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Stereoselective Synthesis, Docking, and Biological Evaluation of Difluoroindanediol-Based MenE Inhibitors as Antibiotics

Christopher E. Evans, Joe S. Matarlo, Peter J. Tonge*, and Derek S. Tan*

Chemical Synthesis of HMGA1a Proteins with Post-translational Modifications via Ser/Thr Ligation

Tianlu Li, Heng Liu, and Xuechen Li*

Co(I)-Mediated Removal of Addends on the C60 Cage and Formation of the Monovalent Cobalt Complex CpCo(CO)(η2-C60)

Yoshifumi Hashikawa, Michihisa Murata, Atsushi Wakamiya, and Yasujiro Murata*

Regioselective Copper-Catalyzed Boracarboxylation of Vinyl Arenes

Trevor W. Butcher, Edward J. McClain, Tyler G. Hamilton, Trina M. Perrone, Kayla M. Kroner, Gregory C. Donohoe, Novruz G. Akhmedov, Jeffrey L. Petersen, and Brian V. Popp*

Enantioselective Total Synthesis of (+)-Sieboldine A

Mohammed K. Abd El-Gaber, Shigeo Yasuda, Eisuke Iida, and Chisato Mukai*

    Articles ASAP (As Soon As Publishable)

    ASAP articles are edited and published online ahead of issue. See all ASAP articles.

    ZnBr2-Mediated Cascade Reaction of o-Alkoxy Alkynols: Synthesis of Indeno[1,2-c]chromenes

    Amol Milind Garkhedkar, Gopal Chandru SenadiJeh-Jeng Wang
    Publication Date (Web): January 25, 2017 (Letter)
    DOI: 10.1021/acs.orglett.6b03642
    Figure

    Biomimetic Synthesis and Structural Revision of Chaxine B and Its Analogues

    Yushi Hirata, Atsuo NakazakiHirokazu Kawagishi, Toshio Nishikawa
    Publication Date (Web): January 25, 2017 (Letter)
    DOI: 10.1021/acs.orglett.6b03724
    Figure

    Carbene-Catalyzed Reductive Coupling of Nitrobenzyl Bromide and Nitroalkene via the Single-Electron-Transfer (SET) Process and Formal 1,4-Addition

    Yuhuang Wang, Yu Du, Xuan Huang, Xingxing Wu, Yuexia Zhang, Song Yang, and Yonggui Robin Chi
    Publication Date (Web): January 25, 2017 (Letter)
    DOI: 10.1021/acs.orglett.6b03792
    Figure

    Suzuki–Miyaura Micellar Cross-Coupling in Water, at Room Temperature, and under Aerobic Atmosphere

    Sara Mattiello, Myles Rooney, Alessandro Sanzone, Paolo Brazzo, Mauro Sassi, and Luca Beverina
    Publication Date (Web): January 25, 2017 (Letter)
    DOI: 10.1021/acs.orglett.6b03817
    Figure

    Organocatalytic Asymmetric Michael/Hemiketalization/Retro-aldol Reaction of α-Nitroketones with Unsaturated Pyrazolones: Synthesis of 3-Acyloxy Pyrazoles

    Rajendra Maity, Chandan Gharui, Arun K. Sil, and Subhas Chandra Pan
    Publication Date (Web): January 25, 2017 (Letter)
    DOI: 10.1021/acs.orglett.6b03823
    Figure
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    Just Accepted manuscripts are peer-reviewed and accepted for publication. They are posted online prior to technical editing, formatting for publication and author proofing. See all Just Accepted Manuscripts.

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    The latest published issue of Organic Letters. See all articles.

    Skeletal Rearrangements of Polycyclic α-Ketols

    Moe Kawamura, Shogo Kamo, Shuhei Azuma, Konomi Kubo, Takahiro Sasamori, Norihiro Tokitoh, Kouji KuramochiKazunori Tsubaki
    Publication Date (Web): January 3, 2017 (Letter)
    DOI: 10.1021/acs.orglett.6b03541
    Figure

    Lewis Acid Catalyzed Diastereoselective Cycloaddition Reactions of Donor–Acceptor Cyclopropanes and Vinyl Azides: Synthesis of Functionalized Azidocyclopentane and Tetrahydropyridine Derivatives

    Raghunath Dey and Prabal Banerjee
    Publication Date (Web): January 3, 2017 (Letter)
    DOI: 10.1021/acs.orglett.6b03276
    Figure

    Pd-Catalyzed Intramolecular Aminoalkylation of Unactivated Alkenes: Access to Diverse N-Heterocycles

    Liu Ye, Kai-Yip Lo, Qiangshuai GuDan Yang
    Publication Date (Web): January 3, 2017 (Letter)
    DOI: 10.1021/acs.orglett.6b03295
    Figure

    Unified Approach to (Thio)chromenones via One-Pot Friedel–Crafts Acylation/Cyclization: Distinctive Mechanistic Pathways of β-Chlorovinyl Ketones

    Hun Young Kim, Eunsun Song, and Kyungsoo Oh
    Publication Date (Web): December 30, 2016 (Letter)
    DOI: 10.1021/acs.orglett.6b03348
    Figure

    Enantioselective Palladium-Catalyzed Oxidative Cascade Cyclization of Aliphatic Alkenyl Amides

    Wei Du, Qiangshuai Gu, Yang Li, Zhenyang LinDan Yang
    Publication Date (Web): January 9, 2017 (Letter)
    DOI: 10.1021/acs.orglett.6b03410
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    Most Read articles are refreshed daily and are based on full text downloads (PDF and HTML) from the previous 30 days and previous 12 months. Below is a Top 5 excerpt from the previous 30 days.

    Darwinolide, a New Diterpene Scaffold That Inhibits Methicillin-Resistant Staphylococcus aureus Biofilm from the Antarctic Sponge Dendrilla membranosa

    Jacqueline L. von Salm, Christopher G. Witowski, Renee M. Fleeman, James B. McClintock, Charles D. Amsler, Lindsey N. Shaw, and Bill J. Baker
    Publication Date (Web): May 13, 2016 (Letter)
    DOI: 10.1021/acs.orglett.6b00979
    Figure

    Synthesis of [18F]Arenes via the Copper-Mediated [18F]Fluorination of Boronic Acids

    Andrew V. Mossine, Allen F. Brooks, Katarina J. Makaravage, Jason M. Miller, Naoko Ichiishi, Melanie S. Sanford, and Peter J. H. Scott
    Publication Date (Web): November 14, 2015 (Letter)
    DOI: 10.1021/acs.orglett.5b02875
    Figure

    Enantioselective Total Synthesis of (+)-Sieboldine A

    Mohammed K. Abd El-Gaber, Shigeo Yasuda, Eisuke Iida, and Chisato Mukai
    Publication Date (Web): January 2, 2017 (Letter)
    DOI: 10.1021/acs.orglett.6b03416
    Figure

    Copper-Catalyzed Oxidative Cyclization of Carboxylic Acids

    Shyam SathyamoorthiJ. Du Bois
    Publication Date (Web): December 1, 2016 (Letter)
    DOI: 10.1021/acs.orglett.6b03176
    Figure

    Total Synthesis of (+)-Panacene

    Neanne Alnafta, Johannes P. Schmidt, Caroline L. Nesbitt, and Christopher S. P. McErlean
    Publication Date (Web): December 2, 2016 (Letter)
    DOI: 10.1021/acs.orglett.6b03219
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