposure In Utero and Breast Cancer] Cohn BA, La Merrill M, Krigbaum NY, Yeh G, Park JS, Zimmermann L, Cirillo PM. June 2015

Development of Phenotypic and Transcriptional Biomarkers to Evaluate Relative Activity of Potentially Estrogenic Chemicals in Ovariectomized Mice [Abstract Development of Phenotypic and Transcriptional Biomarkers to Evaluate Relative Activity of Potentially Estrogenic Chemicals in Ovariectomized Mice] [Synopsis Development of Phenotypic and Transcriptional Biomarkers to Evaluate Relative Activity of Potentially Estrogenic Chemicals in Ovariectomized Mice] Hewitt SC, Winuthayanon W, Pockette B, Kerns RT, Foley JF, Flagler N, Ney E, Suksamrarn A, Piyachaturawat P, Bushel PR, Korach KS. June 2015

Disruption of Parenting Behaviors in California Mice, a Monogamous Rodent Species, by Endocrine Disrupting Chemicals [Abstract Disruption of Parenting Behaviors in California Mice, a Monogamous Rodent Species, by Endocrine Disrupting Chemicals] [Synopsis Disruption of Parenting Behaviors in California Mice, a Monogamous Rodent Species, by Endocrine Disrupting Chemicals] Johnson SA, Javurek AB, Painter MS, Peritore MP, Ellersieck MR, Roberts RM, Rosenfeld CS. June 2015

Mechanism-Based Classification of PAH Mixtures to Predict Carcinogenic Potential [Abstract Mechanism-Based Classification of PAH Mixtures to Predict Carcinogenic Potential] [Synopsis Mechanism-Based Classification of PAH Mixtures to Predict Carcinogenic Potential] Tilton SC, Siddens LK, Krueger SK, Larkin AJ, Lohr CV, Williams DE, Baird WM, Waters KM. June 2015

Performance of the BG1Luc ER TA Method in a qHTS Format [Abstract Performance of the BG1Luc ER TA Method in a qHTS Format] [Synopsis Performance of the BG1Luc ER TA Method in a qHTS Format] Ceger P, Allen D, Huang R, Xia M, Casey W. June 2015

Blood Pressure Changes in Relation to Arsenic Exposure in a U.S. Pregnancy Cohort [Abstract Blood Pressure Changes in Relation to Arsenic Exposure in a U.S. Pregnancy Cohort] [Synopsis Blood Pressure Changes in Relation to Arsenic Exposure in a U.S. Pregnancy Cohort] Farzan SF, Chen Y, Wu F, Jiang J, Liu M, Baker E, Korrick SA, Karagas MR. May 2015

Essential Role of Orai1 Store-Operated Calcium Channels in Lactation [Abstract Essential Role of Orai1 Store-Operated Calcium Channels in Lactation] [Synopsis Essential Role of Orai1 Store-Operated Calcium Channels in Lactation] Davis FM, Janoshazi A, Janardhan KS, Steinckwich N, D’Agostin DM, Petranka JG, Desai PN, Roberts-Thomson SJ, Bird GS, Tucker DK, Fenton SE, Feske S, Monteith GR, Putney JW Jr. May 2015

Heart Rate Variability and the Risk of Parkinson Disease: The Atherosclerosis Risk in Communities Study [Abstract Heart Rate Variability and the Risk of Parkinson Disease: The Atherosclerosis Risk in Communities Study] [Synopsis Heart Rate Variability and the Risk of Parkinson Disease: The Atherosclerosis Risk in Communities Study] Alonso A, Huang X, Mosley TH, Heiss G, Chen H. May 2015

Human Erythrocyte PIG-A Assay: An Easily Monitored Index of Gene Mutation Requiring Low Volume Blood Samples [Abstract Human Erythrocyte PIG-A Assay: An Easily Monitored Index of Gene Mutation Requiring Low Volume Blood Samples] [Synopsis Human Erythrocyte PIG-A Assay: An Easily Monitored Index of Gene Mutation Requiring Low Volume Blood Samples] Dertinger SD, Avlasevich SL, Bemis JC, Chen Y, MacGregor JT. May 2015

Is Bad Luck the Main Cause of Cancer? [Abstract Is Bad Luck the Main Cause of Cancer?] [Synopsis Is Bad Luck the Main Cause of Cancer?] [Story Is Bad Luck the Main Cause of Cancer?] Weinberg CR, Zaykin D. May 2015

Nrf2-Dependent Suppression of Azoxymethane/Dextran Sulfate Sodium-Induced Colon Carcinogenesis by the Cinnamon-Derived Dietary Factor Cinnamaldehyde [Abstract Nrf2-Dependent Suppression of Azoxymethane/Dextran Sulfate Sodium-Induced Colon Carcinogenesis by the Cinnamon-Derived Dietary Factor Cinnamaldehyde] [Synopsis Nrf2-Dependent Suppression of Azoxymethane/Dextran Sulfate Sodium-Induced Colon Carcinogenesis by the Cinnamon-Derived Dietary Factor Cinnamaldehyde] Long M, Tao S, Rojo de la Vega M, Jiang T, Web Q, Park SL, Zhang DD, Wondrak GT. May 2015

Post-treatment With an Ultra-low Dose of NADPH Oxidase Inhibitor Diphenyleneiodonium Attenuates Disease Progression in Multiple Parkinson’s Disease Models [Abstract Post-treatment With an Ultra-low Dose of NADPH Oxidase Inhibitor Diphenyleneiodonium Attenuates Disease Progression in Multiple Parkinson’s Disease Models] [Synopsis Post-treatment With an Ultra-low Dose of NADPH Oxidase Inhibitor Diphenyleneiodonium Attenuates Disease Progression in Multiple Parkinson’s Disease Models] Wang Q, Qian L, Chen SH, Chu CH, Wilson B, Oyarzabal E, Ali S, Robinson B, Rao D, Hong JS. May 2015

Potential Sex Differences in Nonmotor Symptoms in Early Drug-Naive Parkinson Disease [Abstract Potential Sex Differences in Nonmotor Symptoms in Early Drug-Naive Parkinson Disease] [Synopsis Potential Sex Differences in Nonmotor Symptoms in Early Drug-Naive Parkinson Disease] Liu R, Umbach DM, Peddada SD, Xu Z, Troster AI, Huang X, Chen H. May 2015

TLR4 Genotype and Environmental LPS Mediate RSV Bronchiolitis Through Th2 Polarization [Abstract TLR4 Genotype and Environmental LPS Mediate RSV Bronchiolitis Through Th2 Polarization] [Synopsis TLR4 Genotype and Environmental LPS Mediate RSV Bronchiolitis Through Th2 Polarization] Caballero MT, Serra ME, Acosta PL, Marzec J, Gibbons L, Salim M, Rodriguez A, Reynaldi A, Garcia A, Bado D, Buchholz UJ, Hijano DR, Coviello S, Newcomb D, Bellabarba M, Ferolla FM, Libster R, Berenstein A, Siniawaski S, Blumetti V, Echavarria M, Pinto L, Lawrence A, Ossorio MF, Grosman A, Mateu CG, Bayle C, Dericco A, Pellegrini M, Igarza I, Repetto HA, Grimaldi LA, Gudapati P, Polack NR, Althabe F, Shi M, Ferrero F, Bergel E, Stein RT, Peebles RS, Boothby M, Kleeberger SR, Polack FP. May 2015

A Data Analysis Pipeline Accounting for Artifacts in Tox21 Quantitative High-Throughput Screening Assays [Abstract A Data Analysis Pipeline Accounting for Artifacts in Tox21 Quantitative High-Throughput Screening Assays] [Synopsis A Data Analysis Pipeline Accounting for Artifacts in Tox21 Quantitative High-Throughput Screening Assays] Hsieh JH, Sedykh A, Huang R, Xia M, Tice RR. April 2015

Alpha-Synuclein, a Chemoattractant, Directs Microglial Migration Via H202-Dependent Lyn Phosphorylation [Abstract Alpha-Synuclein, a Chemoattractant, Directs Microglial Migration Via H202-Dependent Lyn Phosphorylation] [Synopsis Alpha-Synuclein, a Chemoattractant, Directs Microglial Migration Via H202-Dependent Lyn Phosphorylation] Wang S, Chu CH, Stewart T, Ginghina C, Wang Y, Nie H, Guo M, Wilson B, Hong JS, Zhang J. April 2015

Biomarkers of Oxidative Stress Study VI. Endogenous Plasma Antioxidants Fail As Useful Biomarkers of Endotoxin-Induced Oxidative Stress [Abstract Biomarkers of Oxidative Stress Study VI. Endogenous Plasma Antioxidants Fail As Useful Biomarkers of Endotoxin-Induced Oxidative Stress] [Synopsis Biomarkers of Oxidative Stress Study VI. Endogenous Plasma Antioxidants Fail As Useful Biomarkers of Endotoxin-Induced Oxidative Stress] Kadiiska MB, Peddada S, Herbert RA, Basu S, Hensley K, Jones DP, Hatch GE, Mason RP. April 2015

Childhood Acute Lymphoblastic Leukemia and Indicators of Early Immune Stimulation: A Childhood Leukemia International Consortium Study [Abstract Childhood Acute Lymphoblastic Leukemia and Indicators of Early Immune Stimulation: A Childhood Leukemia International Consortium Study] [Synopsis Childhood Acute Lymphoblastic Leukemia and Indicators of Early Immune Stimulation: A Childhood Leukemia International Consortium Study] Rudant J, Lightfoot T, Urayama KY, Petridou E, Dockerty JD, Magnani C, Milne E, Spector LG, Ashton LJ, Dessypris N, Kang AY, Miller M, Rondelli R, Simpson J, Stiakaki E, Orsi L, Roman E, Metayer C, Infante-Rivard C, Clavel J. April 2015

Differences in Birth Weight Associated With the 2008 Beijing Olympic Air Pollution Reduction: Results From a Natural Experiment [Abstract Differences in Birth Weight Associated With the 2008 Beijing Olympic Air Pollution Reduction: Results From a Natural Experiment] [Synopsis Differences in Birth Weight Associated With the 2008 Beijing Olympic Air Pollution Reduction: Results From a Natural Experiment] Rich DQ, Liu K, Zhang J, Thurston SW, Stevens TP, Pan Y, Kane C, Weinberger B, Ohman-Strickland P, Woodruff TJ, Duan X, Assibey-Mensah V, Zhang J. April 2015

Differences in Genome-Wide Repeat Sequence Instability Conferred By Proofreading and Mismatch Repair Defects [Abstract Differences in Genome-Wide Repeat Sequence Instability Conferred By Proofreading and Mismatch Repair Defects] [Synopsis Differences in Genome-Wide Repeat Sequence Instability Conferred By Proofreading and Mismatch Repair Defects] Lujan SA, Clark AB, Kunkel TA. April 2015

Evidence That Processing of Ribonucleotides in DNA by Topoisomerase 1 is Leading-strand Specific [Abstract Evidence That Processing of Ribonucleotides in DNA by Topoisomerase 1 is Leading-strand Specific] [Synopsis Evidence That Processing of Ribonucleotides in DNA by Topoisomerase 1 is Leading-strand Specific] Williams JS, Clausen AR, Lujan SA, Marjavaara L, Clark AB, Burgers PM, Chabes A, Kunkel TA. April 2015

In Utero and Early Childhood Exposure To Arsenic Decreases Lung Function in Children [Abstract In Utero and Early Childhood Exposure To Arsenic Decreases Lung Function in Children] [Synopsis In Utero and Early Childhood Exposure To Arsenic Decreases Lung Function in Children] Recio-Vega R, Gonzalez-Cortes T, Olivas-Calderon E, Lantz RC, Gandolfi AJ, Alba CG. April 2015

Lineage Specification of Ovarian Theca Cells Requires Multicellular Interactions Via Oocyte and Granulosa Cells [Abstract Lineage Specification of Ovarian Theca Cells Requires Multicellular Interactions Via Oocyte and Granulosa Cells] [Synopsis Lineage Specification of Ovarian Theca Cells Requires Multicellular Interactions Via Oocyte and Granulosa Cells] [Story Lineage Specification of Ovarian Theca Cells Requires Multicellular Interactions Via Oocyte and Granulosa Cells] Liu C, Peng J, Matzuk MM, Yao HH. April 2015

Novel Three Dimensional Human Endocervix Cultures Respond to 28-Day Hormone Treatment [Abstract Novel Three Dimensional Human Endocervix Cultures Respond to 28-Day Hormone Treatment] [Synopsis Novel Three Dimensional Human Endocervix Cultures Respond to 28-Day Hormone Treatment] Arslan SY, Yu Y, Burdette JE, Pavone ME, Hope TJ, Woodruff TK, Kim JJ. April 2015

Pausing of RNA Polymerase II Regulates Mammalian Developmental Potential through Control of Signaling Networks [Abstract Pausing of RNA Polymerase II Regulates Mammalian Developmental Potential through Control of Signaling Networks] [Synopsis Pausing of RNA Polymerase II Regulates Mammalian Developmental Potential through Control of Signaling Networks] [Story Pausing of RNA Polymerase II Regulates Mammalian Developmental Potential through Control of Signaling Networks] Williams LH, Fromm G, Gokey NG, Henriques T, Muse GW, Burkholder A, Fargo DC, Hu G, Adelman K. April 2015

Th17 Cells Transdifferentiate Into Regulatory T Cells During Resolution of Inflammation [Abstract Th17 Cells Transdifferentiate Into Regulatory T Cells During Resolution of Inflammation] [Synopsis Th17 Cells Transdifferentiate Into Regulatory T Cells During Resolution of Inflammation] Gagliani N, Vesely MC, Iseppon A, Brockmann L, Xu H, Palm NW, de Zoete MR, Licona-Limon P, Paiva RS, Ching T, Weaver C, Zi X, Pan X, Fan R, Garmire LX, Cotton MJ, Drier Y, Bernstein B, Geginat J, Stockinger B, Esplugues E, Huber S, Flavell RA. April 2015

The Effects of In Utero Bisphenol A Exposure on Reproductive Capacity in Several Generations of Mice [Abstract The Effects of In Utero Bisphenol A Exposure on Reproductive Capacity in Several Generations of Mice] [Synopsis The Effects of In Utero Bisphenol A Exposure on Reproductive Capacity in Several Generations of Mice] Ziv-Gal A, Wang W, Zhou C, Flaws JA. April 2015

Association of Improved Air Quality with Lung Development in Children [Abstract Association of Improved Air Quality with Lung Development in Children] [Synopsis Association of Improved Air Quality with Lung Development in Children] Gauderman WJ, Urman R, Avol E, Berhane K, McConnell R, Rappaport E, Chang R, Lurmann F, Gilliland F. March 2015

Bisphenol A Alters Autonomic Tone and Extracellular Matrix Structure and Induces Sex-Specific Effects on Cardiovascular Function in Male and Female CD-1 Mice [Abstract Bisphenol A Alters Autonomic Tone and Extracellular Matrix Structure and Induces Sex-Specific Effects on Cardiovascular Function in Male and Female CD-1 Mice] [Synopsis Bisphenol A Alters Autonomic Tone and Extracellular Matrix Structure and Induces Sex-Specific Effects on Cardiovascular Function in Male and Female CD-1 Mice] Belcher SM, Gear RB, Kendig EL. March 2015

Early-life Lead Exposure Recapitulates the Selective Loss of Parvalbumin-positive GABAergic Interneurons and Subcortical Dopamine System Hyperactivity Present in Schizophrenia [Abstract Early-life Lead Exposure Recapitulates the Selective Loss of Parvalbumin-positive GABAergic Interneurons and Subcortical Dopamine System Hyperactivity Present in Schizophrenia] [Synopsis Early-life Lead Exposure Recapitulates the Selective Loss of Parvalbumin-positive GABAergic Interneurons and Subcortical Dopamine System Hyperactivity Present in Schizophrenia] Stansfield KH, Ruby KN, Soares BD, McGlothan JL, Liu X, Guilarte TR. March 2015

Effects of Prenatal Exposure to Air Pollutants (Polycyclic Aromatic Hydrocarbons) on the Development of Brain White Matter, Cognition, and Behavior in Later Childhood [Abstract Effects of Prenatal Exposure to Air Pollutants (Polycyclic Aromatic Hydrocarbons) on the Development of Brain White Matter, Cognition, and Behavior in Later Childhood] [Synopsis Effects of Prenatal Exposure to Air Pollutants (Polycyclic Aromatic Hydrocarbons) on the Development of Brain White Matter, Cognition, and Behavior in Later Childhood] [Story Effects of Prenatal Exposure to Air Pollutants (Polycyclic Aromatic Hydrocarbons) on the Development of Brain White Matter, Cognition, and Behavior in Later Childhood] Peterson BS, Rauh VA, Bansal R, Hao X, Toth Z, Nati G, Walsh K, Miller RL, Semanek D, Perera F. March 2015

F344/NTac Rats Chronically Exposed to Bromodichloroacetic Acid Develop Mammary Adenocarcinomas With Mixed Luminal/Basal Phenotype and Tgfbeta Dysregulation [Abstract F344/NTac Rats Chronically Exposed to Bromodichloroacetic Acid Develop Mammary Adenocarcinomas With Mixed Luminal/Basal Phenotype and Tgfbeta Dysregulation] [Synopsis F344/NTac Rats Chronically Exposed to Bromodichloroacetic Acid Develop Mammary Adenocarcinomas With Mixed Luminal/Basal Phenotype and Tgfbeta Dysregulation] Harvey JB, Hong HH, Bhusari S, Ton TV, Wang Y, Foley JF, Peddada SD, Hooth M, DeVito M, Nyska A, Pandiri AR, Hoenerhoff MJ. March 2015

Impact of Gestational Bisphenol A on Oxidative Stress and Free Fatty Acids: Human Association and Interspecies Animal Testing Studies [Abstract Impact of Gestational Bisphenol A on Oxidative Stress and Free Fatty Acids: Human Association and Interspecies Animal Testing Studies] [Synopsis Impact of Gestational Bisphenol A on Oxidative Stress and Free Fatty Acids: Human Association and Interspecies Animal Testing Studies] Veiga-Lopez A, Pennathur S, Kannan K, Patisaul HB, Dolinoy DC, Zeng L, Padmanabhan V. March 2015

