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Skip Navigation LinksHome > Funding > NIH Categorical Spending

RCDC

Estimates of Funding for Various Research, Condition, and Disease Categories (RCDC)


Table Published: February 10, 2016

The table below displays the annual support level for various research, condition, and disease categories based on grants, contracts, and other funding mechanisms used across the National Institutes of Health (NIH), as well as disease burden data published by the National Center for Health Statistics (NCHS) at the Centers for Disease Control & Prevention (CDC).

At the request of Congress, the NIH embarked on a process to provide better consistency and transparency in the reporting of its funded research. This new process, implemented in 2008 through the Research, Condition, and Disease Categorization (RCDC) system, uses sophisticated text data mining (categorizing and clustering using words and multiword phrases) in conjunction with NIH-wide definitions used to match projects to categories. RCDC use of data mining improves consistency and eliminates the wide variability in defining the research categories reported. The definitions are a list of terms and concepts selected by NIH scientific experts to define a research category. The research category levels represent the NIH’s best estimates based on the category definitions.

In 2016, the NIH added mortality and prevalence data from two sources of consistent and nationally-representative disease statistics provided by NCHS/CDC. These data are reported alongside the budgeting categories to provide the public and policymakers with information that is helpful for understanding the NIH research portfolio and its relationship to public health needs. However, NIH believes that the best way to understand disease burdens is by examining patterns in the larger context of multiple methods and measurements, chosen on a case-by-case basis as appropriate for each disease or condition. Further descriptions of these disease statistics can be found here.

The NIH does not expressly budget by category. The annual estimates reflect amounts that change as a result of science, actual research projects funded, and the NIH budget. The research categories are not mutually exclusive. Individual research projects can be included in multiple categories so amounts depicted within each column of this table do not add up to 100 percent of NIH-funded research.



The table shows historical data for FY 2012 through FY 2015. The FY 2016-2017 estimates are based on RCDC actual data.

Total Number of Research/Disease Areas: 265

Click here for instructions on how to use the data table below.

Search Research/ Disease Areas
SEARCH RESEARCH/ DISEASE AREAS                             Print   Help
Research/Disease Areas
(Dollars in millions and rounded)		FY 2012ActualFY 2013ActualFY 2014ActualFY 2015ActualFY 2016EstimatedFY 2017Estimated2014
US Mortality
19/		2014
US Prevalence (Standard Error) 19/
