The Office of Intramural Research (OIR) engages in computational science and engineering collaborations with the NIH Intramural Research Program, and provides computational tools and resources for the NIH biomedical research staff. OIR conducts its research and development program through the following organizations: the Office of Director (OD), the High Performance Computing and Informatics Office (HPCIO), the Computational Bioscience and Engineering Laboratory (CBEL), the Center for Molecular Modeling (CMM), Imaging Sciences Laboratory (ISL) and the Mathematical and Statistical Computing Laboratory (MSCL).