Appendix C: Site Specific Coding Modules
2012 SEER Coding and Staging Manual
Appendix C brings together the site-specific instructions needed to abstract a case, facilitating efficiency and accuracy. The site-specific coding modules include SEER Coding Guidelines; Equivalent Terms, Definitions, Tables, Charts and Illustrations; Multiple Primary Rules; Histology Coding Rules; Collaborative Stage Coding Instructions1 and Surgery of Primary Site codes2.
General instructions in the main manual are applicable in the absence of site-specific instructions. All modules include the collaborative stage and surgery codes, and multiple primary and histology coding rules. Some modules include site-specific coding guidelines. The goal is to have stand-alone modules for major anatomic sites.
Summary of Changes for Appendix C (PDF) provides the list of changes included in this release.
Collaborative Stage (CS) Data Collection System
Note: The links on this page go to the CS staging schemas in version 02.04 of the the Collaborative Stage Data Collection System.
Required SEER Site-Specific Factors for Collaborative Stage
Oral Cavity
- MP/H Coding Rules: Head and Neck - (C00.0-C14.8, C30.0-C32.9)
- CS Staging Schemas
- Lip, Upper (C00.0, C00.3)
- Lip, Lower (C00.1, C00.4, C00.6)
- Other Lip (C00.2, C00.5, C00.8-C00.9)
- Base of Tongue, Lingual Tonsil (C01.9, C02.4)
- Anterior 2/3 of Tongue, Tip, Border, and Tongue, NOS (C02.0-C02.3, C02.8-C02.9)
- Gum, Upper (C03.0)
- Gum, Lower and Retromolar Area Retromolar Gingiva (Trigone) (C03.1, C06.2)
- Gum, NOS (C03.9)
- Floor of Mouth (C04.0-C04.1, C04.8-C04.9)
- Hard Palate (C05.0)
- Soft Palate, Uvula (C05.1-C05.2)
- Other Mouth (C05.8-C05.9, C06.8-C06.9)
- Cheek (Buccal) Mucosa, Vestibule (C06.0-C06.1)
- Surgery Codes
- Oral Cavity - (C00.0-C00.9, C01.9, C02.0-C02.9, C03.0-C03.9, C04.0-C04.9, C05.0-C05.9, C06.0-C06.9)
Parotid, Other and Unspecified Glands
- MP/H Coding Rules: see Head and Neck (Oral Cavity)
- CS Staging Schemas
- Surgery Codes
- Parotid and Other Unspecified Glands - (C07.9, C08.0-C08.9)
Pharynx, Tonsil, Oropharynx, Hypopharynx, Pyriform Sinus
- MP/H Coding Rules: see Head and Neck (Oral Cavity)
- CS Staging Schemas
- Tonsil, Oropharynx (C09.0-C09.1, C09.8-C09.9, C10.0, C10.2-C10.4, C10.8-C10.9)
- Anterior Surface of Epiglottis (C10.1)
- Nasopharynx (C11.0-C11.3, C11.8-C11.9)
- Pyriform Sinus, Hypopharynx, Laryngopharynx (C12.9, C13.0-C13.2, C13.8-C13.9)
- Pharynx, NOS, and other Ill-Defined Oral Cavity Sites (C14.0, C14.2, C14.8)
- Surgery Codes
- Pharynx - (C09.0-C09.9, C10.0-C10.9, C11.0-C11.9, C12.9, C13.0-C13.9, C14.0)
- All Other Sites - (C14.2-C14.8)
Esophagus
- Coding Guidelines
- MP/H Coding Rules: see Other Sites
- CS Staging Scheme
- Esophagus (C15.0-C15.5, C15.8-C15.9)
- Surgery Codes
- Esophagus - (C15.0-C15.9)
Stomach
- MP/H Coding Rules: see Other Sites
- CS Staging Scheme
- Esophagus GE Junction
(C16.0-C16.3)
- Stomach (C16.1-C16.6, C16.8-C16.9)
- Esophagus GE Junction
- Surgery Codes
- Stomach - (C16.0-C16.9)
Small Intestine
- MP/H Coding Rules: see Other Sites
- CS Staging Scheme
- Small Intestine (C17.0-C17.3, C17.8-C17.9)
- Surgery Codes
- All Other Sites - (C17.0-C17.9)
Colon