Acquired Cognitive Impairment + + + $798 $832 $832 - -
Acute Respiratory Distress Syndrome $98 $95 $85 $108 $112 $112 10,709 -
Adolescent Sexual Activity $76 $70 $68 $85 $88 $88 - -
Agent Orange & Dioxin $8 $10 $8 $9 $9 $9 - -
Aging $2,593 $2,429 $2,556 $2,698 $2,807 $2,807 - -
Alcoholism, Alcohol Use and Health 1/ $455 $437 $475 $473 $494 $494 60,442 -
Allergic Rhinitis (Hay Fever) $7 $9 $6 $5 $5 $5 76 8.0% (0.22%)
ALS $44 $39 $48 $49 $52 $52 - -
Alzheimer's Disease $503 $504 $562 $589 $910 $910 115,766 -
Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD) 2/ $0 $0 $0 $631 $991 $991 - -
Alzheimer's Disease Related Dementias (ADRD) 2/ $0 $0 $0 $120 $161 $161 - -
American Indians / Alaska Natives $170 $160 $166 $181 $190 $190 - -
Anorexia $14 $11 $11 $10 $10 $10 114 -
Anthrax $84 $70 $67 $53 $56 $56 - -
Antimicrobial Resistance $377 $325 $277 $310 $413 $413 - -
Anxiety Disorders + + + $156 $163 $163 - -
Aphasia $24 $24 $24 $25 $26 $26 1,510 -
Arctic $23 $19 $16 $14 $14 $14 - -
Arthritis $258 $231 $239 $214 $222 $222 - 22.5% (0.33%)
Assistive Technology $237 $220 $228 $246 $258 $258 - -
Asthma $229 $207 $241 $281 $289 $289 10,022 7.4% (0.20%)
Ataxia Telangiectasia $11 $11 $8 $7 $8 $8 8 -
Atherosclerosis $477 $374 $375 $386 $402 $402 33,892 -
Attention Deficit Disorder (ADD) $60 $49 $44 $41 $43 $43 47 8.9% (0.39%)
Autism $192 $186 $188 $208 $216 $216 202 2.2% (0.18%)**
Autoimmune Disease $867 $821 $822 $821 $850 $850 - -
Basic Behavioral and Social Science $1,215 $1,172 $1,234 $1,610 $1,683 $1,683 - -
Batten Disease $4 $5 $5 $5 $6 $6 - -
Behavioral and Social Science $3,682 $3,535 $3,688 $3,762 $3,924 $3,924 - -
Biodefense 3/ $1,791 $1,692 $1,746 $1,736 $1,866 $1,866 - -
Bioengineering $3,498 $3,234 $3,329 $3,540 $3,697 $3,697 - -
Biotechnology $6,089 $5,698 $5,889 $6,018 $6,281 $6,281 - -
Bipolar Disorder + + + $80 $83 $83 - -
Brain Cancer $281 $280 $289 $298 $310 $310 16,358 0.1% (0.02%)
Brain Disorders $3,968 $3,708 $3,894 $3,916 $4,108 $4,108 - -
Breast Cancer $800 $657 $682 $674 $699 $699 50,427 1.4% (0.08%)
Burden of Illness $84 $72 $73 $80 $82 $82 - -
Cancer $5,621 $5,274 $5,392 $5,389 $5,652 $6,332 647,318 8.5% (0.21%)
Cannabidiol Research + + + $9 $9 $9 - -
Cannabinoid Research + + + $111 $115 $115 - -
Cardiovascular $2,040 $1,964 $1,950 $1,991 $2,072 $2,072 1,413,654 -
Cerebral Palsy $42 $18 $21 $20 $21 $21 3,012 0.3% (0.07%)**
Cervical Cancer $112 $98 $116 $99 $103 $106 4,527 1.0% (0.10%)
Charcot-Marie-Tooth Disease $13 $11 $14 $14 $14 $14 - -
Child Abuse and Neglect Research $32 $30 $30 $27 $28 $28 - -
Childhood Leukemia $77 $67 $105 $155 $161 $167 - -
Chronic Fatigue Syndrome (ME/CFS) $5 $5 $5 $6 $7 $7 16 -
Chronic Liver Disease and Cirrhosis $288 $282 $293 $295 $307 $307 64,634 -
Chronic Obstructive Pulmonary Disease $101 $102 $107 $97 $100 $100 278,919 6.2% (0.18%)
Climate Change 12/ $8 $8 $6 $7 $7 $7 - -
Climate-Related Exposures and Conditions 14/ $157 $137 $131 $150 $154 $154 - -
Clinical Research $10,951 $10,604 $11,087 $11,366 $11,867 $11,867 - -
