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RCDC

Estimates of Funding for Various Research, Condition, and Disease Categories (RCDC)


Table Published: March 7, 2014

The table below displays the annual support level for various research, condition, and disease categories based on grants, contracts, and other funding mechanisms used across the National Institutes of Health (NIH).

At the request of Congress, the NIH embarked on a process to provide better consistency and transparency in the reporting of its funded research. This new process, implemented in 2008 through the Research, Condition, and Disease Categorization (RCDC) system, uses sophisticated text data mining (categorizing and clustering using words and multiword phrases) in conjunction with NIH-wide definitions used to match projects to categories. RCDC use of data mining improves consistency and eliminates the wide variability in defining the research categories reported. The definitions are a list of terms and concepts selected by NIH scientific experts to define a research category. The research category levels represent the NIH’s best estimates based on the category definitions.

The NIH does not expressly budget by category. The annual estimates reflect amounts that change as a result of science, actual research projects funded, and the NIH budget. The research categories are not mutually exclusive. Individual research projects can be included in multiple categories so amounts depicted within each column of this table do not add up to 100 percent of NIH-funded research.

Consistent with the Administration’s emphasis on transparency, two separate columns are used to distinguish FY 2010 actual support funded from American Recovery & Reinvestment Act (ARRA) accounts from projects funded by regular NIH appropriations.

The table shows historical data for FY 2010 through FY 2013. The FY 2014-2015 estimates are based on RCDC actual data.


Total Number of Research/Disease Areas: 237

Click here for instructions on how to use the data table below.

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Research/Disease Areas
(Dollars in millions and rounded)
FY 2010Actual