Macrophage Solubilization and Cytotoxicity of Indium-containing Particles as in Vitro Correlates to Pulmonary Toxicity in Vivo [Abstract Macrophage Solubilization and Cytotoxicity of Indium-containing Particles as in Vitro Correlates to Pulmonary Toxicity in Vivo] [Synopsis Macrophage Solubilization and Cytotoxicity of Indium-containing Particles as in Vitro Correlates to Pulmonary Toxicity in Vivo] Gwinn WM, Qu W, Bousquet RW, Price H, Shines CJ, Taylor GJ, Waalkes MP, Morgan DL. March 2015

Prenatal Exposure of Mice to the Human Liver Carcinogen Aflatoxin B1 Reveals a Critical Window of Susceptibility to Genetic Change [Abstract Prenatal Exposure of Mice to the Human Liver Carcinogen Aflatoxin B1 Reveals a Critical Window of Susceptibility to Genetic Change] [Synopsis Prenatal Exposure of Mice to the Human Liver Carcinogen Aflatoxin B1 Reveals a Critical Window of Susceptibility to Genetic Change] Chawanthayatham S, Thiantanawat A, Egner PA, Groopman JD, Wogan GN, Croy RG, Essigmann JM. March 2015

Tracking Replication Enzymology In Vivo By Genome-wide Mapping of Ribonucleotide Incorporation [Abstract Tracking Replication Enzymology In Vivo By Genome-wide Mapping of Ribonucleotide Incorporation] [Synopsis Tracking Replication Enzymology In Vivo By Genome-wide Mapping of Ribonucleotide Incorporation] Clausen AR, Lujan SA, Burkholder AB, Orebaugh CD, Williams JS, Clausen MF, Malc EP, Mieczkowski PA, Fargo DC, Smith DJ, Kunkel TA. March 2015

Complementation of Aprataxin Deficiency by Base Excision Repair Enzymes [Abstract Complementation of Aprataxin Deficiency by Base Excision Repair Enzymes] [Synopsis Complementation of Aprataxin Deficiency by Base Excision Repair Enzymes] Caglayan M, Horton JK, Prasad R, Wilson SH. February 2015

Integrative Analysis of 111 Reference Human Epigenomes [Abstract Integrative Analysis of 111 Reference Human Epigenomes] [Synopsis Integrative Analysis of 111 Reference Human Epigenomes] [Story Integrative Analysis of 111 Reference Human Epigenomes] Kundaje A, Meuleman W, Ernst J, et al. (95 authors). February 2015

Mercury Exposure and Antinuclear Antibodies Among Females of Reproductive Age in the United States: NHANES [Abstract Mercury Exposure and Antinuclear Antibodies Among Females of Reproductive Age in the United States: NHANES] [Synopsis Mercury Exposure and Antinuclear Antibodies Among Females of Reproductive Age in the United States: NHANES] Somers EC, Ganser MA, Warren JS, Basu N, Wang L, Zick SM, Park SK. February 2015

Novel Roles for Notch3 and Notch4 Receptors in Gene Expression and Susceptibility to Ozone-Induced Lung Inflammation in Mice [Abstract Novel Roles for Notch3 and Notch4 Receptors in Gene Expression and Susceptibility to Ozone-Induced Lung Inflammation in Mice] [Synopsis Novel Roles for Notch3 and Notch4 Receptors in Gene Expression and Susceptibility to Ozone-Induced Lung Inflammation in Mice] Verhein KC, McCaw Z, Gladwell W, Trivedi S, Bushel PR, Kleeberger SR. February 2015

Risk-benefit Profiles of Women Using Tamoxifen for Chemoprevention [Abstract Risk-benefit Profiles of Women Using Tamoxifen for Chemoprevention] [Synopsis Risk-benefit Profiles of Women Using Tamoxifen for Chemoprevention] Nichols HB, DeRoo LA, Scharf DR, Sandler DP. February 2015

Tetrameric Ctp1 Coordinates DNA Binding and DNA Bridging in DNA Double-Strand-Break Repair [Abstract Tetrameric Ctp1 Coordinates DNA Binding and DNA Bridging in DNA Double-Strand-Break Repair] [Synopsis Tetrameric Ctp1 Coordinates DNA Binding and DNA Bridging in DNA Double-Strand-Break Repair] [Story Tetrameric Ctp1 Coordinates DNA Binding and DNA Bridging in DNA Double-Strand-Break Repair] Andres SN, Appel CD, Westmoreland JW, Williams JS, Nguyen Y, Robertson PD, Resnick MA, Williams RS. February 2015

The Impact of Prenatal Parental Tobacco Smoking on Risk of Diabetes Mellitus in Middle-Aged Women [Abstract The Impact of Prenatal Parental Tobacco Smoking on Risk of Diabetes Mellitus in Middle-Aged Women] [Synopsis The Impact of Prenatal Parental Tobacco Smoking on Risk of Diabetes Mellitus in Middle-Aged Women] La Merrill MA, Cirillo PM, Krigbaum NY, Cohn BA. February 2015

Associations of Cadmium and Lead Exposure with Leukocyte Telomere Length: Findings from National Health and Nutrition Examination Survey, 1999-2002 [Abstract Associations of Cadmium and Lead Exposure with Leukocyte Telomere Length: Findings from National Health and Nutrition Examination Survey, 1999-2002] [Synopsis Associations of Cadmium and Lead Exposure with Leukocyte Telomere Length: Findings from National Health and Nutrition Examination Survey, 1999-2002] Zota AR, Needham BL, Blackburn EH, Lin J, Park SK, Rehkopf DH, Epel ES. January 2015

Developmental Pesticide Exposure Reproduces Features of Attention Deficit Hyperactivity Disorder [Abstract Developmental Pesticide Exposure Reproduces Features of Attention Deficit Hyperactivity Disorder] [Synopsis Developmental Pesticide Exposure Reproduces Features of Attention Deficit Hyperactivity Disorder] Richardson JR, Taylor MM, Shalat SL, Guillot TS 3rd, Caudle WM, Hossain MM, Mathews TA, Jones SR, Cory-Slechta DA, Miller GW. January 2014

Diversity Outbred Mice Identify Population-based Exposure Thresholds and Genetic Factors That Influence Benzene-induced Genotoxicity [Abstract Diversity Outbred Mice Identify Population-based Exposure Thresholds and Genetic Factors That Influence Benzene-induced Genotoxicity] [Synopsis Diversity Outbred Mice Identify Population-based Exposure Thresholds and Genetic Factors That Influence Benzene-induced Genotoxicity] French JE, Gatti DM, Morgan DL, Kissling GE, Shockley KR, Knudsen GA, Shepard KG, Price HC, King D, Witt KL, Pedersen LC, Munger SC, Svenson KL, Churchill GA. January 2015

Interactions of Chromatin Context, Binding Site Sequence Content, and Sequence Evolution in Stress-Induced p53 Occupancy and Transactivation [Abstract Interactions of Chromatin Context, Binding Site Sequence Content, and Sequence Evolution in Stress-Induced p53 Occupancy and Transactivation] [Synopsis Interactions of Chromatin Context, Binding Site Sequence Content, and Sequence Evolution in Stress-Induced p53 Occupancy and Transactivation] Su D, Wang X, Campbell MR, Song L, Safi A, Crawford GE, Bell DA. January 2015

Mouse-Human Experimental Epigenetic Analysis Unmasks Dietary Targets and Genetic Liability for Diabetic Phenotypes [Abstract Mouse-Human Experimental Epigenetic Analysis Unmasks Dietary Targets and Genetic Liability for Diabetic Phenotypes] [Synopsis Mouse-Human Experimental Epigenetic Analysis Unmasks Dietary Targets and Genetic Liability for Diabetic Phenotypes] Multhaup ML, Seldin MM, Jaffe AE, Lei X, Kirchner H, Mondal P, Li Y, Rodriguez V, Drong A, Hussain M, Lindgren C, McCarthy M, Naslund E, Zierath JR, Wong GW, Feinberg AP. January 2015

Trif-Dependent Induction of Th17 Immunity by Lung Dendritic Cells [Abstract Trif-Dependent Induction of Th17 Immunity by Lung Dendritic Cells] [Synopsis Trif-Dependent Induction of Th17 Immunity by Lung Dendritic Cells] Hsia BJ, Whitehead GS, Thomas SY, Nakano K, Gowdy KM, Aloor JJ, Nakano H, Cook DN. January 2015

A Divergent Pumilio Repeat Protein Family for Pre-rRNA Processing and mRNA Localization [Abstract A Divergent Pumilio Repeat Protein Family for Pre-rRNA Processing and mRNA Localization] [Synopsis A Divergent Pumilio Repeat Protein Family for Pre-rRNA Processing and mRNA Localization] Qiu C, McCann KL, Wine RN, Baserga SJ, Hall TM. December 2014

Autism Spectrum Disorder and Particulate Matter Air Pollution Before, During, and After Pregnancy [Abstract Autism Spectrum Disorder and Particulate Matter Air Pollution Before, During, and After Pregnancy] [Synopsis Autism Spectrum Disorder and Particulate Matter Air Pollution Before, During, and After Pregnancy] Raz R, Roberts AL, Lyall K, Hart JE, Just AC, Laden F, Weisskopf MG. December 2014

Cause-specific Risk of Hospital Admission Related to Extreme Heat in Older Adults [Abstract Cause-specific Risk of Hospital Admission Related to Extreme Heat in Older Adults] [Synopsis Cause-specific Risk of Hospital Admission Related to Extreme Heat in Older Adults] Bobb JF, Obermeyer Z, Wang Y, Dominici F. December 2014

Peritubular Myoid Cells Participate in Male Mouse Spermatogonial Stem Cell Maintenance [Abstract Peritubular Myoid Cells Participate in Male Mouse Spermatogonial Stem Cell Maintenance] [Synopsis Peritubular Myoid Cells Participate in Male Mouse Spermatogonial Stem Cell Maintenance] Chen LY, Brown PR, Willis WB, Eddy EM. December 2014

Persistent Associations between Maternal Prenatal Exposure to Phthalates on Child IQ at Age 7 Years [Abstract Persistent Associations between Maternal Prenatal Exposure to Phthalates on Child IQ at Age 7 Years] [Synopsis Persistent Associations between Maternal Prenatal Exposure to Phthalates on Child IQ at Age 7 Years] Factor-Litvak P, Insel B, Calafat AM, Liu X, Perera F, Rauh VA, Whyatt RM. December 2014

Preconception Serum 1,1,1-trichloro-2,2,bis(p-chlorophenyl)ethane and B-Vitamin Status: Independent and Joint Effects on Women’s Reproductive Outcomes [Abstract Preconception Serum 1,1,1-trichloro-2,2,bis(p-chlorophenyl)ethane and B-Vitamin Status: Independent and Joint Effects on Women’s Reproductive Outcomes] [Synopsis Preconception Serum 1,1,1-trichloro-2,2,bis(p-chlorophenyl)ethane and B-Vitamin Status: Independent and Joint Effects on Women’s Reproductive Outcomes] Ouyang F, Longnecker MP, Venners SA, Johnson S, Korrick S, Zhang J, Xu X, Christian P, Wang MC, Wang X. December 2014

The Commonly Used Antimicrobial Additive Triclosan is a Liver Tumor Promoter [Abstract The Commonly Used Antimicrobial Additive Triclosan is a Liver Tumor Promoter] [Synopsis The Commonly Used Antimicrobial Additive Triclosan is a Liver Tumor Promoter] [Story The Commonly Used Antimicrobial Additive Triclosan is a Liver Tumor Promoter] Yueh MF, Taniguchi K, Chen S, Evans RM, Hammock BD, Karin M, Tukey RH. December 2014

The Concordance Between RNA-seq and Microarray Data Depends on Chemical Treatment and Transcript Abundance [Abstract The Concordance Between RNA-seq and Microarray Data Depends on Chemical Treatment and Transcript Abundance] [Synopsis The Concordance Between RNA-seq and Microarray Data Depends on Chemical Treatment and Transcript Abundance] Wang C, Gong B, Bushel PR, Thierry-Mieg J, Thierry-Mieg D, Xu J, Fang H, Hong H, Shen J, Su Z, Meehan J, Li X, Yang L, Li H, Labaj PP, Kreil DP, Megherbi D, Gaj S, Caiment F, van Delft J, Kleinjans J, Scherer A, Devanarayan V, Wang J, Yang Y, Qian HR, Lancashire LJ, Bessarabova M, Nikolsky Y, Furlanello C, Chierici M, Albanese D, Jurman G, Riccadonna S, Filosi M, Visintainer R, Zhang KK, Li J, Hsieh JH, Svoboda DL, Fuscoe JC, Deng Y, Shi L, Paules RS, Auerbach SS, Tong W. December 2014

Uterine Epithelial Cell Estrogen Receptor Alpha-dependent and -independent Genomic Profiles that Underlie Estrogen Responses in Mice [Abstract Uterine Epithelial Cell Estrogen Receptor Alpha-dependent and -independent Genomic Profiles that Underlie Estrogen Responses in Mice] [Synopsis Uterine Epithelial Cell Estrogen Receptor Alpha-dependent and -independent Genomic Profiles that Underlie Estrogen Responses in Mice] Winuthayanon W, Hewitt SC, Korach KS. December 2014

A Population-Based Case-Control Study of Urinary Bisphenol A Concentrations and Risk of Endometriosis [Abstract A Population-Based Case-Control Study of Urinary Bisphenol A Concentrations and Risk of Endometriosis] [Synopsis A Population-Based Case-Control Study of Urinary Bisphenol A Concentrations and Risk of Endometriosis] Upson K, Sathyanarayana S, De Roos AJ, Koch HM, Scholes D, Holt VL. November 2014

Application of Sholl Analysis to Quantify Changes in Growth and Development in Rat Mammary Gland Whole Mounts [Abstract Application of Sholl Analysis to Quantify Changes in Growth and Development in Rat Mammary Gland Whole Mounts] [Synopsis Application of Sholl Analysis to Quantify Changes in Growth and Development in Rat Mammary Gland Whole Mounts] Stanko JP, Easterling MR, Fenton SE. November 2014

A Short-term in Vivo Screen Using Fetal Testosterone Production, a Key Event in the Phthalate Adverse Outcome Pathway, to Predict Disruption of Sexual Differentiation [Abstract A Short-term in Vivo Screen Using Fetal Testosterone Production, a Key Event in the Phthalate Adverse Outcome Pathway, to Predict Disruption of Sexual Differentiation] [Synopsis A Short-term in Vivo Screen Using Fetal Testosterone Production, a Key Event in the Phthalate Adverse Outcome Pathway, to Predict Disruption of Sexual Differentiation] Furr JR, Lambright CS, Wilson VS, Foster PM, Gray LE Jr. November 2014

Association of Nrf2 Polymorphism Haplotypes with Acute Lung Injury Phenotypes in Inbred Strains of Mice [Abstract Association of Nrf2 Polymorphism Haplotypes with Acute Lung Injury Phenotypes in Inbred Strains of Mice] [Synopsis Association of Nrf2 Polymorphism Haplotypes with Acute Lung Injury Phenotypes in Inbred Strains of Mice] Cho HY, Jedlicka AE, Gladwell W, Marzec J, McCaw ZR, Bienstock RJ, Kleeberger SR. November 2014

Association of Systemic Lupus Erythematosus With Uranium Exposure in a Community Living Near a Uranium-Processing Plant: A Nested Case-Control Study [Abstract Association of Systemic Lupus Erythematosus With Uranium Exposure in a Community Living Near a Uranium-Processing Plant: A Nested Case-Control Study] [Synopsis Association of Systemic Lupus Erythematosus With Uranium Exposure in a Community Living Near a Uranium-Processing Plant: A Nested Case-Control Study] Lu-Fritts PY, Kottyan LC, James JA, Xie C, Buckholz JM, Pinney SM, Harley JB. November 2014

Drp1 Inhibition Attenuates Neurotoxicity and Dopamine Release Deficits In Vivo [Abstract Drp1 Inhibition Attenuates Neurotoxicity and Dopamine Release Deficits In Vivo] [Synopsis Drp1 Inhibition Attenuates Neurotoxicity and Dopamine Release Deficits In Vivo] Rappold PM, Cui M, Grima JC, Fan RZ, de Mesy-Bentley KL, Chen L, Zhuang X, Bowers WJ, Tieu K. November 2014

Epigenetic Modification of Histone 3 Lysine 27: Mediator Subunit MED25 is Required for the Dissociation of Polycomb Repressive Complex 2 from the Promoter of Cytochrome P450 2C9 [Abstract Epigenetic Modification of Histone 3 Lysine 27: Mediator Subunit MED25 is Required for the Dissociation of Polycomb Repressive Complex 2 from the Promoter of Cytochrome P450 2C9] [Synopsis Epigenetic Modification of Histone 3 Lysine 27: Mediator Subunit MED25 is Required for the Dissociation of Polycomb Repressive Complex 2 from the Promoter of Cytochrome P450 2C9] Englert NA, Luo G, Goldstein JA, Surapureddi S. November 2014

Global Analysis of Posttranscriptional Gene Expression in Response to Sodium Arsenite [Abstract Global Analysis of Posttranscriptional Gene Expression in Response to Sodium Arsenite] [Synopsis Global Analysis of Posttranscriptional Gene Expression in Response to Sodium Arsenite] Qiu LQ, Abey S, Harris S, Shah R, Gerrish KE, Blackshear PJ. November 2014

Maternal Hyperglycemia During Pregnancy Predicts Adiposity of the Offspring [Abstract Maternal Hyperglycemia During Pregnancy Predicts Adiposity of the Offspring] [Synopsis Maternal Hyperglycemia During Pregnancy Predicts Adiposity of the Offspring] Kubo A, Ferrara A, Windham GC, Greenspan LC, Deardorff J, Hiatt RA, Quesenberry CP Jr, Laurent C, Mirabedi AS, Kushi LH. November 2014

Natural Selection Canalizes Expression Variation of Environmentally Induced Plasticity-Enabling Genes [Abstract Natural Selection Canalizes Expression Variation of Environmentally Induced Plasticity-Enabling Genes] [Synopsis Natural Selection Canalizes Expression Variation of Environmentally Induced Plasticity-Enabling Genes] Shaw JR, Hampton TH, King BL, Whitehead A, Galvez F, Gross RH, Keith N, Notch E, Jung D, Glaholt SP, Chen CY, Colbourne JK, Stanton BA. November 2014

Uncovering the Polymerase-Induced Cytotoxicity of an Oxidized Nucleotide [Abstract Uncovering the Polymerase-Induced Cytotoxicity of an Oxidized Nucleotide] [Synopsis Uncovering the Polymerase-Induced Cytotoxicity of an Oxidized Nucleotide] [Story Uncovering the Polymerase-Induced Cytotoxicity of an Oxidized Nucleotide] Freudenthal BD, Beard WA, Perera L, Shock DD, Kim T, Schlick T, Wilson SH. November 2014

