- Title
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Microbe-dependent
CD11b + IgA+ plasma cells mediate robust early-phase intestinal IgA responses in mice Open - Authors
- Pictorial Summary
- Summary
- Intestinal plasma cells contribute to the delicate balance between immunity against pathogens and tolerance of intestinal microflora. Kunisawa et al. identify a subpopulation of plasma cells whose proliferation depends on stimulation by microbes and IL-10, and which mediate early-phase responses to oral antigens.
- Date
- 23 Apr
- Reference
- Nat. Commun. 4 : 1772
- doi:
- 10.1038/ncomms2718 (2013)
- Terms
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Most recent
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Nanobatteries in redox-based resistive switches require extension of memristor theory Open
- Authors
- Pictorial Summary
- Summary
- The original definition of a memristor envisions a two-terminal memory device with a pinched, zero-crossing hysteresis loop. As the authors show here, an electromotive force leads to non-zero-crossing characteristics in nanoionic-type memristors, implying that the memristor definition must be amended.
- Date
- 23 Apr
- Reference
- Nat. Commun. 4 : 1771
- doi:
- 10.1038/ncomms2784 (2013)
- Terms
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- Title
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Visualization and genetic modification of resident brain microglia using lentiviral vectors regulated by microRNA-9
- Authors
- Pictorial Summary
- Summary
- Microglia are specialized immune cells in the brain. Here Åkerblom and colleagues use a microRNA-9-regulated lentiviral vector for the targeted genetic modification of microglia in the rodent brain, presenting a tool that may facilitate functional studies of resident microglia.
- Date
- 23 Apr
- Reference
- Nat. Commun. 4 : 1770
- doi:
- 10.1038/ncomms2801 (2013)
- Terms
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- Title
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miR-155 regulates differentiation of brown and beige adipocytes via a bistable circuit Open - Authors
- Pictorial Summary
- Summary
- Brown fat can dissipate energy as heat and has an important role in energy homoeostasis of rodents and possibly humans. Chen et al. show that microRNA 155 regulates the differentiation of brown adipocytes as well as the 'browning' of white fat cells in mice.
- Date
- 23 Apr
- Reference
- Nat. Commun. 4 : 1769
- doi:
- 10.1038/ncomms2742 (2013)
- Terms
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- Title
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Trapping red blood cells in living animals using optical tweezers
- Authors
- Pictorial Summary
- Summary
- Optical tweezers based on focused laser beams are widely used for biophysical measurements of single molecules in vitro. Here Zhong et al. use infrared optical tweezers to trap and manipulate red blood cells within subdermal capillaries in living mice.
- Date
- 23 Apr
- Reference
- Nat. Commun. 4 : 1768
- doi:
- 10.1038/ncomms2786 (2013)
- Terms
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- Title
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Genomic deletions disrupt nitrogen metabolism pathways of a cyanobacterial diatom symbiont Open
- Authors
- Pictorial Summary
- Summary
- Cyanobacterial symbionts of marine diatoms can localize intracellularly or externally to their host partners. Here Hilton et al. describe the genomes of two diazotroph cyanobacterial symbionts of diatoms and show that the location of the symbiont affects expression of nitrogen assimilation genes.
- Date
- 23 Apr
- Reference
- Nat. Commun. 4 : 1767
- doi:
- 10.1038/ncomms2748 (2013)
- Terms
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- Title
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The four-transmembrane protein IP39 of Euglena forms strands by a trimeric unit repeat Open
- Authors
- Pictorial Summary
- Summary
- IP39 is an abundant protozoan protein known to form highly-ordered striations in Euglena gracilis’ plasma membrane. Here, Suzuki et al. determine its three-dimensional structure by electron crystallography revealing that IP39 polymerises to form trimeric longitudinal units arranged in a molecular strand of antiparallel double-rows.
- Date
- 23 Apr
- Reference
- Nat. Commun. 4 : 1766
- doi:
- 10.1038/ncomms2731 (2013)
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- Title
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Referential gestures in fish collaborative hunting
- Authors
- Pictorial Summary
- Summary
- Referential gestures such as pointing direct attention towards an object and have only been observed in apes and ravens. Vail et al. show that fish signal to indicate the location of hidden prey to hunting partners, demonstrating that referential gestures are not restricted to large-brained species.
- Date
- 23 Apr
- Reference
- Nat. Commun. 4 : 1765
- doi:
- 10.1038/ncomms2781 (2013)
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- Title
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Neolithic mitochondrial haplogroup H genomes and the genetic origins of Europeans
- Authors
- Pictorial Summary
- Summary
- Here, Brotherton and colleagues sequence 39 mitochondrial genomes from ancient human remains. They track population changes across Central Europe and find that the foundations of the European mitochondrial DNA pool were formed during the Neolithic rather than the post-glacial period.
- Date
- 23 Apr
- Reference
- Nat. Commun. 4 : 1764
- doi:
- 10.1038/ncomms2656 (2013)
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- Title
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Relativistic electron mirrors from nanoscale foils for coherent frequency upshift to the extreme ultraviolet Open
- Authors
- Pictorial Summary
- Summary
- By reflecting light from a relativistically moving mirror, its frequency can be changed, which could create X-rays from visible light. Kiefer et al. make such a mirror from relativistic electrons formed by an intense laser striking a nanofoil, and shift a laser pulse from the infrared to the extreme ultraviolet.
- Date
- 23 Apr
- Reference
- Nat. Commun. 4 : 1763
- doi:
- 10.1038/ncomms2775 (2013)
- Terms
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