Compendium of Evidence-Based Interventions and Best Practices for HIV Prevention
The Evidence-Based Interventions (EBIs) and Best Practices in the Compendium are identified by the CDC’s Prevention Research Synthesis (PRS) Project through a series of ongoing systematic reviews. Each eligible intervention is evaluated against explicit a priori criteria (PrEP criteria; SI criteria; LRC criteria; MA criteria; RR criteria) and has shown sufficient evidence that the intervention works. The PRS Project will regularly update this Compendium as new EBIs and Best Practices are identified. Additional details about the Compendium or the PRS Project can be obtained by contacting PRS.
- Shown to have significant effects in HIV-related outcomes
- Tested with a comparison group
EBIs work, are rigorously evaluated and provide the strongest evidence of efficacy.
- Shown to have significant effects in HIV-related outcomes
- Tested with a weaker design or fewer participants
EIs have some evidence of working and need further testing.
The Compendium comprises five chapters. A complete listing of each chapter can be accessed below.
- The NEW Pre-Exposure Prophylaxis (PrEP) Chapter of the Compendium includes 3 best practices. (Updated July 14, 2020)
- The Structural Interventions (SI) Chapter of the Compendium includes 38 best practices. (Updated November 27, 2020)
- The Linkage to, Retention in, and Re-engagement in HIV Care (LRC) Chapter of the Compendium includes 31 best practices. ( Updated August 12, 2020)
- The Medication Adherence (MA) Chapter of the Compendium includes 19 EBIs. (Updated November 22, 2019)
- The Risk Reduction (RR) Chapter of the Compendium includes 59 behavioral EBIs. (Updated June 19, 2020)
Our recommendation on how to cite the PRS Compendium:
HIV/AIDS Prevention Research Synthesis Project. Compendium of Evidence-Based Interventions and Best Practices for HIV Prevention. Centers for Disease Control and Prevention. https://www.cdc.gov/hiv/research/interventionresearch/compendium/index.html. Date last updated. Date Accessed.