Clinical Trials and Supportive Activities 17/ $3,208 $3,155 $3,221 $3,136 $3,266 $3,266 - -
Colo-Rectal Cancer $302 $281 $271 $309 $321 $331 60,024 0.5% (0.05%)
Comparative Effectiveness Research $597 $559 $610 $587 $611 $611 - -
Complementary and Alternative Medicine $493 $380 $367 $337 $348 $348 - -
Conditions Affecting the Embryonic and Fetal Periods 15/ $165 $151 $175 $200 $204 $204 - -
Congenital Structural Anomalies $0 $0 $0 $404 $420 $420 - -
Contraception/Reproduction $448 $408 $394 $424 $434 $434 - -
Cooley's Anemia $20 $15 $18 $15 $16 $16 - -
Cost Effectiveness Research $78 $82 $70 $175 $182 $182 - -
Crohn's Disease $76 $61 $65 $66 $69 $69 1,762 -
Cystic Fibrosis $86 $78 $77 $80 $83 $83 582 -
Dementia $0 $650 $704 $721 $753 $753 - -
Dental/Oral and Craniofacial Disease $516 $480 $483 $493 $512 $512 - -
Depression $429 $415 $396 $390 $406 $406 14,992 -
Diabetes 4/ $1,061 $1,007 $1,011 $1,010 $1,044 $1,044 245,016 9.3% (0.20%)
Diagnostic Radiology $1,090 $1,079 $1,078 $1,272 $1,320 $1,320 - -
Diethylstilbestrol (DES) $3 $1 $1 $1 $1 $1 - -
Digestive Diseases $1,719 $1,575 $1,607 $1,684 $1,754 $1,754 - -
Digestive Diseases - (Gallbladder) $11 $10 $9 $8 $8 $8 5,775 -
Digestive Diseases - (Peptic Ulcer) $20 $19 $15 $16 $16 $16 6,085 6.7% (0.18%)
Down Syndrome $20 $18 $18 $24 $25 $25 2,083 0.2% (0.04%)
Drug Abuse (NIDA Only) 5/ $1,052 $993 $1,018 $1,016 $1,051 $1,051 - -
Duchenne/ Becker Muscular Dystrophy $34 $33 $32 $30 $32 $32 - -
Dystonia $14 $13 $12 $14 $15 $15 175 -
Eating Disorders 6/ $34 $31 $30 $31 $32 $32 219 -
Eczema / Atopic Dermatitis + + + $27 $28 $28 - -
Emergency Care + + + $122 $128 $128 - -
Emerging Infectious Diseases $2,153 $1,804 $1,930 $2,053 $2,200 $2,200 - -
Emphysema $20 $24 $27 $28 $29 $29 16,352 1.4% (0.08%)
Endometriosis $9 $7 $7 $10 $11 $11 28 -
Epilepsy $156 $129 $154 $138 $145 $145 4,806 -
Estrogen $221 $218 $203 $194 $201 $201 - -
Eye Disease And Disorders Of Vision $841 $774 $824 $779 $815 $815 - -
Facioscapulohumeral Muscular Dystrophy $5 $5 $7 $8 $9 $9 - -
Fetal Alcohol Syndrome $32 $33 $34 $32 $33 $33 14 -
Fibroid Tumors (Uterine) $14 $10 $9 $10 $10 $10 78 -
Fibromyalgia $13 $11 $10 $8 $9 $9 537 -
Food Allergies $31 $36 $35 $39 $41 $41 - 5.4% (0.28%)**
Foodborne Illness 7/ $257 $229 $232 $105 $109 $109 - -
Fragile X Syndrome $27 $30 $36 $38 $40 $40 48 -
Frontotemporal Dementia (FTD) $26 $32 $37 $36 $37 $37 1,237 -
Gene Therapy $256 $226 $253 $238 $248 $250 - -
Gene Therapy Clinical Trials $15 $15 $26 $23 $24 $24 - -
Genetic Testing $255 $272 $231 $161 $167 $167 - -
Genetics $7,632 $7,144 $7,324 $7,480 $7,826 $7,879 - -
Global Warming Climate Change $6 $6 $4 $4 $4 $4 - -
Headaches $24 $25 $24 $24 $25 $25 - -
Health Disparities 8/ $2,740 $2,722 $2,734 $2,825 $2,952 $2,952 - -
Health Effects of Household Energy Combustion + + + $14 $14 $14 - -
Health Effects of Indoor Air Pollution + + + $103 $106 $106 - -
Health Services $1,317 $1,262 $1,342 $1,437 $1,500 $1,500 - -
Heart Disease $1,278 $1,230 $1,224 $1,262 $1,314 $1,314 1,160,624 11.5% (0.23%)
