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Pioneer Award |
New Innovator Award |
Transformative Research Award |
Early Independence Award |
Target group |
- Individuals of exceptional creativity proposing highly innovative research
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- Individual early stage investigators of exceptional creativity proposing research of uncommonly high potential impact
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- Individuals or teams proposing transformative research with perhaps very large budgets
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- Outstanding junior scientists wishing to “skip the post-doc” and immediately begin independent research
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Eligibility |
- Open to all career stages; early and middle career particularly encouraged to apply
- Must currently be engaged in research
- No citizenship or residency requirement
- Foreign (non-U.S.) institutions not eligible
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- Receipt of most recent doctoral degree (e.g., Ph.D., M.D., D.D.S., D.V.M., Pharm.D., or equivalent) or completion of medical internship and residency no more than 10 years prior to application receipt date
- Must be a “new investigator” (never been awarded an R01 or equivalent NIH grant)
- No citizenship or residency requirement
- Foreign (non-U.S.) institutions not eligible
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- Open to all career stages
- Foreign (non-U.S.) institutions eligible
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- Candidate must receive terminal research degree or complete medical residency within 12 months (before or after) of application submission date
- No citizenship or residency requirement
- Foreign (non-U.S.) institutions not eligible
- Only up to two applications per institution (or grant submitting entity)
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Preliminary Data |
Not required; may be included |
Not required; may be included |
Not required; may be included |
Not as stringent as conventional R01 |
Research strategy |
3–5 page essay includes response to questions about the challenge, potential impact, suitability for the Pioneer Award program; and how research qualifies as new research direction |
10-page essay addresses significance and potential impact; innovativeness of approaches and how risks and challenges will be addressed; and investigator qualifications for the award |
12-page limit; respond to questions about the challenge, potential impact, and appropriateness for the T-R01 program |
12-page limit; in addition, host institution must provide details of commitment |
Reference letters |
3 letters required |
None accepted |
None accepted |
3 -5 letters required |
Effort |
Minimum of 51% (major portion) of research effort must be devoted to activities supported by the award |
Minimum of 25% of research effort must be devoted to activities supported by the award |
Effort should be commensurate with project needs, and follow general guidelines for other NIH projects of similar size, complexity, and duration |
Large fraction of total effort |
Budget |
- No budget information submitted
- Awards will be for up to $500,000 per year for each of five years, plus standard F&A (indirect) costs
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- No budget information submitted
- Awards will be for up to $300,000 in direct costs each year for five years, plus standard F&A (indirect costs)
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- No limits up to maximum funds available for the program as a whole
- No prior approvals required for budgets over $500K (DC) per year
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Up to $250K per year for up to five years, plus standard F&A (indirect costs) |
Multiple PIs |
Only one PD/PI may be designated on the application |
Only one PD/PI may be designated on the application |
More than one PD/PI allowed |
Only one PD/PI may be designated on the application |
Review format |
Multi-phased, interview of finalists |
Multi-phased, “editorial board” |
Multi-phased, “editorial board |
Multi-phased, “editorial board,” interview of finalists |