Urinary Biomonitoring of Phosphate Flame Retardants: Levels in California Adults and Recommendations for Future Studies [Abstract Urinary Biomonitoring of Phosphate Flame Retardants: Levels in California Adults and Recommendations for Future Studies] [Synopsis Urinary Biomonitoring of Phosphate Flame Retardants: Levels in California Adults and Recommendations for Future Studies] Dodson RE, Van den Eede N, Covaci A, Perovich LJ, Brody JG, Rudel RA. November 2014

Ambient Air Pollution Exposure and Incident Adult Asthma in a Nationwide Cohort of U.S. Women [Abstract Ambient Air Pollution Exposure and Incident Adult Asthma in a Nationwide Cohort of U.S. Women] [Synopsis Ambient Air Pollution Exposure and Incident Adult Asthma in a Nationwide Cohort of U.S. Women] Young MT, Sandler DP, DeRoo LA, Vedal S, Kaufman JD, London SJ. October 2014

A Targeted Health Risk Assessment Following the Deep Water Horizon Oil Spill: Polycyclic Aromatic Hydrocarbon Exposure in Vietnamese-American Shrimp Consumers [Abstract A Targeted Health Risk Assessment Following the Deep Water Horizon Oil Spill: Polycyclic Aromatic Hydrocarbon Exposure in Vietnamese-American Shrimp Consumers] [Synopsis A Targeted Health Risk Assessment Following the Deep Water Horizon Oil Spill: Polycyclic Aromatic Hydrocarbon Exposure in Vietnamese-American Shrimp Consumers] Wilson MJ, Frickel S, Nguyen D, Bui T, Echsner S, Simon BR, Howard JL, Miller K, Wickliffe JK. October 2014

Endocrine Disruption in Human Placenta: Expression of the Dioxin-Inducible Enzyme, Cyp1a1, Is Correlated With That of Thyroid Hormone-Regulated Genes [Abstract Endocrine Disruption in Human Placenta: Expression of the Dioxin-Inducible Enzyme, Cyp1a1, Is Correlated With That of Thyroid Hormone-Regulated Genes] [Synopsis Endocrine Disruption in Human Placenta: Expression of the Dioxin-Inducible Enzyme, Cyp1a1, Is Correlated With That of Thyroid Hormone-Regulated Genes] Wadzinski TL, Geromini K, McKinley Brewer J, Bansal R, Abdelouahab N, Langlois MF, Takser L, Zoeller RT. October 2014

Key Role For Scavenger Receptor B-I in the Integrative Physiology of Host Defense During Bacterial Pneumonia [Abstract Key Role For Scavenger Receptor B-I in the Integrative Physiology of Host Defense During Bacterial Pneumonia] [Synopsis Key Role For Scavenger Receptor B-I in the Integrative Physiology of Host Defense During Bacterial Pneumonia] Gowdy KM, Madenspacher JH, Azzam KM, Gabor KA, Janardhan KS, Aloor JJ, Fessler MB. October 2014

MMS Exposure Promotes Increased mtDNA Mutagenesis in the Presence of Replication-Defective Disease-Associated DNA Polymerase Gamma Variants [Abstract MMS Exposure Promotes Increased mtDNA Mutagenesis in the Presence of Replication-Defective Disease-Associated DNA Polymerase Gamma Variants] [Synopsis MMS Exposure Promotes Increased mtDNA Mutagenesis in the Presence of Replication-Defective Disease-Associated DNA Polymerase Gamma Variants] Stumpf JD, Copeland WC. October 2014

Role of the Vasopressin 1b Receptor in Rodent Aggressive Behavior and Synaptic Plasticity in Hippocampal Area CA2 [Abstract Role of the Vasopressin 1b Receptor in Rodent Aggressive Behavior and Synaptic Plasticity in Hippocampal Area CA2] [Synopsis Role of the Vasopressin 1b Receptor in Rodent Aggressive Behavior and Synaptic Plasticity in Hippocampal Area CA2] Pagani JH, Zhao M, Cui Z, Williams Avram SK, Caruana DA, Dudek SM, Young WS. October 2014

Epistemology of Contaminants of Emerging Concern and Literature Meta-Analysis [Abstract Epistemology of Contaminants of Emerging Concern and Literature Meta-Analysis] [Synopsis Epistemology of Contaminants of Emerging Concern and Literature Meta-Analysis] Halden RU. September 2014

Heterogeneous Polymerase Fidelity and Mismatch Repair Bias Genome Variation and Composition [Abstract Heterogeneous Polymerase Fidelity and Mismatch Repair Bias Genome Variation and Composition] [Synopsis Heterogeneous Polymerase Fidelity and Mismatch Repair Bias Genome Variation and Composition] Lujan SA, Clausen AR, Clark AB, MacAlpine HK, MacAlpine DM, Malc EP, Mieczkowski PA, Burkholder AB, Fargo DC, Gordenin DA, Kunkel TA. September 2014

Histone-Fold Domain Protein NF-Y Promotes Chromatin Accessibility for Cell Type-Specific Master Transcription Factors [Abstract Histone-Fold Domain Protein NF-Y Promotes Chromatin Accessibility for Cell Type-Specific Master Transcription Factors] [Synopsis Histone-Fold Domain Protein NF-Y Promotes Chromatin Accessibility for Cell Type-Specific Master Transcription Factors] Oldfield AJ, Yang P, Conway AE, Cinghu S, Freudenberg JM, Yellaboina S, Jothi R. September 2014

Pesticide Exposure and Depression Among Male Private Pesticide Applicators in the Agricultural Health Study [Abstract Pesticide Exposure and Depression Among Male Private Pesticide Applicators in the Agricultural Health Study] [Synopsis Pesticide Exposure and Depression Among Male Private Pesticide Applicators in the Agricultural Health Study] Beard JD, Umbach DM, Hoppin JA, Richards M, Alavanja MC, Blair A, Sandler DP, Kamel F. September 2014

Predicting the Human Epigenome from DNA Motifs [Abstract Predicting the Human Epigenome from DNA Motifs] [Synopsis Predicting the Human Epigenome from DNA Motifs] Whitaker JW, Chen Z, Wang W. September 2014

RORalpha and RORgamma Are Expressed in Human Skin and Serve as Receptors for Endogenously Produced Noncalcemic 20-hydroxy- and 20,23-dihyroxyvitamin D [Abstract RORalpha and RORgamma Are Expressed in Human Skin and Serve as Receptors for Endogenously Produced Noncalcemic 20-hydroxy- and 20,23-dihyroxyvitamin D] [Synopsis RORalpha and RORgamma Are Expressed in Human Skin and Serve as Receptors for Endogenously Produced Noncalcemic 20-hydroxy- and 20,23-dihyroxyvitamin D] Slominski AT, Kim TK, Takeda Y, Janjetovic Z, Brozyna AA, Skobowiat C, Wang J, Postlethwaite A, Li W, Tuckey RC, Jetten AM. September 2014

SIRT-1-Mediated Deacetylation of CRABPII Regulates Cellular Retinoic Acid Signaling and Modulates Embryonic Stem Cell Differentiation [Abstract SIRT-1-Mediated Deacetylation of CRABPII Regulates Cellular Retinoic Acid Signaling and Modulates Embryonic Stem Cell Differentiation] [Synopsis SIRT-1-Mediated Deacetylation of CRABPII Regulates Cellular Retinoic Acid Signaling and Modulates Embryonic Stem Cell Differentiation] Tang S, Huang G, Fan W, Chen Y, Ward JM, Xu X, Xu Q, Kang A, McBurney MW, Fargo DC, Hu G, Baumgart-Vogt E, Zhao Y, Li X. September 2014

Substance P Exacerbates Dopaminergic Neurodegeneration Through Neurokinin-1 Receptor-Independent Activation of Microglial NADPH Oxidase [Abstract Substance P Exacerbates Dopaminergic Neurodegeneration Through Neurokinin-1 Receptor-Independent Activation of Microglial NADPH Oxidase] [Synopsis Substance P Exacerbates Dopaminergic Neurodegeneration Through Neurokinin-1 Receptor-Independent Activation of Microglial NADPH Oxidase] Wang Q, Chu CH, Qian L, Chen SH, Wilson B, Oyarzabal E, Jiang L, Ali S, Robinson B, Kim HC, Hong JS. September 2014

Twin and Family Studies Reveal Strong Environmental and Weaker Genetic Cues Explaining Heritability of Eosinophilic Esophagitis [Abstract Twin and Family Studies Reveal Strong Environmental and Weaker Genetic Cues Explaining Heritability of Eosinophilic Esophagitis] [Synopsis Twin and Family Studies Reveal Strong Environmental and Weaker Genetic Cues Explaining Heritability of Eosinophilic Esophagitis] Alexander ES, Martin LJ, Collins MH, Kottyan LC, Sucharew H, He H, Mukkada VA, Succop PA, Abonia JP, Foote H, Eby MD, Grotjan TM, Greenler AJ, Dellon ES, Demain JG, Furuta GT, Gurian LE, Harley JB, Hopp RJ, Kagalwalla A, Kaul A, Nadeau KC, Noel RJ, Putnam PE, von Tiehl KF, Rothenberg ME. September 2014

Biosynthesis of Polybrominated Aromatic Organic Compounds by Marine Bacteria [Abstract Biosynthesis of Polybrominated Aromatic Organic Compounds by Marine Bacteria] [Synopsis Biosynthesis of Polybrominated Aromatic Organic Compounds by Marine Bacteria] Agarwal V, El Gamal AA, Yamanaka K, Poth D, Kersten RD, Schorn M, Allen EE, Moore BS. August 2014

Genistein Disrupts Glucocorticoid Receptor Signaling in Human Uterine Endometrial Ishikawa Cells [Abstract Genistein Disrupts Glucocorticoid Receptor Signaling in Human Uterine Endometrial Ishikawa Cells] [Synopsis Genistein Disrupts Glucocorticoid Receptor Signaling in Human Uterine Endometrial Ishikawa Cells] Whirledge S, Senbanjo LT, Cidlowski JA. August 2014

Genome-wide Association Analysis Identifies Six New Loci Associated with Forced Vital Capacity [Abstract Genome-wide Association Analysis Identifies Six New Loci Associated with Forced Vital Capacity] [Synopsis Genome-wide Association Analysis Identifies Six New Loci Associated with Forced Vital Capacity] Loth DW, Artigas MS, Gharib SA, Wain LV, Franceschini N, Koch B, Pottinger TD, Smith AV, Duan Q, Oldmeadow C, Lee MK, Strachan DP, James AL, Huffman JE, Vitart V, Ramasamy A, Wareham NJ, Kaprio J, Wang XQ, Trochet H, Kahonen M, Flexeder C, Albrecht E, Lopez LM, de Jong K, Thyagarajan B, Alves AC, Enroth S, Omenaas E, Joshi PK, Fall T, Vinuela A, Launer LJ, Loehr LR, Fornage M, Li G, Wilk JB, Tang W, Manichaikul A, Lahousse L, Harris TB, North KE, Rudnicka AR, Hui J, Gu X, Lumley T, Wright AF, Hastie ND, Campbell S, Kumar R, Pin I, Scott RA, Pietilainen KH, Surakka I, Liu Y, Holliday EG, Schulz H, Heinrich J, Davies G, Vonk JM, Wojczynski M, Pouta A, Johansson A, Wild SH, Ingelsson E, Rivadeneira F, Volzke H, Hysi PG, Eiriksdottir G, Morrison AC, Rotter JI, Gao W, Postma DS, White WB, Rich SS, Hofman A, Aspelund T, Couper D, Smith LJ, Psaty BM, Lohman K, Burchard EG, Uitterlinden AG, Garcia M, Joubert BR, McArdle WL, Musk AB, Hansel N, Heckbert SR, Zgaga L, van Meurs JB, Navarro P, Rudan I, Oh YM, Redline S, Jarvis DL, Zhao JH, Rantanen T, O'Connor GT, Ripatti S, Scott RJ, Karrasch S, Grallert H, Gaddis NC, Starr JM, Wijmenga C, Minster RL, Lederer DJ, Pekkanen J, Gyllensten U, Campbell H, Morris AP, Glaser S, Hammond CJ, Burkart KM, Beilby J, Kritchevsky SB, Gudnason V, Hancock DB, Williams OD, Polasek O, Zemunik T, Kolcic I, Petrini MF, Wjst M, Kim WJ, Porteous DJ, Scotland G, Smith BH, Viljanen A, Heliovaara M, Attia JR, Sayers I, Hampel R, Gieger C, Deary IJ, Boezen HM, Newman A, Jarvelin MR, Wilson JF, Lind L, Stricker BH, Teumer A, Spector TD, Melen E, Peters MJ, Lange LA, Barr RG, Bracke KR, Verhamme FM, Sung J, Hiemstra PS, Cassano PA, Sood A, Hayward C, Dupuis J, Hall IP, Brusselle GG, Tobin MD, London SJ. August 2014

Lung Tumors in Mice Induced by “Whole Life” Inorganic Arsenic Exposure at Human-Relevant Doses [Abstract Lung Tumors in Mice Induced by “Whole Life” Inorganic Arsenic Exposure at Human-Relevant Doses] [Synopsis Lung Tumors in Mice Induced by “Whole Life” Inorganic Arsenic Exposure at Human-Relevant Doses] [Story Lung Tumors in Mice Induced by “Whole Life” Inorganic Arsenic Exposure at Human-Relevant Doses] Waalkes MP, Qu W, Tokar EJ, Kissling GE, Dixon D. August 2014

Perinatal Lead (Pb) Exposure Results in Sex-Specific Effects on Food Intake, Fat, Weight, and Insulin Response Across the Murine Life-Course [Abstract Perinatal Lead (Pb) Exposure Results in Sex-Specific Effects on Food Intake, Fat, Weight, and Insulin Response Across the Murine Life-Course] [Synopsis Perinatal Lead (Pb) Exposure Results in Sex-Specific Effects on Food Intake, Fat, Weight, and Insulin Response Across the Murine Life-Course] Faulk C, Barks A, Sanchez BN, Zhang Z, Anderson OS, Peterson KE, Dolinoy DC. August 2014

Rapid and Sustainable Detoxication of Airborne Pollutants by Broccoli Sprout Beverage: Results of a Randomized Clinical Trial in China [Abstract Rapid and Sustainable Detoxication of Airborne Pollutants by Broccoli Sprout Beverage: Results of a Randomized Clinical Trial in China] [Synopsis Rapid and Sustainable Detoxication of Airborne Pollutants by Broccoli Sprout Beverage: Results of a Randomized Clinical Trial in China] Egner PA, Chen JG, Zarth AT, Ng DK, Wang JB, Kensler KH, Jacobson LP, Munoz A, Johnson JL, Groopman JD, Fahey JW, Talalay P, Zhu J, Chen TY, Qian GS, Carmella SG, Hecht SS, Kensler TW. August 2014

Retinoid Acid-Related Orphan Receptor Gamma, RORGamma, Participates in Diurnal Transcriptional Regulation of Lipid Metabolic Genes [Abstract Retinoid Acid-Related Orphan Receptor Gamma, RORGamma, Participates in Diurnal Transcriptional Regulation of Lipid Metabolic Genes] [Synopsis Retinoid Acid-Related Orphan Receptor Gamma, RORGamma, Participates in Diurnal Transcriptional Regulation of Lipid Metabolic Genes] Takeda Y, Kang HS, Lih FB, Jiang H, Blaner WS, Jetten AM. August 2014

Aryl Hydrocarbon Receptor Control of a Disease Tolerance Defence Pathway [Abstract Aryl Hydrocarbon Receptor Control of a Disease Tolerance Defence Pathway] [Synopsis Aryl Hydrocarbon Receptor Control of a Disease Tolerance Defence Pathway] Bessede A, Gargaro M, Pallotta MT, Matino D, Servillo G, Brunacci C, Bicciato S, Mazza EM, Machiarulo A, Vacca C, Iannitti R, Tissi L, Volpi C, Belladonna ML, Orabona C, Bianchi R, Lanz TV, Platten M, Della Fazia MA, Piobbico D, Zelante T, Funakoshi H, Nakamura T, Gilot D, Denison MS, Guillemin GJ, DuHadaway JB, Prendergast GC, Metz R, Geffard M, Boon L, Pirro M, Iorio A, Veyret B, Romani L, Grohmann U, Fallarino F, Puccetti P. July 2014

Avoidance of Ribonucleotide-Induced Mutations by RNase H2 and Srs2-Exo1 Mechanisms [Abstract Avoidance of Ribonucleotide-Induced Mutations by RNase H2 and Srs2-Exo1 Mechanisms] [Synopsis Avoidance of Ribonucleotide-Induced Mutations by RNase H2 and Srs2-Exo1 Mechanisms] Potenski CJ, Niu H, Sung P, Klein HL. July 2014

Catalytic Antioxidant AEOL 10150 Treatment Ameliorates Sulfur Mustard Analog 2-Chloroethyl Ethyl Sulfide-Associated Cutaneous Toxic Effects [Abstract Catalytic Antioxidant AEOL 10150 Treatment Ameliorates Sulfur Mustard Analog 2-Chloroethyl Ethyl Sulfide-Associated Cutaneous Toxic Effects] [Synopsis Catalytic Antioxidant AEOL 10150 Treatment Ameliorates Sulfur Mustard Analog 2-Chloroethyl Ethyl Sulfide-Associated Cutaneous Toxic Effects] Tewari-Singh N, Inturi S, Jain AK, Agarwal C, Orlicky DJ, White CW, Agarwal R, Day BJ. July 2014

DNA Methylation Dynamics of the Human Preimplantation Embryo [Abstract DNA Methylation Dynamics of the Human Preimplantation Embryo] [Synopsis DNA Methylation Dynamics of the Human Preimplantation Embryo] Smith ZD, Chan MM, Humm KC, Karnik R, Mekhoubad S, Regev A, Eggan K, Meissner A. July 2014

Increased Vesicular Monoamine Transporter Enhances Dopamine Release and Opposes Parkinson Disease-Related Neurodegeneration In Vivo [Abstract Increased Vesicular Monoamine Transporter Enhances Dopamine Release and Opposes Parkinson Disease-Related Neurodegeneration In Vivo] [Synopsis Increased Vesicular Monoamine Transporter Enhances Dopamine Release and Opposes Parkinson Disease-Related Neurodegeneration In Vivo] Lohr KM, Bernstein AI, Stout KA, Dunn AR, Lazo CR, Alter SP, Wang M, Li Y, Fan X, Hess EJ, Yi H, Vecchio LM, Goldstein DS, Guillot TS, Salahpour A, Miller GW. July 2014