Heart Disease - Coronary Heart Disease $468 $404 $421 $426 $444 $444 530,989 6.0% (0.17%)
Hematology $1,091 $1,020 $1,189 $1,217 $1,264 $1,264 - -
Hepatitis $210 $195 $251 $262 $273 $273 - 2.5% (0.10%)
Hepatitis - A $2 $2 $3 $4 $4 $4 76 -
Hepatitis - B $51 $48 $48 $42 $43 $43 1,837 -
Hepatitis - C $112 $101 $111 $96 $100 $100 19,613 -
HIV/AIDS 9/ $3,074 $2,898 $2,978 $3,000 $3,000 $3,000 8,619 -
Hodgkin's Disease $21 $13 $14 $16 $16 $16 1,553 -
Homelessness $10 $11 $14 $15 $16 $16 - -
Homicide and Legal Interventions $1 $0 $0 $1 $1 $1 - -
HPV and/or Cervical Cancer Vaccines $26 $25 $38 $31 $32 $32 - -
Human Fetal Tissue 11/ $71 $67 $76 $80 $84 $84 - -
Human Genome $2,271 $2,473 $2,701 $2,891 $3,025 $3,025 - -
Huntington's Disease $65 $55 $50 $39 $39 $39 1,257 -
Hydrocephalus $7 $6 $5 $6 $6 $6 - -
Hyperbaric Oxygen $2 $1 $2 $3 $3 $3 - -
Hypertension $215 $222 $216 $214 $222 $222 410,624 26.4% (0.33%)
Immunization $1,733 $1,656 $1,607 $1,617 $1,669 $1,669 - -
Infant Mortality + + + $75 $78 $78 - -
Infant Mortality/ (LBW) $287 $253 $268 $293 $302 $302 - -
Infectious Diseases $3,867 $4,887 $5,002 $5,032 $5,249 $5,249 - -
Infertility $74 $78 $76 $72 $73 $73 - -
Inflammatory Bowel Disease $121 $114 $125 $128 $134 $134 2,922 -
Influenza $251 $304 $262 $280 $285 $285 5,590 -
Injury - Childhood Injuries $37 $37 $35 $39 $41 $41 - -
Injury - Trauma - (Head and Spine) $171 $183 $216 $197 $208 $208 - -
Injury - Traumatic brain injury $79 $88 $87 $93 $99 $99 - -
Injury - Unintentional Childhood Injury $22 $20 $22 $23 $24 $24 - -
Injury (total) Accidents/Adverse Effects $366 $367 $404 $399 $418 $418 - -
Intellectual and Developmental Disabilities (IDD) 15/ $355 $343 $356 $382 $397 $397 - 5.8% (0.30%)**
Interstitial Cystitis $10 $10 $9 $10 $11 $11 24 -
Kidney Disease $556 $551 $549 $564 $586 $586 - 1.9% (0.09%)
Lead Poisoning $8 $8 $7 $7 $8 $8 1 -
Lewy Body Dementia + + $15 $15 $16 $16 - -
Liver Cancer $73 $71 $74 $85 $89 $89 26,794 0.1% (0.02%)
Liver Disease $632 $594 $605 $616 $642 $642 121,243 1.4% (0.08%)
Lung $1,286 $1,230 $1,329 $1,619 $1,678 $1,678 - -
Lung Cancer $233 $208 $254 $349 $362 $362 164,882 0.3% (0.03%)
Lupus $108 $92 $99 $90 $93 $93 3,114 -
Lyme Disease $25 $20 $23 $24 $25 $25 63 -
Lymphoma $213 $233 $251 $270 $281 $281 26,450 0.3% (0.04%)
Macular Degeneration $101 $98 $82 $82 $85 $85 649 -
Major Depressive Disorder + + + $95 $99 $99 - -
Malaria $152 $147 $169 $163 $171 $171 14 -
Malaria Vaccine $40 $34 $36 $44 $46 $46 - -
Mental Health $2,287 $2,174 $2,213 $2,263 $2,381 $2,381 - -
Methamphetamine $69 $68 $63 $58 $60 $60 - -
Migraines $18 $19 $20 $20 $20 $20 - 14.9% (0.28%)
Mind and Body $533 $210 $211 $217 $226 $226 - -
Minority Health 8/ $2,487 $2,428 $2,514 $2,538 $2,653 $2,653 - -
Mucopolysaccharidoses (MPS) $10 $8 $6 $6 $6 $6 75 -
Multiple Sclerosis $115 $112 $102 $94 $98 $98 5,982 -
Muscular Dystrophy $75 $76 $78 $77 $80 $80 1,171 -
Myasthenia Gravis $7 $7 $8 $7 $7 $7 1,513 -
Myotonic Dystrophy $10 $10 $9 $9 $10 $10 - -
Nanotechnology 12/ $456 $430 $409 $364 $381 $381 - -
