Research/Disease Areas (Dollars in millions and rounded) | FY 2016 Actual | FY 2017 Actual | FY 2018 Actual | FY 2019 Actual | FY 2020 Estimated | FY 2021 Estimated | 2017 US Mortality 19/ | 2017 US Prevalence (Standard Error) 19/ |
Acquired Cognitive Impairment
|
$1,132
|
$1,560
|
$1,978
|
$2,423
|
$2,505
|
$2,315
|
-
|
-
|
Acute Respiratory Distress Syndrome
|
$103
|
$107
|
$123
|
$126
|
$132
|
$121
|
10,584
|
-
|
Adolescent Sexual Activity
|
$91
|
$99
|
$96
|
$102
|
$106
|
$98
|
-
|
-
|
Agent Orange & Dioxin
|
$9
|
$11
|
$10
|
$8
|
$8
|
$8
|
-
|
-
|
Aging
|
$3,150
|
$3,572
|
$4,084
|
$4,653
|
$5,195
|
$4,724
|
-
|
-
|
Alcoholism, Alcohol Use and Health 1/
|
$486
|
$500
|
$534
|
$556
|
$577
|
$528
|
72,371
|
-
|
Allergic Rhinitis (Hay Fever)
|
$7
|
$6
|
$5
|
$7
|
$7
|
$7
|
81
|
8.1% (0.22%)
|
ALS
|
$52
|
$78
|
$83
|
$105
|
$111
|
$102
|
-
|
-
|
Alzheimer's Disease
|
$929
|
$1,361
|
$1,789
|
$2,240
|
$2,644
|
$2,406
|
146,894
|
-
|
Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD) 2/
|
$986
|
$1,423
|
$1,911
|
$2,398
|
$2,818
|
$2,564
|
-
|
-
|
Alzheimer's Disease Related Dementias (ADRD) 2/
|
$175
|
$249
|
$387
|
$515
|
$595
|
$549
|
-
|
-
|
American Indian or Alaska Native 22/
|
$180
|
$181
|
$175
|
$214
|
$226
|
$207
|
-
|
-
|
Anorexia
|
$8
|
$10
|
$11
|
$11
|
$12
|
$11
|
126
|
-
|
Anthrax
|
$51
|
$50
|
$43
|
$29
|
$31
|
$28
|
-
|
-
|
Antimicrobial Resistance
|
$420
|
$470
|
$522
|
$577
|
$631
|
$583
|
-
|
-
|
Anxiety Disorders
|
$174
|
$190
|
$213
|
$233
|
$240
|
$220
|
-
|
-
|
Aphasia
|
$30
|
$34
|
$33
|
$43
|
$45
|
$41
|
2,163
|
-
|
Arctic
|
$24
|
$20
|
$24
|
$27
|
$28
|
$25
|
-
|
-
|
Arthritis
|
$248
|
$240
|
$246
|
$268
|
$275
|
$251
|
-
|
23.8% (0.32%)
|
Assistive Technology
|
$296
|
$299
|
$345
|
$385
|
$390
|
$357
|
-
|
-
|
Asthma
|
$266
|
$286
|
$304
|
$313
|
$335
|
$308
|
10,302
|
7.7% (0.20%)
|
Ataxia Telangiectasia
|
$7
|
$10
|
$10
|
$8
|
$9
|
$8
|
17
|
-
|
Atherosclerosis
|
$385
|
$426
|
$417
|
$400
|
$417
|
$380
|
29,893
|
-
|
Attention Deficit Disorder (ADD)
|
$47
|
$54
|
$58
|
$64
|
$70
|
$70
|
85
|
9.4% (0.40%)**
|
Autism
|
$232
|
$245
|
$281
|
$290
|
$314
|
$287
|
290
|
2.3% (0.20%)**
|
Autoimmune Disease
|
$883
|
$934
|
$888
|
$988
|
$1,055
|
$968
|
-
|
-
|
Back Pain
|
$23
|
$30
|
$30
|
$170
|
$125
|
$122
|
-
|
-
|
Basic Behavioral and Social Science
|
$1,804
|
$1,993
|
$2,252
|
$2,561
|
$2,712
|
$2,483
|
-
|
-
|
Batten Disease
|
$5
|
$5
|
$7
|
$6
|
$6
|
$6
|
-
|
-
|
Behavioral and Social Science
|
$4,137
|
$4,547
|
$5,096
|
$6,499
|
$6,698
|
$6,157
|
-
|
-
|
Biodefense 3/
|
$1,951
|
$1,964
|
$2,170
|
$2,353
|
$2,522
|
$2,337
|
-
|
-
|
Bioengineering
|
$3,841
|
$4,106
|
$4,592
|
$5,091
|
$5,339
|
$4,856
|
-
|
-
|
Biomedical Imaging 23/
|
$1,361
|
$2,083
|
$2,207
|
$2,352
|
$2,495
|
$2,267
|
-
|
-
|
Biotechnology
|
