Chloral hydrate
CASRN 302-17-0
- Toxicological Review (PDF) (69 pp, 148 K)
- IRIS Summary (PDF) (39 pp, 220 K)
- Status: Chloral hydrate is not being reassessed by IRIS at this time.
Health Hazard Assessments for Effects Other than Cancer
Reference Dose for Oral Exposure (RfD) (PDF) (39 pp, 220 K)
last updated: 09/15/2000
|
Reference Concentration for Inhalation Exposure (RfC) (PDF) (39 pp, 220 K)
last updated: 09/15/2000
Not assessed under the IRIS Program.
Cancer Assessment
Weight of Evidence for Cancer (PDF) (39 pp, 220 K)
last updated: 09/15/2000
| WOE Characterization | Framework for WOE Characterization |
|---|---|
| C (Possible human carcinogen) | Guidelines for Carcinogen Risk Assessment (US EPA, 1986) |
| Carcinogenic potential cannot be determined (Oral route) | Proposed Guidelines for Carcinogen Risk Assessment (US EPA, 1996) |
- Under the 1986 cancer guidelines (U.S. EPA, 1986), chloral hydrate is assigned to Group C, possible human carcinogen. Under the 1996 proposed guidelines for carcinogen risk assessment (U.S. EPA, 1996), chloral hydrate shows suggestive evidence of human carcinogenicity by the oral route of exposure. There are no carcinogenicity data from humans.
- This may be a synopsis of the full weight-of-evidence narrative.
Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (39 pp, 220 K)
Not assessed under the IRIS Program.
Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (39 pp, 220 K)
Not assessed under the IRIS Program.
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Critical Effect Systems
Chemical Structure for
Chloral hydrate