Molecular Mechanisms for the Regulation of Histone mRNA Stem-Loop-Binding Protein by Phosphorylation [Abstract Molecular Mechanisms for the Regulation of Histone mRNA Stem-Loop-Binding Protein by Phosphorylation] [Synopsis Molecular Mechanisms for the Regulation of Histone mRNA Stem-Loop-Binding Protein by Phosphorylation] Zhang J, Tan D, DeRose EF, Perera L, Dominski Z, Marzluff WF, Tong L, Hall TM. July 2014

Perinatal Exposure of Mice to the Pesticide DDT Impairs Energy Expenditure and Metabolism in Adult Female Offspring [Abstract Perinatal Exposure of Mice to the Pesticide DDT Impairs Energy Expenditure and Metabolism in Adult Female Offspring] [Synopsis Perinatal Exposure of Mice to the Pesticide DDT Impairs Energy Expenditure and Metabolism in Adult Female Offspring] La Merrill M, Karey E, Moshier E, Lindtner C, La Frano MR, Newman JW, Buettner C. July 2014

Pesticide Methoxychlor Promotes the Epigenetic Transgenerational Inheritance of Adult-Onset Disease through the Female Germline [Abstract Pesticide Methoxychlor Promotes the Epigenetic Transgenerational Inheritance of Adult-Onset Disease through the Female Germline] [Synopsis Pesticide Methoxychlor Promotes the Epigenetic Transgenerational Inheritance of Adult-Onset Disease through the Female Germline] Manikkam M, Haque MM, Guerrero-Bosagna C, Nilsson EE, Skinner MK. July 2014

Selective Unfolding of One Ribonuclease H Domain of HIV Reverse Transcriptase Is Linked to Homodimer Formation [Abstract Selective Unfolding of One Ribonuclease H Domain of HIV Reverse Transcriptase Is Linked to Homodimer Formation] [Synopsis Selective Unfolding of One Ribonuclease H Domain of HIV Reverse Transcriptase Is Linked to Homodimer Formation] Zheng X, Pedersen LC, Gabel SA, Mueller GA, Cuneo MJ, Derose EF, Krahn JM, London RE. July 2014

Simvastatin and Dipentyl Phthalate Lower Ex Vivo Testicular Testosterone Production and Exhibit Additive Effects on Testicular Testosterone and Gene Expression Via Distinct Mechanistic Pathways in the Fetal Rat [Abstract Simvastatin and Dipentyl Phthalate Lower Ex Vivo Testicular Testosterone Production and Exhibit Additive Effects on Testicular Testosterone and Gene Expression Via Distinct Mechanistic Pathways in the Fetal Rat] [Synopsis Simvastatin and Dipentyl Phthalate Lower Ex Vivo Testicular Testosterone Production and Exhibit Additive Effects on Testicular Testosterone and Gene Expression Via Distinct Mechanistic Pathways in the Fetal Rat] Beverly BE, Lambright CS, Furr JR, Sampson H, Wilson VS, McIntyre BS, Foster PM, Travlos G, Gray LE Jr. July 2014

Systemic Review and Evidence Integration for Literature-based Environmental Health Science Assessments [Abstract Systemic Review and Evidence Integration for Literature-based Environmental Health Science Assessments] [Synopsis Systemic Review and Evidence Integration for Literature-based Environmental Health Science Assessments] Rooney AA, Boyles AL, Wolfe MS, Bucher JR, Thayer KA. July 2014

Association Between Global Biomarkers of Oxidative Stress and Hip Fracture in Postmenopausal Women: A Prospective Study [Abstract Association Between Global Biomarkers of Oxidative Stress and Hip Fracture in Postmenopausal Women: A Prospective Study] [Synopsis Association Between Global Biomarkers of Oxidative Stress and Hip Fracture in Postmenopausal Women: A Prospective Study] Yang S, Feskanich D, Willett WC, Eliassen AH, Wu T. June 2014

Breast Cancer Risk After Occupational Solvent Exposure: The Influence of Timing and Setting [Abstract Breast Cancer Risk After Occupational Solvent Exposure: The Influence of Timing and Setting] [Synopsis Breast Cancer Risk After Occupational Solvent Exposure: The Influence of Timing and Setting] Ekenga CC, Parks CG, D’Aloisio AA, DeRoo LA, Sandler DP. June 2014

Defining Estrogenic Mechanisms of Bisphenol A Analogs through High Throughput Microscopy-based Contextual Assays [Abstract Defining Estrogenic Mechanisms of Bisphenol A Analogs through High Throughput Microscopy-based Contextual Assays] [Synopsis Defining Estrogenic Mechanisms of Bisphenol A Analogs through High Throughput Microscopy-based Contextual Assays] Stossi F, Bolt MJ, Ashcroft FJ, Lamerdin JE, Melnick JS, Powell RT, Dandekar RD, Mancini MG, Walker CL, Westwick JK, Mancini MA. June 2014

Early Postnatal Exposure to Ultrafine Particulate Matter Air Pollution: Persistent Ventriculomegaly, Neurochemical Disruption, and Glial Activation Preferentially in Male Mice [Abstract Early Postnatal Exposure to Ultrafine Particulate Matter Air Pollution: Persistent Ventriculomegaly, Neurochemical Disruption, and Glial Activation Preferentially in Male Mice] [Synopsis Early Postnatal Exposure to Ultrafine Particulate Matter Air Pollution: Persistent Ventriculomegaly, Neurochemical Disruption, and Glial Activation Preferentially in Male Mice] Allen JL, Liu X, Pelkowski S, Palmer B, Conrad K, Oberdorster G, Weston D, Mayer-Proschel M, Cory-Slechta DA. June 2014

Identification of DNA Methylation Changes in Newborns Related to Maternal Smoking during Pregnancy [Abstract Identification of DNA Methylation Changes in Newborns Related to Maternal Smoking during Pregnancy] [Synopsis Identification of DNA Methylation Changes in Newborns Related to Maternal Smoking during Pregnancy] Markunas CA, Xu Z, Harlid S, Wade PA, Lie RT, Taylor JA, Wilcox AJ. June 2014

Inflammasome Activation in Airway Epithelial Cells After Multi-Walled Carbon Nanotube Exposure Mediates a Profibrotic Response in Lung Fibroblasts [Abstract Inflammasome Activation in Airway Epithelial Cells After Multi-Walled Carbon Nanotube Exposure Mediates a Profibrotic Response in Lung Fibroblasts] [Synopsis Inflammasome Activation in Airway Epithelial Cells After Multi-Walled Carbon Nanotube Exposure Mediates a Profibrotic Response in Lung Fibroblasts] Hussain S, Sangtian S, Anderson SM, Snyder RJ, Marshburn JD, Rice AB, Bonner JC, Garantziotis S. June 2014

IP6K Structure and the Molecular Determinants of Catalytic Specificity in an Inositol Phosphate Kinase Family [Abstract IP6K Structure and the Molecular Determinants of Catalytic Specificity in an Inositol Phosphate Kinase Family] [Synopsis IP6K Structure and the Molecular Determinants of Catalytic Specificity in an Inositol Phosphate Kinase Family] Wang H, DeRose EF, London RE, Shears SB. June 2014

Nrf2 Upregulates ATP Binding Cassette Transporter Expression and Activity at the Blood-Brain and Blood-Spinal Cord Barriers [Abstract Nrf2 Upregulates ATP Binding Cassette Transporter Expression and Activity at the Blood-Brain and Blood-Spinal Cord Barriers] [Synopsis Nrf2 Upregulates ATP Binding Cassette Transporter Expression and Activity at the Blood-Brain and Blood-Spinal Cord Barriers] Wang X, Campos CR, Pert JC, Smith LK, Boni JL, Cannon RE, Miller DS. June 2014

dGTP Starvation in Escherichia Coli Provides New Insights Into the Thymineless-Death Phenomenon [Abstract dGTP Starvation in Escherichia Coli Provides New Insights Into the Thymineless-Death Phenomenon] [Synopsis dGTP Starvation in Escherichia Coli Provides New Insights Into the Thymineless-Death Phenomenon] Itsko M, Schaaper RM. May 2014

Distribution, Recognition and Regulation of Non-CpG Methylation in the Adult Mammalian Brain [Abstract Distribution, Recognition and Regulation of Non-CpG Methylation in the Adult Mammalian Brain] [Synopsis Distribution, Recognition and Regulation of Non-CpG Methylation in the Adult Mammalian Brain] Guo JU, Su Y, Shin JH, Shin J, Li H, Xie B, Zhong C, Hu S, Le T, Fan G, Zhu H, Chang Q, Gao Y, Ming GL, Song H. May 2014

INO80 Facilitates Pluripotency Gene Activation in Embryonic Stem Cell Self-renewal, Reprogramming, and Blastocyst Development [Abstract INO80 Facilitates Pluripotency Gene Activation in Embryonic Stem Cell Self-renewal, Reprogramming, and Blastocyst Development] [Synopsis INO80 Facilitates Pluripotency Gene Activation in Embryonic Stem Cell Self-renewal, Reprogramming, and Blastocyst Development] Wang L, Du Y, Ward JM, Shimbo T, Lackford B, Zheng X, Miao YL, Zhou B, Han L, Fargo DC, Jothi R, Williams CJ, Wade PA, Hu G. May 2014

Lower NLRP3 Inflammasome Activity in NAG-1 Transgenic Mice Is Linked To a Resistance To Obesity and Increased Insulin Sensitivity [Abstract Lower NLRP3 Inflammasome Activity in NAG-1 Transgenic Mice Is Linked To a Resistance To Obesity and Increased Insulin Sensitivity] [Synopsis Lower NLRP3 Inflammasome Activity in NAG-1 Transgenic Mice Is Linked To a Resistance To Obesity and Increased Insulin Sensitivity] Wang X, Chrysovergis K, Kosak J, Eling TE. May 2014

Obesity, Rather than Diet, Drives Epigenomic Alterations in Colonic Epithelium Resembling Cancer Progression [Abstract Obesity, Rather than Diet, Drives Epigenomic Alterations in Colonic Epithelium Resembling Cancer Progression] [Synopsis Obesity, Rather than Diet, Drives Epigenomic Alterations in Colonic Epithelium Resembling Cancer Progression] Li R, Grimm SA, Chrysovergis K, Kosak K, Wang X, Du Y, Burkholder A, Janardhan K, Mav D, Shah R, Eling TE, Wade PA. May 2014

Prenatal Polybrominated Diphenyl Ether Exposures and Neurodevelopment in U.S. Children Through 5 Years of Age: The HOME Study [Abstract Prenatal Polybrominated Diphenyl Ether Exposures and Neurodevelopment in U.S. Children Through 5 Years of Age: The HOME Study] [Synopsis Prenatal Polybrominated Diphenyl Ether Exposures and Neurodevelopment in U.S. Children Through 5 Years of Age: The HOME Study] Chen A, Yolton K, Rauch SA, Webster GM, Hornung R, Sjodin A, Dietrich KN, Lanphear BP. May 2014

Regulatory Forum Opinion Piece: New Testing Paradigms for Reproductive and Developmental Toxicity — The NTP Modified One Generation Study and OECD 443 [Abstract Regulatory Forum Opinion Piece: New Testing Paradigms for Reproductive and Developmental Toxicity — The NTP Modified One Generation Study and OECD 443] [Synopsis Regulatory Forum Opinion Piece: New Testing Paradigms for Reproductive and Developmental Toxicity — The NTP Modified One Generation Study and OECD 443] Foster PM. May 2014

Retinoic Acid-related Orphan Receptor Gamma (RORgamma): A Novel Participant in the Diurnal Regulation of Hepatic Gluconeogenesis and Insulin Sensitivity [Abstract Retinoic Acid-related Orphan Receptor Gamma (RORgamma): A Novel Participant in the Diurnal Regulation of Hepatic Gluconeogenesis and Insulin Sensitivity] [Synopsis Retinoic Acid-related Orphan Receptor Gamma (RORgamma): A Novel Participant in the Diurnal Regulation of Hepatic Gluconeogenesis and Insulin Sensitivity] Takeda Y, Kang HS, Freudenberg J, DeGraff LM, Jothi R, Jetten AM. May 2014

Role of Polymerase Beta in Complementing Aprataxin Deficiency During Abasic-site Base Excision Repair [Abstract Role of Polymerase Beta in Complementing Aprataxin Deficiency During Abasic-site Base Excision Repair] [Synopsis Role of Polymerase Beta in Complementing Aprataxin Deficiency During Abasic-site Base Excision Repair] Caglayan M, Batra VK, Sassa A, Prasad R, Wilson SH. May 2014

Single-molecule Analysis Reveals Human UV-damaged DNA-binding Protein (UV-DDB) Dimerizes on DNA Via Multiple Kinetic Intermediates [Abstract Single-molecule Analysis Reveals Human UV-damaged DNA-binding Protein (UV-DDB) Dimerizes on DNA Via Multiple Kinetic Intermediates] [Synopsis Single-molecule Analysis Reveals Human UV-damaged DNA-binding Protein (UV-DDB) Dimerizes on DNA Via Multiple Kinetic Intermediates] Ghodke H, Wang H, Hsieh CL, Woldemeskel S, Watkins SC, Rapic-Otrin V, Van Houten B. May 2014

CpG Sites Associated with Cigarette Smoking: Analysis of Epigenome-Wide Data from the Sister Study [Abstract CpG Sites Associated with Cigarette Smoking: Analysis of Epigenome-Wide Data from the Sister Study] [Synopsis CpG Sites Associated with Cigarette Smoking: Analysis of Epigenome-Wide Data from the Sister Study] Harlid S, Xu Z, Panduri V, Sandler DP, Taylor JA. April 2014

DNA Polymerase V Activity is Autoregulated by a Novel Intrinsic DNA-dependent ATPase [Abstract DNA Polymerase V Activity is Autoregulated by a Novel Intrinsic DNA-dependent ATPase] [Synopsis DNA Polymerase V Activity is Autoregulated by a Novel Intrinsic DNA-dependent ATPase] Erdem AL, Jaszczur M, Bertram JG, Woodgate R, Cox MM, Goodman MF. April 2014

Grp1-associated Scaffold Protein Regulates Skin Homeostasis After Ultraviolet Irradiation [Abstract Grp1-associated Scaffold Protein Regulates Skin Homeostasis After Ultraviolet Irradiation] [Synopsis Grp1-associated Scaffold Protein Regulates Skin Homeostasis After Ultraviolet Irradiation] Venkataraman A, Coleman DJ, Nevrivy DJ, Long T, Kioussi C, Indra AK, Leid M. April 2014

Integrative Framework for Identification of Key Cell Identity Genes Uncovers Determinants of ES Cell Identity and Homeostasis [Abstract Integrative Framework for Identification of Key Cell Identity Genes Uncovers Determinants of ES Cell Identity and Homeostasis] [Synopsis Integrative Framework for Identification of Key Cell Identity Genes Uncovers Determinants of ES Cell Identity and Homeostasis] Cinghu S, Yellaboina S, Freudenberg JM, Ghosh S, Zheng X, Oldfield AJ, Lackford BL, Zaykin DV, Hu G, Jothi R. April 2014

p53 and NF-kappaB Coregulate Proinflammatory Gene Responses in Human Macrophages [Abstract p53 and NF-kappaB Coregulate Proinflammatory Gene Responses in Human Macrophages] [Synopsis p53 and NF-kappaB Coregulate Proinflammatory Gene Responses in Human Macrophages] [Story p53 and NF-kappaB Coregulate Proinflammatory Gene Responses in Human Macrophages] Lowe JM, Menendez D, Bushel PR, Shatz M, Kirk EL, Troester MA, Garantziotis S, Fessler MB, Resnick MA. April 2014

Phthalate Exposure and Pubertal Development in a Longitudinal Study of U.S. Girls [Abstract Phthalate Exposure and Pubertal Development in a Longitudinal Study of U.S. Girls] [Synopsis Phthalate Exposure and Pubertal Development in a Longitudinal Study of U.S. Girls] Wolff MS, Teitelbaum SL, McGovern K, Windham GC, Pinney SM, Galvez M, Calafat AM, Kushi LH, Biro FM, on behalf of the Breast Cancer and Environment Research Program. April 2014

Prenatal SSRI Use and Offspring with Autism Spectrum Disorder or Developmental Delay [Abstract Prenatal SSRI Use and Offspring with Autism Spectrum Disorder or Developmental Delay] [Synopsis Prenatal SSRI Use and Offspring with Autism Spectrum Disorder or Developmental Delay] Harrington RA, Lee LC, Crum RM, Zimmerman AW, Hertz-Picciotto I. April 2014

Preterm Birth and Random Plasma Insulin Levels at Birth and in Early Childhood [Abstract Preterm Birth and Random Plasma Insulin Levels at Birth and in Early Childhood] [Synopsis Preterm Birth and Random Plasma Insulin Levels at Birth and in Early Childhood] Wang G, Divall S, Radovick S, Paige D, Ning Y, Chen Z, Ji Y, Hong X, Walker SO, Caruso D, Pearson C, Wang MC, Zuckerman B, Cheng TL, Wang X. April 2014

Prevalence of Allergic Sensitization in the United States: Results from the National Health and Nutrition Examination Survey (NHANES) 2005-2006 [Abstract Prevalence of Allergic Sensitization in the United States: Results from the National Health and Nutrition Examination Survey (NHANES) 2005-2006] [Synopsis Prevalence of Allergic Sensitization in the United States: Results from the National Health and Nutrition Examination Survey (NHANES) 2005-2006] Salo PM, Arbes SJ Jr, Jaramillo R, Calatroni A, Weir CH, Sever ML, Hoppin JA, Rose KM, Liu AH, Gergen PJ, Mitchell HE, Zeldin DC. April 2014

Reduction of the Body Burden of PCBs and DDE by Dietary Intervention in a Randomized Trial [Abstract Reduction of the Body Burden of PCBs and DDE by Dietary Intervention in a Randomized Trial] [Synopsis Reduction of the Body Burden of PCBs and DDE by Dietary Intervention in a Randomized Trial] Jandacek RJ, Heubi JE, Buckley DD, Khoury JC, Turner WE, Sjodin A, Olson JR, Shelton C, Helms K, Bailey TD, Carter S, Tso P, Pavuk M. April 2014