$6,433
|
$6,556
|
$6,923
|
$7,219
|
$7,655
|
$6,964
|
-
|
-
|
Bipolar Disorder
|
$90
|
$88
|
$92
|
$89
|
$96
|
$87
|
-
|
-
|
Brain Cancer
|
$310
|
$332
|
$360
|
$359
|
$393
|
$350
|
17,307
|
0.1% (0.02%)
|
Brain Disorders
|
$4,577
|
$5,156
|
$5,882
|
$6,954
|
$7,146
|
$6,568
|
-
|
-
|
Breast Cancer
|
$656
|
$689
|
$721
|
$709
|
$768
|
$694
|
51,816
|
1.6% (0.08%)
|
Breastfeeding, Lactation and Breast Milk
|
+
|
$92
|
$77
|
$85
|
$91
|
$83
|
-
|
-
|
Burden of Illness
|
$85
|
$109
|
$100
|
$110
|
$118
|
$108
|
-
|
-
|
Cachexia
|
$15
|
$20
|
$19
|
$19
|
$20
|
$18
|
11,514
|
-
|
Cancer
|
$5,589
|
$5,980
|
$6,335
|
$6,520
|
$7,120
|
$6,352
|
680,869
|
9.4% (0.22%)
|
Cancer Genomics
|
$861
|
$907
|
$1,031
|
$1,018
|
$1,112
|
$990
|
-
|
-
|
Cannabidiol Research
|
$12
|
$15
|
$19
|
$31
|
$31
|
$30
|
-
|
-
|
Cannabinoid Research
|
$115
|
$140
|
$147
|
$189
|
$196
|
$187
|
-
|
-
|
Cardiovascular
|
$2,108
|
$2,197
|
$2,269
|
$2,394
|
$2,496
|
$2,273
|
1,529,083
|
-
|
Caregiving Research
|
$74
|
$87
|
$121
|
$151
|
$158
|
$144
|
-
|
-
|
Cerebral Palsy
|
$26
|
$26
|
$26
|
$28
|
$29
|
$26
|
3,529
|
0.2% (0.06%)**
|
Cerebrovascular
|
$520
|
$610
|
$718
|
$759
|
$800
|
$729
|
246,352
|
-
|
Cervical Cancer
|
$99
|
$114
|
$112
|
$106
|
$115
|
$104
|
4,722
|
1.0% (0.08%)
|
Charcot-Marie-Tooth Disease
|
$11
|
$10
|
$12
|
$13
|
$14
|
$13
|
-
|
-
|
Child Abuse and Neglect Research
|
$29
|
$29
|
$41
|
$43
|
$45
|
$41
|
-
|
-
|
Childhood Leukemia
|
$151
|
$177
|
$197
|
$178
|
$198
|
$172
|
-
|
-
|
Childhood Obesity
|
+
|
+
|
$245
|
$266
|
$289
|
$266
|
-
|
-
|
Chronic Fatigue Syndrome (ME/CFS)
|
$8
|
$15
|
$14
|
$15
|
$16
|
$15
|
18
|
-
|
Chronic Liver Disease and Cirrhosis
|
$293
|
$285
|
$324
|
$351
|
$369
|
$341
|
71,064
|
-
|
Chronic Obstructive Pulmonary Disease
|
$97
|
$100
|
$111
|
$112
|
$117
|
$107
|
306,242
|
6.2% (0.17%)
|
Chronic Pain 14/
|
$410
|
$440
|
$474
|
$856
|
$757
|
$714
|
-
|
30.1% (0.39%)
|
Climate Change 12/
|
$5
|
$7
|
$10
|
$10
|
$10
|
$9
|
-
|
-
|
Climate-Related Exposures and Conditions
|
$156
|
$193
|
$223
|
$235
|
$257
|
$235
|
-
|
-
|
Clinical Research
|
$12,176
|
$12,695
|
$13,870
|
$15,868
|
$16,562
|
$15,117
|
-
|
-
|
Clinical Trials and Supportive Activities 17/
|
$3,476
|
$3,775
|
$5,207
|
$6,058
|
$6,171
|
$5,659
|
-
|
-
|
Colo-Rectal Cancer
|
$274
|
$270
|
$314
|
$294
|
$321
|
$286
|
61,340
|
0.6% (0.06%)
|
Comparative Effectiveness Research
|
$632
|
$685
|
$795
|
$991
|
$953
|
$879
|
-
|
-
|
Complementary and Integrative Health 27/
|
$366
|
$376
|
$448
|
$517
|
$524
|
$482
|
-
|
-
|
Conditions Affecting the Embryonic and Fetal Periods
|
$166
|
$180
|
$244
|
$285
|
$301
|
$278
|
-
|
-
|
Congenital Heart Disease
|
$111
|
$119
|
$117
|
$131
|
$138
|
$126
|
-
|
-
|
Congenital Muscular Dystrophy
|
$10
|
$9
|
$8
|
$10
|
$10
|
$10
|
-
