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Adoption
AVMA Research Dogs and Cats Adoption – Considerations for developing a research institutional adoption program
Alternatives
ALTBIB, Bibliography on Alternatives to Animal Testing
Alternatives Search: Demonstrating Compliance 
, University of California at Davis
ALTWEB , Alternatives to Animal Testing - Refinement, Reduction and Replacement
Animal Use Alternative Thesaurus, National Agricultural Library, USDA
Center for Alternatives to Animal Testing (CAAT), Johns Hopkins University, School of Public Health
Information Resources for Adjuvants and Antibody Production: Comparisons and Alternative Technologies 1990-1997, Animal Welfare Information Center, USDA
Interagency Coordinating Committee on the Validation of Alternative Methods 
(ICCVAM)
NICEATM and ICCVAM Test Method Evaluations
Norwegian Reference Centre for Laboratory Animal Science and Alternatives (Norecopa)
TSAR , Tracking System for Alternative Test Methods Review, Validation and Approval, European Commission
Databases
AGRICOLA (AGRICultural OnLine Access), USDA
PUBMED, National Library of Medicine
TOXNET, National Library of Medicine
Ethics
Animal Ethics Infolink , Australia
Guidelines for Ethical Conduct in the Care and Use of Nonhuman Animals in Research , APA
Information Resources for Institutional Animal Care and Use Committees 1985-1999: Ethics, USDA
NASA Principles for the Ethical Care and Use of Animals, NASA
National Health and Medical Research Council (NHMRC), Australia
On Being a Scientist: Responsible Conduct in Research , 1995, NAP
The Principles of Humane Experimental Technique , W.M.S. Russell and R.L. Burch, 1959, Johns Hopkins University, School of Public Health
Government
Animal and Plant Health Inspection Service (APHIS), USDA
Animal Care, APHIS, USDA
Animal Welfare Information Center (AWIC), National Agricultural Library, USDA
Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM)
National Institutes of Health (NIH)
Office of Animal Care and Use (OACU), NIH
Laws, Regulations & Policies
Animal Care Policy Manual (PDF - 156 KB), APHIS, USDA [Currently unavailable]
Animal Welfare Regulations (9CFR Chapter 1)
Compliance with the NIH Guidelines for Research Involving Recombinant DNA Molecules
Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES)
Health Research Extension Act of 1985, Public Law 99-158 "Animals in Research"
NASA Principles for the Ethical Care and Use of Animals, NASA
NIH Revitalization Act of 1993, Public Law 103-43, "Plan for Use of Animals in Research" (PDF - 22 KB)
OSHA Standards on Bloodborne Pathogens and Needlestick Prevention
OSHA Standards on Occupational Exposure to Hazardous Chemicals in Laboratories
Public Health Service Policy on Humane Care and Use of Laboratory Animals, 2015 (PDF - 2.95 MB)
Public Law 103-43, Plan for Use of Animals in Research, 1993 (PDF - 22 KB)
Organizations
Academy of Surgical Research (ASR)
American Association for Laboratory Animal Science (AALAS)
American College of Laboratory Animal Medicine (ACLAM)
American Society of Ichthyologists and Herpetologists (ASIH)
American Society of Laboratory Animal Practitioners (ASLAP)
American Society of Mammalogists (ASM)
American Veterinary Medical Association (AVMA)
Americans for Medical Progress (AMP)
Association for Assessment and Accreditation of Laboratory Animal Care International (AAALAC International)
Australian and New Zealand Council for the Care of Animals in Research and Teaching (ANZCCART)
Canadian Association for Laboratory Animal Science (CALAS)
Canadian Council on Animal Care (CCAC)
Federation of Animal Science Societies (FASS)
Foundation for Biomedical Research (FBR)
IACUC Administrators Association (IAA)
Institute for Laboratory Animal Research (ILAR), National Research Council, National Academy of Sciences
Laboratory Animal Management Association (LAMA)
National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs)
Public Responsibility in Medicine and Research (PRIM&R)
Scientists Center for Animal Welfare (SCAW)
States United for Biomedical Research (SUBR)
Universities Federation for Animal Welfare (UFAW)
Publications & Reports
General
- Development of Public Health Service Animal Welfare Policy , 2006, ALN Magazine
- Guide for the Care and Use of Laboratory Animals , 2011, ILAR
- International Guiding Principles for Biomedical Research Involving Animals (PDF - 123 KB), CIOMS/ICLAS
- NIH Plan for the Use of Animals in Research
Animal Facilities
- Cost Analysis and Rate Setting Manual (PDF - 529 KB), NIH
- Guidelines for the Humane Transportation of Research Animals , 2006, ILAR
- NIH Design Requirements Manual
- Strategies That Influence Cost Containment in Animal Research Facilities , 2000, ILAR
Biosafety
Education
- Education and Training in the Care and Use of Laboratory Animals , 1991, ILAR
- Principles and Guidelines for the Use of Animals in Precollege Education (PDF - 244 KB), 1991, ILAR
- Swimming with the Tide: Animal Welfare in Veterinary Medical Education and Research , JVME, Vol. 37, No. 1
- Vertebrate Animals Section Factsheet (PDF - 170 KB)
- What Investigators Need to Know about the Use of Animals (PDF - 349 KB)
Euthanasia
- AVMA Guidelines for the Euthanasia of Animals: 2020 Edition (PDF - 1.4 MB)
Journals and Books
- IACUC Guidebook (PDF - 3.2 MB), 2002, ARENA/OLAW
- Lab Animal
- Laboratory Animals: The International Journal of Laboratory Animal Science and Welfare
- National Academies Press
- Resource Book for the Design of Animal Exercise Protocols , 2006, APS
Occupational Health and Safety
- Criteria for a Recommended Standard: Occupational Exposure to Waste Anesthetic Gases and Vapors, 1977, CDC
- Occupational Health and Safety in the Care and Use of Nonhuman Primates , 2003, ILAR
- Occupational Health and Safety in the Care and Use of Research Animals , 1997, ILAR
OLAW Site Visits
- NIH Guide Notice NOT-OD-19-069: Report on Site Visits to the Veterans Affairs Medical Centers with Focus on Canine Care and Use in Research
- NIH Guide Notice NOT-OD-17-010: Reports on Site Visits to the National Primate Research Centers and the Federally Supported Chimpanzee Sanctuary.