Networking and Information Technology R&D 12/ $532 $521 $612 $729 $764 $764 - -
Neuroblastoma $34 $33 $37 $32 $33 $33 - -
Neurodegenerative $1,671 $1,619 $1,743 $1,662 $1,744 $1,744 - -
Neurofibromatosis $18 $17 $21 $22 $23 $23 300 -
Neurosciences $5,618 $5,340 $5,580 $5,742 $6,041 $6,041 - -
Nutrition $1,692 $1,524 $1,555 $1,574 $1,631 $1,631 - -
Obesity $836 $812 $857 $900 $931 $931 37,548 28.9% (0.38%)
Organ Transplantation $150 $140 $142 $148 $154 $154 - -
Orphan Drug $809 $764 $809 $785 $817 $817 - -
Osteoarthritis + + + $76 $79 $79 - -
Osteogenesis Imperfecta $9 $8 $11 $11 $11 $11 102 -
Osteoporosis $181 $164 $141 $146 $151 $151 8,601 -
Otitis Media $17 $14 $16 $15 $16 $16 70 -
Ovarian Cancer $147 $133 $131 $118 $123 $123 15,236 0.4% (0.07%)
Paget's Disease $1 $0 $0 $1 $1 $1 162 -
Pain Conditions - Chronic $396 $402 $402 $391 $406 $406 - 28.7% (0.36%)
Pain Research $479 $475 $499 $463 $481 $481 - -
Pancreatic Cancer $127 $125 $123 $174 $181 $181 42,215 -
Parkinson's Disease $154 $135 $139 $146 $152 $152 39,565 -
Patient Safety $845 $858 $1,008 $861 $897 $897 - -
Pediatric $3,612 $3,266 $3,486 $3,632 $3,766 $3,766 - -
Pediatric AIDS 9/ $219 $188 $166 $166 $168 $170 - -
Pediatric Cancer + + $276 $342 $355 $355 - -
Pediatric Research Initiative $379 $258 $343 $512 $522 $522 - -
Pelvic Inflammatory Disease $3 $3 $2 $4 $5 $5 302 -
Perinatal - Birth - Preterm (LBW) $217 $198 $206 $223 $230 $230 5,668 -
Perinatal - Neonatal Respiratory Distress Syndrome $38 $33 $52 $31 $32 $32 778 -
Perinatal Period - Conditions Originating in Perinatal Period $538 $486 $534 $561 $578 $578 15,458 -
Peripheral Neuropathy 18/ $145 $151 $156 $105 $109 $109 - -
Physical Rehabilitation + + $113 $120 $125 $125 - -
Pick's Disease $2 $3 $4 $2 $3 $3 - -
Pneumonia $115 $113 $107 $112 $117 $117 153,911 -
Pneumonia & Influenza $358 $407 $362 $384 $401 $401 159,019 -
Polycystic Kidney Disease $42 $40 $36 $29 $31 $31 763 -
Post-Traumatic Stress Disorder (PTSD) $0 $77 $79 $85 $88 $88 1,262 -
Prescription Drug Abuse $33 $33 $40 $48 $49 $49 - -
Prevention $5,924 $6,686 $6,858 $7,027 $7,300 $7,300 - -
Prostate Cancer $257 $286 $254 $288 $299 $299 39,624 2.0% (0.14%)
Psoriasis $10 $12 $13 $14 $14 $14 402 -
Rare Diseases $3,623 $3,456 $3,639 $3,679 $3,832 $3,832 - -
Regenerative Medicine $877 $831 $836 $862 $898 $898 - -
Rehabilitation $449 $446 $494 $514 $537 $537 - -
Rett Syndrome $13 $13 $12 $12 $12 $12 56 -
Reye's Syndrome $0 $0 $0 $0 - - 6 -
Rheumatoid Arthritis + + + $59 $62 $62 8,878 -
Rural Health $231 $187 $197 $192 $200 $200 - -
Schizophrenia $268 $232 $253 $241 $251 $251 3,836 -
Scleroderma $24 $21 $24 $22 $23 $23 8 -
Screening And Brief Intervention For Substance Abuse $31 $25 $30 $35 $36 $36 - -
Septicemia $96 $88 $100 $103 $108 $108 182,242 -
Serious Mental Illness + + $407 $381 $396 $396 - 3.1% (0.12%)
Sexual and Gender Minorities (SGM/LGBT*) 10/ + + + $162 $169 $169 - -
Sexually Transmitted Diseases/Herpes $275 $242 $263 $250 $260 $260 - -
Sickle Cell Disease $65 $70 $75 $75 $78 $78 844 -