|
-
|
Congenital Structural Anomalies
|
$449
|
$474
|
$495
|
$518
|
$542
|
$494
|
-
|
-
|
Contraception/Reproduction
|
$419
|
$437
|
$496
|
$547
|
$572
|
$522
|
-
|
-
|
Cooley's Anemia
|
$18
|
$18
|
$18
|
$22
|
$23
|
$21
|
-
|
-
|
Cost Effectiveness Research
|
$206
|
$223
|
$231
|
$308
|
$264
|
$244
|
-
|
-
|
Crohn's Disease
|
$64
|
$67
|
$69
|
$76
|
$79
|
$74
|
1,998
|
-
|
Cystic Fibrosis
|
$89
|
$91
|
$83
|
$82
|
$86
|
$79
|
439
|
-
|
Data Science
|
+
|
+
|
*
|
$662
|
$694
|
$683
|
0
|
|
Dementia
|
$1,054
|
$1,470
|
$1,881
|
$2,326
|
$2,402
|
$2,220
|
-
|
-
|
Dental/Oral and Craniofacial Disease
|
$518
|
$541
|
$575
|
$613
|
$640
|
$579
|
-
|
-
|
Depression
|
$410
|
$438
|
$500
|
$578
|
$603
|
$553
|
16,821
|
-
|
Diabetes 4/
|
$1,084
|
$1,108
|
$1,039
|
$1,099
|
$1,179
|
$1,090
|
270,702
|
9.6% (0.22%)
|
Dietary Supplements
|
$294
|
$296
|
$301
|
$293
|
$311
|
$283
|
-
|
-
|
Diethylstilbestrol (DES)
|
$1
|
$4
|
$9
|
$2
|
$2
|
$2
|
-
|
-
|
Digestive Diseases
|
$1,745
|
$1,881
|
$2,242
|
$2,173
|
$2,302
|
$2,106
|
-
|
-
|
Digestive Diseases - (Gallbladder)
|
$11
|
$12
|
$17
|
$16
|
$17
|
$15
|
6,208
|
-
|
Digestive Diseases - (Peptic Ulcer)
|
$9
|
$8
|
$8
|
$8
|
$8
|
$8
|
6,786
|
6.2% (0.17%)
|
Down Syndrome
|
$27
|
$35
|
$60
|
$86
|
$113
|
$105
|
2,364
|
0.1% (0.04%)**
|
Drug Abuse (NIDA Only) 5/
|
$1,049
|
$1,071
|
$1,161
|
$1,621
|
$1,458
|
$1,432
|
-
|
-
|
Duchenne/ Becker Muscular Dystrophy
|
$33
|
$30
|
$32
|
$34
|
$35
|
$32
|
-
|
-
|
Dystonia
|
$16
|
$15
|
$14
|
$18
|
$19
|
$18
|
207
|
-
|
Eating Disorders 6/
|
$28
|
$32
|
$38
|
$44
|
$46
|
$42
|
236
|
-
|
Eczema / Atopic Dermatitis
|
$29
|
$32
|
$35
|
$35
|
$36
|
$34
|
-
|
-
|
Emergency Care
|
$129
|
$139
|
$146
|
$166
|
$165
|
$153
|
-
|
-
|
Emerging Infectious Diseases
|
$2,336
|
$2,591
|
$2,767
|
$2,950
|
$3,110
|
$2,877
|
-
|
-
|
Emphysema
|
$29
|
$27
|
$28
|
$27
|
$28
|
$25
|
16,471
|
1.4% (0.08%)
|
Endocannabinoid System Research
|
$51
|
$63
|
$63
|
$73
|
$77
|
$72
|
-
|
-
|
Endocrine Disruptors
|
$140
|
$177
|
$195
|
$187
|
$204
|
$187
|
-
|
-
|
Endometriosis
|
$10
|
$6
|
$7
|
$13
|
$14
|
$12
|
29
|
-
|
Epilepsy
|
$153
|
$154
|
$184
|
$188
|
$203
|
$185
|
6,468
|
1.9% (0.11%)
|
Estrogen
|
$205
|
$220
|
$230
|
$243
|
$259
|
$236
|
-
|
-
|
Eye Disease And Disorders Of Vision
|
$847
|
$882
|
$963
|
$985
|
$1,027
|
$934
|
-
|
-
|
Facioscapulohumeral Muscular Dystrophy
|
$9
|
$11
|
$11
|
$10
|
$11
|
$10
|
-
|
-
|
Fetal Alcohol Syndrome
|
$29
|
$28
|
$34
|
$34
|
$36
|
$32
|
20
|
-
|
Fibroid Tumors (Uterine)
|
$12
|
$11
|
$13
|
$17
|
$17
|
$16
|
89
|
-
|
Fibromyalgia
|
$11
|
$14
|
$14
|
$13
|
$13
|
$12
|
566
|
-
|
Food Allergies
|
$76
|
$79
|
$59
|
$62
|
$66
|
$61
|
-
|
-
|
Foodborne Illness 7/
|
$116
|
$105
|
$139
|
$141
|
$148
|
$137
|
-
|
-
|
Fragile X Syndrome
|
$44
|
$46
|
$38
|
