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Research and Clinical Trials

Department of Surgery at University of North Texas Health Science Center has always laid emphasis on research and the betterment of patient care from the benefits of clinical research trials.

Previous clinical trials at the Department of Surgery

1. Post-Op Hernia Pain Study
   Principal Investigator – Dr. Adam Smith (General Surgeon)
   Enrolled – 33 patients
   Studied the effectiveness of post-op pain medication in comparison to a placebo. This clinical study was conducted in various sites across the United States and University of North Texas Health Science Center had the highest number of enrollees.
   

2. Peripheral Vascular Disease Study
   Principal Investigator – Dr. Don Peska (Vascular Surgeon)
   Investigated a new drug to prevent further episodes of peripheral vascular disease.
   

3. Bladder Cancer Study
   Principal Investigator – Dr. Adam Smith
   
4. Laparoscopic Cholecystectomy Study
   Principal Investigator – Dr. Adam Smith
   This is a device study. It compares the effectiveness of Electrocautery vs a Harmonic Scalpel during a laparoscopic removal of the gall bladder.
   
5. Lower Abdominal Surgery Post-Op Pain Study
   Principal Investigator – Dr. Adam Smith
   This study compares the different doses of a pain medication versus a base dose of that medication.
   
6. General Surgery (including knee surgery) Post-Op Pain Study
   Principal Investigator – Dr. Al Yurvati
   This is also a study comparing the effectiveness of post-op pain medications.
   
7. Coronary Artery Bypass Graft Post-Op Pain Study
   Principal Investigator – Dr. Al Yurvati
   This study compares the effectiveness of a new investigational pain medication versus a placebo in Post-Coronary Artery Bypass Graft patients.
   
8. CHARISMA Trial
   Principal Investigator – Dr. Don Peska
   This study is about the prevention of further occurrence of ischemic complications in patients with known coronary artery disease, peripheral vascular disease, hypertension, and stroke.
   
9. Ear Wax Study
   Principal Investigator – Dr. Randall Phillips
   This study investigates a new solution to treat impacted cerumen problems.
   
10. Intra-abdominal Abscess Infection Study
    Principal Investigator – Dr. German Berbel
    This is the study of a new investigational drug to treat infections.

Current Trials

1. Fibrin Sealant
   Principal Investigator: Dr. Albert Yurvati
   
2. Prospective, Non-interventional Registry for Ovarian, Lung, and Colon Cancer Patients Utilizing the Extreme Drug Resistance Assay (ARQIVE)
   Principal Investigator: Dr. Albert Yurvati
   
3. Stem Cell Research
   Principal Investigator: Dr. Albert Yurvati
   

Additional Information

Please feel free to contact

Bonnie Wicklund, RN, BSN, CRCIII 

Clinical Research Coordinator III

Phone: 817-735-0304

e-mail: bonnie.wicklund@unthsc.edu