CATNAP

Compile, Analyze and Tally NAb Panels

The CATNAP family of tools has been designed to facilitate the analysis of neutralizing antibodies (NAbs) through the identification of potential genetic signatures resulting from a NAb's interaction with a protein. While interactions between NAbs and HIV-1 Env are the emphasis, the Custom Input version can accomodate other types of data, including other proteins and organisms.

CATNAP

Purpose: Analyze our database of HIV-1 IC₅₀ and IC₈₀ neutralization data from publicly-available sources, in conjunction with HIV-1 Envelope sequences. Access our extensive databases of information about neutralizing antibodies and viruses used in published neutralization studies. Alignments of Env sequences for these viruses are also provided.

Help: CATNAP Help
Data: CATNAP data downloads

CATNAP: Custom Input

Purpose: Find potential genetic signatures based on your own numerical data in association with protein sequences. In addition to neutralization data, this tool is flexible enough to accomodate almost any kind of data in conjunction with almost any protein sequence.

Help: Custom CATNAP Help

CATNAP: Hybrid

Purpose: Compare and analyze your HIV-1 IC₅₀ and IC₈₀ neutralization data with published data. This tool will display your data side-by-side with data from our database of published HIV-1 neutralization data.

Help: Hybrid CATNAP Help

Reference

When using this tool in a publication, please cite:
Yoon et al. CATNAP: a tool to compile, analyze and tally neutralizing antibody panels. Nucleic Acid Res 2015 Jul 1;43(W1):W213-9. PMID 26044712.

The URL for citation is http://hiv.lanl.gov/catnap