Sleep Research $238 $229 $233 $313 $326 $326 - -
Small Pox $40 $30 $24 $17 $18 $18 0 -
Smoking and Health $353 $321 $320 $298 $308 $308 - 16.8% (0.33%)
Spina Bifida $12 $10 $10 $10 $10 $10 375 -
Spinal Cord Injury $79 $94 $80 $82 $86 $86 1,306 -
Spinal Muscular Atrophy $15 $13 $16 $11 $12 $12 157 -
Stem Cell Research $1,374 $1,273 $1,391 $1,429 $1,495 $1,495 - -
Stem Cell Research - Embryonic - Human $146 $146 $166 $180 $191 $191 - -
Stem Cell Research - Embryonic - Non-Human $164 $154 $150 $159 $168 $168 - -
Stem Cell Research - Induced Pluripotent Stem Cell $206 $228 $313 $324 $339 $339 - -
Stem Cell Research - Induced Pluripotent Stem Cell - Human $175 $199 $280 $282 $296 $296 - -
Stem Cell Research - Induced Pluripotent Stem Cell - Non-Human $48 $43 $49 $61 $63 $63 - -
Stem Cell Research - Nonembryonic - Human $504 $431 $443 $445 $465 $465 - -
Stem Cell Research - Nonembryonic - Non-Human $653 $613 $627 $632 $658 $658 - -
Stem Cell Research - Umbilical Cord Blood/ Placenta $47 $40 $34 $35 $37 $37 - -
Stem Cell Research - Umbilical Cord Blood/ Placenta - Human $43 $35 $28 $32 $32 $32 - -
Stem Cell Research - Umbilical Cord Blood/ Placenta - Non-Human $8 $7 $7 $6 $6 $6 - -
Stroke $310 $282 $300 $288 $300 $300 224,161 2.6% (0.11%)
Substance Abuse 13/ $1,634 $1,525 $1,564 $1,549 $1,607 $1,607 - -
Substance Abuse Prevention $41 $65 $69 $67 $69 $69 - -
Sudden Infant Death Syndrome $24 $20 $20 $17 $18 $18 1,571 -
Suicide $44 $37 $39 $46 $48 $48 42,921 -
Suicide Prevention $22 $21 $22 $24 $25 $25 - -
Teenage Pregnancy $18 $17 $16 $14 $15 $15 - -
Temporomandibular Muscle/Joint Disorder (TMJD) $21 $19 $18 $16 $16 $16 1 -
Therapeutic Cannabinoid Research + + + $21 $22 $22 - -
Tobacco $355 $322 $321 $300 $310 $310 - -
Topical Microbicides $99 $93 $103 $107 $112 $112 - -
Tourette Syndrome $6 $4 $4 $5 $5 $5 12 -
Transmissible Spongiform Encephalopathy (TSE) $39 $35 $33 $36 $37 $37 517 -
Transplantation $552 $538 $561 $582 $606 $606 - -
Tuberculosis $218 $240 $279 $272 $278 $278 903 -
Tuberculosis Vaccine $21 $26 $31 $23 $24 $24 - -
Tuberous Sclerosis $23 $20 $24 $21 $22 $22 51 -
Underage Drinking $80 $75 $83 $74 $77 $77 - -
Underage Drinking – Prevention & Treatment (NIAAA Only) 16/ $62 $62 $59 $52 $54 $54 - -
Urologic Diseases $496 $497 $494 $527 $548 $548 - -
Usher Syndrome + + $19 $16 $17 $17 - -
Uterine Cancer $42 $39 $57 $52 $54 $54 11,013 0.7% (0.08%)
Vaccine Related $1,691 $1,608 $1,573 $1,585 $1,653 $1,653 - -
Vaccine related (AIDS) 9/ $557 $518 $533 $541 $553 $554 - -
Valley Fever + + $3 $11 $11 $11 - -
Vascular Cognitive Impairment/Dementia + + $45 $72 $75 $75 - -
Vector-Borne Diseases $441 $437 $487 $439 $459 $459 - -
Violence Against Women $36 $31 $35 $31 $32 $32 - -
Violence Research $154 $137 $130 $107 $111 $111 - -
Vulvodynia $4 $4 $3 $2 $2 $2 - -
West Nile Virus $29 $40 $48 $40 $42 $42 140 -
Women's Health 8/ $3,833 $3,745 $3,935 $3,989 $4,140 $4,140 - -
Youth Violence $77 $70 $59 $47 $48 $48 - -
Youth Violence Prevention $27 $26 $16 $15 $16 $16 - -
