2016 Regular Season NFL Leaders
| RK | PLAYER | PTS ADDED | PASS | RUN | PENALTY | TOTAL EPA | QB PLAYS | RAW QBR | TOTAL QBR |
| 1 | Tom Brady, NE | 34.9 | 39.9 | 3.3 | 1.1 | 48.4 | 258 | 87.1 | 86.1 |
| 2 | Dak Prescott, DAL | 56.1 | 61.1 | 13.4 | 2.0 | 83.2 | 417 | 87.0 | 85.8 |
| 3 | Matt Ryan, ATL | 41.2 | 53.5 | 4.4 | 1.3 | 69.9 | 414 | 80.3 | 81.1 |
| 4 | Drew Brees, NO | 34.2 | 57.3 | 1.5 | 1.0 | 66.8 | 474 | 73.5 | 74.8 |
| 5 | Kirk Cousins, WSH | 37.7 | 67.5 | -1.3 | 2.1 | 75.7 | 509 | 74.0 | 73.8 |
| 6 | Aaron Rodgers, GB | 38.2 | 41.2 | 14.1 | 5.6 | 69.8 | 501 | 74.6 | 73.3 |
| 7 | Matthew Stafford, DET | 30.0 | 41.2 | 11.4 | 3.4 | 65.6 | 474 | 71.0 | 72.0 |
| 8 | Andrew Luck, IND | 29.6 | 35.6 | 9.8 | 3.5 | 64.6 | 498 | 69.9 | 69.0 |
| 9 | Ben Roethlisberger, PIT | 23.7 | 38.0 | 1.9 | 1.4 | 47.3 | 426 | 68.8 | 68.0 |
| 10 | Philip Rivers, SD | 23.8 | 42.2 | 0.3 | 4.1 | 55.4 | 443 | 68.1 | 68.0 |
| RK | PLAYER | PTS ADDED | PASS | RUN | PENALTY | TOTAL EPA | QB PLAYS | RAW QBR | TOTAL QBR |
| 11 | Derek Carr, OAK | 22.2 | 45.8 | 2.0 | 5.9 | 57.6 | 464 | 66.3 | 67.2 |
| 12 | Tyrod Taylor, BUF | 18.0 | 20.7 | 14.4 | 1.6 | 45.8 | 405 | 65.2 | 66.4 |
| 13 | Russell Wilson, SEA | 18.1 | 41.3 | -2.3 | 2.3 | 50.6 | 420 | 64.8 | 66.1 |
| 14 | Jameis Winston, TB | 22.4 | 42.5 | 3.3 | -1.6 | 52.8 | 467 | 66.3 | 66.1 |
| 15 | Marcus Mariota, TEN | 19.6 | 36.1 | 3.0 | 4.1 | 50.7 | 459 | 64.7 | 64.5 |
| 16 | Blaine Gabbert, SF | 6.6 | 7.6 | 6.7 | 0.5 | 17.6 | 206 | 61.2 | 63.5 |
| 17 | Brian Hoyer, CHI | 9.9 | 22.9 | -0.4 | -0.2 | 23.9 | 224 | 65.2 | 61.7 |
| 18 | Alex Smith, KC | 9.0 | 23.9 | 2.3 | 0.3 | 31.7 | 367 | 58.6 | 61.4 |
| 19 | Cam Newton, CAR | 13.9 | 18.6 | 6.6 | 3.9 | 41.6 | 416 | 61.6 | 61.0 |
| 20 | Eli Manning, NYG | 14.8 | 40.3 | 0.4 | 1.8 | 48.2 | 427 | 62.0 | 58.4 |
| RK | PLAYER | PTS ADDED | PASS | RUN | PENALTY | TOTAL EPA | QB PLAYS | RAW QBR | TOTAL QBR |
| 21 | Trevor Siemian, DEN | 7.9 | 23.2 | -0.9 | 3.2 | 34.0 | 353 | 57.8 | 57.5 |
| 22 | Andy Dalton, CIN | 8.1 | 23.5 | 4.7 | 2.6 | 40.4 | 454 | 56.3 | 57.0 |
| 23 | Sam Bradford, MIN | 10.2 | 24.7 | -0.1 | 2.1 | 38.5 | 407 | 58.8 | 56.1 |
| 24 | Carson Palmer, ARI | 7.9 | 20.1 | 2.2 | 3.5 | 37.6 | 437 | 56.4 | 56.0 |
| 25 | Colin Kaepernick, SF | 3.7 | -1.2 | 13.1 | 0.0 | 18.2 | 221 | 56.0 | 55.7 |
| 26 | Ryan Tannehill, MIA | 5.0 | 17.8 | 3.8 | 0.7 | 31.0 | 362 | 54.8 | 54.6 |
| 27 | Brock Osweiler, HOU | 6.9 | 17.3 | 6.6 | 2.7 | 34.5 | 410 | 55.9 | 54.4 |
| 28 | Joe Flacco, BAL | 7.7 | 30.8 | 3.7 | 1.0 | 45.0 | 475 | 55.7 | 53.8 |
| 29 | Cody Kessler, CLE | -0.2 | 11.0 | -2.4 | 0.9 | 17.6 | 243 | 49.8 | 50.5 |
| 30 | Blake Bortles, JAX | 2.3 | 22.4 | 1.9 | 3.2 | 35.3 | 508 | 51.6 | 49.9 |
| RK | PLAYER | PTS ADDED | PASS | RUN | PENALTY | TOTAL EPA | QB PLAYS | RAW QBR | TOTAL QBR |
| 31 | Ryan Fitzpatrick, NYJ | -6.5 | 7.0 | 4.8 | 3.2 | 21.6 | 364 | 43.7 | 45.7 |
| 32 | Carson Wentz, PHI | -4.8 | 27.7 | -7.4 | 0.8 | 29.1 | 439 | 46.1 | 45.1 |
| 33 | Case Keenum, LA | -7.5 | 10.2 | 0.1 | 1.2 | 22.5 | 378 | 43.0 | 44.3 |