Integrated Risk Information System (IRIS)
EPA's Integrated Risk Information System (IRIS) is a human health assessment program that evaluates information on health effects that may result from exposure to environmental contaminants. Through the IRIS Program, EPA provides the highest quality science-based human health assessments to support the Agency's regulatory activities. The IRIS database is web accessible and contains information on more than 550 chemical substances. Learn more.
What's New in IRIS
- 12/15/14: EPA announces the schedule for the IRIS Bimonthly Public Science Meetings for 2015 in the Federal Register.
- 12/11/14: EPA announces the availability of the presentations from the NRC Recommendations for IRIS Workshop and the presentations from the October 2014 bimonthly science meeting.
- 12/08/14: EPA is announcing that dibutyl phthalate (DBP) has been added to the agenda for the February bimonthly meeting. The deadlines for DBP discussant registration and comments are posted on the February 25-26, 2015 IRIS Bimonthly Public Meeting.
- 12/08/14: EPA announces the availability of the Libby Amphibole Asbestos IRIS Assessment in a December 8, 2014 Press Release. In addition, a fact sheet and frequently asked questions are also available.
- 11/21/14: EPA has canceled the December Bimonthly Public Science Meeting on BBP and DIBP and will discuss these chemicals at the February 25-26, 2015 IRIS Bimonthly Public Meeting. EPA opens registration for the February Meeting.
- 11/17/14: SAB announced in the Federal Register a public teleconference of the Science Advisory Board Chemical Assessment Advisory Committee Augmented for the Review of EPA’s Draft Ammonia Assessment.
- 10/15/14: EPA announced that the IRIS Bimonthly Public Science Meetings will be supplemented by scientific experts identified by the National Research Council (NRC).
- 9/25/14: EPA announces the availability of the draft IRIS assessment of benzo[a]pyrene for peer review by the SAB-CAAC Panel.
Preliminary Draft Materials (by Chemical)
Draft Assessments under Review
- Ammonia - Revised Aug 2013
- Benzo[a]pyrene - Released Sep 2014
- Ethylene Oxide (inhalation cancer) - Revised Aug 2014
- Trimethylbenzenes - Revised Aug 2013
Top 3 Tasks
IRIS Calendar
IRIS Science Blogs
IRIS Quick Links
Have General Comments for the IRIS Program?
In response to public feedback, EPA has opened a "General Comments Docket" to receive feedback that has broad applicability to the IRIS Program. Comment in the General Docket
NOTE: This docket does not replace the IRIS Hotline, but rather provides another avenue to submit feedback to the IRIS Program.