Indicator	Year(s) Covered	Geographic Area Covered	Theme Area(s) and Question(s) the Indicator Helps Address	Related Conceptual Diagrams
Acid Deposition	1989 - 2013	Contiguous 48 states	Air: What are the trends in outdoor air quality and their effects on human health and the environment?	Acid Deposition Coastal Hypoxia Nutrient Impacts
Acidity in Lakes and Streams	1991 - 2012	Selected acid-sensitive regions	Water: What are the trends in the extent and condition of fresh surface waters and their effects on human health and the environment? Air: What are the trends in outdoor air quality and their effects on human health and the environment? Ecological Condition: What are the trends in the critical physical and chemical attributes of the nation's ecological systems?	Acid Deposition
Agricultural Fertilizer	1960 - 2011	United States	Land: What are the trends in chemicals used on land and their effects on human health and the environment?
Air Toxics Concentrations	2003 - 2013	United States	Air: What are the trends in outdoor air quality and their effects on human health and the environment?
Air Toxics Emissions	1990 - 2011	United States	Air: What are the trends in outdoor air quality and their effects on human health and the environment?
Asthma	1980 - 2014	United States	Human Exposure and Health: What are the trends in human disease and conditions for which environmental contaminants may be a risk factor?	Tropospheric Ozone
Benthic Macroinvertebrates in Wadeable Streams	2000 - 2009	Contiguous 48 states	Water: What are the trends in the extent and condition of fresh surface waters and their effects on human health and the environment? Ecological Condition: What are the trends in the diversity and biological balance of the nation's ecological systems?	Acid Deposition Nutrient Impacts Wetland Loss
Bird Populations	1966 - 2011	Contiguous 48 states, southern Canada, and southeastern Alaska	Ecological Condition: What are the trends in the diversity and biological balance of the nation's ecological systems?	Wetland Loss
Birth Defects	1999 - 2013	United States	Human Exposure and Health: What are the trends in human disease and conditions for which environmental contaminants may be a risk factor?
Blood Cadmium	1999 - 2012	United States	Human Exposure and Health: What are the trends in human exposure to environmental contaminants?
Blood Lead	1999 - 2012	United States	Human Exposure and Health: What are the trends in human exposure to environmental contaminants?
Blood Mercury	1999 - 2012	United States	Human Exposure and Health: What are the trends in human exposure to environmental contaminants?	Fish Mercury Contamination
Cancer	1973 - 2012	United States	Human Exposure and Health: What are the trends in human disease and conditions for which environmental contaminants may be a risk factor?
Carbon Monoxide Concentrations	1980 - 2013	United States	Air: What are the trends in outdoor air quality and their effects on human health and the environment?
Carbon Monoxide Emissions	1990 - 2011	United States	Air: What are the trends in outdoor air quality and their effects on human health and the environment?
Carbon Storage in Forests	1990 - 2013	Contiguous 48 states and southern Alaska	Ecological Condition: What are the trends in the ecological processes that sustain the nation's ecological systems?
Cardiovascular Disease	1979 - 2014	United States	Human Exposure and Health: What are the trends in human disease and conditions for which environmental contaminants may be a risk factor?
Childhood Cancer	1973 - 2012	United States	Human Exposure and Health: What are the trends in human disease and conditions for which environmental contaminants may be a risk factor?
Chronic Obstructive Pulmonary Disease	1979 - 2012	United States	Human Exposure and Health: What are the trends in human disease and conditions for which environmental contaminants may be a risk factor?	Tropospheric Ozone
Coastal Benthic Communities	1999 - 2006	Coastal waters of the contiguous 48 states and selected territories	Ecological Condition: What are the trends in the diversity and biological balance of the nation's ecological systems? Water: What are the trends in the extent and condition of coastal waters and their effects on human health and the environment?	Coastal Hypoxia Nutrient Impacts Wetland Loss
Coastal Fish Tissue	2003 - 2006	Coastal waters of the contiguous 48 states, Alaska, and selected territories	Water: What are the trends in the extent and condition of coastal waters and their effects on human health and the environment? Ecological Condition: What are the trends in biomarkers of exposure to common environmental contaminants in plants and animals? Water: What are the trends in the condition of consumable fish and shellfish and their effects on human health?	Fish Mercury Contamination
Coastal Sediment Quality	1999 - 2006	Coastal waters of the contiguous 48 states, Alaska, Hawaii, and selected territories	Water: What are the trends in the extent and condition of coastal waters and their effects on human health and the environment?	Fish Mercury Contamination
Contaminated Ground Water Migration at Cleanup Sites	2000 - 2015	United States	Land: What are the trends in contaminated land and their effects on human health and the environment?
