Synthetic Biology

Proposals to the Biological Control program (DARPA-BAA-16-17) are due April 29, 2016. The program seeks to build the foundations for multiscale control of biological systems.

From programmable microbes to human-machine symbiosis, biological technologies are expanding our definition of technology and redefining how we interact with and use biology.

“Biology is nature’s ultimate innovator, and any agency that hangs its hat on innovation would be foolish not to look to this master of networked complexity for inspiration and solutions.” – DARPA Director Arati Prabhakar, Testimony to Subcommittee on Intelligence, Emerging Threats and Capabilities, U.S. House of Representatives, March 26, 2014

The development of increasingly sophisticated techniques and tools to sequence, synthesize and manipulate genetic material has led to the rapidly maturing discipline of synthetic biology. To date, work in synthetic biology has focused primarily on manipulating individual species of domesticated organisms to perform specific tasks, such as producing medicines or fuels.

The structural materials that are currently used to construct homes, buildings, and infrastructure are expensive to produce and transport, wear out due to age and damage, and have limited ability to respond to changes in their immediate surroundings. Living biological materials—bone, skin, bark, and coral, for example—have attributes that provide advantages over the non-living materials people build with, in that they can be grown where needed, self-repair when damaged, and respond to changes in their surroundings.