- Federal Chimpanzee Sanctuary Site Visit Report (PDF), October 2016
- Report on OLAW Site Visits to the National Primate Research Centers (PDF), October 2016
- NIH Guide Notice NOT-OD-10-121: Report on Site Visits to Chimpanzee Facilities and Associated Resources to Aid Grantee Institutions.
Pain and Distress
- Definition of Pain and Distress and Reporting Requirements for Laboratory Animals: Proceedings of the Workshop Held 6/22/00 , ILAR
- Grimace Scales: Mouse, Rabbit, and Rat , NC3Rs
- Recognition and Alleviation of Distress in Laboratory Animals , 2008, ILAR
- Recognition and Alleviation of Pain in Laboratory Animals , 2009, ILAR
Research Related
- Corrositex®: Test Method for Dermal Corrosivity Testing, ICCVAM
- Essentials for Animal Research , B. T. Bennett, M. J. Brown and J. C. Schofield
- Guidance for the Description of Animal Research in Scientific Publications , 2011, ILAR
- Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research , 2003, ILAR
- Monoclonal Antibody Production (PDF - 337 KB), 1999, ILAR
- National Toxicology Program, NTP
Species Specific
- Animal Care Manuals , Association of Zoos & Aquariums
- Chimpanzees in Biomedical and Behavioral Research: Assessing the Necessity , 2011, IOM
- Chimpanzees in Research - Strategies for their Ethical Care, Management and Use , 1997, ILAR
- Guide for the Care and Use of Agricultural Animals in Research and Teaching (PDF), 2010, FASS
- Guidelines for the Use of Fishes in Research (PDF - 623 KB), 2013, AFS
- Guidelines for Use of Live Amphibians and Reptiles in Field and Laboratory Research (PDF - 92 KB), 2004, ASIH
- Guidelines of the American Society of Mammalogists for the Use of Wild Mammals in Research and Education (PDF - 591 KB), 2016, ASM
- Guidelines on the Care and Use of Wildlife (PDF - 1.1 MB), 2003, CCAC
- Guidelines to the Use of Wild Birds in Research , 2010, The Ornithological Council
- Nonhuman Primate Evaluation and Analysis, NIH, ORIP
- Psychological Well-Being of Nonhuman Primates , 1998, ILAR
- Scientific and Humane Issues in the Use of Random Source Dogs and Cats in Research , 2009, ILAR
Veterinary Care
Resources
Animals in Research, NIH
Comparison of Federal Requirements and Policies (PDF - 57 KB)
Disaster Planning and Response Resources, OLAW
Disaster Response, NIH
IACUC Central , AALAS
International Veterinary Information Service , IVIS
NETVET Veterinary Resources , Washington University
Enrichment and Social Housing, OLAW
Statistical Calculations Resource
Timeline of Laws Related to Animal Subjects, NIH
Zebrafish International Resource Center , ZIRC
Training & Education
Assessing the Health and Welfare of Laboratory Animals , AHWLA, Newcastle University
Certificate in Laboratory Animal Medicine , University of Guelph
Collaborative Institutional Training Initiative , CITI
The Experimental Fish , University of Prince Edward Island
Research Using Vertebrate Animals, NIH
Laboratory Animal Anaesthesia for Minor Procedures , NC3Rs
Laboratory Animal Training Association , LATA
Laboratory Animal Welfare Training Exchange , LAWTE
PHS Policy on Humane Care and Use of Laboratory Animals Tutorial, OLAW
Training in Survival Rodent Surgery (Part I | Part II ), IVIS
Videos
- Working Safely with Nonhuman Primates
- Working with the Laboratory Dog
- Mouse & Rat Humane Restraint and Experimental Techniques
- Training in Survival Rodent Surgery
- Training in Basic Biomethodology for Laboratory Mice
- Training in Basic Biomethodology for Laboratory Rats
Please e-mail suggested links and comments to OLAW: olaw@od.nih.gov
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