The United States established diplomatic relations with Republic of the Congo in 1960, following the country's independence from France. Diplomatic relations were suspended in 1965, then resumed in 1977. In 1992, Republic of the Congo completed a transition to multiparty democracy; the country saw several years of civil conflict during 1997-2003.

U.S.-Republic of the Congo relations are positive and cooperative. The two countries have worked together on issues such as strengthening regional security, improving the health of Congolese citizens, and safeguarding the environment. The United States has supported Congolese democratization efforts, contributing aid to the country's electoral process and working alongside Congolese civil society and private sector leaders as well as government officials to improve human rights and help build a more stable, secure, democratic, and prosperous Congo.