[*] The minimum reporting threshold for a specific disease/condition is $500,000. Reporting of $0 does not indicate that no research is being conducted.
[+] Indicates a new category. Funding support data not available prior to the initial year reported.
1/ Name revised in FY 2015 to account for more inclusive definition of research addressing the harms and benefits related to alcohol use.
2/ New categories established pursuant to Section 230, Division G of the Consolidated and Further Continuing Appropriations Act of 2015 as related to reporting of NIH initiatives supporting the National Alzheimer’s Project Act (NAPA) https://aspe.hhs.gov/national-alzheimers-project-act. The new Alzheimer’s Disease Related Dementias (ADRD) category reflects the sum of the three existing RCDC categories: Frontotemporal Dementia (FTD), Lewy Body Dementia and Vascular Cognitive Impairment/Dementia – where duplicates are removed. The new category Alzheimer’s Disease including Alzheimer’s Disease Related Dementias reflects the sum of the two existing RCDC categories: Alzheimer’s Disease and the above new Alzheimer’s Disease Related Dementias (ADRD) – where duplicates are removed.
3/ Reporting for this category does not follow the standard RCDC process. The total amount reported is consistent with reporting requirements for this category to the U.S. Office of Management & Budget (OMB). The project listing does not include non-project or other support costs associated with the annual total for this category. Additional information on this category is available at http://www.niaid.nih.gov/topics/biodefenserelated/pages/default.aspx.
4/ Includes research funded from the Type 1 diabetes appropriation. These are project listings only.
5/ Reporting for this category does not follow the standard RCDC process. Spending for this category is reported consistent with U.S. Office of National Drug Control Policy (ONDCP) requirements. This category includes only projects funded by NIDA. More information on this area is available at http://www.drugabuse.gov/drugs-abuse. FY 2014 actual and FY 2015 estimate reported in RePORT can differ from levels identified in the FY 2016 Drug Control budget submission for those fiscal years where comparable adjustments have been applied.
6/ Reported total for this category encompasses research for anorexia, bulimia nervosa, binge eating disorders, and eating disorders not otherwise specified.
7/ Name revised in FY 2015 and definition refined. Category merges projects identified as Foodborne Illness with relevant projects from the prior “Food Safety” category. Historical data is maintained in separately to assure that information for predecessor categories is not conflated with the merged category.
8/ Reporting for this category does not follow the standard RCDC process. This category assigns project funding according to populations tracked by gender or ethnicity. The databases used to track gender/ethnicity are complex are not currently compatible with the RCDC system.
