01/12/2017
review
Perception is seen as a process that utilises partial and noisy information to construct a coherent understanding of the world. Tabor et al. argue that the experience of pain is no different; it is based on incomplete, multimodal information, which is used to estimate potential bodily threat. The authors outline a Bayesian inference model which highlights the statistical problems in everyday perception.
Image credit: WolfBlur/ pixabay.com
Current Issue December 2016
01/12/2017
research article
Controlled human malaria infection (CHMI) in healthy human volunteers is an important and powerful tool in clinical malaria vaccine development. Using their model, Coffeng et al. provide improved, robust power calculations for various hypothetical malaria vaccine trials, taking account of important sources of variation between and within individuals.
Image credit: Army Medicine/ Flickr
01/11/2017
methods paper
Complex brain networks are mainly estimated from empirical measurements. As a result, we obtain networks where everything is connected to everything else through different strengths of interaction. De Vico Fallani et al. propose a criterion to filter connectivity based on the optimization of fundamental properties of complex systems, i.e., efficiency and economy.
Image credit: De Vico Fallani et al.
01/09/2017
research article
To explain spikelet generation, Michalikova et al. propose a novel single-cell mechanism: somato-dendritic input generates action potentials at the axon initial segment that may fail to activate the soma and manifest as somatic spikelets.
Image credit: Mark Miller/ Flickr
01/06/2017
research article
Individual genes encode products that are diverse and optimal expression for each gene may differ. Rossi and Dunlop focus on how expression of diverse downstream genes is optimized by targets of the multiple antibiotic resistance activator MarA.
Image credit: Rossi, Dunlop.
01/05/2017
research article
Automatic image reconstruction is critical to cope with steadily increasing data from advanced microscopy. Kaltdorf et al. describe the Fiji macro 3D ART VeSElecT developed to study synaptic vesicles in electron tomograms.
Image credit: Kaltdorf et al.
01/11/2017
plos science wednesday
PLOS ONE authors Alasdair and Garrett discuss how they have divided the geography of the United States up by using data about millions of Americans' commuting habits.
Image credit: PLOS
06/19/2014
blast from the past
Image credit: Shiny Things/ Flickr
01/10/2017
in the news
Image credit: Kat Masback/ Flickr
01/12/2017
top tweet
Congrats to my friends in the @ButcherLab & @varnerlab on this new computational cell model of EMT in @PLOSCompBiol https://t.co/1Tfjtf6CRQ
Image credit: Twitter
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