Nickel carbonyl
CASRN 13463-39-3
- IRIS Summary (PDF) (7 pp, 88 K)
- Status: Nickel carbonyl is not being reassessed by IRIS at this time.
Health Hazard Assessments for Effects Other than Cancer
Reference Dose for Oral Exposure (RfD) (PDF) (7 pp, 88 K)
Not assessed under the IRIS Program.
Reference Concentration for Inhalation Exposure (RfC) (PDF) (7 pp, 88 K)
Not assessed under the IRIS Program.
Cancer Assessment
Weight of Evidence for Cancer (PDF) (7 pp, 88 K)
last updated: 09/30/1987
| WOE Characterization | Framework for WOE Characterization |
|---|---|
| B2 (Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals) | Guidelines for Carcinogen Risk Assessment (US EPA, 1986) |
- Based upon the observation of pulmonary carcinomas and malignant tumors at various sites in rats administered nickel carbonyl by inhalation and intravenous injection, respectively. Nickel administered as nickel carbonyl binds to DNA.
- This may be a synopsis of the full weight-of-evidence narrative.
Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (7 pp, 88 K)
Not assessed under the IRIS Program.
Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (7 pp, 88 K)
Not assessed under the IRIS Program.
You will need Adobe Reader to view some of the files on this page. See EPA’s PDF page to learn more.
Chemical Structure for
Nickel carbonyl