9/ The total for AIDS research includes both extramural and intramural research (including research management and support, Management Fund, and Service & Supply Fund), buildings and facilities, research training, and program evaluation, as well as research on the many HIV-associated co-infections and co-morbidities, including TB, hepatitis C, and HIV-associated cancers. It also includes all of the basic science underlying this research. Other RCDC categories are not reported this way; thus the total for AIDS-related research is not comparable to spending reported for other RCDC diseases. More information on this area is available at http://www.oar.nih.gov/hivaids/.
10/ This category includes projects that are focused on basic, pre-clinical, clinical, biomedical, health services, behavioral, and social research relevant to sexual and gender minority (SGM) populations. The SGM population – often referred to as LGBT, is asterisked to recognize the diversity in membership as well as sensitivities associated with the variety of descriptive names in use by the medical communities and general public. LGBT research pertains to people whose sexual orientation is not exclusively heterosexual, i.e. lesbian, gay, and bisexual persons. Research projects can likewise focus on individuals whose gender identity differs from the sex originally assigned to them at birth, gender non-conforming or gender variant, or who may not self-identify as LGBT (such as queer, questioning, two-spirit, asexual, etc.). Research also can cover individuals who are born with conditions in which development of chromosomal, gonadal, or anatomic sex is atypical, i.e. people who identify themselves as intersex or with differences/disorders of sex development (DSD). DSD can include, but are not limited to: Y chromosome aneuploidy, congenital adrenal hyperplasia, complete androgen insensitivity, partial androgen insensitivity, gonadal dysgenesis, mixed gonadal dysgenesis, hypospadias, Klinefelter syndrome, Turner syndrome, 5aRD2 deficiency, aromatase defects, MRKH syndrome and gynecomastia.
11/ Reporting for this category does not follow the standard RCDC process. This category uses a non-standard approach involving subject matter expert reviews of manually collected project listings.
12/ The data provided reflects funding amounts reported by the NIH RCDC process for this category. Actual and estimate levels presented on this site supersede estimates detailed in OMB MAX DE application tables that may have been based on preliminary funding support information.
13/ Reporting for this category does not follow the standard RCDC process. This category includes all spending reported under the Drug Abuse category as well as projects categorized under the broader area of Substance Abuse. These are project listings only. More information on this area is available at http://www.drugabuse.gov/drugs-abuse.
14/ Prior to FY 2011, this category's title was "Health Effects of Climate Change". The title was revised to more accurately reflect the content of the research conducted and facilitate reporting spending data in response to requests tracking climate change adaptation.
15/ Name revised in FY 2013 to reflect current scientific terminology.
16/ Reporting for this category does not follow the standard RCDC process. Spending for this category is reported consistent with U.S. Office of National Drug Control Policy (ONDCP) requirements. This category includes only projects funded and administered by NIAAA. This category represents a subset of spending reported under the RCDC Underage Drinking category and involves manual review of the project listing by subject matter experts. More information on this area is available at http://www.niaaa.nih.gov/research/major-initiatives/underage-drinking-research-initiative. The FY 2015 actual or and FY 2016 estimate display in RePORT can differ from levels identified in the FY 2017 Drug Control budget submission for those fiscal years where either comparable adjustments have been applied or historical data was refined.
17/ Name revised in FY 2015 from “Clinical Trials”.
18/ Name revised in FY 2015 from “Neuropathy”.
19/ Estimates of United States disease burden are provided as mortality and prevalence figures for calendar year 2014. Figures for mortality data are drawn from the National Vital Statistics System (NVSS), and indicate the number of deaths in which a particular disease or condition was mentioned on a deceased individual’s death certificate. Prevalence figures are drawn from National Health Interview Survey (NHIS) responses and report the percentage of respondents who indicated that they were affected by a particular health condition. Standard error, a measure of the uncertainty in the estimate, is presented in parentheses alongside the prevalence estimate. Estimates of mortality and prevalence are not available for all NIH spending categories. Further descriptions of these disease statistics can be found here.
[**] indicates that prevalence for this particular disease or condition was measured only in children <18

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