(Non-ARRA)
FY 2010Actual

(ARRA) 10/
FY 2011ActualFY 2012ActualFY 2013ActualFY 2014EstimatedFY 2015Estimated
Acute Respiratory Distress Syndrome $110 $22 $96 $98 $95 $97 $97
Adolescent Sexual Activity $80 $7 $69 $76 $70 $72 $72
Agent Orange & Dioxin $11 $1 $8 $8 $10 $10 $10
Aging $2,517 $443 $2,572 $2,593 $2,429 $2,494 $2,494
Alcoholism $454 $65 $452 $455 $437 $448 $448
Allergic Rhinitis (Hay Fever) $3 $1 $7 $7 $9 $9 $9
ALS $47 $12 $44 $44 $39 $40 $40
Alzheimer's Disease $450 $79 $448 $503 $504 $566 $566
American Indians / Alaska Natives $151 $16 $136 $170 $160 $165 $165
Anorexia $9 $2 $11 $14 $11 $12 $12
Anthrax $118 $12 $87 $84 $70 $72 $72
Antimicrobial Resistance $356 $66 $369 $377 $325 $361 $361
Aphasia $21 $1 $21 $24 $24 $24 $24
Arctic $34 $3 $28 $23 $19 $19 $19
Arthritis $249 $59 $231 $258 $231 $237 $237
Assistive Technology $250 $48 $250 $237 $220 $226 $226
Asthma $244 $33 $221 $229 $207 $213 $213
Ataxia Telangiectasia $12 $1 $13 $11 $11 $12 $12
Atherosclerosis $544 $104 $475 $477 $374 $384 $384
Attention Deficit Disorder (ADD) $66 $15 $55 $60 $49 $50 $50
Autism $160 $58 $169 $192 $186 $190 $190
Autoimmune Disease $856 $125 $869 $867 $821 $838 $838
Basic Behavioral and Social Science $1,163 $198 $1,173 $1,215 $1,172 $1,200 $1,200
Batten Disease $5 $1 $4 $4 $5 $5 $5
Behavioral and Social Science $3,526 $603 $3,573 $3,682 $3,535 $3,616 $3,616
Biodefense 1/ $1,794 $221 $1,803 $1,791 $1,692 $1,741 $1,768
Bioengineering $3,166 $760 $3,303 $3,498 $3,234 $3,318 $3,318
Biotechnology $5,682 $1,203 $5,823 $6,089 $5,698 $5,845 $5,845
Brain Cancer $274 $36 $280 $281 $280 $287 $287
Brain Disorders $3,847 $619 $3,864 $3,968 $3,708 $3,796 $3,799
Breast Cancer $763 $61 $715 $800 $657 $674 $674
Burden of Illness $48 $8 $40 $84 $72 $74 $74
Cancer $5,823 $803 $5,448 $5,621 $5,274 $5,418 $5,418
Cardiovascular $2,144 $398 $2,049 $2,040 $1,964 $2,015 $2,015
Cerebral Palsy $19 $3 $23 $42 $18 $19 $19
Cervical Cancer $93 $8 $119 $112 $98 $101 $101
Charcot-Marie-Tooth Disease $15 $1 $13 $13 $11 $11 $11
Child Abuse and Neglect Research $32 $5 $30 $32 $30 $31 $31
Childhood Leukemia $55 $12 $59 $77 $67 $68 $68
Chronic Fatigue Syndrome (ME/CFS) $6 $0 $6 $5 $5 $5 $5
Chronic Liver Disease and Cirrhosis $284 $45 $303 $288 $282 $290 $290
Chronic Obstructive Pulmonary Disease $118 $15 $108 $101 $102 $104 $104
Climate Change $4 $2 $6 $8 $8 $8 $8
Climate-Related Exposures and Conditions 11/ $188 $23 $155 $157 $137 $140 $140
Clinical Research $10,720 $1,540 $10,503 $10,951 $10,604 $10,928 $10,928
Clinical Trials $3,286 $356 $3,093 $3,208 $3,155 $3,237 $3,237
Colo-Rectal Cancer $291 $26 $313 $302 $281 $288 $288
Comparative Effectiveness Research $558 $320 $517 $597 $559 $574 $574
Complementary and Alternative Medicine $521 $55 $442 $493 $380 $389 $389
Conditions Affecting the Embryonic and Fetal Periods 12/ $98 $21 $157 $165 $151 $155 $155
Contraception/Reproduction $419 $56 $415 $448 $408 $418 $418
Cooley's Anemia $20 $3 $20 $20 $15 $16 $16
Cost Effectiveness Research $80 $14 $71 $78 $82 $84 $84
Crohn's Disease $66 $12 $67 $76 $61 $63 $63
Cystic Fibrosis $86 $13 $79 $86 $78 $80 $80
Dementia $0 $0 + $0 $650 $666 $666
Dental/Oral and Craniofacial Disease $497 $67 $501 $516 $480 $492 $492
Depression $420 $50 $426 $429 $415 $422 $422
Diabetes 2/ $1,046 $153 $1,076 $1,061 $1,007 $1,028 $1,039
Diagnostic Radiology $1,073 $280 $1,071 $1,090 $1,079 $1,103 $1,103
Diethylstilbestrol (DES) $4 $1 $3 $3 $1 $1 $1
