49 CFR Part 199 (PHMSA drug and alcohol testing regulation) and 49 CFR Part 40 (DOT drug and alcohol testing regulation) require operators to conduct drug and alcohol testing of covered employees who perform operation, maintenance, or emergency-response functions regulated by 49 CFR Parts 192, 193, or 195.

In accordance with 49 CFR 199.119 and 49 CFR 199.229, pipeline operators subject to 49 CFR part 199 regulations with more than 50 covered employees are required to submit an MIS report annually. Small operators (50 or fewer covered employees) subject to 49 CFR 199 are required to submit an MIS report only upon PHMSA's written notice.

MIS Reporting Guidance

Federal Register Notice - CY 2014 Random Drug Rate, Contractor Reporting, and DAMIS UN/PW