Seasonal Ambient Air Pollution Correlates Strongly with Spontaneous Abortion in Mongolia [Abstract Seasonal Ambient Air Pollution Correlates Strongly with Spontaneous Abortion in Mongolia] [Synopsis Seasonal Ambient Air Pollution Correlates Strongly with Spontaneous Abortion in Mongolia] Enkhmaa D, Warburton N, Javzandulam B, Uyanga J, Khishigsuren Y, Lodoysamba S, Enkhtur S, Warburton D. April 2014

Serum MicroRNA Expression as an Early Marker for Breast Cancer Risk in Prospectively Collected Samples from the Sister Study Cohort [Abstract Serum MicroRNA Expression as an Early Marker for Breast Cancer Risk in Prospectively Collected Samples from the Sister Study Cohort] [Synopsis Serum MicroRNA Expression as an Early Marker for Breast Cancer Risk in Prospectively Collected Samples from the Sister Study Cohort] Godfrey AC, Xu Z, Weinberg CR, Getts RC, Wade PA, DeRoo LA, Sandler DP, Taylor JA. April 2014

Temporal Trends in Phthalate Exposures: Findings from the National Health and Nutrition Examination Survey, 2001-2010 [Abstract Temporal Trends in Phthalate Exposures: Findings from the National Health and Nutrition Examination Survey, 2001-2010] [Synopsis Temporal Trends in Phthalate Exposures: Findings from the National Health and Nutrition Examination Survey, 2001-2010] Zota AR, Calafat AM, Woodruff TJ. April 2014

APOepsilon4 Is Associated With Enhanced In Vivo Innate Immune Responses in Human Subjects [Abstract APOepsilon4 Is Associated With Enhanced In Vivo Innate Immune Responses in Human Subjects] [Synopsis APOepsilon4 Is Associated With Enhanced In Vivo Innate Immune Responses in Human Subjects] Gale SC, Gao L, Mikacenic C, Coyle SM, Rafaels N, Murray Dudenkov T, Madenspacher JH, Draper DW, Ge W, Aloor JJ, Azzam KM, Lai L, Blackshear PJ, Calvano SE, Barnes KC, Lowry SF, Corbett S, Wurfel MM, Fessler MB. March 2014

Asymmetry in Family History Implicates Nonstandard Genetic Mechanisms: Application to the Genetics of Breast Cancer [Abstract Asymmetry in Family History Implicates Nonstandard Genetic Mechanisms: Application to the Genetics of Breast Cancer] [Synopsis Asymmetry in Family History Implicates Nonstandard Genetic Mechanisms: Application to the Genetics of Breast Cancer] O’Connell SG, Kincl LD, Anderson KA. March 2014

Bisphenol A Promotes Human Prostate Stem-Progenitor Cell Self-Renewal and Increases In Vivo Carcinogenesis in Human Prostate Epithelium [Abstract Bisphenol A Promotes Human Prostate Stem-Progenitor Cell Self-Renewal and Increases In Vivo Carcinogenesis in Human Prostate Epithelium] [Synopsis Bisphenol A Promotes Human Prostate Stem-Progenitor Cell Self-Renewal and Increases In Vivo Carcinogenesis in Human Prostate Epithelium] Prins GS, Hu WY, Shi GB, Hu DP, Majumdar S, Li G, Huang K, Nelles JL, Ho SM, Walker CL, Kajdacsy-Balla A, van Breemen RB. March 2014

Elevated Serum Pesticide Levels and Risk for Alzheimer Disease [Abstract Elevated Serum Pesticide Levels and Risk for Alzheimer Disease] Richardson JR, Roy A, Shalat SL, von Stein RT, Hossain MM, Buckley B, Gearing M, Levey AI, German DC. March 2014

Exposure To Bisphenol A Correlates With Early-Onset Prostate Cancer and Promotes Centrosome Amplification and Anchorage-Independent Growth In Vitro [Abstract Exposure To Bisphenol A Correlates With Early-Onset Prostate Cancer and Promotes Centrosome Amplification and Anchorage-Independent Growth In Vitro] [Synopsis Exposure To Bisphenol A Correlates With Early-Onset Prostate Cancer and Promotes Centrosome Amplification and Anchorage-Independent Growth In Vitro] Tarapore P, Ying J, Ouyang B, Burke B, Bracken B, Ho SM. March 2014

Silicone Wristbands As Personal Passive Samplers [Abstract Silicone Wristbands As Personal Passive Samplers] [Synopsis Silicone Wristbands As Personal Passive Samplers] O’Connell SG, Kincl LD, Anderson KA. March 2014

Sustained Active Site Rigidity During Synthesis by Human DNA Polymerase Mu [Abstract Sustained Active Site Rigidity During Synthesis by Human DNA Polymerase Mu] Moon AF, Pryor JM, Ramsden DA, Kunkel TA, Bebenek K, Pedersen LC. March 2014

Temporal Trends in Phtalate Exposures: Findings From the National Health and Nutrition Examination Survey [Abstract Temporal Trends in Phtalate Exposures: Findings From the National Health and Nutrition Examination Survey] [Synopsis Temporal Trends in Phtalate Exposures: Findings From the National Health and Nutrition Examination Survey] Zota AR, Calafat AM, Woodruff TJ. March 2014

Toxicity and Biodistribution of the Serotype 2 Recombinant Adeno-Associated Viral Vector, Encoding Aquaporin-1, After Retroductal Delivery to a Single Mouse Parotid Gland [Abstract Toxicity and Biodistribution of the Serotype 2 Recombinant Adeno-Associated Viral Vector, Encoding Aquaporin-1, After Retroductal Delivery to a Single Mouse Parotid Gland] [Synopsis Toxicity and Biodistribution of the Serotype 2 Recombinant Adeno-Associated Viral Vector, Encoding Aquaporin-1, After Retroductal Delivery to a Single Mouse Parotid Gland] Momot D, Zheng C, Yin H, Elbekai RH, Vallant M, Chiorini JA. March 2014

Aprataxin Resolves Adenylated RNA-DNA Junctions To Maintain Genome Integrity [Abstract Aprataxin Resolves Adenylated RNA-DNA Junctions To Maintain Genome Integrity] [Synopsis Aprataxin Resolves Adenylated RNA-DNA Junctions To Maintain Genome Integrity] Tumbale P, Williams JS, Schellenberg MJ, Kunkel TA, Williams RS. February 2014

Benzimidazoisoquinolines: A New Class Of Rapidly Metabolized Aryl Hydrocarbon Receptor (AhR) Ligands That Induce AhR-Dependent Tregs and Prevent Murin Graft-Versus-Host Disease [Abstract Benzimidazoisoquinolines: A New Class Of Rapidly Metabolized Aryl Hydrocarbon Receptor (AhR) Ligands That Induce AhR-Dependent Tregs and Prevent Murin Graft-Versus-Host Disease] [Synopsis Benzimidazoisoquinolines: A New Class Of Rapidly Metabolized Aryl Hydrocarbon Receptor (AhR) Ligands That Induce AhR-Dependent Tregs and Prevent Murin Graft-Versus-Host Disease] Puni S, Kopparapu P, Jang HS, Phillips JL, Pennington J, Rohlman D, O’Donnell E, Iversen PL, Kolluri SK, Kerkvliet NI. February 2014

Genome-Wide Association Mapping of Acute Lung Injury in Neonatal Inbred Mice [Abstract Genome-Wide Association Mapping of Acute Lung Injury in Neonatal Inbred Mice] [Synopsis Genome-Wide Association Mapping of Acute Lung Injury in Neonatal Inbred Mice] Nichols JL, Gladwell W, Verhein KC, Cho HY, Wess J, Suzuki O, Wiltshire T, Kleeberger SR. February 2014

A Genetic Model of Differential Susceptibility To Human Respiratory Syncytial Virus (RSV) Infection [Abstract A Genetic Model of Differential Susceptibility To Human Respiratory Syncytial Virus (RSV) Infection] [Synopsis A Genetic Model of Differential Susceptibility To Human Respiratory Syncytial Virus (RSV) Infection] Ciencewicki JM, Wang X, Marzec J, Serra ME, Bell DA, Polack FP, Kleeberger SR. January 2014

A Simulation Model of Building Intervention Impacts On Indoor Environmental Quality, Pediatric Asthma, and Costs [Abstract A Simulation Model of Building Intervention Impacts On Indoor Environmental Quality, Pediatric Asthma, and Costs] [Synopsis A Simulation Model of Building Intervention Impacts On Indoor Environmental Quality, Pediatric Asthma, and Costs] Fabian MP, Adamkiewicz G, Stout NK, Sandel M, Levy JI. January 2014

Mutational and Structural Analysis of the Tandem Zinc Finger Domain of Tristetraprolin [Abstract Mutational and Structural Analysis of the Tandem Zinc Finger Domain of Tristetraprolin] [Synopsis Mutational and Structural Analysis of the Tandem Zinc Finger Domain of Tristetraprolin] Lai WS, Perera L, Hicks SN, Blackshear PJ. January 2014

Mutation of POLB Causes Lupus in Mice [Abstract Mutation of POLB Causes Lupus in Mice] [Synopsis Mutation of POLB Causes Lupus in Mice] Senejani AG, Liu Y, Kidane D, Maher SE, Zeiss CJ, Park HJ, Kashgarian M, McNiff JM, Zelterman D, Bothwell AL, Sweasy JB. January 2014

Novel Methylation Biomarker Panel for the Early Detection of Pancreatic Cancer [Abstract Novel Methylation Biomarker Panel for the Early Detection of Pancreatic Cancer] [Synopsis Novel Methylation Biomarker Panel for the Early Detection of Pancreatic Cancer] Yi JM, Guzzetta AA, Bailey VJ, Downing SR, Van Neste L, Chiappinelli KB, Keeley BP, Stark A, Herrera A, Wolfgang C, Pappou EP, Iacobuzio-Donahue CA, Goggins MG, Herman JG, Wang TH, Baylin SB, Ahuja N. January 2014

Onset of Breast Development in a Longitudinal Cohort [Abstract Onset of Breast Development in a Longitudinal Cohort] [Synopsis Onset of Breast Development in a Longitudinal Cohort] Biro FM, Greenspan LC, Galvez MP, Pinney SM, Teitelbaum S, Windham GC, Deardorff J, Herrick RL, Succop PA, Hiatt RA, Kushi LH, Wolff MS. January 2014

Presynaptic alpha7 Nicotinic Acetylcholine Receptors Enhance Hippocampal Mossy Fiber Glutamatergic Transmission Via PKA Activation [Abstract Presynaptic alpha7 Nicotinic Acetylcholine Receptors Enhance Hippocampal Mossy Fiber Glutamatergic Transmission Via PKA Activation] [Synopsis Presynaptic alpha7 Nicotinic Acetylcholine Receptors Enhance Hippocampal Mossy Fiber Glutamatergic Transmission Via PKA Activation] Cheng Q, Yakel JL. January 2014

Stable Pausing by RNA Polymerase II Provides an Opportunity to Target and Integrate Regulatory Signals [Abstract Stable Pausing by RNA Polymerase II Provides an Opportunity to Target and Integrate Regulatory Signals] [Synopsis Stable Pausing by RNA Polymerase II Provides an Opportunity to Target and Integrate Regulatory Signals] Henriques T, Gilchrist DA, Nechaev S, Bern M, Muse GW, Burkholder A, Fargo DC, Adelman K. January 2014

Analysis of the SWI/SNF Chromatin-Remodeling Complex During Early Heart Development and BAF250a Repression Cardiac Gene Transcription During P19 Cell Differentiation [Abstract Analysis of the SWI/SNF Chromatin-Remodeling Complex During Early Heart Development and BAF250a Repression Cardiac Gene Transcription During P19 Cell Differentiation] [Synopsis Analysis of the SWI/SNF Chromatin-Remodeling Complex During Early Heart Development and BAF250a Repression Cardiac Gene Transcription During P19 Cell Differentiation] Singh AP, Archer TK. December 2013

Ancestral Dichlorodiphenyltrichloroethane (DDT) Exposure Promotes Epigenetic Transgenerational Inheritance of Obesity [Abstract Ancestral Dichlorodiphenyltrichloroethane (DDT) Exposure Promotes Epigenetic Transgenerational Inheritance of Obesity] [Synopsis Ancestral Dichlorodiphenyltrichloroethane (DDT) Exposure Promotes Epigenetic Transgenerational Inheritance of Obesity] Skinner MK, Manikkam M, Tracey R, Guerrero-Bosagna C, Haque M, Nilsson EE. December 2013

A Polymorphic p53 Response Element in KIT Ligand Influences Cancer Risk and Has Undergone Natural Selection [Abstract A Polymorphic p53 Response Element in KIT Ligand Influences Cancer Risk and Has Undergone Natural Selection] [Synopsis A Polymorphic p53 Response Element in KIT Ligand Influences Cancer Risk and Has Undergone Natural Selection] [Story A Polymorphic p53 Response Element in KIT Ligand Influences Cancer Risk and Has Undergone Natural Selection] Zeron-Medina J, Wang X, Repapi E, Campbell MR, Su D, Castro-Giner F, Davies B, Peterse EF, Sacilotto N, Walker GJ, Terzian T, Tomlinson IP, Box NF, Meinshausen N, De Val S, Bell DA, Bond GL. December 2013

Diethylstilbestrol (DES)-Stimulated Hormonal Toxicity is Mediated by ERalpha Alteration of Target Gene Methylation Patterns and Epigenetic Modifiers (DNMT3A, MBD2, and HDAC2) in the Mouse Seminal Vesicle [Abstract Diethylstilbestrol (DES)-Stimulated Hormonal Toxicity is Mediated by ERalpha Alteration of Target Gene Methylation Patterns and Epigenetic Modifiers (DNMT3A, MBD2, and HDAC2) in the Mouse Seminal Vesicle] [Synopsis Diethylstilbestrol (DES)-Stimulated Hormonal Toxicity is Mediated by ERalpha Alteration of Target Gene Methylation Patterns and Epigenetic Modifiers (DNMT3A, MBD2, and HDAC2) in the Mouse Seminal Vesicle] Li Y, Hamilton KJ, Lai AY, Burns KA, Li L, Wade PA, Korach KS. December 2013

Digital Genomic Quantification of Tumor-Infiltrating Lymphocytes [Abstract Digital Genomic Quantification of Tumor-Infiltrating Lymphocytes] [Synopsis Digital Genomic Quantification of Tumor-Infiltrating Lymphocytes] Robins HS, Ericson NG, Guenthoer J, O’Briant KC, Tewari M, Drescher CW, Bielas JH. December 2013

Exonic Transcription Factor Binding Directs Codon Choice and Affects Protein Evolution [Abstract Exonic Transcription Factor Binding Directs Codon Choice and Affects Protein Evolution] [Synopsis Exonic Transcription Factor Binding Directs Codon Choice and Affects Protein Evolution] Stergachis AB, Haugen E, Shafer A, Fu W, Vernot B, Reynolds A, Raubitschek A, Ziegler S, LeProust EM, Akey JM, Stamatoyannopoulos JA. December 2013

HES1 is a Master Regulator of Glucocorticoid Receptor-Dependent Gene Expression [Abstract HES1 is a Master Regulator of Glucocorticoid Receptor-Dependent Gene Expression] [Synopsis HES1 is a Master Regulator of Glucocorticoid Receptor-Dependent Gene Expression] Revollo JR, Oakley RH, Lu NZ, Kadmiel M, Gandhavadi M, Cidlowski JA. December 2013

Intestine-Specific Deletion of SIRT1 in Mice Impairs DCoH2-HNF-1alpha-FXR Signaling and Alters Systemic Bile Acid Homeostasis [Abstract Intestine-Specific Deletion of SIRT1 in Mice Impairs DCoH2-HNF-1alpha-FXR Signaling and Alters Systemic Bile Acid Homeostasis] [Synopsis Intestine-Specific Deletion of SIRT1 in Mice Impairs DCoH2-HNF-1alpha-FXR Signaling and Alters Systemic Bile Acid Homeostasis] Kazgan N, Metukuri MR, Purushotham A, Lu J, Rao A, Lee S, Pratt-Hyatt M, Lickteig A, Csanaky IL, Zhao Y, Dawson PA, Li X. December 2013

Isogenic Human iPSC Parkinson’s Model Shows Nitrosative Stress-Induced Dysfunction in MEF2-PGC1alpha Transcription [Abstract Isogenic Human iPSC Parkinson’s Model Shows Nitrosative Stress-Induced Dysfunction in MEF2-PGC1alpha Transcription] [Synopsis Isogenic Human iPSC Parkinson’s Model Shows Nitrosative Stress-Induced Dysfunction in MEF2-PGC1alpha Transcription] Ryan SD, Dolatabadi N, Chan SF, Zhang X, Akhtar MW, Parker J, Soldner F, Sunico CR, Nagar S, Talantova M, Lee B, Lopez K, Nutter A, Shan B, Molokanova E, Zhang Y, Han X, Nakamura T, Masliah E, Yates JR 3rd, Nakanishi N, Andreyev AY, Okamoto S, Jaenisch R, Ambasudhan R, Lipton SA. December 2013

Maternal Engineered Nanomaterial Exposure and Fetal Microvascular Function: Does the Barker Hypothesis Apply? [Abstract Maternal Engineered Nanomaterial Exposure and Fetal Microvascular Function: Does the Barker Hypothesis Apply?] [Synopsis Maternal Engineered Nanomaterial Exposure and Fetal Microvascular Function: Does the Barker Hypothesis Apply?] Stapleton PA, Minarchick VC, Yi J, Engels K, McBride CR, Nurkiewicz TR. December 2013

MBD3 Localizes at Promoters, Gene Bodies, and Enhancers of Active Genes [Abstract MBD3 Localizes at Promoters, Gene Bodies, and Enhancers of Active Genes] [Synopsis MBD3 Localizes at Promoters, Gene Bodies, and Enhancers of Active Genes] Shimbo T, Du Y, Grimm SA, Dhasarathy A, Mav D, Shah RR, Shi H, Wade PA. December 2013

Structure-function Analysis of Ribonucleotide Bypass by B Family DNA Replicases [Abstract Structure-function Analysis of Ribonucleotide Bypass by B Family DNA Replicases] [Synopsis Structure-function Analysis of Ribonucleotide Bypass by B Family DNA Replicases] Clausen AR, Murray MS, Passer AR, Pedersen LC, Kunkel TA. December 2013

