Investigational Drug Accountability Training Videos

PMB is pleased to bring you video tutorials that provide detailed step-by-step guidance on various aspects of drug accountability. Each video covers a different function of the NCI Investigational Agent Accountability Record Form, commonly referred to as the Drug Accountability Record Form (DARF). Whether you're learning for the first time or looking for a refresher on a particular topic, take the time right now to learn about investigational drug accountability.

If you are a person with a disability and are having difficulty experiencing the content of these videos, please contact the Pharmaceutical Management Branch (PMB), CTEP/DCTD/NCI/NIH, by telephone 240-276-6575 Monday through Friday from 8:30am to 4:30pm Eastern Time or by emailing PMBAfterHours@mail.nih.gov at any time.

DARF Basics

• Selection of NCI DARFs
• Use of eDARFs
• Corrections on DARFs
• When separate DARFs are required

DARF Basics Handout (PDF)

Date produced: 09/2014    Length: 05:05

DARF Header

• DARF expiration date
• Dose Form and Strength descriptors
• Bottle Size and Local Protocol Number

DARF Header Handout (PDF)

Date produced: 09/2014    Length: 04:33

Oral DARF

• Agent expiration date
• Patient returns of multiple lots or empty bottles
• Multiple patient returns from single dispensing

Oral DARF Handout (PDF)

Date produced: 09/2014    Length: 06:12

Agent Receipt

• Agent shipping vs. storage conditions
• Agent lot identifiers
• Shipping receipt notes
• Patient-specific agent lot identifier

Agent Receipt Handout (PDF)

Date produced: 09/2014    Length: 06:03

Agent Dispensing

• Study-eligible investigator checklist
• Multiple lots or strengths
• Injectable vial overfill
• Multi-dose vials

Agent Dispensing Handout (PDF)

Date produced: 06/2015    Length: 09:34

Patient-Specific DARFs

• Creating patient-specific DARFs
• Patient registration and initial shipments
• Reordering in OAOP
• Julian dates and inventory management

Patient-Specific DARFs Handout (PDF)

Date produced: 06/2015    Length: 10:14

Agent Transfers

• Reasons for transfer request
• Agent transfer documentation
• Urgent medical need
• Transfer request denials

Agent Transfers Handout (PDF)

Date produced: 06/2015     Length: 07:37

Agent Returns

• Reasons for agent return
• Agent return documentation
• Strategies to reduce the need for returns

Agent Returns Handout (PDF)

Date produced: 08/2016     Length: 07:35

Local Destruction

• Circumstances to request local destruction
• Local destruction authorization and documentation
• Reasons for rescission or denial

Local Destruction Handout (PDF)

Date produced: 08/2016     Length: 05:57