Drinking Water	1993 - 2015	United States	Water: What are the trends in the quality of drinking water and their effects on human health?
Ecological Connectivity	2001	Contiguous 48 states	Ecological Condition: What are the trends in the extent and distribution of the nation's ecological systems?
Energy Use	1949 - 2014	United States	Air: What are the trends in outdoor air quality and their effects on human health and the environment? Air: What are the trends in greenhouse gas emissions and concentrations and their impacts on human health and the environment?	Acid Deposition Coastal Hypoxia Fish Mercury Contamination Nutrient Impacts Tropospheric Ozone
Fish Faunal Intactness	Historical - 2014	Contiguous 48 states	Ecological Condition: What are the trends in the diversity and biological balance of the nation's ecological systems?	Acid Deposition Coastal Hypoxia Nutrient Impacts Wetland Loss
Forest Extent and Type	1907 - 2012	United States	Ecological Condition: What are the trends in the extent and distribution of the nation's ecological systems? Land: What are the trends in land cover and their effects on human health and the environment?
Forest Fragmentation	2001 - 2011	Contiguous 48 states	Ecological Condition: What are the trends in the extent and distribution of the nation's ecological systems?
Freshwater Withdrawals	1950 - 2010	United States	Water: What are the trends in the extent and condition of fresh surface waters and their effects on human health and the environment? Water: What are the trends in the extent and condition of ground water and their effects on human health and the environment?	Wetland Loss
General Mortality	1940 - 2013	United States	Human Exposure and Health: What are the trends in health status in the United States?
Greenhouse Gas Concentrations	800,000 BC - 2014 AD	Global	Air: What are the trends in greenhouse gas emissions and concentrations and their impacts on human health and the environment?
Hazardous Waste	2001 - 2011	United States	Land: What are the trends in wastes and their effects on human health and the environment?
Human Exposures at Cleanup Sites	2000 - 2015	United States	Land: What are the trends in contaminated land and their effects on human health and the environment?
Hypoxia in Gulf of Mexico and Long Island Sound	1985 - 2014	Northern Gulf of Mexico and Long Island Sound	Water: What are the trends in the extent and condition of coastal waters and their effects on human health and the environment? Ecological Condition: What are the trends in the critical physical and chemical attributes of the nation's ecological systems?	Coastal Hypoxia Nutrient Impacts
Infant Mortality	1940 - 2013	United States	Human Exposure and Health: What are the trends in health status in the United States?
Infectious Diseases	1995 - 2013	United States	Human Exposure and Health: What are the trends in human disease and conditions for which environmental contaminants may be a risk factor?
Lake Fish Tissue	2000 - 2003	Contiguous 48 states	Ecological Condition: What are the trends in biomarkers of exposure to common environmental contaminants in plants and animals? Water: What are the trends in the condition of consumable fish and shellfish and their effects on human health?	Fish Mercury Contamination
Land Cover	2001 - 2011	Contiguous 48 states	Ecological Condition: What are the trends in the extent and distribution of the nation's ecological systems? Land: What are the trends in land cover and their effects on human health and the environment?	Nutrient Impacts Wetland Loss
Land Use	1977 - 2007	United States	Ecological Condition: What are the trends in the extent and distribution of the nation's ecological systems? Land: What are the trends in land use and their effects on human health and the environment?	Wetland Loss
Lead Concentrations	1980 - 2013	United States	Air: What are the trends in outdoor air quality and their effects on human health and the environment?
Lead Emissions	1970 - 2011	United States	Air: What are the trends in outdoor air quality and their effects on human health and the environment?
Life Expectancy	1940 - 2013	United States	Human Exposure and Health: What are the trends in health status in the United States?