Digestive Diseases $1,657 $228 $1,698 $1,719 $1,575 $1,617 $1,617
Digestive Diseases - (Gallbladder) $5 $0 $4 $11 $10 $10 $10
Digestive Diseases - (Peptic Ulcer) $30 $3 $18 $20 $19 $19 $19
Down Syndrome $22 $6 $20 $20 $18 $19 $19
Drug Abuse (NIDA Only) 3/ $1,067 $125 $1,051 $1,052 $993 $1,015 $1,023
Duchenne/ Becker Muscular Dystrophy $33 $5 $32 $34 $33 $34 $34
Dystonia $14 $1 $13 $14 $13 $14 $14
Eating Disorders 4/ $28 $4 $27 $34 $31 $31 $31
Emerging Infectious Diseases $2,118 $350 $2,190 $2,153 $1,804 $1,853 $1,853
Emphysema $23 $9 $22 $20 $24 $25 $25
Endometriosis $15 $1 $14 $9 $7 $7 $7
Epilepsy $134 $27 $152 $156 $129 $132 $132
Estrogen $231 $23 $227 $221 $218 $223 $223
Eye Disease And Disorders Of Vision $817 $110 $831 $841 $774 $793 $793
Facioscapulohumeral Muscular Dystrophy $5 $1 $6 $5 $5 $6 $6
Fetal Alcohol Syndrome $33 $5 $36 $32 $33 $34 $34
Fibroid Tumors (Uterine) $12 $2 $12 $14 $10 $10 $10
Fibromyalgia $9 $0 $11 $13 $11 $11 $11
Food Allergies + + $33 $31 $36 $37 $37
Food Safety $290 $35 $287 $257 $229 $235 $235
Fragile X Syndrome $25 $4 $29 $27 $30 $30 $30
Frontotemporal Dementia (FTD) $18 $1 $23 $26 $32 $33 $33
Gene Therapy $248 $32 $248 $256 $226 $232 $232
Gene Therapy Clinical Trials $14 $0 $14 $15 $15 $15 $15
Genetic Testing $298 $121 $270 $255 $272 $277 $277
Genetics $7,473 $1,440 $7,223 $7,632 $7,144 $7,328 $7,330
Global Warming Climate Change $2 $2 $5 $6 $6 $6 $6
Headaches $18 $1 $21 $24 $25 $25 $25
Health Disparities 5/ $2,728 $351 $2,718 $2,740 $2,722 $2,794 $2,794
Health Services $1,143 $334 $1,172 $1,317 $1,262 $1,304 $1,304
Heart Disease $1,329 $235 $1,236 $1,278 $1,230 $1,262 $1,262
Heart Disease - Coronary Heart Disease $457 $80 $437 $468 $404 $415 $415
Hematology $961 $141 $1,006 $1,091 $1,020 $1,050 $1,050
Hepatitis $204 $25 $208 $210 $195 $200 $200
Hepatitis - A $4 $0 $4 $2 $2 $2 $2
Hepatitis - B $66 $4 $58 $51 $48 $49 $49
Hepatitis - C $100 $12 $114 $112 $101 $104 $104
HIV/AIDS 6/ $3,085 $322 $3,059 $3,074 $2,898 $2,978 $3,005
Hodgkin's Disease $24 $1 $20 $21 $13 $14 $14
Homelessness $15 $3 $9 $10 $11 $13 $13
Homicide and Legal Interventions $1 $0 $1 $1 $0 - -
HPV and/or Cervical Cancer Vaccines $25 $2 $24 $26 $25 $25 $25
Human Fetal Tissue 7/ $55 $24 $66 $71 $67 $69 $69
Human Genome $1,904 $598 $1,907 $2,271 $2,473 $2,538 $2,538
Huntington's Disease $65 $7 $56 $65 $55 $57 $57
Hydrocephalus + + + $7 $6 $7 $7
Hyperbaric Oxygen $2 $0 $2 $2 $1 $1 $1
Hypertension $251 $50 $240 $215 $222 $227 $227
Immunization $1,798 $231 $1,756 $1,733 $1,656 $1,699 $1,699
Infant Mortality/ (LBW) $273 $53 $286 $287 $253 $260 $260
Infectious Diseases $3,890 $568 $3,883 $3,867 $4,887 $5,015 $5,015
Infertility $76 $16 $74 $74 $78 $80 $80
Inflammatory Bowel Disease $106 $19 $113 $121 $114 $117 $117
Influenza $308 $88 $272 $251 $304 $312 $312
Injury - Childhood Injuries $36 $3 $33 $37 $37 $38 $38
Injury - Trauma - (Head and Spine) $179 $31 $166 $171 $183 $188 $188
Injury - Traumatic brain injury $85 $9 $81 $79 $88 $91 $91
Injury - Unintentional Childhood Injury $22 $1 $20 $22 $20 $21 $21
Injury (total) Accidents/Adverse Effects $372 $46 $356 $366 $367 $376 $376
Intellectual and Developmental Disabilities (IDD) 12/ $311 $87 $333 $355 $343 $351 $351
Interstitial Cystitis $12 $1 $13 $10 $10 $10 $10
Kidney Disease $552 $98 $557 $556 $551 $565 $565
Lead Poisoning $11 $1 $10 $8 $8 $8 $8
Liver Cancer $102 $10 $74 $73 $71 $73 $73
