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Volume 18, Number 5—May 2012

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Research

Medscape CME Activity
N. Nagata et al.
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Amebic colitis is increasing among younger men who have syphilis or HIV.

Medscape CME Activity
S. N. Ladhani et al.
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Incidence of serotype e was 3-fold lower than serotype f, but it caused more severe clinical disease.

G. J. Tyrrell et al.
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A single clone of Streptococcus pneumoniae serotype 5 caused this epidemic.

D. A. Tadesse et al.
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Determining drug resistance trends will optimize treatment and public health responses.

C. D. Cruz et al.
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Interventions are needed to reduce human exposure to hantaviruses.

H. Yu et al.
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Screening delayed spread by <4 days; autumn school holidays reduced the effective reproduction number by ≈40%.

R. Petersen et al.
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Reduced genetic diversity possibly resulted from introduction of pertussis vaccines

R. Eckhardt et al.
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Imported malaria cases in adults are strongly patterned by neighborhood economic and immigration levels.

R. G. Maggi et al.
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Prevalence of Bartonella spp. was high, especially among patients with a history of Lyme disease.

M. J. Frost et al.
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An encephalitis outbreak among horses was caused by a pathogenic variant of Kunjin virus.

S. M. Mahmud et al.
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Receipt of seasonal inactivated trivalent vaccine neither increased nor decreased the risk for pandemic influenza virus infection.

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Dispatches

H. Lin et al.
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Knowing whether a patient has multidrug-resistant tuberculosis is crucial for prescribing the best treatment. The challenge is choosing the most effective drug with the fewest side effects while saving the “big guns” for the most resistant infections. The best way to find out whether a patient has this type of infection is to conduct drug-susceptibility testing. Unfortunately, this testing requires laboratory capabilities that are in short supply, so often only patients at high risk are tested. But who is at high risk? A recent study found an association between patients’ locations (health center at which they were seen) and likelihood of multidrug-resistant infection. Added to other known risk factors (young age, previous TB treatment, or contact with someone with similar infection), this information can further pinpoint who should be tested, which will ultimately lead to faster diagnoses, better treatments and less spread of multidrug-resistant TB.

G. G. Arzey et al.
A. J. Ramis et al.
Z. Xiang et al.
M. E. Reller et al.
S. Calvignac-Spencer et al.
S. Lindstrom et al.
S. M. Cacciò et al.
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The world is home to more than 1 billion pigs, which produce large quantities of feces. We know that some organisms in pig feces can cause human disease, and now we might have another to add to the list. Little is known about where the common intestinal parasite Dientamoeba fragilis comes from and how it is spread. However, recent molecular analysis confirmed that the organism found in pigs is indeed the same as the one found in humans. Therefore, pigs (or their feces) might be a source of this parasitic infection in humans.

V. B. Kute et al.
Y. Matsushima et al.
T. Oishi et al.
M. Yusof et al.
M. Pérez-Ruiz et al.
C. Adlhoch et al.
W. H. Self et al.
M. J. Hale et al.
S. D. Pas et al.
L. E. Lee et al.
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Sapovirus gives new meaning to the phrase “cradle to grave.” Historically, sapovirus has been associated with gastrointestinal illness in children living in group settings such as hospitals, shelters, or refugee camps. But now, sapovirus outbreaks are occurring among elderly residents of long-term care and similar facilities. These elderly residents are especially vulnerable to rapidly transmitted gastrointestinal viruses and serious complications. This virus has been making the rounds in long-term care facilities since 2002, and outbreaks started increasing in 2007. Sapovirus testing should be added to routine diagnostic workups for gastrointestinal infections, regardless of patient age group. Results can be used to develop prevention, control, and treatment guidelines, especially for vulnerable elderly populations.

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Conference Summaries

Material Available Online Only
T. F. Wierzba and U. Panzner

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Risk Factors for Intestinal Invasive Amebiasis in Japan, 2003–2009

p. 719

Temporal Trends in <em>Bordetella pertussis</em> Populations, Denmark, 1949–2010

p. 770

Pigs as Natural Hosts of <em>Dientamoeba fragilis</em> Genotypes Found in Humans

p. 839

<em>Plasmodium vivax</em> Malaria–associated Acute Kidney Injury, India, 2010–2011

p. 842

Fatal Human Co-infection with <em>Leptospira</em> spp. and Dengue Virus, Puerto Rico, 2010

p. 879

Novel Prion Protein in BSE-affected Cattle, Switzerland

p. 891
 

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