$37
|
$39
|
$36
|
42
|
-
|
Frontotemporal Dementia (FTD)
|
$65
|
$91
|
$94
|
$158
|
$180
|
$168
|
1,798
|
-
|
Gene Therapy
|
$265
|
$266
|
$315
|
$391
|
$421
|
$372
|
-
|
-
|
Gene Therapy Clinical Trials
|
$32
|
$34
|
$52
|
$46
|
$49
|
$45
|
-
|
-
|
Genetic Testing
|
$165
|
$148
|
$151
|
$183
|
$200
|
$170
|
-
|
-
|
Genetics
|
$8,070
|
$8,501
|
$9,105
|
$9,864
|
$10,477
|
$9,496
|
-
|
-
|
Headaches
|
$24
|
$30
|
$32
|
$40
|
$38
|
$35
|
-
|
-
|
Health Disparities 8/
|
$3,093
|
$3,168
|
$3,178
|
$3,381
|
$3,546
|
$3,235
|
-
|
-
|
Health Effects of Household Energy Combustion
|
$17
|
$17
|
$20
|
$20
|
$22
|
$20
|
-
|
-
|
Health Effects of Indoor Air Pollution
|
$103
|
$104
|
$111
|
$112
|
$119
|
$109
|
-
|
-
|
Health Services
|
$1,692
|
$1,770
|
$1,971
|
$2,310
|
$2,328
|
$2,110
|
-
|
-
|
Hearing Loss
|
+
|
+
|
*
|
$163
|
$169
|
$154
|
0
|
|
Heart Disease
|
$1,289
|
$1,370
|
$1,403
|
$1,443
|
$1,504
|
$1,370
|
1,221,921
|
11.5% (0.25%)
|
Heart Disease - Coronary Heart Disease
|
$419
|
$444
|
$444
|
$421
|
$438
|
$399
|
541,008
|
4.4% (0.15%)
|
Hematology
|
$1,317
|
$1,385
|
$1,464
|
$1,474
|
$1,574
|
$1,420
|
-
|
-
|
Hepatitis
|
$267
|
$306
|
$349
|
$378
|
$390
|
$362
|
-
|
2.7% (0.13%)
|
Hepatitis - A
|
$3
|
$4
|
$5
|
$3
|
$3
|
$3
|
91
|
-
|
Hepatitis - B
|
$47
|
$42
|
$55
|
$67
|
$71
|
$66
|
1,727
|
-
|
Hepatitis - C
|
$107
|
$114
|
$129
|
$150
|
$149
|
$140
|
17,253
|
-
|
HIV/AIDS 9/
|
$3,000
|
$3,000
|
$2,995
|
$3,037
|
$3,076
|
$2,813
|
7,803
|
-
|
Hodgkin's Disease
|
$15
|
$12
|
$14
|
$12
|
$13
|
$12
|
1,467
|
-
|
Homelessness
|
$17
|
$17
|
$18
|
$17
|
$18
|
$16
|
-
|
-
|
Homicide and Legal Interventions
|
$1
|
$1
|
$2
|
$3
|
$3
|
$3
|
-
|
-
|
HPV and/or Cervical Cancer Vaccines
|
$38
|
$59
|
$37
|
$40
|
$45
|
$38
|
-
|
-
|
Human Fetal Tissue 11/
|
$103
|
$98
|
$115
|
$109
|
$116
|
$107
|
-
|
-
|
Human Genome
|
$3,200
|
$3,274
|
$3,626
|
$3,895
|
$4,134
|
$3,720
|
-
|
-
|
Huntington's Disease
|
$37
|
$47
|
$52
|
$48
|
$52
|
$47
|
1,305
|
-
|
Hydrocephalus
|
$8
|
$11
|
$10
|
$10
|
$11
|
$10
|
-
|
-
|
Hyperbaric Oxygen
|
$3
|
$6
|
$5
|
$4
|
$5
|
$4
|
-
|
-
|
Hypertension
|
$224
|
$235
|
$260
|
$266
|
$278
|
$253
|
472,428
|
26.9% (0.35%)
|
Immunization
|
$1,828
|
$2,382
|
$2,127
|
$2,351
|
$2,510
|
$2,278
|
-
|
-
|
Immunotherapy
|
+
|
+
|
*
|
$1,436
|
$1,559
|
$1,385
|
0
|
|
Infant Mortality
|
$78
|
$96
|
$99
|
$105
|
$118
|
$130
|
-
|
-
|
Infectious Diseases
|
$5,518
|
$5,684
|
$6,024
|
$6,313
|
$6,672
|
$6,161
|
-
|
-
|
Infertility
|
$86
|
$94
|
$120
|
$151
|
$158
|
$144
|
-
|
-
|
Inflammatory Bowel Disease
|
$126
|
$134
|
$144
|
$163
|
$171
|
$158
|
3,275
|
-
|
Influenza
|
$263
|
$301
|
$340
|
$384
|
$423
|
$423
|
8,255
|
-
|
Injury - Childhood Injuries
|
$47
|
$60
|
$145
|
$169
|
$179
|
$163
|
-
|
-
|
Injury - Trauma - (Head and Spine)
|