Low Birthweight	1995 - 2014	United States	Human Exposure and Health: What are the trends in human disease and conditions for which environmental contaminants may be a risk factor?
Manganese Concentrations in Region 5	2000 - 2013	EPA Region 5 (Great Lakes region)	Air: What are the trends in outdoor air quality and their effects on human health and the environment?
Mercury Emissions	1990 - 2011	United States	Air: What are the trends in outdoor air quality and their effects on human health and the environment?	Fish Mercury Contamination
Municipal Solid Waste	1960 - 2013	United States	Land: What are the trends in wastes and their effects on human health and the environment?
Nitrate and Pesticides in Ground Water	1992 - 2003	Contiguous 48 states	Water: What are the trends in the extent and condition of ground water and their effects on human health and the environment?	Nutrient Impacts
Nitrogen Dioxide Concentrations	1980 - 2013	United States	Air: What are the trends in outdoor air quality and their effects on human health and the environment?	Acid Deposition Coastal Hypoxia Nutrient Impacts Tropospheric Ozone
Nitrogen Oxides Emissions	1990 - 2011	United States	Air: What are the trends in outdoor air quality and their effects on human health and the environment?	Acid Deposition Coastal Hypoxia Nutrient Impacts Tropospheric Ozone
Nitrogen and Phosphorus in Agricultural Streams	1992 - 2001	Contiguous 48 states	Water: What are the trends in the extent and condition of fresh surface waters and their effects on human health and the environment? Ecological Condition: What are the trends in the critical physical and chemical attributes of the nation's ecological systems?	Coastal Hypoxia Nutrient Impacts Wetland Loss
Nitrogen and Phosphorus in Large Rivers	1955 - 2014	Four large river basins	Water: What are the trends in the extent and condition of fresh surface waters and their effects on human health and the environment? Ecological Condition: What are the trends in the critical physical and chemical attributes of the nation's ecological systems?	Coastal Hypoxia Nutrient Impacts Wetland Loss
Nitrogen and Phosphorus in Wadeable Streams	2000 - 2009	Contiguous 48 states	Water: What are the trends in the extent and condition of fresh surface waters and their effects on human health and the environment? Ecological Condition: What are the trends in the critical physical and chemical attributes of the nation's ecological systems?	Coastal Hypoxia Nutrient Impacts Wetland Loss
Non-Indigenous Estuarine Species in Pacific Northwest	1999 - 2001	Pacific Northwest	Ecological Condition: What are the trends in the diversity and biological balance of the nation's ecological systems?
Ozone Concentrations	1978 - 2013	United States	Air: What are the trends in outdoor air quality and their effects on human health and the environment?	Tropospheric Ozone
Ozone Injury to Forest Plants	2006	United States	Air: What are the trends in outdoor air quality and their effects on human health and the environment? Ecological Condition: What are the trends in biomarkers of exposure to common environmental contaminants in plants and animals?	Tropospheric Ozone
Ozone and Particulate Matter Concentrations Along U.S./Mexico Border	1986 - 2013	U.S./Mexico border region	Air: What are the trends in outdoor air quality and their effects on human health and the environment?	Tropospheric Ozone
Ozone-Depleting Substances Concentrations	1992 - 2013	Global	Air: What are the trends in outdoor air quality and their effects on human health and the environment?
Particulate Matter Concentrations	1988 - 2013	United States	Air: What are the trends in outdoor air quality and their effects on human health and the environment?
Particulate Matter Emissions	1990 - 2011	United States	Air: What are the trends in outdoor air quality and their effects on human health and the environment?
Pesticide Incidents	1998 - 2014	United States	Land: What are the trends in chemicals used on land and their effects on human health and the environment?
Pesticide Residues in Food	1994 - 2014	United States	Land: What are the trends in chemicals used on land and their effects on human health and the environment?
Pesticides in Agricultural Streams	1992 - 2001	Contiguous 48 states	Water: What are the trends in the extent and condition of fresh surface waters and their effects on human health and the environment?	Wetland Loss
Preterm Delivery	1995 - 2014	United States	Human Exposure and Health: What are the trends in human disease and conditions for which environmental contaminants may be a risk factor?
