Alternate Drivers and Random Testing: Can an alternate driver be selected for a DOT random test if the driver originally selected is not able to be tested during the selection period?

Yes, however, the selection of an alternate driver for random testing is only permissible if the primary driver selected will not be available for testing for the entire selection period because of long-term absence due to layoff, illness, injury, vacation or other circumstances.  Please see [§382.305, Question 18.