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Clostridium difficile Infections: Diagnosis, Treatment, and Prevention

This figure shows a sample working framework. It begins on the left side with persons at risk. A solid arrow labeled “Screening” leads to a round-edged rectangle that represents “Early Detection of a Target Condition.” A curvy arrow leads down to an oval representing “Adverse Effects of Screening.” A solid arrow labeled “Treatment” leads right from the first box to another round-edged rectangle representing “Intermediate Outcomes.” Another curvy arrow leads down to an oval representing “Adverse Effects of Treatment.” Finally, a dotted line leads from the “Intermediate Outcomes” box to a sharp-edged box that represents the ultimate health outcome: “Reduced Morbidity and/or Mortality.”

Sample Working Framework

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