4-Methylphenol
CASRN 106-44-5
- IRIS Summary (PDF) (13 pp, 114 K)
- Status: 4-Methylphenol is not being reassessed by IRIS at this time.
Health Hazard Assessments for Effects Other than Cancer
Reference Dose for Oral Exposure (RfD) (PDF) (13 pp, 114 K)
last updated: 08/01/1991
Information reviewed but value not estimated.
Reference Concentration for Inhalation Exposure (RfC) (PDF) (13 pp, 114 K)
last updated: 04/01/1992
Information reviewed but value not estimated.
Cancer Assessment
Weight of Evidence for Cancer (PDF) (13 pp, 114 K)
last updated: 09/01/1990
| WOE Characterization | Framework for WOE Characterization |
|---|---|
| C (Possible human carcinogen) | Guidelines for Carcinogen Risk Assessment (US EPA, 1986) |
- Based on an increased incidence of skin papillomas in mice in an initiation-promotion study. The three cresol isomers produced positive results in genetic toxicity studies both alone and in combination.
- This may be a synopsis of the full weight-of-evidence narrative.
Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (13 pp, 114 K)
Not assessed under the IRIS Program.
Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (13 pp, 114 K)
Not assessed under the IRIS Program.
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Chemical Structure for
4-Methylphenol