$192
|
$222
|
$236
|
$262
|
$276
|
$251
|
-
|
-
|
Injury - Traumatic brain injury
|
$105
|
$116
|
$133
|
$134
|
$143
|
$130
|
-
|
-
|
Injury - Unintentional Childhood Injury
|
$26
|
$31
|
$60
|
$67
|
$71
|
$65
|
-
|
-
|
Injury (total) Accidents/Adverse Effects
|
$447
|
$496
|
$639
|
$897
|
$866
|
$802
|
-
|
-
|
Intellectual and Developmental Disabilities (IDD) 15/
|
$418
|
$455
|
$515
|
$564
|
$608
|
$556
|
-
|
4.5% (0.29%)**
|
Interstitial Cystitis
|
$9
|
$10
|
$13
|
$11
|
$11
|
$11
|
36
|
-
|
Kidney Disease
|
$574
|
$592
|
$598
|
$649
|
$671
|
$621
|
-
|
2.1% (0.10%)
|
Lead Poisoning
|
$9
|
$10
|
$10
|
$11
|
$12
|
$11
|
4
|
-
|
Lewy Body Dementia
|
$22
|
$31
|
$38
|
$66
|
$76
|
$71
|
-
|
-
|
Liver Cancer
|
$83
|
$90
|
$113
|
$127
|
$139
|
$124
|
29,790
|
0.0% (0.01%)
|
Liver Disease
|
$635
|
$691
|
$802
|
$851
|
$890
|
$819
|
129,593
|
1.8% (0.10%)
|
Lung
|
$1,604
|
$1,718
|
$1,849
|
$1,946
|
$2,052
|
$1,874
|
-
|
-
|
Lung Cancer
|
$331
|
$352
|
$403
|
$419
|
$457
|
$411
|
156,254
|
0.3% (0.03%)
|
Lupus
|
$97
|
$109
|
$123
|
$121
|
$127
|
$116
|
3,419
|
-
|
Lyme Disease
|
$28
|
$22
|
$30
|
$32
|
$34
|
$53
|
74
|
-
|
Lymphoma
|
$264
|
$266
|
$298
|
$248
|
$270
|
$244
|
26,726
|
0.3% (0.03%)
|
Machine Learning and Artificial Intelligence
|
+
|
+
|
*
|
$585
|
$609
|
$603
|
0
|
|
Macular Degeneration
|
$99
|
$100
|
$105
|
$124
|
$128
|
$117
|
719
|
-
|
Major Depressive Disorder
|
$103
|
$104
|
$107
|
$131
|
$141
|
$129
|
-
|
-
|
Malaria
|
$183
|
$192
|
$202
|
$196
|
$208
|
$192
|
14
|
-
|
Malaria Vaccine
|
$47
|
$61
|
$57
|
$58
|
$61
|
$57
|
-
|
-
|
Maternal Health
|
+
|
$249
|
$303
|
$334
|
$345
|
$316
|
-
|
-
|
Mental Health
|
$2,454
|
$2,717
|
$3,010
|
$3,296
|
$3,504
|
$3,194
|
-
|
-
|
Mental Illness
|
$826
|
$882
|
$972
|
$1,063
|
$1,123
|
$1,028
|
-
|
-
|
Methamphetamine
|
$50
|
$48
|
$49
|
$47
|
$48
|
$98
|
-
|
-
|
Microbiome
|
+
|
+
|
*
|
$766
|
$812
|
$745
|
0
|
|
Migraines
|
$18
|
$22
|
$21
|
$28
|
$27
|
$25
|
-
|
15.0% (0.28%)
|
Mind and Body
|
$230
|
$279
|
$326
|
$390
|
$401
|
$368
|
-
|
-
|
Minority Health 8/
|
$2,712
|
$2,934
|
$3,065
|
$3,188
|
$3,378
|
$3,074
|
-
|
-
|
Mucopolysaccharidoses (MPS)
|
$7
|
$7
|
$9
|
$8
|
$8
|
$7
|
70
|
-
|
Multiple Sclerosis
|
$97
|
$111
|
$112
|
$111
|
$118
|
$109
|
6,448
|
-
|
Muscular Dystrophy
|
$79
|
$81
|
$81
|
$83
|
$88
|
$80
|
1,244
|
-
|
Myasthenia Gravis
|
$5
|
$5
|
$4
|
$5
|
$6
|
$5
|
1,837
|
-
|
Myotonic Dystrophy
|
$9
|
$11
|
$13
|
$12
|
$13
|
$11
|
-
|
-
|
Nanotechnology 12/
|
$398
|
$444
|
$540
|
$650
|
$686
|
$623
|
-
|
-
|
Neck Pain
|
$1
|
$2
|
*
|
$2
|
$1
|
$1
|
-
|
-
|
Neonatal Respiratory Distress 20/
|
$52
|
$62
|
$62
|
$79
|
$71
|
$65
|
875
|
-
|
Networking and Information Technology R&D 12/ (NITRD)
|
$1,039
|
$1,149
|
$1,274
|
$1,550
|
$1,592
|
$1,451
|
-
|
-
|
Neuroblastoma
|
