Human Papillomavirus
papillomavirus

Genital HPV infection is a sexually transmitted disease (STD) that is caused by human papillomavirus (HPV). Human papillomavirus is the name of a group of viruses that includes more than 100 different strains or types. More than 30 of these viruses are sexually transmitted, and they can infect the genital area of men and women including the skin of the penis, vulva (area outside the vagina), or anus, and the linings of the vagina, cervix, or rectum.

All types of HPV can cause mild Pap test abnormalities which do not have serious consequences. Approximately 10 of the 30 identified genital HPV types can lead, in rare cases, to development of cervical cancer. Research has shown that for most women (90 percent), cervical HPV infection becomes undetectable within two years. Although only a small proportion of women have persistent infection, persistent infection with "high-risk" types of HPV is the main risk factor for cervical cancer.

Medical Surveillance Monthly Reports
Medical Surveillance Monthly Reports
Learn about HPV and the HPV Vaccine; an interactive webcast, presented by Jay Montgomery, MD, of the VHC - Portsmouth.
COGARD PDF 06 Sep 12
HUMAN PAPILLOMAVIRUS (HPV) VACCINE FOR MALES
ALCOAST PDF 28 Mar 07
GARDASIL - HUMAN PAPILLOMAVIRUS (HPV) VACCINE
23 Nov 09

Sample Q&A: The Disease

How do you know if you have Human Papillomavirus?

The virus lives in the skin or mucous membranes and usually causes no symptoms. Since a majority of HPV infections have no signs or symptoms, most people that are infected are completely unaware and can continue to transmit the virus to sex partner(s).

Depending on the type of HPV, some women have infections that cause abnormal cell growth (dysplasia) on the female cervix. A woman may only find out she has HPV when her annual Pap smear results indicate abnormal cervical cell changes.

Other types of HPV cause visible genital warts. In women, these growths may develop inside the vagina, where they are hard to detect. They can also develop on the lips of the vagina or around the anus. In men, they usually appear on the penis, but they are also found on the scrotum or around the anus.

The growths are typically soft, moist, pink or red swellings and are usually painless but may itch. If allowed to grow, they can block the openings of the vagina, urethra, or anus and become very uncomfortable. They can be single or multiple growths or bumps, raised or flat, small or large and sometimes form a cauliflower-like shape. Depending on their location, genital warts can cause sores and bleeding.

CDC/Office of the Chief Science Officer/ Immunization Safety Officer
Quadrivalent Human Papillomavirus Vaccine Initiation, Coverage, and Compliance Among U.S. Active Component Service Women, 2006-2011 -  Consistent with ACIP recommendations, the DoD has made the HPV4 vaccine available to all eligible service members aged 17–26 years. Despite vaccine availability, utilization of the HPV4 vaccine by active component U.S. service women has been reported to be low.
AAP recommends immunization against human papillomavirus (HPV) for all 11- through 12-year-old children as part of the adolescent immunization program.
Package Insert - Vaccine
Package Insert - Vaccine
Cervarix 19 Oct 09
Bivalent Human Papillomavirus (Types 16 and 18) Recombinant Vaccine
Challenge to Eliminate Cervical Cancer
Gardasil 09 Jun 06
Quadrivalent Human Papillomavirus (Types 6, 11, 16, 18) Recombinant Vaccine
Centers for Disease Control and Prevention
VIS
Vaccine Information Statement (Interim)
Vaccine Information Statement (Interim)
Time 08 Jan 13
HPV cases remain high despite vaccine
Author(s): Slade BA, Leidel L, Vellozzi C, Woo EJ, Hua W, Sutherland A, Izurieta HS, Ball R, Miller N, Braun MM, Markowitz LE, Iskander J
Publication: JAMA, Vol 302, No. 7
Subject: Vaccine-Safety
Disease: 
Human Papillomavirus