The THO Complex Regulates Pluripotency Gene mRNA Export and Controls Embryonic Stem Cell Self-Renewal and Somatic Cell Reprogramming [Abstract The THO Complex Regulates Pluripotency Gene mRNA Export and Controls Embryonic Stem Cell Self-Renewal and Somatic Cell Reprogramming] [Synopsis The THO Complex Regulates Pluripotency Gene mRNA Export and Controls Embryonic Stem Cell Self-Renewal and Somatic Cell Reprogramming] Wang L, Miao YL, Zheng X, Lackford B, Zhou B, Han L, Yao C, Ward JM, Burkholder A, Lipchina I, Fargo DC, Hochedlinger K, Shi Y, Williams CJ, Hu G. December 2013

A CTD-Pfizer Collaboration: Manual Curation of 88,000 Scientific Articles Text Mined for Drug-Disease and Drug-Phenotype Interactions [Abstract A CTD-Pfizer Collaboration: Manual Curation of 88,000 Scientific Articles Text Mined for Drug-Disease and Drug-Phenotype Interactions] [Synopsis A CTD-Pfizer Collaboration: Manual Curation of 88,000 Scientific Articles Text Mined for Drug-Disease and Drug-Phenotype Interactions] Davis AP, Wiegers TC, Roberts PM, King BL, Lay JM, Lennon-Hopkins K, Sciaky D, Johnson R, Keating H, Greene N, Hernandez R, McConnell KJ, Enayetallah AE, Mattingly CJ. November 2013

A High-Resolution Map of the Three-Dimensional Chromatin Interactome in Human Cells [Abstract A High-Resolution Map of the Three-Dimensional Chromatin Interactome in Human Cells] [Synopsis A High-Resolution Map of the Three-Dimensional Chromatin Interactome in Human Cells] Jin F, Li Y, Dixon JR, Selvaraj S, Ye Z, Lee AY, Yen CA, Schmitt AD, Espinoza CA, Ren B. November 2013

Environmental Phthalate Exposure and Preterm Birth [Abstract Environmental Phthalate Exposure and Preterm Birth] [Synopsis Environmental Phthalate Exposure and Preterm Birth] Ferguson KK, McElrath TF, Meeker JD. November 2013

Fungal-Derived Semiochemical 1-octen-3-ol Disrupts Dopamine Packaging and Causes Neurodegeneration [Abstract Fungal-Derived Semiochemical 1-octen-3-ol Disrupts Dopamine Packaging and Causes Neurodegeneration] [Synopsis Fungal-Derived Semiochemical 1-octen-3-ol Disrupts Dopamine Packaging and Causes Neurodegeneration] Inamdar AA, Hossain MM, Bernstein AI, Miller GW, Richardson JR, Bennett JW. November 2013

Global DNA Methylation and One-Carbon Metabolism Gene Polymorphisms and the Risk of Breast Cancer in the Sister Study [Abstract Global DNA Methylation and One-Carbon Metabolism Gene Polymorphisms and the Risk of Breast Cancer in the Sister Study] [Synopsis Global DNA Methylation and One-Carbon Metabolism Gene Polymorphisms and the Risk of Breast Cancer in the Sister Study] DeRoo LA, Bolick SC, Xu Z, Umbach DM, Shore D, Weinberg CR, Sandler DP, Taylor JA. November 2013

Hypermutability and Error Catastrophe Due to Defects in Ribonucleotide Reductase [Abstract Hypermutability and Error Catastrophe Due to Defects in Ribonucleotide Reductase] [Synopsis Hypermutability and Error Catastrophe Due to Defects in Ribonucleotide Reductase] Ahluwalia D, Schaaper RM. November 2013

Prenatal Exposure To Air Pollution, Maternal Psychological Distress, and Child Behavior [Abstract Prenatal Exposure To Air Pollution, Maternal Psychological Distress, and Child Behavior] [Synopsis Prenatal Exposure To Air Pollution, Maternal Psychological Distress, and Child Behavior] Perera FP, Wang S, Rauh V, Zhou H, Stigter L, Camann D, Jedrychowski W, Mroz E, Majewska R. November 2013

Amino Acid Substitution in the Active Site of DNA Polymerase Beta Explains the Energy Barrier of the Nucleotidyl Transfer Reaction [Abstract Amino Acid Substitution in the Active Site of DNA Polymerase Beta Explains the Energy Barrier of the Nucleotidyl Transfer Reaction] [Synopsis Amino Acid Substitution in the Active Site of DNA Polymerase Beta Explains the Energy Barrier of the Nucleotidyl Transfer Reaction] Batra VK, Perera L, Lin P, Shock DD, Beard WA, Pedersen LC, Pedersen LG, Wilson SH. October 2013

Bisphenol A and Chronic Disease Risk Factors in US Children [Abstract Bisphenol A and Chronic Disease Risk Factors in US Children] [Synopsis Bisphenol A and Chronic Disease Risk Factors in US Children] Eng DS, Lee JM, Gebremariam A, Meeker JD, Peterson K, Padmanabhan V. October 2013

Cardiolipin Externalization to the Outer Mitochondrial Membrane Acts As An Elimination Signal for Mitophagy in Neuronal Cells [Abstract Cardiolipin Externalization to the Outer Mitochondrial Membrane Acts As An Elimination Signal for Mitophagy in Neuronal Cells] [Synopsis Cardiolipin Externalization to the Outer Mitochondrial Membrane Acts As An Elimination Signal for Mitophagy in Neuronal Cells] Chu CT, Ji J, Dagda RK, Jiang JF, Tyurina YY, Kapralov AA, Tyurin VA, Yanamala N, Shrivastava IH, Mohammadyani D, Qiang Wang KZ, Zhu J, Klein-Seetharaman J, Balasubramanian K, Amoscato AA, Borisenko G, Huang Z, Gudon AM, Cheikhi A, Steer EK, Wang R, Baty C, Watkins S, Bahar I, Bayir H, Kagan VE. October 2013

Charting a Dynamic DNA Methylation Landscape of the Human Genome [Abstract Charting a Dynamic DNA Methylation Landscape of the Human Genome] [Synopsis Charting a Dynamic DNA Methylation Landscape of the Human Genome] Ziller MJ, Gu H, Müller F, Donaghey J, Tsai LT, Kohlbacher O, De Jager PL, Rosen ED, Bennett DA, Bernstein BE, Gnirke A, Meissner A. October 2013

DNA Methylation Profiling in Human B Cells Reveals Immune Regulatory Elements and Epigenetic Plasticity at Alu Elements During B-cell Activation [Abstract DNA Methylation Profiling in Human B Cells Reveals Immune Regulatory Elements and Epigenetic Plasticity at Alu Elements During B-cell Activation] [Synopsis DNA Methylation Profiling in Human B Cells Reveals Immune Regulatory Elements and Epigenetic Plasticity at Alu Elements During B-cell Activation] Lai AY, Mav D, Shah R, Grimm SA, Phadke D, Hatzi K, Melnick A, Geigerman C, Sobol SE, Jaye DL, Wade PA. October 2013

Epoxyeicosanoids Promote Organ and Tissue Regeneration [Abstract Epoxyeicosanoids Promote Organ and Tissue Regeneration] [Synopsis Epoxyeicosanoids Promote Organ and Tissue Regeneration] Panigrahy D, Kalish BT, Huang S, Bielenberg DR, Le HD, Yang J, Edin ML, Lee CR, Benny O, Mudge DK, Butterfield CE, Mammoto A, Mammoto T, Inceoglu B, Jenkins RL, Simpson MA, Akino T, Lih FB, Tomer KB, Ingber DE, Hammock BD, Falck JR, Manthati VL, Kaipainen A, D'Amore PA, Puder M, Zeldin DC, Kieran MW. October 2013

Essential Role of Stress Hormone Signaling in Cardiomyocytes for the Prevention of Heart Disease [Abstract Essential Role of Stress Hormone Signaling in Cardiomyocytes for the Prevention of Heart Disease] [Synopsis Essential Role of Stress Hormone Signaling in Cardiomyocytes for the Prevention of Heart Disease] Oakley RH, Ren R, Cruz-Topete D, Bird GS, Myers PH, Boyle MC, Schneider MD, Willis MS, Cidlowski JA. October 2013

Genome-wide Association Study of Dermatomyositis Reveals Genetic Overlap with Other Autoimmune Disorders [Abstract Genome-wide Association Study of Dermatomyositis Reveals Genetic Overlap with Other Autoimmune Disorders] [Synopsis Genome-wide Association Study of Dermatomyositis Reveals Genetic Overlap with Other Autoimmune Disorders] Miller FW, Cooper RG, Vencovsky J, Rider LG, Danko K, Wedderburn LR, Lundberg IE, Pachman LM, Reed AM, Ytterberg SR, Padyukov L, Selva-O’Callaghan A, Radstake T, Isenberg DA, Chinoy H, Ollier WE, O’Hanlon TP, Peng B, Lee A, Lamb JA, Chen W, Amos CI, Gregersen PK; Myositis Genetics Consortium. October 2013

Homologous Recombination Rescues ssDNA Gaps Generated by Nucleotide Excision Repair and Reduced Translesion DNA Synthesis in Yeast G2 Cells [Abstract Homologous Recombination Rescues ssDNA Gaps Generated by Nucleotide Excision Repair and Reduced Translesion DNA Synthesis in Yeast G2 Cells] [Synopsis Homologous Recombination Rescues ssDNA Gaps Generated by Nucleotide Excision Repair and Reduced Translesion DNA Synthesis in Yeast G2 Cells] Ma W, Westmoreland JW, Resnick MA. October 2013

Length of Human Pregnancy and Contributors to Its Natural Variation [Abstract Length of Human Pregnancy and Contributors to Its Natural Variation] [Synopsis Length of Human Pregnancy and Contributors to Its Natural Variation] Jukic AM, Baird DD, Weinberg CR, McConnaughey DR, Wilcox AJ. October 2013

Mimicking of Estradiol Binding by Flame Retardants and Their Metabolites: A Crystallographic Analysis [Abstract Mimicking of Estradiol Binding by Flame Retardants and Their Metabolites: A Crystallographic Analysis] Gosavi RA, Knudsen GA, Birnbaum LS, Pedersen LC. October 2013

Modulation of Distinct Asthmatic Phenotypes in Mice by Dose-Dependent Inhalation of Microbial Products [Abstract Modulation of Distinct Asthmatic Phenotypes in Mice by Dose-Dependent Inhalation of Microbial Products] [Synopsis Modulation of Distinct Asthmatic Phenotypes in Mice by Dose-Dependent Inhalation of Microbial Products] Whitehead GS, Thomas SY, Cook DN. October 2013

Mutational Signature of Aristolochic Acid Exposure as Revealed by Whole-exome Sequencing [Abstract Mutational Signature of Aristolochic Acid Exposure as Revealed by Whole-exome Sequencing] [Synopsis Mutational Signature of Aristolochic Acid Exposure as Revealed by Whole-exome Sequencing] Hoang ML, Chen CH, Sidorenko VS, He J, Dickman KG, Yun BH, Moriya M, Niknafs N, Douville C, Karchin R, Turesky RJ, Pu YS, Vogelstein B, Papadopoulos N, Grollman AP, Kinzler KW, Rosenquist TA. October 2013

Predictors and Consequences of Global DNA Methylation in Cord Blood and at Three Years [Abstract Predictors and Consequences of Global DNA Methylation in Cord Blood and at Three Years] [Synopsis Predictors and Consequences of Global DNA Methylation in Cord Blood and at Three Years] erbstman JB, Wang S, Perera FP, Lederman SA, Vishnevetsky J, Rundle AG, Hoepner LA, Qu L, Tang D. October 2013

Probiotic Milk Consumption in Pregnancy and Infancy and Subsequent Childhood Allergic Diseases [Abstract Probiotic Milk Consumption in Pregnancy and Infancy and Subsequent Childhood Allergic Diseases] [Synopsis Probiotic Milk Consumption in Pregnancy and Infancy and Subsequent Childhood Allergic Diseases] Bertelsen RJ, Brantsaeter AL, Magnus MC, Haugen M, Myhre R, Jacobsson B, Longnecker MP, Meltzer HM, London SJ. October 2013

Temporal Comparison of PBDEs, OH-PBDEs, PCBs, and OH-PCBs in the Serum of Second Trimester Pregnant Women Recruited from San Francisco General Hospital, California [Abstract Temporal Comparison of PBDEs, OH-PBDEs, PCBs, and OH-PCBs in the Serum of Second Trimester Pregnant Women Recruited from San Francisco General Hospital, California] [Synopsis Temporal Comparison of PBDEs, OH-PBDEs, PCBs, and OH-PCBs in the Serum of Second Trimester Pregnant Women Recruited from San Francisco General Hospital, California] Zota AR, Linderholm L, Park JS, Petreas M, Guo T, Privalsky ML, Zoeller RT, Woodruff TJ. October 2013

The Novel Structure of the Cockroach Allergen Bla g 1 Has Implications for Allergenicity and Exposure Assessment [Abstract The Novel Structure of the Cockroach Allergen Bla g 1 Has Implications for Allergenicity and Exposure Assessment] [Synopsis The Novel Structure of the Cockroach Allergen Bla g 1 Has Implications for Allergenicity and Exposure Assessment] Mueller GA, Pedersen LC, Lih FB, Glesner J, Moon AF, Chapman MD, Tomer KB, London RE, Pomes A. October 2013

Low Levels of Copper Disrupt Brain Amyloid-beta Homeostasis by Altering Its Production and Clearance [Abstract Low Levels of Copper Disrupt Brain Amyloid-beta Homeostasis by Altering Its Production and Clearance] [Synopsis Low Levels of Copper Disrupt Brain Amyloid-beta Homeostasis by Altering Its Production and Clearance] Singh I, Sagare AP, Coma M, Perlmutter D, Gelein R, Bell RD, Dean RJ, Zhong E, Parisi M, Ciszewski J, Kasper RT, Deane R. September 2013

Prenatal Nitrate Intake from Drinking Water and Selected Birth Defects in Offspring of Participants in the National Birth Defects Prevention Study [Abstract Prenatal Nitrate Intake from Drinking Water and Selected Birth Defects in Offspring of Participants in the National Birth Defects Prevention Study] [Synopsis Prenatal Nitrate Intake from Drinking Water and Selected Birth Defects in Offspring of Participants in the National Birth Defects Prevention Study] Brender JD, Weyer PJ, Romitti PA, Mohanty BP, Shinde MU, Vuong AM, Sharkey JR, Dwivedi D, Horel SA, Kantamneni J, Huber JC Jr, Zheng Q, Werler MM, Kelley KE, Griesenbeck JS, Zhan FB, Langlois PH, Suarez L, Canfield MA. September 2013

An APOBEC Cytidine Deaminase Mutagenesis Pattern is Widespread in Human Cancers [Abstract An APOBEC Cytidine Deaminase Mutagenesis Pattern is Widespread in Human Cancers] [Synopsis An APOBEC Cytidine Deaminase Mutagenesis Pattern is Widespread in Human Cancers] Roberts SA, Lawrence MS, Klimczak LJ, Grimm SA, Fargo D, Stojanov P, Kiezun A, Kryukov GV, Carter SL, Saksena G, Harris S, Shah RR, Resnick MA, Getz G, Gordenin DA. August 2013

Developmental Origins of Central Norepinephrine Neuron Diversity [Abstract Developmental Origins of Central Norepinephrine Neuron Diversity] [Synopsis Developmental Origins of Central Norepinephrine Neuron Diversity] Robertson SD, Plummer NW, de Marchena J, Jensen P. August 2013

Diverse Stresses Dramatically Alter Genome-Wide p53 Binding and Transactivation Landscape in Human Cancer Cells [Abstract Diverse Stresses Dramatically Alter Genome-Wide p53 Binding and Transactivation Landscape in Human Cancer Cells] [Synopsis Diverse Stresses Dramatically Alter Genome-Wide p53 Binding and Transactivation Landscape in Human Cancer Cells] Menendez D, Nguyen TA, Freudenberg JM, Mathew VJ, Anderson CW, Jothi R, Resnick MA. August 2013

Brief Report: Ultraviolet Radiation Exposure is Associated with Clinical and Autoantibody Phenotypes in Juvenile Myositis [Abstract Brief Report: Ultraviolet Radiation Exposure is Associated with Clinical and Autoantibody Phenotypes in Juvenile Myositis] [Synopsis Brief Report: Ultraviolet Radiation Exposure is Associated with Clinical and Autoantibody Phenotypes in Juvenile Myositis] Shah M, Targoff IN, Rice MM, Miller FW, Rider LG; Childhood Myositis Heterogeneity Collaborative Study Group. July 2013

Estrogen Receptor Alpha L543A, L544A Mutation Changes Antagonists to Agonists, Correlating with the Ligand Binding Domain Dimerization Associated with DNA Binding Activity [Abstract Estrogen Receptor Alpha L543A, L544A Mutation Changes Antagonists to Agonists, Correlating with the Ligand Binding Domain Dimerization Associated with DNA Binding Activity] [Synopsis Estrogen Receptor Alpha L543A, L544A Mutation Changes Antagonists to Agonists, Correlating with the Ligand Binding Domain Dimerization Associated with DNA Binding Activity] Arao Y, Hamilton KJ, Coons LA, Korach KS. July 2013

Graphene Microsheets Enter Cells Through Spontaneous Membrane Penetration At Edge Asperities and Corner Sites [Abstract Graphene Microsheets Enter Cells Through Spontaneous Membrane Penetration At Edge Asperities and Corner Sites] [Synopsis Graphene Microsheets Enter Cells Through Spontaneous Membrane Penetration At Edge Asperities and Corner Sites] Li Y, Yuan H, von dem Bussche A, Creighton M, Hurt RH, Kane AB, Gao H. July 2013

Hexavalent Chromium-Induced Alteration of Proteomic Landscape in Human Skin Fibroblast Cells [Abstract Hexavalent Chromium-Induced Alteration of Proteomic Landscape in Human Skin Fibroblast Cells] [Synopsis Hexavalent Chromium-Induced Alteration of Proteomic Landscape in Human Skin Fibroblast Cells] Guo L, Xiao Y, Wang Y. July 2013

Observing a DNA Polymerase Choose Right From Wrong [Abstract Observing a DNA Polymerase Choose Right From Wrong] [Synopsis Observing a DNA Polymerase Choose Right From Wrong] Freudenthal BD, Beard WA, Shock DD, Wilson SH. July 2013

Barium Distributions in Teeth Reveal Early-Life Dietary Transitions in Primates [Abstract Barium Distributions in Teeth Reveal Early-Life Dietary Transitions in Primates] [Synopsis Barium Distributions in Teeth Reveal Early-Life Dietary Transitions in Primates] Austin C, Smith TM, Bradman A, Hinde K, Joannes-Boyau R, Bishop D, Hare DJ, Doble P, Eskenazi B, Arora M. June 2013