$37
|
$53
|
$52
|
$58
|
$64
|
$56
|
-
|
-
|
Neurodegenerative
|
$2,058
|
$2,554
|
$3,085
|
$3,578
|
$3,682
|
$3,392
|
-
|
-
|
Neurofibromatosis
|
$29
|
$31
|
$31
|
$36
|
$39
|
$36
|
303
|
-
|
Neurosciences
|
$6,460
|
$7,317
|
$8,224
|
$9,468
|
$10,009
|
$9,147
|
-
|
-
|
Nutrition
|
$1,615
|
$1,708
|
$1,830
|
$1,931
|
$2,044
|
$1,878
|
-
|
-
|
Obesity
|
$965
|
$999
|
$1,055
|
$1,109
|
$1,173
|
$1,080
|
43,782
|
30.9% (0.39%)
|
Opioid Misuse and Addiction 26/
|
+
|
+
|
$231
|
$811
|
$623
|
$623
|
48,861
|
-
|
Opioids 26/
|
+
|
+
|
$336
|
$978
|
$751
|
$751
|
-
|
-
|
Organ Transplantation
|
$153
|
$170
|
$184
|
$191
|
$201
|
$186
|
-
|
-
|
Orphan Drug
|
$1,536
|
$1,653
|
$1,985
|
$1,999
|
$2,150
|
$1,942
|
-
|
-
|
Osteoarthritis
|
$76
|
$78
|
$77
|
$85
|
$85
|
$77
|
-
|
-
|
Osteogenesis Imperfecta
|
$16
|
$13
|
$12
|
$12
|
$12
|
$11
|
92
|
-
|
Osteoporosis
|
$141
|
$139
|
$152
|
$151
|
$157
|
$143
|
7,536
|
-
|
Otitis Media
|
$16
|
$9
|
$10
|
$13
|
$14
|
$12
|
78
|
-
|
Ovarian Cancer
|
$144
|
$151
|
$159
|
$168
|
$183
|
$165
|
15,346
|
0.4% (0.07%)
|
Paget's Disease
|
$2
|
$2
|
$3
|
$2
|
$3
|
$2
|
195
|
-
|
Pain Research 26/
|
$483
|
$516
|
$605
|
$1,011
|
$924
|
$924
|
-
|
-
|
Pancreatic Cancer
|
$168
|
$199
|
$215
|
$219
|
$239
|
$214
|
46,214
|
0.1% (0.01%)
|
Parkinson's Disease
|
$161
|
$168
|
$193
|
$224
|
$239
|
$218
|
47,478
|
-
|
Patient Safety
|
$1,048
|
$1,099
|
$1,268
|
$1,454
|
$1,494
|
$1,362
|
-
|
-
|
Pediatric
|
$3,959
|
$4,176
|
$4,499
|
$4,922
|
$5,216
|
$4,759
|
-
|
-
|
Pediatric AIDS 9/
|
$175
|
$179
|
$183
|
$179
|
$183
|
$167
|
-
|
-
|
Pediatric Cancer
|
$351
|
$433
|
$514
|
$546
|
$596
|
$596
|
-
|
-
|
Pediatric Cardiomyopathy
|
$27
|
$30
|
$24
|
$25
|
$26
|
$24
|
-
|
-
|
Pediatric Research Initiative
|
$389
|
$568
|
$531
|
$679
|
$709
|
$659
|
-
|
-
|
Pelvic Inflammatory Disease
|
$3
|
$2
|
$7
|
$5
|
$5
|
$5
|
334
|
-
|
Perinatal Period - Conditions Originating in Perinatal Period
|
$569
|
$616
|
$689
|
$784
|
$813
|
$746
|
14,714
|
-
|
Peripheral Neuropathy 18/
|
$122
|
$121
|
$143
|
$202
|
$190
|
$177
|
-
|
-
|
Physical Activity
|
$392
|
$421
|
$507
|
$576
|
$603
|
$550
|
-
|
-
|
Physical Rehabilitation
|
$133
|
$146
|
$167
|
$200
|
$208
|
$189
|
-
|
-
|
Pick's Disease
|
$8
|
$8
|
$8
|
$11
|
$12
|
$11
|
-
|
-
|
Pneumonia
|
$127
|
$114
|
$134
|
$146
|
$153
|
$141
|
150,673
|
-
|
Pneumonia & Influenza
|
$380
|
$408
|
$467
|
$521
|
$567
|
$552
|
158,630
|
-
|
Polycystic Kidney Disease
|
$26
|
$29
|
$31
|
$31
|
$33
|
$30
|
813
|
-
|
Post-Traumatic Stress Disorder (PTSD)
|
$89
|
$101
|
$112
|
$138
|
$138
|
$127
|
1,829
|
-
|
Precision Medicine
|
$785
|
$1,152
|
$1,323
|
$1,795
|
$1,891
|
$1,693
|
-
|
-
|
Pregnancy
|
+
|
$319
|
$419
|
$487
|
$515
|
$473
|
-
|
-
|
Prescription Drug Abuse
|
$51
|
$69
|
$123
|
$223
|
$178
|
$174
|
