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Substitutes in Non-Mechanical Heat Transfer Systems
Substitutes are reviewed on the basis of ozone depletion potential, global warming potential, toxicity, flammability, and exposure potential. Lists of acceptable and unacceptable substitutes are updated several times each year. A chronological list of SNAP updates is also available.
Unacceptable substitutesNote: SNAP-related information published in the Federal Register takes precedence over all information on this page.
Acceptable Substitutes for CFCs (class I ODS) in Non-Mechanical Heat Transfer Systems
| Substitute (Name Used in the Federal Register) | Trade Name | Refrigerant Being Replaced | Retrofit/ New |
|---|---|---|---|
| R-744 (Carbon Dioxide, CO2) | all CFCs | R, N | |
| Water | all CFCs | R, N | |
| Mineral Oil | all CFCs | R, N | |
| Volatile Methyl Siloxanes | all CFCs | R, N | |
| Galden Fluids | all CFCs | R | |
| HFC-236fa | 114 | R, N | |
| HFE-7100 | 11, 12, 113, 114, 115 | R, N | |
| HFC-4310mee | all CFCs | R, N | |
| HFE-7200 | 11, 12, 113, 114, 115 | R, N | |
| Hydrofluoroether 7000 | HFE-7000 | 11, 113 | R, N |
| R-407C | Suva 407C, Klea 407C | 502 | R, N |
| R-422C | ICOR XLT1 | 502 | R, N |
| HCF-245fa | Genetron® 245fa | 11, 113 | R, N |
| KDD6 | KDD6 | 12 | R, N |
| C6 perfluoroketone | NovecTM 649 | 113 | R, N |
| HFO-1234ze (E) | HFO-1234ze (E) | 113 | R, N |
| C7 Fluoroketone | Novec™ 774 | 113 | R, N |
Key: R = Retrofit Uses, N = New
Uses
Acceptable Substitutes for HCFCs (class II ODS) in Non-Mechanical Heat Transfer Systems
| Substitute (Name Used in the Federal Register) | Trade Name | Refrigerant Being Replaced | Retrofit/ New |
|---|---|---|---|
| HFE-7100 | 22, blends containing 22 and/or 142b | R, N | |
| HFC-4310mee | all HCFCs | R, N | |
| ISCEON 59, NU-22, R-417A | ISCEON 59, NU-22 | 22, blends containing 22 and/or 142b | R, N |
| HFE-7200 | 22, blends containing 22 and/or 142b | R, N | |
| R-422D | ISCEON MO29 | 22, blends containing 22 and/or 142b | R, N |
| KDD5, R-438A | ISCEON MO99 | 22, blends containing 22 and/or 142b | R, N |
| HCF-245fa | Genetron® 245fa | 21, 141b, 22, blends containing 22 and/or 142b | R, N |
| R-125/290/134a/600a (55.0/1.0/42.5/1.5) | ICOR AT-22 | 22, blends containing 22 and/or 142b | R, N |
| R-422B | XAC1, NU-22B | 22, blends containing 22 and/or 142b | R, N |
| R-422C | XLT1 | 22, blends containing 22 and/or 142b | R, N |
| C6 perfluoroketone | NovecTM 649 | 22, blends containing 22 and/or 142b | R, N |
| HFO-1234ze (E) | HFO-1234ze (E) | 22, blends containing 22 and/or 142b | R, N |
| Volatile Methyl Siloxanes | 22, blends containing 22 and/or 142b | R, N | |
| R-744 (Carbon Dioxide, CO2) | 22, blends containing 22 and/or 142b | R, N | |
| Water | 22, blends containing 22 and/or 142b | R, N | |
| R-404A | 22 and blends containing HCFCs | R, N | |
| R-407C | 22 and blends containing HCFCs | R, N | |
| R-410A | 22 and blends containing HCFCs | N | |
| HFE-7000 | 22, blends containing 22 and/or 142b | R, N |
Key: R = Retrofit Uses, N = New
Uses
Substitutes for CFCs in Non-Mechanical Heat Transfer Systems Acceptable Subject to Narrowed Use Limits
| Substitute | ODS Being Replaced | Narrowed Use Limit | Retrofit/ New |
|---|---|---|---|
| PFCs (C3F8, C4F10, C5F12, C5F11NO, C6F14, C6F13NO, C7F16, C7F15NO, C8F18, C8F17NO, C9F21N) | all CFCs | PFCs are only allowed in new systems where a study has demonstrated that no other alternatives are technically feasible due to safety or performance requirements; this study must be kept available for review. | R, N |
Key: R = Retrofit Uses, N = New
Uses