The Operations, Management, and Information Division (OMI) serves as the focal point for the Northeast Fisheries Science Center's budget functions, labor relations, strategic planning, grants and acquisition, facility management, environmental compliance and safety, personal property, fleet vehicle management, and administrative processes.

OMI is responsible for the Center and Region public affairs, constituent affairs, media relations, technical editing and publishing, research libraries, and library services. Oversight of the Woods Hole Science Aquarium, a research and public display aquarium, also lies within this Division.