Contents
Vol 2, Issue 7
Perspective
- Listening to each other: Infectious disease and cancer immunology
Shared immunological principles influence design of immunotherapies for both cancer and infectious diseases.
Focus
- Retrieving short-term memories of flu
Circulating TEM constantly seed the lung TRM pool after influenza infection. See the related Research Article by Slütter et al.
Research Articles
- Activation of mosquito complement antiplasmodial response requires cellular immunity
In malaria-infected mosquitoes, microvesicles from hemocytes activate complement to fight infection.
- Complement C5a receptor is the key initiator of neutrophil adhesion igniting immune complex–induced arthritis
C5aR directly initiates neutrophil adhesion required for immune complex–induced arthritis.
- Dynamics of influenza-induced lung-resident memory T cells underlie waning heterosubtypic immunity
Lung-resident memory T cell memory depends on reseeding from the circulating effector memory pool. See the Focus by Borges da Silva and Jameson.
- Tumor location determines tissue-specific recruitment of tumor-associated macrophages and antibody-dependent immunotherapy response
Tissue environment determines which immune effector cells contribute to tumor rejection by therapeutic antibodies.