PROGRAM
Only public information will be presented.

Wednesday, July 7

7:30 am Registration starts, UT Conference Center, 4th floor

8:00 - 9:00 breakfast

Morning Session
Chair: Dean Myles
9:00 - 9:10 Welcome address - Dean Myles
9:10 - 10:30 Key Note Talk - Lucy Malinina - "Protein-based Structural Biomedicine" (Part 1)(Part 2)(Part 3)
10:30 - 10:45 Coffee break
10:45 - 11:45 - Dean Myles - "Neutrons, Protons and Proteins:  Hydrogen Atoms in Biological Function"
11:45 - 12:45 - Emad Tajkhorshid - "Visualizing the Art of Active Transport Across Cellular Membranes at Sub-Angstrom Resolution"
12:45 - 1:45 Lunch

Afternoon session
Chair: Cynthia Peterson
1:45 - 3:05 Keynote talk - Andrew McCulloch - "Multi-Scale Modeling and Systems Biology of the Heart"
3:05 - 3:25 Coffee break
3:25 - 4:25 - Edward Trifonov - "30 Years of Nucleosome Positioning Agony, and Finale"
4:25 - 5:25 -Jaewook Joo - "Predictive Modeling of Information Processing on Cell Signaling Networks"
6:00 - 9:00 Poster session dinner - To be held at The Foundry.

Thursday, July 8

8:00 - 9:00 breakfast

Morning Session
Chair: Jerome Baudry
9:00 - 10:20 Key Note Talk - Zaida (Zan) Luthey-Schulten - "Simulations and Visualization of Dynamics in RNA:Protein Complexes"
10:20 - 10:40 Coffee break
10:40 - 11:40 - Sergey Gavrilets - "Dynamics of Large-scale Evolutionary Diversification: Contrasting Theory and Data"
11:40 - 12:40 - Rommie Amaro - "Tackling Receptor Flexibility in Computer-Aided Drug Design"
12:40 - 1:40 Lunch

Afternoon Session - Meet the Prominent
Chair: Engin Serpersu
1:40 - 5:00 The session is composed of parallel round table discussions with prominent scientists including keynote speakers. Students rotate every 20 minutes. Refreshments will be provided.

Friday, July 9

8:00 - 9:00 breakfast

Morning Session
Chair: Andrey Gorin
9:00 - 10:20 Key Note talk - Maxim Frank-Kamenetskii -"Targeting Duplex DNA: Strategies and Applications"
10:20 - 10:40 Coffee break
10:40 - 11:40 - Barry Bruce - "What Makes TOC-TICK? Insights into Mechanism of Protein Translocation into Chloroplasts"
11:40 - 12:40 - Ashley Spies - "Exploiting Enzyme Plasticity in Drug Discovery"
12:40 - 1:40 Lunch

Afternoon session
Chair: Xiaolin Cheng
1:40 - 3:00 Key Note Talk - Robert Eisenberg - "Ions in Water and Proteins: the Liquid of Life"
3:00 - 3:20 Coffee break
3:20 - 4:20 - Phil Andrews - "Supercomputing at the University of Tennessee, and Some Earlier Medical Applications"
4:20 - 5:20 -Nikolay Dokholyan - "Multiscale Modeling and Design of Biological Molecules"

Saturday, July 10

8:00 - 9:00 breakfast

Morning Session
Chair: Alexei Sokolov
9:00 - 10:20 Key Note Talk - Ruben Abagyan -"Challenges in Chemogenomics and Structure Based Drug Discovery."
10:20 - 10:40 Coffee break
10:40 - 11:40 - Cynthia Peterson, BCMB, UT - "Metals Modulate Interactions and Activities Among Regulators of Extracellular Proteolysis"
11:40 - 11:45 Closing remarks

Oak Ridge National Laboratory