-
|
-
|
Preterm, Low Birth Weight and Health of the Newborn 21/
|
$240
|
$291
|
$295
|
$374
|
$424
|
$474
|
5,200
|
-
|
Prevention
|
$7,566
|
$8,052
|
$8,757
|
$9,485
|
$9,884
|
$9,061
|
-
|
-
|
Prostate Cancer
|
$253
|
$239
|
$261
|
$263
|
$287
|
$256
|
42,169
|
2.4% (0.15%)
|
Psoriasis
|
$18
|
$17
|
$15
|
$16
|
$17
|
$15
|
480
|
-
|
Radiation Oncology
|
$284
|
$313
|
$332
|
$351
|
$382
|
$344
|
-
|
-
|
Rare Diseases
|
$4,342
|
$4,613
|
$5,227
|
$5,655
|
$6,040
|
$5,486
|
-
|
-
|
Regenerative Medicine
|
$886
|
$939
|
$1,005
|
$1,069
|
$1,131
|
$1,022
|
-
|
-
|
Rehabilitation
|
$532
|
$565
|
$638
|
$744
|
$765
|
$698
|
-
|
-
|
Rett Syndrome
|
$14
|
$15
|
$16
|
$15
|
$16
|
$15
|
64
|
-
|
Reye's Syndrome
|
+
|
+
|
*
|
+
|
-
|
-
|
6
|
-
|
Rheumatoid Arthritis
|
$91
|
$93
|
$92
|
$94
|
$98
|
$89
|
9,267
|
-
|
Rural Health
|
$295
|
$259
|
$338
|
$541
|
$527
|
$478
|
-
|
-
|
Sarcopenia
|
$16
|
$19
|
$21
|
$22
|
$22
|
$20
|
-
|
-
|
Schizophrenia
|
$254
|
$243
|
$248
|
$263
|
$285
|
$259
|
4,434
|
-
|
Scleroderma
|
$18
|
$17
|
$23
|
$24
|
$25
|
$23
|
1
|
-
|
Screening And Brief Intervention For Substance Abuse
|
$35
|
$38
|
$39
|
$61
|
$53
|
$51
|
-
|
-
|
Sepsis 15/
|
$116
|
$125
|
$135
|
$137
|
$144
|
$132
|
203,676
|
-
|
Serious Mental Illness
|
$400
|
$402
|
$419
|
$455
|
$487
|
$444
|
-
|
3.4% (0.13%)
|
Sexual and Gender Minorities (SGM/LGBT*) 10/
|
$166
|
$233
|
$295
|
$258
|
$274
|
$253
|
-
|
-
|
Sexually Transmitted Infections 24/
|
$260
|
$322
|
$354
|
$354
|
$379
|
$345
|
-
|
-
|
Sickle Cell Disease
|
$92
|
$109
|
$104
|
$139
|
$142
|
$130
|
973
|
-
|
Sleep Research
|
$315
|
$327
|
$352
|
$436
|
$449
|
$411
|
-
|
-
|
Small Pox
|
$49
|
$57
|
$13
|
$10
|
$11
|
$10
|
-
|
-
|
Spina Bifida
|
$12
|
$13
|
$14
|
$16
|
$17
|
$15
|
421
|
-
|
Spinal Cord Injury
|
$71
|
$77
|
$78
|
$103
|
$108
|
$98
|
1,321
|
-
|
Spinal Muscular Atrophy
|
$10
|
$11
|
$12
|
$13
|
$14
|
$12
|
157
|
-
|
Stem Cell Research
|
$1,516
|
$1,646
|
$1,824
|
$2,014
|
$2,129
|
$1,934
|
-
|
-
|
Stem Cell Research - Embryonic - Human
|
$206
|
$252
|
$278
|
$306
|
$321
|
$294
|
-
|
-
|
Stem Cell Research - Embryonic - Non-Human
|
$146
|
$129
|
$130
|
$140
|
$148
|
$135
|
-
|
-
|
Stem Cell Research - Induced Pluripotent Stem Cell
|
$374
|
$421
|
$507
|
$607
|
$640
|
$585
|
-
|
-
|
Stem Cell Research - Induced Pluripotent Stem Cell - Human
|
$335
|
$382
|
$468
|
$563
|
$593
|
$542
|
-
|
-
|
Stem Cell Research - Induced Pluripotent Stem Cell - Non-Human
|
$56
|
$59
|
$68
|
$74
|
$79
|
$72
|
-
|
-
|
Stem Cell Research - Nonembryonic - Human
|
$457
|
$484
|
$518
|
$569
|
$605
|
$543
|
-
|
-
|
Stem Cell Research - Nonembryonic - Non-Human
|
$652
|
$704
|
$758
|
$781
|
$824
|
$749
|
-
|
-
|
Stem Cell Research - Umbilical Cord Blood/ Placenta
|
$42
|
$40
|
$39
|
$38
|
$40
|
$37
|
-
|
-
|