Chronic Exposure of Mutant DISC1 Mice to Lead Produces Sex-Dependent Abnormalities Consistent with Schizophrenia and Related Mental Disorders: A Gene-Environment Interaction Study [Abstract Chronic Exposure of Mutant DISC1 Mice to Lead Produces Sex-Dependent Abnormalities Consistent with Schizophrenia and Related Mental Disorders: A Gene-Environment Interaction Study] [Synopsis Chronic Exposure of Mutant DISC1 Mice to Lead Produces Sex-Dependent Abnormalities Consistent with Schizophrenia and Related Mental Disorders: A Gene-Environment Interaction Study] Abazyan B, Dziedzic J, Hua K, Abazyan S, Yang C, Mori S, Pletnikov MV, Guilarte TR. June 2013

Economic Costs of Childhood Lead Exposure in Low- and Middle-Income Countries [Abstract Economic Costs of Childhood Lead Exposure in Low- and Middle-Income Countries] [Synopsis Economic Costs of Childhood Lead Exposure in Low- and Middle-Income Countries] Attina TM, Trasande L. June 2013

Impaired Transcriptional Response of the Murine Heart to Cigarette Smoke in the Setting of High Fat Diet and Obesity [Abstract Impaired Transcriptional Response of the Murine Heart to Cigarette Smoke in the Setting of High Fat Diet and Obesity] [Synopsis Impaired Transcriptional Response of the Murine Heart to Cigarette Smoke in the Setting of High Fat Diet and Obesity] Tilton SC, Karin NJ, Webb-Robertson BJ, Waters KM, Mikheev V, Lee KM, Corley RA, Pounds JG, Bigelow DJ. June 2013

Interlaboratory Evaluation of Rodent Pulmonary Responses to Engineered Nanomaterials: The NIEHS Nano GO Consortium [Abstract Interlaboratory Evaluation of Rodent Pulmonary Responses to Engineered Nanomaterials: The NIEHS Nano GO Consortium] [Synopsis Interlaboratory Evaluation of Rodent Pulmonary Responses to Engineered Nanomaterials: The NIEHS Nano GO Consortium] Bonner JC, Silva RM, Taylor AJ, Brown JM, Hilderbrand SC, Castranova V, Porter D, Elder A, Oberdorster G, Harkema JR, Bramble LA, Kavanagh TJ, Botta D, Nel A, Pinkerton KE. June 2013

Sex-Specific Epigenetic Disruption and Behavioral Changes Following Low-Dose In Utero Bisphenol A Exposure [Abstract Sex-Specific Epigenetic Disruption and Behavioral Changes Following Low-Dose In Utero Bisphenol A Exposure] [Synopsis Sex-Specific Epigenetic Disruption and Behavioral Changes Following Low-Dose In Utero Bisphenol A Exposure] Kundakovic M, Gudsnuk K, Franks B, Madrid J, Miller RL, Perera FP, Champagne FA. June 2013

The Bromodomain Protein Brd4 Insulates Chromatin from DNA Damage Signalling [Abstract The Bromodomain Protein Brd4 Insulates Chromatin from DNA Damage Signalling] [Synopsis The Bromodomain Protein Brd4 Insulates Chromatin from DNA Damage Signalling] Floyd SR, Pacold ME, Huang Q, Clarke SM, Lam FC, Cannell IG, Bryson BD, Rameseder J, Lee MJ, Blake EJ, Frydrych A, Ho R, Greenberger BA, Chen GC, Maffa A, Del Rosario AM, Root DE, Carpenter AE, Hahn WC, Sabatini DM, Chen CC, White FM, Bradner JE, Yaffe MB. June 2013

Epigenome-wide Association Study of Breast Cancer Using Prospectively Collected Sister Study Samples [Abstract Epigenome-wide Association Study of Breast Cancer Using Prospectively Collected Sister Study Samples] [Synopsis Epigenome-wide Association Study of Breast Cancer Using Prospectively Collected Sister Study Samples] Xu Z, Bolick SC, DeRoo LA, Weinberg CR, Sandler DP, Taylor JA. May 2013

Identification of Altered Metabolic Pathways in Plasma and CSF in Mild Cognitive Impairment and Alzheimer’s Disease Using Metabolomics [Abstract Identification of Altered Metabolic Pathways in Plasma and CSF in Mild Cognitive Impairment and Alzheimer’s Disease Using Metabolomics] [Synopsis Identification of Altered Metabolic Pathways in Plasma and CSF in Mild Cognitive Impairment and Alzheimer’s Disease Using Metabolomics] Trushina E, Dutta T, Persson XM, Mielke MM, Petersen RC. May 2013

Ligand-Induced Repression of the Glucocorticoid Receptor Gene Is Mediated by an NCoR1 Repression Complex Formed by Long-Range Chromatin Interactions with Intragenic Glucocorticoid Response Elements [Abstract Ligand-Induced Repression of the Glucocorticoid Receptor Gene Is Mediated by an NCoR1 Repression Complex Formed by Long-Range Chromatin Interactions with Intragenic Glucocorticoid Response Elements] [Synopsis Ligand-Induced Repression of the Glucocorticoid Receptor Gene Is Mediated by an NCoR1 Repression Complex Formed by Long-Range Chromatin Interactions with Intragenic Glucocorticoid Response Elements] Ramamoorthy S, Cidlowski JA. May 2013

Nicotine from Edible Solanaceae and Risk of Parkinson Disease [Abstract Nicotine from Edible Solanaceae and Risk of Parkinson Disease] [Synopsis Nicotine from Edible Solanaceae and Risk of Parkinson Disease] Nielsen SS, Franklin GM, Longstreth WT, Swanson PD, Checkoway H. May 2013

p53 Integrates Host Defense and Cell Fate During Bacterial Pneumonia [Abstract p53 Integrates Host Defense and Cell Fate During Bacterial Pneumonia] [Synopsis p53 Integrates Host Defense and Cell Fate During Bacterial Pneumonia] Madenspacher JH, Azzam KM, Gowdy KM, Malcolm KC, Nick JA, Dixon D, Aloor JJ, Draper DW, Guardiola JJ, Shatz M, Menendez D, Lowe J, Lu J, Bushel P, Li L, Merrick BA, Resnick MA, Fessler MB. May 2013

Phenobarbital Indirectly Activates the Constitutive Active Androstane Receptor (CAR) by Inhibition of Epidermal Growth Factor Receptor Signaling [Abstract Phenobarbital Indirectly Activates the Constitutive Active Androstane Receptor (CAR) by Inhibition of Epidermal Growth Factor Receptor Signaling] [Synopsis Phenobarbital Indirectly Activates the Constitutive Active Androstane Receptor (CAR) by Inhibition of Epidermal Growth Factor Receptor Signaling] Mutoh S, Sobhany M, Moore R, Perera L, Pedersen L, Sueyoshi T, Negishi M. May 2013

Prospero-Related Homeobox 1 (Prox1) Functions as a Novel Modulator of Retinoic Acid-Related Orphan Receptors Alpha- and Gamma-Mediated Transactivation [Abstract Prospero-Related Homeobox 1 (Prox1) Functions as a Novel Modulator of Retinoic Acid-Related Orphan Receptors Alpha- and Gamma-Mediated Transactivation] [Synopsis Prospero-Related Homeobox 1 (Prox1) Functions as a Novel Modulator of Retinoic Acid-Related Orphan Receptors Alpha- and Gamma-Mediated Transactivation] Takeda Y, Jetten AM. May 2013

Ribonucleotides Are Signals for Mismatch Repair of Leading-Strand Replication Errors [Abstract Ribonucleotides Are Signals for Mismatch Repair of Leading-Strand Replication Errors] [Synopsis Ribonucleotides Are Signals for Mismatch Repair of Leading-Strand Replication Errors] Lujan SA, Williams JS, Clausen AR, Clark AB, Kunkel TA. May 2013

The Association of Ambient Air Pollution and Traffic Exposures with Selected Congenital Anomalies in the San Joaquin Valley of California [Abstract The Association of Ambient Air Pollution and Traffic Exposures with Selected Congenital Anomalies in the San Joaquin Valley of California] [Synopsis The Association of Ambient Air Pollution and Traffic Exposures with Selected Congenital Anomalies in the San Joaquin Valley of California] Padula AM, Tager IB, Carmichael SL, Hammond SK, Lurmann F, Shaw GM. May 2013

Translesion Synthesis Past Acrolein-derived DNA Adducts by Human Mitochondrial DNA Polymerase Gamma [Abstract Translesion Synthesis Past Acrolein-derived DNA Adducts by Human Mitochondrial DNA Polymerase Gamma] [Synopsis Translesion Synthesis Past Acrolein-derived DNA Adducts by Human Mitochondrial DNA Polymerase Gamma] Kasiviswanathan R, Mink IG, Lloyd RS, Copeland WC. May 2013

Translesion Synthesis Past Acrolein-Derived DNA Adducts by Human Mitochondrial DNA Polymerase Gamma [Abstract Translesion Synthesis Past Acrolein-Derived DNA Adducts by Human Mitochondrial DNA Polymerase Gamma] [Synopsis Translesion Synthesis Past Acrolein-Derived DNA Adducts by Human Mitochondrial DNA Polymerase Gamma] Kasiviswanathan R, Minko IG, Lloyd RS, Copeland WC. May 2013

Beta-Arrestin-2 Deficiency Attenuates Abdominal Aortic Aneurysm Formation in Mice [Abstract Beta-Arrestin-2 Deficiency Attenuates Abdominal Aortic Aneurysm Formation in Mice] [Synopsis Beta-Arrestin-2 Deficiency Attenuates Abdominal Aortic Aneurysm Formation in Mice] Trivedi DB, Loftin CD, Clark J, Myers P, DeGraff LM, Cheng J, Zeldin DC, Langenbach R. April 2013

Cyclooxygenase-2 Inhibits T Helper Cell Type 9 Differentiation during Allergic Lung Inflammation via Down-regulation of IL-17RB [Abstract Cyclooxygenase-2 Inhibits T Helper Cell Type 9 Differentiation during Allergic Lung Inflammation via Down-regulation of IL-17RB] [Synopsis Cyclooxygenase-2 Inhibits T Helper Cell Type 9 Differentiation during Allergic Lung Inflammation via Down-regulation of IL-17RB] Li H, Edin ML, Bradbury JA, Graves JP, Degraff LM, Gruzdev A, Cheng J, Dackor RT, Wang PM, Bortner CD, Garantziotis S, Jetten AM, Zeldin DC. April 2013

Epoxy Metabolites of Docosahexaenoic Acid (DHA) Inhibit Angiogenesis, Tumor Growth, and Metastasis [Abstract Epoxy Metabolites of Docosahexaenoic Acid (DHA) Inhibit Angiogenesis, Tumor Growth, and Metastasis] [Synopsis Epoxy Metabolites of Docosahexaenoic Acid (DHA) Inhibit Angiogenesis, Tumor Growth, and Metastasis] Zhang D, Panigrahy D, Mahakian LM, Yang J, Liu JY, Stephen Lee KS, Wettersten HI, Ulu A, Hu X, Tam S, Hwang SH, Ingham ES, Kieran MW, Weiss RH, Ferrara KW, Hammock BD. April 2013

Global Increases in Both Common and Rare Copy Number Load Associated with Autism [Abstract Global Increases in Both Common and Rare Copy Number Load Associated with Autism] [Synopsis Global Increases in Both Common and Rare Copy Number Load Associated with Autism] Girirajan S, Johnson RL, Tassone F, Balciuniene J, Katiyar N, Fox K, Baker C, Srikanth A, Yeoh KH, Khoo SJ, Nauth TB, Hansen R, Ritchie M, Hertz-Picciotto I, Eichler EE, Pessah IN, Selleck SB. April 2013

Text Mining Effectively Scores and Ranks the Literature for Improving Chemical-Gene-Disease Curation at the Comparative Toxicogenomics Database [Abstract Text Mining Effectively Scores and Ranks the Literature for Improving Chemical-Gene-Disease Curation at the Comparative Toxicogenomics Database] [Synopsis Text Mining Effectively Scores and Ranks the Literature for Improving Chemical-Gene-Disease Curation at the Comparative Toxicogenomics Database] Davis AP, Wiegers TC, Johnson RJ, Lay JM, Lennon-Hopkins D, Saraceni-Richards C, Sciaky D, Murphy CG, Mattingly CJ. April 2013

The Natural Estrogenic Compound Diarylheptanoid (D3): In Vitro Mechanisms of Action and In Vivo Uterine Responses Via Estrogen Receptor Alpha [Abstract The Natural Estrogenic Compound Diarylheptanoid (D3): In Vitro Mechanisms of Action and In Vivo Uterine Responses Via Estrogen Receptor Alpha] [Synopsis The Natural Estrogenic Compound Diarylheptanoid (D3): In Vitro Mechanisms of Action and In Vivo Uterine Responses Via Estrogen Receptor Alpha] Winuthayanon W, Piyachaturawat P, Suksamrarn A, Burns KA, Arao Y, Hewitt SC, Pedersen LC, Korach KS. April 2013

Base Damage Within Single-strand DNA Underlies in Vivo Hypermutability Induced by a Ubiquitous Environmental Agent [Abstract Base Damage Within Single-strand DNA Underlies in Vivo Hypermutability Induced by a Ubiquitous Environmental Agent] [Synopsis Base Damage Within Single-strand DNA Underlies in Vivo Hypermutability Induced by a Ubiquitous Environmental Agent] Chan K, Sterling JF, Roberts SA, Bhagwat AS, Resnick MA, Gordenin DA. March 2013

Childhood Socioeconomic Factors and Perinatal Characteristics Influence Development of Rheumatoid Arthritis in Adulthood [Abstract Childhood Socioeconomic Factors and Perinatal Characteristics Influence Development of Rheumatoid Arthritis in Adulthood] [Synopsis Childhood Socioeconomic Factors and Perinatal Characteristics Influence Development of Rheumatoid Arthritis in Adulthood] Parks CG, D’Aloisio AA, DeRoo LA, Huiber K, Rider LG, Miller FW, Sandler DP. March 2013

Coincident Resection at Both Ends of Random, Gamma-Induced Double-Strand Breaks Requires MRX (MRN), Sae2 (Ctp1), and Mre11-Nuclease [Abstract Coincident Resection at Both Ends of Random, Gamma-Induced Double-Strand Breaks Requires MRX (MRN), Sae2 (Ctp1), and Mre11-Nuclease] [Synopsis Coincident Resection at Both Ends of Random, Gamma-Induced Double-Strand Breaks Requires MRX (MRN), Sae2 (Ctp1), and Mre11-Nuclease] Westmoreland JW, Resnick MA. March 2013

Elevated Maternal C-Reactive Protein and Autism in a National Birth Cohort [Abstract Elevated Maternal C-Reactive Protein and Autism in a National Birth Cohort] [Synopsis Elevated Maternal C-Reactive Protein and Autism in a National Birth Cohort] Brown AS, Sourander A, Hinkka-Yli-Salomäki S, McKeague IW, Sundvall J, Surcel HM. March 2013

Exposure to the Polybrominated Diphenyl Ether Mixture DE-71 Damages the Nigrostriatal Dopamine System: Role of Dopamine Handling in Neurotoxicity [Abstract Exposure to the Polybrominated Diphenyl Ether Mixture DE-71 Damages the Nigrostriatal Dopamine System: Role of Dopamine Handling in Neurotoxicity] [Synopsis Exposure to the Polybrominated Diphenyl Ether Mixture DE-71 Damages the Nigrostriatal Dopamine System: Role of Dopamine Handling in Neurotoxicity] Bradner JM, Suragh TA, Wilson WW, Lazo CR, Stout KA, Kim HM, Wang MZ, Walker DI, Pennell KD, Richardson JR, Miller GW, Caudle WM. March 2013

Polg2 Is Essential for Mammalian Embryogenesis and Is Required for mtDNA Maintenance [Abstract Polg2 Is Essential for Mammalian Embryogenesis and Is Required for mtDNA Maintenance] [Synopsis Polg2 Is Essential for Mammalian Embryogenesis and Is Required for mtDNA Maintenance] Humble MM, Young MJ, Foley JF, Pandiri AR, Travlos GS, Copeland WC. March 2013

Potential sources of bisphenol A in the neonatal intensive care unit [Abstract Potential sources of bisphenol A in the neonatal intensive care unit] [Synopsis Potential sources of bisphenol A in the neonatal intensive care unit] Duty SM, Mendonca K, Hauser R, Calafat AM, Ye X, Meeker JD, Ackerman R, Cullinane J, Faller J, Ringer S. March 2013

Prenatal and Infant Exposures and Age at Menarche [Abstract Prenatal and Infant Exposures and Age at Menarche] [Synopsis Prenatal and Infant Exposures and Age at Menarche] D’Aloisio AA, DeRoo LA, Baird DD, Weinberg CR, Sandler DP. March 2013

Prenatal Exposure to the Pesticide DDT and Hypertension Diagnosed in Women Before Age 50: A Longitudinal Birth Cohort Study [Abstract Prenatal Exposure to the Pesticide DDT and Hypertension Diagnosed in Women Before Age 50: A Longitudinal Birth Cohort Study] [Synopsis Prenatal Exposure to the Pesticide DDT and Hypertension Diagnosed in Women Before Age 50: A Longitudinal Birth Cohort Study] La Merrill M, Cirillo PM, Terry MB, Krigbaum NY, Flom JD, Cohn BA. March 2013

Promoting Integrated Approaches to Reducing Health Inequities Among Low-Income Workers: Applying a Social Ecological Framework [Abstract Promoting Integrated Approaches to Reducing Health Inequities Among Low-Income Workers: Applying a Social Ecological Framework] [Synopsis Promoting Integrated Approaches to Reducing Health Inequities Among Low-Income Workers: Applying a Social Ecological Framework] Baron SL, Beard S, Davis LK, Delp L, Forst L, Kidd-Taylor A, Liebman AK, Linnan L, Punnett L, Welch LS.
. March 2013

Systems Biology and Birth Defects Prevention: Blockade of the Glucocorticoid Receptor Prevents Arsenic-Induced Birth Defects [Abstract Systems Biology and Birth Defects Prevention: Blockade of the Glucocorticoid Receptor Prevents Arsenic-Induced Birth Defects] [Synopsis Systems Biology and Birth Defects Prevention: Blockade of the Glucocorticoid Receptor Prevents Arsenic-Induced Birth Defects] Ahir BK, Sanders AP, Rager JE, Fry RC. March 2013