Liver Disease $627 $85 $623 $632 $594 $610 $610
Lung $1,269 $207 $1,278 $1,286 $1,230 $1,261 $1,261
Lung Cancer $201 $22 $221 $233 $208 $213 $213
Lupus $112 $15 $106 $108 $92 $95 $95
Lyme Disease $24 $5 $28 $25 $20 $21 $21
Lymphoma $195 $14 $199 $213 $233 $239 $239
Macular Degeneration $104 $9 $105 $101 $98 $100 $100
Malaria $134 $14 $145 $152 $147 $151 $151
Malaria Vaccine $41 $4 $39 $40 $34 $35 $35
Mental Health $2,246 $334 $2,275 $2,287 $2,174 $2,215 $2,215
Methamphetamine $73 $14 $70 $69 $68 $70 $70
Migraines $15 + $16 $18 $19 $20 $20
Mind and Body $549 $81 $533 $533 $210 $214 $214
Minority Health 5/ $2,526 $312 $2,504 $2,487 $2,428 $2,493 $2,493
Mucopolysaccharidoses (MPS) $8 $0 $10 $10 $8 $8 $8
Multiple Sclerosis $133 $18 $122 $115 $112 $115 $115
Muscular Dystrophy $74 $12 $75 $75 $76 $78 $78
Myasthenia Gravis $8 $3 $9 $7 $7 $7 $7
Myotonic Dystrophy $10 $2 $9 $10 $10 $11 $11
Nanotechnology 8/ $435 $76 $409 $456 $430 $441 $441
Networking and Information Technology R&D 8/ $647 $248 $551 $532 $521 $536 $536
Neuroblastoma + + $25 $34 $33 $34 $34
Neurodegenerative $1,571 $243 $1,622 $1,671 $1,619 $1,662 $1,662
Neurofibromatosis $24 $1 $23 $18 $17 $18 $18
Neuropathy $121 $10 $146 $145 $151 $155 $155
Neurosciences $5,515 $794 $5,548 $5,618 $5,340 $5,474 $5,477
Nutrition $1,435 $208 $1,411 $1,692 $1,524 $1,561 $1,561
Obesity $824 $147 $830 $836 $812 $834 $834
Organ Transplantation $150 $37 $164 $150 $140 $143 $143
Orphan Drug $512 $89 $749 $809 $764 $787 $787
Osteogenesis Imperfecta $8 $4 $9 $9 $8 $8 $8
Osteoporosis $181 $23 $179 $181 $164 $168 $168
Otitis Media $19 $2 $15 $17 $14 $15 $15
Ovarian Cancer $122 $10 $138 $147 $133 $137 $137
Paget's Disease $1 $0 $1 $1 $0 - -
Pain Conditions - Chronic $360 $44 $386 $396 $402 $413 $413
Pain Research $0 $0 + $479 $475 $488 $488
Pancreatic Cancer + + $112 $127 $125 $128 $128
Parkinson's Disease $154 $18 $151 $154 $135 $139 $139
Patient Safety $859 $263 $839 $845 $858 $881 $881
Pediatric $3,286 $479 $3,277 $3,612 $3,266 $3,339 $3,339
Pediatric AIDS 6/ $216 $15 $228 $219 $188 $192 $192
Pediatric Research Initiative $308 $148 $362 $379 $258 $261 $261
Pelvic Inflammatory Disease $4 $1 $4 $3 $3 $3 $3
Perinatal - Birth - Preterm (LBW) $183 $47 $214 $217 $198 $203 $203
Perinatal - Neonatal Respiratory Distress Syndrome $31 $3 $37 $38 $33 $34 $34
Perinatal Period - Conditions Originating in Perinatal Period $542 $84 $498 $538 $486 $498 $498
Pick's Disease $2 $0 $3 $2 $3 $3 $3
Pneumonia $93 $17 $117 $115 $113 $116 $116
Pneumonia & Influenza $396 $102 $382 $358 $407 $418 $418
Polycystic Kidney Disease $35 $6 $42 $42 $40 $41 $41
Post-Traumatic Stress Disorder (PTSD) $0 $0 + $0 $77 $78 $78
Prescription Drug Abuse $29 $7 $28 $33 $33 $34 $35
Prevention $5,983 $849 $5,929 $5,924 $6,686 $6,853 $6,853
Prostate Cancer $331 $31 $284 $257 $286 $294 $294
Psoriasis $13 $3 $10 $10 $12 $13 $13
Rare Diseases + + $3,527 $3,623 $3,456 $3,553 $3,553
Regenerative Medicine $820 $142 $824 $877 $831 $853 $853
Rehabilitation $458 $93 $459 $449 $446 $458 $458
Rett Syndrome $13 $2 $12 $13 $13 $14 $14
Reye's Syndrome $0 $0 + $0 $0 - -
Rural Health $207 $33 $211 $231 $187 $194 $194
Schizophrenia $276 $63 $264 $268 $232 $236 $236
Scleroderma $19 $2 $25 $24 $21 $21 $21
Screening And Brief Intervention For Substance Abuse $26 $4 $30 $31 $25 $27 $27
Septicemia $90 $17 $91 $96 $88 $91 $91
Sexually Transmitted Diseases/Herpes $250 $38 $259 $275 $242 $248 $248
