How to Use the NCBI BioSystems Database

NCBI BioSystems Database

How to use the BioSystems Database

This page provides quick start guides for some common types of searches.
The BioSystems Help document provides detailed descriptions of the database content, search system, and display formats. The companion tool, FLink, is described in a separate "about" page and in the FLink help document.

List the genes, proteins, and small molecules that are involved in a biological pathway

Find the pathways in which a specific gene or protein is involved

Find the pathways in which a specific small molecule (e.g., salicylic acid) is involved

Retrieve the 3D structures for proteins involved in a biosystem

Find related biosystems that are linked to each other because they share an identical protein sequence or have another relationship

Large scale data processing: input a list of proteins and retrieve ranked list of biosystems (using FLink)

Start with a gene expression study and retrieve a ranked list of biosystems in which the up- or down-regulated genes are involved (using FLink)

Revised 19 September 2016