NMR and EPR
Molecular systems important to biology, environmental remediation and sustainability are studied using a suite of nuclear magnetic resonance (NMR) spectrometers with frequencies ranging from 300 to 850 MHz. A pair of electron paramagnetic resonance (EPR) spectrometers complement the capability. See a complete list of NMR and EPR instruments.
Science Theme:
Molecular systems important to biology, environmental remediation and sustainability are studied using a suite of nuclear magnetic resonance (NMR) spectrometers with frequencies ranging from 300 to 850 MHz. A pair of electron paramagnetic resonance (EPR) spectrometers complement the capability. See a complete list of NMR and EPR instruments.
Seattle Structural Genomics Center for Infectious Disease (SSGCID) -- Year X
Hydrogen Uptake and Release in Condensed Phases
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Integration of Substrate Oxidation with Protein Synthesis and Cellular Signaling in a Complex Biological System
EMSL's annual call for proposals opens in early January
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Deciphering Microbial Communication Through Metabolites
Deep down fracking wells, microbial communities thrive
Pages
Description
Interfacial and in situ biology—Innovative NMR instrumentation and techniques for probing properties of macromolecular cellular assemblies and in situ and ex situ metabolic processes, as well as for exploring biological membrane proteins in the solid state. Unique EPR and variable-temperature NMR approaches to explore structure and properties of redox metal centers cell biology.
Environmental chemistry— EMSL offers a unique NMR system for radiological studies. Users can perform magic angle spinning of highly radioactive samples with a novel hermetically sealed 3.2mm NMR probe. These tools allow users to apply NMR techniques to critical areas of radiological research, including the study of radioactive waste processing and storage.
Interfacial and in situ chemistry—Leading-edge solid-state NMR probe technology to analyze and quantify properties of advanced energy materials, fuel cells and real-time catalytic processes. High power pulsed field gradient diffusion capabilities for liquid and solid samples.
EMSL offers unique and custom NMR and EPR tools, including probes for specialized studies.
- NMR spectrometers, ranging from 300 MHz to 850 MHz for high-field liquid-state, solid-state and micro-imaging techniques
- W- and X-band pulsed EPR spectremeter for probing metal centers in biological and materials systems
- NMR metabolomics capabilities
- Extreme-temperature probes, both high and low temperatures
- Virtual NMR tools for remote access to spectrometer systems.
Instruments
Highlighted Research Applications
Characterization of natural and soil organic matter (NOM and SOM)
CO2 sequestration investigations via high-...
Custodian(s): Sarah D Burton, David Hoyt
Research Applications
Characterization of quadrupolar nuclei for inorganic and biological materials and natural sediments
Cryogenic NMR capabilities...
Custodian(s): Nancy Washton, Andrew S Lipton
Highlighted Research Applications
EMSL's Bruker 500-MHz WB spectrometer is uniquely tailored for in vivo studies:
Microbial biofilms relevant to...
Type of Instrument:
Nuclear Magnetic Resonance Spectrometer (NMR)
Research Applications
Dynamics studies via 2H NMR
Characterization of quadrupolar nuclei for materials and biological samples
Characterization of...
Custodian(s): Andrew S Lipton, Sarah D Burton
Highlighted Research Applications
Structural biology
Protein structure and dynamics
Nuclei acid structure and dynamics.
Metabolomics
Eukaryotic and...
Custodian(s): Nancy Isern, David Hoyt
Publications
For the first time, the use of an argon cluster ion sputtering source has been demonstrated to perform superiorly relative to traditional oxygen and...
Using a deuterated sample, all the observable backbone 1HN, 15N, 13Cα, and 13C´ chemical shifts for the dimeric, periplasmic...
Solid-state transport and electrochemical properties of Ti-doped hematite (001) epitaxial thin films (6.0, 8.3, and 16.6 at% Ti) were probed to...
We present classical molecular simulations of the adsorption free energy profiles for the aqueous Fe(II) ion approaching key low index crystal faces...
Crimean-Congo Hemorrhagic fever virus (CCHFV) is one of several lethal viruses that encodes for a viral ovarian tumor domain (vOTU), which serves to...
Science Highlights
Posted: November 28, 2016
Tom Rickey, PNNL
Genetics and birthplace have a big effect on the make-up of the microbial community in the gut, according to research published Nov...
Posted: September 22, 2016
Plutonium is a highly complex element. Scientists at Pacific Northwest National Laboratory and Washington State University used RadEMSL, EMSL’s...
Posted: September 14, 2016
The Science
Peptides are naturally occurring molecules with excellent pharmaceutical properties, but their therapeutic use has been limited by the...
Posted: September 06, 2016
The Science
Hydraulic fracturing (“fracking”) is the industry standard for extracting hydrocarbons from shale formations, which provide one-third of...
Posted: May 27, 2016
The Science
The ability of plants and microorganisms to take up organic nitrogen in the form of amino acids and peptides has received increasing...
Instruments
Lignin obtained from lignocellulosic biomass is an abundant, renewable, low-cost resource whose carbon-rich, aromatic composition makes it ideal to...
This is a proposal to use advanced solid-state NMR methods to elucidate the architecture and arrangement of cell walls of plants, grass species in...
This proposal aims to provide molecular insight into elementary reaction steps and their kinetics in condensed phases at an atomic and molecular...
A critical step in the lignocellulosic biofuels pipeline is the extraction of fermentable sugars from plant biomass. Extracellular fungal enzymes are...
The Joint Center for Energy Storage Research (JCESR) is performing transformational research to overcome critical scientific and technical barriers...
Leads
(509) 371-7094
Dr. Washton is the capability lead for NMR and EPR, and provides scientific and technical expertise and leadership in support of EMSL’s user program, strategy and scientific productivity. Washton works on coupling NMR with computational...