Resources in This Section
- Preclinical and Clinical Research Resources
- Vaccine, Diagnostics, and Therapeutics
- Basic and Omics Research Resources
Preclinical and Clinical Research Resources
Clinical research is a rigorous process of testing the safety and efficacy of candidate vaccines, diagnostics, and therapies. Only those candidates that have performed exceptionally through basic and preclinical research are approved for clinical trials in humans, and only a small number of those succeed through the many phases and approvals involved in ultimately bringing a product to the market.
NIAID offers tools to assist investigators through clinical research, from primary services such as management, evaluation, and education to supplementary support of the research, protocol policies, and standards. NIAID also offers opportunities for collaboration through existing networks that help to accelerate the clinical development of therapies, vaccines, and diagnostics.
Preclinical Research
Infectious Diseases
Target Development
- Influenza Genome Sequencing Project
- Bioinformatics Resource Centers
- Structural Genomics Centers
- Systems Biology
In Vitro and In Vivo Screening
- Animal Models of Infectious Diseases
- Clinical Laboratory Diagnostics for Invasive Aspergillosis
- Tuberculosis Clinical Diagnostics Research Consortium (CDRC)
- In Vitro Assessment for Antimicrobial Activity
- Malaria Vaccine Production and Support Services
Lead Candidate Development
Non Disease-Specific Services
ClinRegs
Clinical Research
Clinical Research Standards, Policies and Procedures
Non Disease-Specific Standards, Policies and Procedures
Allergy, Immunology, and Transplantation
- Clinical Trials in Organ Transplantation - Standardized Immunologic Assays
- Clinical Islet Transplant Consortium - Master Production Batch Record for Purified Human Islets
HIV/AIDS
- AIDSinfo Clinical Guidelines Portal
- DAIDS Clinical Research Policies and Standard Procedures Documents
Infectious Diseases
Clinical Research Services
Clinical Trials at the NIH Clinical Center
- NIAID Study Reference Kit Mobile App
Non Disease-Specific Services
Allergy, Immunology, and Transplantation
- NIH Center for Human Immunology, Autoimmunity and Inflammation
- DAIT Pharmacy Manual
- Immune Tolerance Network
- NIAID Clinical Genomics Program
HIV/AIDS
- CFAR Network of Integrated Clinical Systems (CNICS)
- NIAID Resources for Evaluating New Technologies for Monitoring HIV-Infected Patients
Infectious Diseases
- Clinical Research Operations and Management Support (CROMS)
- Regulatory Affairs Support
- Statistics and Data Coordinating Center for Clinical Research in Infectious Diseases
- Vaccine and Treatment Evaluation Units
- Phase 1 Clinical Trial Units for Therapeutics
- Phase 1–4 trials, contact Dr. Robert Johnson
- Clinical Agents Repository
- International Clinical Sciences Support Center (ICSSC)
Vaccine, Diagnostics, and Therapeutics
Infectious Diseases
- Clinical Agents Repository
- In Vitro Assessment for Antimicrobial Activity
- Malaria Vaccine Production and Support Services
- Vaccine and Treatment Evaluation Units
- Vaccine Development Services
- Tuberculosis Clinical Diagnostics Research Consortium (CDRC)
- Phase I Clinical Trial Units for Therapeutics
- Therapeutic Development Services
- Topical Microbicide Safety and Efficacy Evaluation in Non-Human Primates
HIV/AIDS
- Global HIV Vaccine Enterprise
- International AIDS Vaccine Initiative
- Nonhuman Primate HIV/SIV Vaccine Trials Database
- NIAID Resources for Evaluating New Technologies for Monitoring HIV-Infected Patients
- Resource Guide for the Development of AIDS Therapies
- Division of AIDS Anti-HIV/OI/TB Therapeutics Database