Development of Serologic Assays for Human Herpes Virus-8
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Dr. Burbelo and colleagues have developed a technique for rapidly and quantitatively detecting antibody responses in sera to a variety of pathogens using recombinant proteins. We would like to apply this technique to develop an assay for detecting antibodies to HHV-8 (KSHV, the etiologic agents of Kaposi's sarcoma, an AIDS-defining condition). We initially plan to examine samples from patients with Kaposi's sarcoma, since all those patients are almost certainly infected with HHV-8. We are thus using samples from patients with previously diagnosed Kaposi's sarcoma. The samples in question are stored at the NCI FCRF repository operated by SAIC Frederick or in Rockville, MD.
Condition |
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Herpesvirus 8, Human |
Study Type: | Observational |
Official Title: | Development of Serologic Assays for Human Herpes Virus-8 |
Estimated Enrollment: | 100 |
Study Start Date: | October 2006 |
Dr. Burbelo and colleagues have developed a technique for rapidly and quantitatively detecting antibody responses in sera to a variety of pathogens using recombinant proteins. We would like to apply this technique to develop an assay for detecting antibodies to HHV-8 (KSHV, the etiologic agents of Kaposi's sarcoma, an AIDS-defining condition). We initially plan to examine samples from patients with Kaposi's sarcoma, since all those patients are almost certainly infected with HHV-8. We are thus using samples from patients with previously diagnosed Kaposi's sarcoma. The samples in question are stored at the NCI FCRF repository operated by SAIC Frederick or in Rockville, MD.
![](https://webarchive.library.unt.edu/web/20130225174302im_/http://clinicaltrials.gov/ct2/html/images/frame/triangle.gif)
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
- Data analysis only
![](https://webarchive.library.unt.edu/web/20130225174302im_/http://clinicaltrials.gov/ct2/html/images/frame/triangle.gif)
United States, Maryland | |
National Institutes of Health Clinical Center, 9000 Rockville Pike | |
Bethesda, Maryland, United States, 20892 |
Principal Investigator: | Joseph A Kovacs, M.D. | National Institutes of Health Clinical Center (CC) |
![](https://webarchive.library.unt.edu/web/20130225174302im_/http://clinicaltrials.gov/ct2/html/images/frame/triangle.gif)
No publications provided
ClinicalTrials.gov Identifier: | NCT00395278 History of Changes |
Other Study ID Numbers: | 999907018, 07-CC-N018 |
Study First Received: | October 31, 2006 |
Last Updated: | June 13, 2012 |
Health Authority: | United States: Federal Government |
Keywords provided by National Institutes of Health Clinical Center (CC):
KSHV Kaposi's Sarcoma HIV Kaposi Sarcoma |
ClinicalTrials.gov processed this record on February 24, 2013