The Effect of Misunderstanding the Chemical Properties of Environmental Contaminants on Exposure Beliefs: A Case Involving Dioxins [Abstract The Effect of Misunderstanding the Chemical Properties of Environmental Contaminants on Exposure Beliefs: A Case Involving Dioxins] [Synopsis The Effect of Misunderstanding the Chemical Properties of Environmental Contaminants on Exposure Beliefs: A Case Involving Dioxins] Zikmund-Fisher BJ, Turkelson A, Franzblau A, Diebol JK, Allerton LA, Parker EA. March 2013

Topoisomerase 1-Mediated Removal of Ribonucleotides from Nascent Leading-Strand DNA [Abstract Topoisomerase 1-Mediated Removal of Ribonucleotides from Nascent Leading-Strand DNA] [Synopsis Topoisomerase 1-Mediated Removal of Ribonucleotides from Nascent Leading-Strand DNA] Williams JS, Smith DJ, Marjavaara L, Lujan SA, Chabes A, Kunkel TA. March 2013

DNA Polymerase Minor Groove Interactions Modulate Mutagenic Bypass of a Templating 8-oxoguanine Lesion [Abstract DNA Polymerase Minor Groove Interactions Modulate Mutagenic Bypass of a Templating 8-oxoguanine Lesion] [Synopsis DNA Polymerase Minor Groove Interactions Modulate Mutagenic Bypass of a Templating 8-oxoguanine Lesion] Freudenthal BD, Beard WA, Wilson SH. February 2013

Endocrine-Disrupting Chemicals (EDCs): In Vitro Mechanism of Estrogenic Activation and Differential Effects on ER Target Genes [Abstract Endocrine-Disrupting Chemicals (EDCs): In Vitro Mechanism of Estrogenic Activation and Differential Effects on ER Target Genes] [Synopsis Endocrine-Disrupting Chemicals (EDCs): In Vitro Mechanism of Estrogenic Activation and Differential Effects on ER Target Genes] Li Y, Luh CJ, Burns KA, Arao Y, Jiang Z, Teng CT, Tice RR, Korach KS. February 2013

Paternal Obesity is Associated With IGF2 Hypomethylation in Newborns: Results From a Newborn Epigenetics Study (NEST) Cohort [Abstract Paternal Obesity is Associated With IGF2 Hypomethylation in Newborns: Results From a Newborn Epigenetics Study (NEST) Cohort] [Synopsis Paternal Obesity is Associated With IGF2 Hypomethylation in Newborns: Results From a Newborn Epigenetics Study (NEST) Cohort] Soubry A, Schildkraut JM, Murtha A, Wang F, Huang Z, Bernal A, Kurtzberg J, Jirtle RL, Murphy SK, Hoyo C. February 2013

Unexpected Results in a Randomized Dietary Trial to Reduce Phthalate and Bisphenol A Exposures [Abstract Unexpected Results in a Randomized Dietary Trial to Reduce Phthalate and Bisphenol A Exposures] [Synopsis Unexpected Results in a Randomized Dietary Trial to Reduce Phthalate and Bisphenol A Exposures] Sathyanarayana S, Alcedo G, Saelens BE, Zhou C, Dills RL, Yu J, Lanphear B. February 2013

Aldehyde Dehydrogenase Inhibition as a Pathogenic Mechanism in Parkinson Disease [Abstract Aldehyde Dehydrogenase Inhibition as a Pathogenic Mechanism in Parkinson Disease] [Synopsis Aldehyde Dehydrogenase Inhibition as a Pathogenic Mechanism in Parkinson Disease] Fitzmaurice AG, Rhodes SL, Lulla A, Murphy NP, Lam HA, O’Donnell KC, Barnhill L, Casida JE, Cockburn M, Sagasti A, Stahl MC, Maidment NT, Ritz B, Bronstein JM. January 2013

CD11b/CD18 (Mac-1) is a Novel Surface Receptor for Extracellular Double-Stranded RNA to Mediate Cellular Inflammatory Responses [Abstract CD11b/CD18 (Mac-1) is a Novel Surface Receptor for Extracellular Double-Stranded RNA to Mediate Cellular Inflammatory Responses] [Synopsis CD11b/CD18 (Mac-1) is a Novel Surface Receptor for Extracellular Double-Stranded RNA to Mediate Cellular Inflammatory Responses] Zhou H, Liao J, Aloor J, Nie H, Wilson BC, Fessler MB, Gao HM, Hong JS. January 2013

Designing Endocrine Disruption Out of the Next Generation of Chemicals [Abstract Designing Endocrine Disruption Out of the Next Generation of Chemicals] [Synopsis Designing Endocrine Disruption Out of the Next Generation of Chemicals] Schug TT, Abagyan R, Blumberg B, Collins TJ, Crews D, DeFur PL, Dickerson SM, Edwards TM, Gore AC, Guillette LJ, Hayes T, Heindel JJ, Moores A, Patisaul HB, Tal TL, Thayer KA, Vandenberg LN, Warner JC, Watson CS, vom Saal FS, Zoeller RT, O’Brien KP, Myers JP. January 2013

Economic Benefits of Methylmercury Exposure Control in Europe: Monetary Value of Neurotoxicity Prevention [Abstract Economic Benefits of Methylmercury Exposure Control in Europe: Monetary Value of Neurotoxicity Prevention] [Synopsis Economic Benefits of Methylmercury Exposure Control in Europe: Monetary Value of Neurotoxicity Prevention] Bellander M, Pichery C, Aerts D, Berglund M, Castano A, Cejchanova M, Crettaz P, Davidson F, Esteban M, Exley K, Fisher ME, Gurzau AE, Halzlova K, Katsonouri A, Knudsen LE, Kolossa-Gehring M, Koppen G, Ligocka D, Miklavcic A, Reis MF, Rudnai P, Tratnik JS, Weihe P, Budtz-Jorgensen E, Grandjean P. January 2013

Effect of Air Pollution Control on Life Expectancy in the United States: An Analysis of 545 U.S. Counties for the Period from 2000 to 2007 [Abstract Effect of Air Pollution Control on Life Expectancy in the United States: An Analysis of 545 U.S. Counties for the Period from 2000 to 2007] [Synopsis Effect of Air Pollution Control on Life Expectancy in the United States: An Analysis of 545 U.S. Counties for the Period from 2000 to 2007] Correia AW, Pope CA 3rd, Dockery DW, Wang Y, Ezzati M, Dominici F. January 2013

Functional Regulation of ClC-3 in the Migration of Vascular Smooth Muscle Cells [Abstract Functional Regulation of ClC-3 in the Migration of Vascular Smooth Muscle Cells] [Synopsis Functional Regulation of ClC-3 in the Migration of Vascular Smooth Muscle Cells] Ganapathi SB, Wei SG, Zaremba A, Lamb FS, Shears SB. January 2013

SOD1 Integrates Signals From Oxygen and Glucose To Repress Respiration [Abstract SOD1 Integrates Signals From Oxygen and Glucose To Repress Respiration] [Synopsis SOD1 Integrates Signals From Oxygen and Glucose To Repress Respiration] Reddi AR, Culotta VC. January 2013

Traffic-Related Air Pollution, Particulate Matter, and Autism [Abstract Traffic-Related Air Pollution, Particulate Matter, and Autism] [Synopsis Traffic-Related Air Pollution, Particulate Matter, and Autism] Volk HE, Lurmann F, Penfold B, Hertz-Picciotto I, McConnell R. January 2013

Transgenerational Inheritance of Increased Fat Depot Size, Stem Cell Reprogramming, and Hepatic Steatosis Elicited by Prenatal Exposure to the Obesogen Tributyltin in Mice [Abstract Transgenerational Inheritance of Increased Fat Depot Size, Stem Cell Reprogramming, and Hepatic Steatosis Elicited by Prenatal Exposure to the Obesogen Tributyltin in Mice] [Synopsis Transgenerational Inheritance of Increased Fat Depot Size, Stem Cell Reprogramming, and Hepatic Steatosis Elicited by Prenatal Exposure to the Obesogen Tributyltin in Mice] Chamorro-Garcia R, Sahu M, Abbey RJ, Laude J, Pham N, Blumberg B. January 2013

Bridging Environmental Mixtures and Toxic Effect [Abstract Bridging Environmental Mixtures and Toxic Effect] [Synopsis Bridging Environmental Mixtures and Toxic Effect] Allan SE, Smith BW, Tanguay RL, Anderson KA. December 2012

Case-Sibling Studies That Acknowledge Unstudied Parents and Permit the Inclusion of Unmatched Individuals [Abstract Case-Sibling Studies That Acknowledge Unstudied Parents and Permit the Inclusion of Unmatched Individuals] [Synopsis Case-Sibling Studies That Acknowledge Unstudied Parents and Permit the Inclusion of Unmatched Individuals] Shi M, Umbach DM, Weinberg CR. December 2012

Development of the Mammalian Axial Skeleton Requires Signaling Through the Galpha(i) Subfamily of Heterotrimeric G Proteins [Abstract Development of the Mammalian Axial Skeleton Requires Signaling Through the Galpha(i) Subfamily of Heterotrimeric G Proteins] [Synopsis Development of the Mammalian Axial Skeleton Requires Signaling Through the Galpha(i) Subfamily of Heterotrimeric G Proteins] Plummer NW, Spicher K, Malphurs J, Akiyama H, Abramowitz J, Nurnberg B, Birnbaumer L. December 2012

Genome-Wide Joint Meta-Analysis of SNP and SNP-by-smoking Interaction Identifies Novel Loci for Pulmonary Function [Abstract Genome-Wide Joint Meta-Analysis of SNP and SNP-by-smoking Interaction Identifies Novel Loci for Pulmonary Function] [Synopsis Genome-Wide Joint Meta-Analysis of SNP and SNP-by-smoking Interaction Identifies Novel Loci for Pulmonary Function] Hancock DB, Artigas MS, Gharib SA, Henry A, Manichaikul A, Ramasamy A, et al.,. December 2012

Household Light Makes Global Heat: High Black Carbon Emissions from Kerosene Wick Lamps [Abstract Household Light Makes Global Heat: High Black Carbon Emissions from Kerosene Wick Lamps] [Synopsis Household Light Makes Global Heat: High Black Carbon Emissions from Kerosene Wick Lamps] Lam NL, Chen Y, Weyant C, Venkataraman C, Sadavarte P, Johnson MA, Smith KR, Brem BT, Arineitwe J, Ellis JE, Bond TC. December 2012

Leptin Is Key to Peroxynitrate-Mediated Oxidative Stress and Kupffer Cell Activation in Experimental Non-Alchoholic Steatohepatitis [Abstract Leptin Is Key to Peroxynitrate-Mediated Oxidative Stress and Kupffer Cell Activation in Experimental Non-Alchoholic Steatohepatitis] [Synopsis Leptin Is Key to Peroxynitrate-Mediated Oxidative Stress and Kupffer Cell Activation in Experimental Non-Alchoholic Steatohepatitis] Chatterjee S, Ganini D, Tokar EJ, Kumar A, Das S, Corbett J, Kadiiska MB, Waalkes MP, Diehl AM, Mason RP. December 2012

Mechanism of Repair of 5’-Topoisomerase II-DNA Adducts by Mammalian Tyrosyl-DNA Phosphodiesterase 2 [Abstract Mechanism of Repair of 5’-Topoisomerase II-DNA Adducts by Mammalian Tyrosyl-DNA Phosphodiesterase 2] [Synopsis Mechanism of Repair of 5’-Topoisomerase II-DNA Adducts by Mammalian Tyrosyl-DNA Phosphodiesterase 2] Schellenberg MJ, Appel CD, Adhikari S, Robertson PD, Ramsden DA, Williams RS. December 2012

Transactivating Function (AF) 2-Mediated AF-1 Activity of Estrogen Receptor Alpha is Crucial to Maintain Male Reproduction Tract Function [Abstract Transactivating Function (AF) 2-Mediated AF-1 Activity of Estrogen Receptor Alpha is Crucial to Maintain Male Reproduction Tract Function] [Synopsis Transactivating Function (AF) 2-Mediated AF-1 Activity of Estrogen Receptor Alpha is Crucial to Maintain Male Reproduction Tract Function] Arao Y, Hamilton KJ, Goulding EH, Janardhan KS, Eddy EM, Korach KS. December 2012

Accumulation and Endocrine Disrupting Effects of the Flame Retardant Mixture Firemaster® 550 in Rats: An Exploratory Assessment [Abstract Accumulation and Endocrine Disrupting Effects of the Flame Retardant Mixture Firemaster® 550 in Rats: An Exploratory Assessment] [Synopsis Accumulation and Endocrine Disrupting Effects of the Flame Retardant Mixture Firemaster® 550 in Rats: An Exploratory Assessment] Patisaul HB, Roberts SC, Mabrey N, McCaffrey KA, Gear RB, Braun J, Belcher SM, Stapleton HM. November 2012

An Ultraviolet-Radiation-Independent Pathway to Melanoma Carcinogenesis in the Red Hair/Fair Skin Background [Abstract An Ultraviolet-Radiation-Independent Pathway to Melanoma Carcinogenesis in the Red Hair/Fair Skin Background] [Synopsis An Ultraviolet-Radiation-Independent Pathway to Melanoma Carcinogenesis in the Red Hair/Fair Skin Background] Mitra D, Luo X, Morgan A, Wang J, Hoang MP, Lo J, Guerrero CR, Lennerz JK, Mihm MC, Wargo JA, Robinson KC, Devi SP, Vanover JC, D’Orazio JA, McMahon M, Bosenberg MW, Haigis KM, Haber DA, Wang Y, Fisher DE. November 2012

Exposure to Tobacco Smoke In Utero and Subsequent Plasma Lipids, ApoB, and CRP Among Adult Women in the MoBa Cohor [Abstract Exposure to Tobacco Smoke In Utero and Subsequent Plasma Lipids, ApoB, and CRP Among Adult Women in the MoBa Cohor] [Synopsis Exposure to Tobacco Smoke In Utero and Subsequent Plasma Lipids, ApoB, and CRP Among Adult Women in the MoBa Cohor] Cupul-Uicab LA, Skjaerven R, Haug K, Travlos GS, Wilson RE, Eggesbo M, Hoppin JA, Whitworth KW, Longnecker MP. November 2012

Migratory Properties of Pulmonary Dendritic Cells are Determined by Their Developmental Lineage [Abstract Migratory Properties of Pulmonary Dendritic Cells are Determined by Their Developmental Lineage] [Synopsis Migratory Properties of Pulmonary Dendritic Cells are Determined by Their Developmental Lineage] Nakano H, Burgents JE, Nakano K, Whitehead GS, Cheong C, Bortner CD, Cook DN. November 2012

The Toll-like Receptor 5 Ligand Flagellin Promotes Asthma by Priming Allergic Responses to Indoor Allergens [Abstract The Toll-like Receptor 5 Ligand Flagellin Promotes Asthma by Priming Allergic Responses to Indoor Allergens] [Synopsis The Toll-like Receptor 5 Ligand Flagellin Promotes Asthma by Priming Allergic Responses to Indoor Allergens] Wilson RH, Maruoka S, Whitehead GS, Foley JF, Flake GP, Sever ML, Zeldin DC, Kraft M, Garantziotis S, Nakano H, Cook DN. November 2012

Bisphenol A Alters Early Oogenesis and Follicle Formation in the Fetal Ovary of the Rhesus Monkey [Abstract Bisphenol A Alters Early Oogenesis and Follicle Formation in the Fetal Ovary of the Rhesus Monkey] [Synopsis Bisphenol A Alters Early Oogenesis and Follicle Formation in the Fetal Ovary of the Rhesus Monkey] Hunt PA, Lawson C, Gieske M, Murdoch B, Smith H, Marre A, Hassold T, Vandevoort CA. October 2012

Coplanar Polychlorinated Biphenyls Impair Glucose Homeostasis in Lean C57BL/6 Mice and Mitigate Beneficial Effects of Weight Loss on Glucose Homeostasis in Obese Mice [Abstract Coplanar Polychlorinated Biphenyls Impair Glucose Homeostasis in Lean C57BL/6 Mice and Mitigate Beneficial Effects of Weight Loss on Glucose Homeostasis in Obese Mice] [Synopsis Coplanar Polychlorinated Biphenyls Impair Glucose Homeostasis in Lean C57BL/6 Mice and Mitigate Beneficial Effects of Weight Loss on Glucose Homeostasis in Obese Mice] Baker NA, Karounos M, English V, Fang J, Wei Y, Stromberg A, Sunkara M, Morris AJ, Swanson HI, Cassis LA. October 2012

DNA Sequence Context Effects on the Glycosylase Activity of Human 8-oxoguanine DNA Glycosylase [Abstract DNA Sequence Context Effects on the Glycosylase Activity of Human 8-oxoguanine DNA Glycosylase] [Synopsis DNA Sequence Context Effects on the Glycosylase Activity of Human 8-oxoguanine DNA Glycosylase] Sassa A, Beard WA, Prasad R, Wilson SH. October 2012

Glucocorticoids Regulate Arrestin Gene Expression and Redirect the Signaling Profile of G Protein-Coupled Receptors [Abstract Glucocorticoids Regulate Arrestin Gene Expression and Redirect the Signaling Profile of G Protein-Coupled Receptors] [Synopsis Glucocorticoids Regulate Arrestin Gene Expression and Redirect the Signaling Profile of G Protein-Coupled Receptors] Oakley RH, Revollo J, Cidlowski JA. October 2012

Maternal Urinary Bisphenol A during Pregnancy and Maternal and Neonatal Thyroid Function in the CHAMACOS Study [Abstract Maternal Urinary Bisphenol A during Pregnancy and Maternal and Neonatal Thyroid Function in the CHAMACOS Study] [Synopsis Maternal Urinary Bisphenol A during Pregnancy and Maternal and Neonatal Thyroid Function in the CHAMACOS Study] Chevrier J, Gunier RB, Bradman A, Holland NT, Calafat AM, Eskenazi B, Harley KG. October 2012

Mismatch Repair Balances Leading and Lagging Strand DNA Replication Fidelity [Abstract Mismatch Repair Balances Leading and Lagging Strand DNA Replication Fidelity] [Synopsis Mismatch Repair Balances Leading and Lagging Strand DNA Replication Fidelity] Lujan SA, Williams JS, Pursell ZF, Abdulovic-Cui AA, Clark AB, Nick McElhinny SA, Kunkel TA. October 2012