Stem Cell Research - Umbilical Cord Blood/ Placenta - Human
|
$33
|
$35
|
$36
|
$36
|
$39
|
$35
|
-
|
-
|
Stem Cell Research - Umbilical Cord Blood/ Placenta - Non-Human
|
$10
|
$6
|
$4
|
$2
|
$2
|
$2
|
-
|
-
|
Stroke
|
$308
|
$331
|
$348
|
$350
|
$372
|
$340
|
205,282
|
-
|
Substance Abuse 13/
|
$1,610
|
$1,636
|
$1,795
|
$2,460
|
$2,283
|
$2,190
|
-
|
-
|
Substance Abuse Prevention
|
$57
|
$53
|
$50
|
$62
|
$63
|
$60
|
-
|
-
|
Sudden Infant Death Syndrome
|
$16
|
$13
|
$7
|
$11
|
$12
|
$11
|
-
|
-
|
Suicide
|
$52
|
$68
|
$96
|
$117
|
$121
|
$111
|
47,284
|
-
|
Suicide Prevention
|
$33
|
$35
|
$51
|
$60
|
$65
|
$59
|
-
|
-
|
Teenage Pregnancy
|
$14
|
$14
|
$17
|
$17
|
$18
|
$17
|
-
|
-
|
Temporomandibular Muscle/Joint Disorder (TMJD)
|
$15
|
$13
|
$14
|
$17
|
$16
|
$15
|
4
|
-
|
Therapeutic Cannabinoid Research
|
$28
|
$36
|
$37
|
$46
|
$48
|
$46
|
-
|
-
|
Tobacco
|
$299
|
$293
|
$302
|
$320
|
$332
|
$309
|
-
|
-
|
Tobacco Smoke and Health 25/
|
$298
|
$293
|
$284
|
$301
|
$312
|
$290
|
-
|
14.0% (0.27%)
|
Topical Microbicides
|
$99
|
$91
|
$86
|
$84
|
$89
|
$83
|
-
|
-
|
Tourette Syndrome
|
$5
|
$6
|
$10
|
$11
|
$12
|
$11
|
14
|
-
|
Transmissible Spongiform Encephalopathy (TSE)
|
$33
|
$32
|
$34
|
$34
|
$36
|
$33
|
584
|
-
|
Transplantation
|
$601
|
$606
|
$650
|
$733
|
$776
|
$709
|
-
|
-
|
Tuberculosis
|
$290
|
$347
|
$403
|
$488
|
$516
|
$478
|
946
|
-
|
Tuberculosis Vaccine
|
$27
|
$29
|
$40
|
$61
|
$64
|
$60
|
-
|
-
|
Tuberous Sclerosis
|
$26
|
$21
|
$23
|
$25
|
$27
|
$24
|
61
|
-
|
Underage Drinking
|
$73
|
$66
|
$87
|
$97
|
$100
|
$92
|
-
|
-
|
Underage Drinking – Prevention & Treatment (NIAAA Only) 16/
|
$55
|
$51
|
$56
|
$58
|
$60
|
$55
|
-
|
-
|
Urologic Diseases
|
$506
|
$515
|
$541
|
$546
|
$587
|
$533
|
-
|
-
|
Usher Syndrome
|
$16
|
$18
|
$18
|
$17
|
$18
|
$16
|
-
|
-
|
Uterine Cancer
|
$50
|
$45
|
$47
|
$36
|
$39
|
$36
|
12,362
|
0.7% (0.07%)
|
Vaccine Related
|
$1,773
|
$1,823
|
$2,022
|
$2,236
|
$2,388
|
$2,166
|
-
|
-
|
Vaccine related (AIDS) 9/
|
$605
|
$562
|
$562
|
$598
|
$609
|
$588
|
-
|
-
|
Vaginal Cancer
|
$5
|
$5
|
$12
|
$4
|
$4
|
$4
|
-
|
-
|
Valley Fever
|
$7
|
$7
|
$6
|
$16
|
$17
|
$15
|
-
|
-
|
Vascular Cognitive Impairment/Dementia
|
$89
|
$130
|
$259
|
$299
|
$347
|
$320
|
-
|
-
|
Vector-Borne Diseases
|
$546
|
$557
|
$630
|
$611
|
$647
|
$642
|
-
|
-
|
Violence Against Women
|
$30
|
$30
|
$32
|
$37
|
$40
|
$36
|
-
|
-
|
Violence Research
|
$111
|
$115
|
$131
|
$141
|
$149
|
$136
|
-
|
-
|
Vulvodynia
|
$2
|
$1
|
$2
|
$2
|
$2
|
$2
|
-
|
-
|
West Nile Virus
|
$46
|
$42
|
$36
|
$24
|
$25
|
$23
|
149
|
-
|
Women's Health 8/
|
$4,540
|
$4,769
|
$5,048
|
$4,469
|
$4,749
|
$4,333
|
-
|
-
|
Youth Violence
|
$46
|
$50
|
$46
|
$48
|
$51
|
$47
|
-
|
-
|
Youth Violence Prevention
|
$17
|
$21
|
$22
|
$24
|
$25
|
$23
|
-
|
-
|
|