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Summary of Parker, et al. (2008) Perchlorate in groundwater: [20 KB]: Parker, et al. (2008) Perchlorate in groundwater: A synoptic survey of pristine sites in the contiguous United States. Environ. Sci. Technol.
42(5): 1465-1471. Authors used a network of volunteers to collect 326 groundwater samples, avoiding areas of EAP-documented use or release. Of the 326 samples, 147 (45%) were below the method detection limit (40 ng/L), 42 (13%) were between the MDL and the method reporting limit (120 ng/L). Of the 137 samples that could be quantified, most (109) contained less than 1000 ng/L of perchlorate; the remaining 28 contained from 1000-10,400 ng/L. Perchlorate concentrations were positively-correlated with nitrate levels, but not with chloride concentrations.

DoD Request for Extension [85 KB]: Historical correspondence within DoD and between DoD and other federal agencies and states related to perchlorate.

Summary of Tran, et al. 2008 article on active transport of perchlorate into t [20 KB]: Tran, N., et al. (2008) Thyroid stimulating hormone increases active transport of perchlorate into thyroid cells. Am J. Physiol Endocrinol. Metab., 26 Feb 2008 (e-pub ahead of publication). Using an in vitro system, authors found that perchlorate is actively transported into thyroid cells, and this transport increases in a dose-related manner when treated with TSH. Addition of iodine appeared to competitively-inhibit perchlorate transport. The highest concentration of perchlorate, 100 micromole/L, did not inhibit cell proliferation over a 72 hour period.