• Livorsi DJ, Nair R, Lund BC, Alexander B, Beck BF, Goto M, Perencevich EN. MRSA prevalence and hospital-level antibiotic use: A retrospective study across 122 acute-care hospitals. Infection control and hospital epidemiology. 2020 Sep 17; 1-3.
• Strymish JM, O' Brien W, Itani K, Gupta K, Branch-Elliman W. What is the Primary Driver of Pre-Operative Vancomycin Use? It's Not MRSA-or Allergy. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2020 Apr 27.
• Jones BE, Ying J, Stevens V, Haroldsen C, He T, Nevers M, Christensen MA, Nelson RE, Stoddard GJ, Sauer BC, Yarbrough PM, Jones MM, Goetz MB, Greene T, Samore MH. Empirical Anti-MRSA vs Standard Antibiotic Therapy and Risk of 30-Day Mortality in Patients Hospitalized for Pneumonia. JAMA internal medicine. 2020 Feb 17.
• Harris AD, Morgan DJ, Pineles L, Perencevich EN, Barnes SL. Deconstructing the relative benefits of a universal glove and gown intervention on MRSA acquisition. The Journal of hospital infection. 2017 May 1; 96(1):49-53.
• Balbale SN, Hill JN, Guihan M, Hogan TP, Cameron KA, Goldstein B, Evans CT. Evaluating implementation of methicillin-resistant Staphylococcus aureus (MRSA) prevention guidelines in spinal cord injury centers using the PARIHS framework: a mixed methods study. Implementation science : IS. 2015 Sep 9; 10:130.

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• Anti-MRSA Therapy Associated with Greater 30-day Mortality Compared with Standard Therapy for Veterans with Pneumonia
  This study sought to determine the association of empirical anti-MRSA therapy with 30-day mortality for Veterans hospitalized with pneumonia. Findings showed that empirical anti-MRSA therapy was significantly associated with greater 30-day mortality compared with standard therapy alone. There was a significant increase in 30-day mortality associated with empirical anti-MRSA therapy plus standard t...
  
  Date: February 17, 2020
• MRSA Prevention Initiative Results in Additional Significant Decline in Other Bacteremia Rates across 130 VHA Facilities
  VA introduced the Methicillin-resistant Staphylococcus aureus (MRSA) Prevention Initiative in 2007. Although the Initiative was perceived as only targeting MRSA, it also expanded infection prevention and control programs and resources, which could result in lower rates of infection with other pathogenic bacteria. This study assessed the effect of the MRSA Initiative on hospital-onset gram-negative...
  
  Date: June 28, 2016
• Targeted Cost-Saving Method for MRSA and VRE Surveillance in VA Hospitals
  Emerging antibiotic-resistant bacteria, including MRSA (methicillin-resistant Staphylococcus aureus) and VRE (vancomycin-resistant enterococcus), are leading causes of infections in hospitalized patients that result in significant costs, morbidity, and mortality. This prospective study investigated alternative methods for targeted active surveillance (using a prediction rule to identify a group of...
  
  Date: December 1, 2010
• Responding to Decline in MRSA Infection
  This JAMA Editorial reports on the current status of MRSA (methicillin-resistant S aureus) infection rates – and what it may mean for the future. Using data from 2005-2008, the CDC’s surveillance system showed a continuous decline of invasive MRSA disease. This includes an estimated 9.4% annual decrease in hospital onset and an estimated 5.7% annual decrease in healthcare-associated community-onse...
  
  Date: August 11, 2010
• Implementation of a VA Quality Improvement Initiative Improves Knowledge and Perceptions Regarding MRSA Prevention
  Implementation of the initiative at 17 VAMCs was associated with temporal improvements in knowledge and perceptions regarding MRSA prevention. Between baseline and follow-up, there were increases in the number of respondents who: correctly identified that alcohol-based hand rub is more effective at inactivating MRSA than soap and water, reported cleaning their hands when entering and exiting a pa...
  
  Date: February 3, 2010

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• FORUM, May 2010: Research and Prevention of Health Care - Associated Infections

  Back to Table of Contents Reducing MRSA Health Care- Associated Infections Rajiv...Rajiv Jain, M.D., Director, VHA MRSA Prevention Program, and Acting Chief Consultant

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• Visit the infectious diseases topic page at the VA Office of Research & Development website to learn more about MRSA research milestones throughout VA.
• Visit the infection prevention section of the VA Office Of Public Health website.