Sickle Cell Disease $73 $12 $65 $65 $70 $72 $72
Sleep Research $226 $22 $232 $238 $229 $235 $235
Small Pox $92 $5 $41 $40 $30 $31 $31
Smoking and Health $336 $55 $360 $353 $321 $328 $328
Spina Bifida $12 $6 $11 $12 $10 $10 $10
Spinal Cord Injury $87 $16 $78 $79 $94 $96 $96
Spinal Muscular Atrophy $16 $3 $19 $15 $13 $14 $14
Stem Cell Research $1,099 $187 $1,179 $1,374 $1,273 $1,306 $1,306
Stem Cell Research - Embryonic - Human $126 $40 $123 $146 $146 $150 $150
Stem Cell Research - Embryonic - Non-Human $175 $20 $165 $164 $154 $157 $157
Stem Cell Research - Nonembryonic - Human $341 $74 $395 $504 $431 $443 $443
Stem Cell Research - Nonembryonic - Non-Human $570 $74 $620 $653 $613 $629 $629
Stem Cell Research - Umbilical Cord Blood/ Placenta $42 $8 $41 $47 $40 $41 $41
Stem Cell Research - Umbilical Cord Blood/ Placenta - Human $40 $7 $36 $43 $35 $36 $36
Stem Cell Research - Umbilical Cord Blood/ Placenta - Non-Human $5 $1 $10 $8 $7 $8 $8
Stroke $337 $54 $317 $310 $282 $291 $291
Substance Abuse 9/ $1,674 $216 $1,623 $1,634 $1,525 $1,560 $1,568
Substance Abuse Prevention $43 $10 $44 $41 $65 $68 $68
Sudden Infant Death Syndrome $25 $2 $23 $24 $20 $20 $20
Suicide $36 $4 $49 $44 $37 $38 $38
Suicide Prevention $17 $2 $25 $22 $21 $21 $21
Teenage Pregnancy $22 $5 $19 $18 $17 $18 $18
Temporomandibular Muscle/Joint Disorder (TMJD) $16 $1 $18 $21 $19 $19 $19
Tobacco $339 $55 $362 $355 $322 $330 $330
Topical Microbicides $84 $5 $104 $99 $93 $96 $96
Tourette Syndrome $7 $0 $5 $6 $4 $4 $4
Transmissible Spongiform Encephalopathy (TSE) $48 $3 $46 $39 $35 $36 $36
Transplantation $574 $109 $592 $552 $538 $552 $552
Tuberculosis $189 $35 $209 $218 $240 $247 $247
Tuberculosis Vaccine $13 $3 $17 $21 $26 $27 $27
Tuberous Sclerosis $20 $2 $20 $23 $20 $21 $21
Underage Drinking $75 $5 $77 $80 $75 $77 $77
Underage Drinking – Prevention & Treatment (NIAAA Only) 13/ $56 $2 $57 $62 $62 $63 $63
Urologic Diseases $563 $56 $542 $496 $497 $510 $510
Uterine Cancer $26 $4 $40 $42 $39 $40 $40
Vaccine Related $1,737 $222 $1,717 $1,691 $1,608 $1,649 $1,649
Vaccine related (AIDS) 6/ $535 $27 $550 $557 $518 $534 $542
Vector-Borne Diseases $426 $68 $466 $441 $437 $452 $452
Violence Against Women $36 $2 $34 $36 $31 $32 $32
Violence Research $174 $19 $156 $154 $137 $139 $139
Vulvodynia $2 $1 $2 $4 $4 $4 $4
West Nile Virus $46 $6 $65 $29 $40 $41 $41
Women's Health 5/ $3,691 $449 $3,891 $3,833 $3,745 $3,845 $3,845
Youth Violence $102 $10 $87 $77 $70 $71 $71
Youth Violence Prevention $32 $2 $26 $27 $26 $26 $26
[*] The minimum reporting threshold for a specific disease/condition is $500,000. Reporting of $0 does not indicate that no research is being conducted.
[+] Indicates a new category. Funding support data not available prior to the initial year reported.
1/ Reporting for this category does not follow the standard RCDC process. The total amount reported is consistent with reporting requirements for this category to the U.S. Office of Management & Budget (OMB). The project listing does not include non-project or other support costs associated with the annual total for this category. Additional information on this category is available at http://www.niaid.nih.gov/topics/biodefenserelated/pages/default.aspx.
2/ Includes research funded from the Type 1 diabetes appropriation. These are project listings only.