Radon: Homes At or Above EPA's Action Level	1990 - 2013	United States	Air: What are the trends in indoor air quality and their effects on human health?
Regional Haze	1992 - 2013	Contiguous 48 states	Air: What are the trends in outdoor air quality and their effects on human health and the environment?
Sea Level	1880 - 2016	Global	Air: What are the trends in greenhouse gas emissions and concentrations and their impacts on human health and the environment? Ecological Condition: What are the trends in the critical physical and chemical attributes of the nation's ecological systems?	Wetland Loss
Sea Surface Temperature	1880 - 2015	Global	Air: What are the trends in greenhouse gas emissions and concentrations and their impacts on human health and the environment? Ecological Condition: What are the trends in the critical physical and chemical attributes of the nation's ecological systems?
Serum Cotinine	1988 - 2012	United States	Human Exposure and Health: What are the trends in human exposure to environmental contaminants? Air: What are the trends in indoor air quality and their effects on human health?
Serum Persistent Organic Pollutants	1999 - 2004	United States	Human Exposure and Health: What are the trends in human exposure to environmental contaminants?
Stratospheric Ozone Levels	1964 - 2012	North America	Air: What are the trends in outdoor air quality and their effects on human health and the environment?
Stream Flows	1961 - 2015	Contiguous 48 states	Water: What are the trends in the extent and condition of fresh surface waters and their effects on human health and the environment? Ecological Condition: What are the trends in the critical physical and chemical attributes of the nation's ecological systems?	Wetland Loss
Streambed Stability	2008 - 2009	Contiguous 48 states	Water: What are the trends in the extent and condition of fresh surface waters and their effects on human health and the environment? Ecological Condition: What are the trends in the critical physical and chemical attributes of the nation's ecological systems?	Wetland Loss
Submerged Aquatic Vegetation in Chesapeake Bay	1978 - 2015	Chesapeake Bay	Ecological Condition: What are the trends in the diversity and biological balance of the nation's ecological systems? Water: What are the trends in the extent and condition of coastal waters and their effects on human health and the environment?	Nutrient Impacts
Sulfur Dioxide Concentrations	1978 - 2013	United States	Air: What are the trends in outdoor air quality and their effects on human health and the environment?	Acid Deposition
Sulfur Dioxide Emissions	1990 - 2011	United States	Air: What are the trends in outdoor air quality and their effects on human health and the environment?	Acid Deposition
Temperature and Precipitation	1901 - 2015	Global	Air: What are the trends in greenhouse gas emissions and concentrations and their impacts on human health and the environment? Ecological Condition: What are the trends in the critical physical and chemical attributes of the nation's ecological systems?	Wetland Loss
Toxic Chemicals in Wastes	2001 - 2012	United States	Land: What are the trends in chemicals used on land and their effects on human health and the environment?
Trophic State of Coastal Waters	1999 - 2006	Coastal waters of the contiguous 48 states, Alaska, Hawaii, and selected territories	Water: What are the trends in the extent and condition of coastal waters and their effects on human health and the environment?	Coastal Hypoxia Nutrient Impacts
U.S. Greenhouse Gas Emissions	1990 - 2013	United States	Air: What are the trends in greenhouse gas emissions and concentrations and their impacts on human health and the environment?
Urbanization and Population Change	1790 - 2012	United States	Ecological Condition: What are the trends in the extent and distribution of the nation's ecological systems? Land: What are the trends in land use and their effects on human health and the environment?	Wetland Loss
Urinary Pesticides	1999 - 2008	United States	Human Exposure and Health: What are the trends in human exposure to environmental contaminants?
Urinary Phthalates	1999 - 2012	United States	Human Exposure and Health: What are the trends in human exposure to environmental contaminants?
Volatile Organic Compounds Emissions	1990 - 2011	United States	Air: What are the trends in outdoor air quality and their effects on human health and the environment?	Tropospheric Ozone
Wetlands	1954 - 2009	Contiguous 48 states	Ecological Condition: What are the trends in the extent and distribution of the nation's ecological systems? Water: What are the trends in the extent and condition of wetlands and their effects on human health and the environment? Water: What are the trends in the extent and condition of coastal waters and their effects on human health and the environment?	Wetland Loss

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