AIDS Therapies Resource Guide
NIAID provides an array of services to assist investigators developing therapies for the treatment of HIV disease and HIV-associated co-Infections, as well as microbicides for the prevention of HIV transmission. Go to the AIDS Therapies Resource Guide.
Resources to Evaluate New Technologies for Monitoring HIV-infected Patients
Current methods for monitoring HIV-infected patients on antiretroviral therapy are expensive and technologically complex, making it difficult for use in resource-limited countries around the world. To advance the field, NIAID has resources available to assist investigators who wish to evaluate new technologies that are cost-effective, easy to use, and can monitor HIV disease, identify acute/early infection, and differentiate vaccine-induced immunity from HIV infection. Alternative test technologies may also be of interest, including HIV drug resistance testing, diagnosis of co-infecting pathogens, and Pharmacokinetics (PK) and Pharmacodynamics (PD) testing. Go to Resources to Evaluate New Technologies for Monitoring HIV-infected Patients.
Analytical and Computational Tools
HIV Databases
- Branchlength
- Codon Alignment
- Consensus Maker
- ELF/Epitope Location Finder
- ElimDupes/Duplicate Sequence Removal
- Entropy/Shannon Entropy-Two
- FindModel
- Format Converter v2.0.3
- Gap Strip/Squeeze v 2.1.0
- Gene Cutter/Sequence Alignment and Protein Extraction
- Hepitope/HLA-Enriched Possible Epitope
- HIV Align/VirAlign for HIV sequences
- HIV Blast
- HIV Sequence Locator
- HLA Analysis Tools
- Hypermut/Analysis and Detection of APOBEC-induced Hypermutation
- jpHMM at GOBICS ((jumping profile Hidden Markov Model)
- Mosaic Vaccine Tool Suite
- Motif Scan/HIV HLA Anchor Residue Motifs
- N-GlycoSite
- PepMap
- PhyloPlace/Phylogenetic Placement Service
- PhyML interface
- Poisson-Fitter
- PCOORD/Principal Coordinate Analysis
- Quality Control/HIV-1 Sequence Quality Analysis
- QuickAlign
- RIP/Recombinant Identification Program
- SeqPublish/Sequence Alignment Publishing Tool
- SNAP/Synonymous Non-synonymous Analysis Program
- SUDI Subtyping/SUbtyping Distance
- SynchAlign/Synchronize Alignments
- Translate/Translate Nucleotide to Amino Acid Sequences
- TreeRate
- VESPA/Viral Epidemiology Signature Pattern Analysis
Databases, Data Sets, and Ontologies
HIV Databases
- ADRA/Antiviral Drug Resistance Analysis Tool
- Antibody Database
- CTL/CD8+ T-Cell Epitope Database
- Epitope Alignments
- Epitope Tables
- HIV-1 Human Interaction Database at NCBI
- HIV-1 Resistance Mutation Database
- HIV Sequence Alignments
- HLA Analysis Tools
- HLA Typing and Epitope Mapping
- Intra-patient Sequence Search
- Motif Scan/HIV HLA Anchor Residue Motifs
- Sequence Search Interface
- SVG Epitope Maps
- T Helper/CD4+ T-Cell Epitope Database
- HIV-1, Human Protein Interaction Database