3/ Reporting for this category does not follow the standard RCDC process. Spending for this category is reported consistent with U.S. Office of National Drug Control Policy (ONDCP) requirements. This category includes only projects funded by NIDA. More information on this area is available at http://www.drugabuse.gov/drugs-abuse. The FY 2013 actual and FY 2014 estimate reported in RePORT can differ from levels identified in the FY 2015 Drug Control budget submission for those fiscal years where comparable adjustments have been applied.
4/ Reported total for this category encompasses research for anorexia, bulimia nervosa, binge eating disorders, and eating disorders not otherwise specified.
5/ Reporting for this category does not follow the standard RCDC process. This category assigns project funding according to populations tracked by gender or ethnicity. The databases used to track gender/ethnicity are complex are not currently compatible with the RCDC system.
6/ The total for AIDS research includes both extramural and intramural research (including research management and support, Management Fund, and Service & Supply Fund), buildings and facilities, research training, and program evaluation, as well as research on the many HIV-associated co-infections and co-morbidities, including TB, hepatitis C, and HIV-associated cancers. It also includes all of the basic science underlying this research. Other RCDC categories are not reported this way; thus the total for AIDS-related research is not comparable to spending reported for other RCDC diseases.
7/ Reporting for this category does not follow the standard RCDC process. This category uses a non-standard approach involving subject matter expert reviews of manually collected project listings.
8/ The data provided reflects funding amounts reported by the NIH RCDC process for this category. Actual and estimate levels presented on this site supersede estimates detailed in OMB MAX DE application tables that may have been based on preliminary funding support information.
9/ Reporting for this category does not follow the standard RCDC process. This category includes all spending reported under the Drug Abuse category as well as projects categorized under the broader area of Substance Abuse. These are project listings only. More information on this area is available at http://www.drugabuse.gov/drugs-abuse.
10/ Separate columns are used to distinguish FY 2010 actual support funded from American Recovery & Reinvestment Act (ARRA) accounts from projects funded by regular annual NIH appropriations.
11/ Prior to FY 2011, this category's title was "Health Effects of Climate Change". The title was revised to more accurately reflect the content of the research conducted and facilitate reporting spending data in response to requests tracking climate change adaptation.
12/ Name revised in FY 2013 to reflect current scientific terminology.
13/ Reporting for this category does not follow the standard RCDC process. Spending is reported consistent with U.S. Office of National Drug Control Policy (ONDCP) requirements. This category includes only projects funded or administered by NIAAA. This category includes a subset of spending reported under the Underage Drinking category involving subject matter expert reviews of manually collected project listings. More information on this area is available at http://www.niaaa.nih.gov/research/major-initiatives/underage-drinking-research-initiative.

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