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"diagnostic testing"

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This slide discusses study population and applicability.  It presents a table divided into two columns with one header row and six data rows. Column one is titled “Conditions that limit applicability” and column two is titled “Features that should be extracted into evidence tables.” Each of the six data rows contains conditions described in column one and associated features to be extracted in column two.  In the first row, the limiting conditions are: narrow eligibility criteria, high exclusion rate, low enrollment. The features that should be extracted are: eligibility criteria and proportion of screened individuals enrolled. In the second row, limiting conditions are: differences between patients in study and the community. The features that should be extracted are: demographics (range and mean): age, gender, race and ethnicity.  In the third row, the limiting conditions are: narrow or unrepresentative severity or stage of illness. The features that should be extracted are: severity or stage of illness (referral or primary care population). In the fourth row, limiting conditions are: run-in periods with high exclusion rates. The features that should be extracted are: run-in period: attrition rate before randomization and reason (e.g., nonadherence, adverse drug events and no response). In the fifth row, limiting conditions are: event rates markedly different than in community. The features that should be extracted are: event rates in treatment and control groups. In the sixth row, limiting conditions are: disease prevalence in study population different than community. The features that should be extracted are: prevalence of disease (for diagnostic studies).

Population and Applicability

Data Elements: Population, Intervention, and Comparator. Population-generic elements may include patient characteristics, such as age, gender distribution, and disease stage. More specific items may be needed, depending upon the topic. Intervention or exposure and comparator items depend upon the abstracted study. Study types include randomized trial, observational study, diagnostic test study, prognostic factor study, family-based or population-based genetic study, et cetera.

Data Elements: Population, Intervention, and Comparator

Diagnosis and Treatment of Obstructive Sleep Apnea in Adults

Background: Using Noninvasive Technologies To Diagnose Coronary Artery Disease (1 of 2)

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