The activities of the groups listed contribute significantly to the Midwest DEWS.
- American Association of State Climatologists
- Environmental Protections Agency (EPA)
- FEMA
- National Weather Service
- Midwest Regional Climate Center
- National Drought Mitigation Center
- Northeast Climate Science Center
- Landscape Conservation Cooperatives
- USDA Midwest Climate Hub
- USDA Northern Forests Climate Hub
- USGS
- Army Corps of Engineers
- North Central Water Region Water Network
- Mississippi River Cities and Towns Initiative
- Upper Mississippi River Basin Association