- Coding Guidelines
- MP/H Coding Rules: Colon - (C18.0-C18.9)
- CS Staging Scheme
- Colon (C18.0-C18.9 Excluding Appendix (C18.1))
- Appendix (C18.1)
- Surgery Codes
- Colon - (C18.0-C18.9)
Rectosigmoid, Rectum
- Coding Guidelines
- MP/H Coding Rules: see Other Sites
- CS Staging Scheme
- Rectosigmoid, Rectum (C19.9, C20.9)
- Surgery Codes
- Rectosigmoid - (C19.9)
- Rectum - (C20.9)
Anus
- MP/H Coding Rules: see Other Sites
- CS Staging Scheme
- Surgery Codes
- Anus - (C210-C218)
Liver, Intrahepatic Bile Ducts
- MP/H Coding Rules: see Other Sites
- CS Staging Scheme
- Surgery Codes
- Liver and Intrahepatic Bile Ducts - (C22.0-C22.1)
Gallbladder, Extrahepatic Bile Ducts, Ampulla of Vater
- MP/H Coding Rules: see Other Sites
- CS Staging Schemas
- Gallbladder (C23.9)
- Extrahepatic Bile Duct(s) (C24.0)
- Ampulla of Vater (C24.1)
- Other Biliary and Biliary, NOS (C24.8-C24.9)
- Gallbladder (C23.9)
- Surgery Codes
- All Other Sites - (C23.9, C24.0-C24.9)
Pancreas
- MP/H Coding Rules: see Other Sites
- CS Staging Schemas
- Surgery Codes
- Pancreas - (C25.0-C25.9)
Other Digestive
- MP/H Coding Rules: see Other Sites
- CS Staging Scheme
- Surgery Codes
- All Other Sites - (C26.0-C26.9)
Nasal Cavity, Middle Ear
- MP/H Coding Rules: see Head and Neck (Oral Cavity)
- CS Staging Schemas
- Nasal Cavity (C30.0)
- Middle Ear (C30.1)
- Surgery Codes
- All Other Sites - (C30.0-C30.1)
Sinuses
- MP/H Coding Rules: see Head and Neck (Oral Cavity)
- CS Staging Schemas
- Maxillary Sinus (C31.0)
- Ethmoid Sinus (C31.1)
- Accessory (Paranasal) Sinus (C31.2-C31.3, C31.8-C31.9)
- Surgery Codes
- All Other Sites - (C31.0-C31.9)
Larynx
- MP/H Coding Rules: see Head and Neck (Oral Cavity)
- CS Staging Schemas
- Glottic Larynx (C32.0)
- Supraglottic Larynx (C32.1)
- Subglottic Larynx (C32.2)
- Larynx, Overlapping Lesion or Not Otherwise Specified (C32.3, C32.8-C32.9)
- Surgery Codes
- Larynx - (C32.0-C32.9)
Trachea
- MP/H Coding Rules: see Other Sites
- CS Staging Scheme
- Surgery Codes
- All Other Sites - (C33.9)
Lung
- Coding Guidelines
- MP/H Coding Rules: Lung - (C34.0-C34.9)
- CS Staging Scheme
- Surgery Codes
- Lung - (C34.0-C34.9)
Heart, Mediastinum, Pleura
- MP/H Coding Rules: see Other Sites
- CS Staging Schemas
- Surgery Codes
- All Other Sites - (C38.0-C38.8, C39.0-C39.9)
Bones, Joints, Cartilage
- Coding Guidelines
- MP/H Coding Rules: see Other Sites
- CS Staging Scheme
- Surgery Codes
Skin
- MP/H Coding Rules: see Other Sites
- CS Staging Schemas
- Skin (C44.0, C44.2-C44.9)
- Eyelid (C44.1)
- Surgery Codes
- Skin - (C44.0-C44.9)
Melanoma
- MP/H Coding Rules: Cutaneous Melanoma - (C44.0-C44.9)
- CS Staging Scheme
- Surgery Codes
- Skin - (C44.0-C44.9)
- All Other Sites - (C51.0-C51.9, C60.0-C60.9, C63.2)
Mycosis Fungoides, Sezary Disease
- MP/H Coding Rules: see Other Sites
- CS Staging Scheme
- Surgery Codes
- Skin - (C44.0-C44.9)
- All Other Sites - (C51.0-C51.9, C60.0-C60.9, C63.2)
Nerves, Nervous System, Soft Tissues
- Coding Guidelines: Bones, Joints, Cartilage
- MP/H Coding Rules: see Other Sites
- CS Staging Scheme
- Surgery Codes
Retroperitoneum, Peritoneum
- MP/H Coding Rules: see Other Sites
- CS Staging Scheme
- Retroperitoneum, Peritoneum (C48.0-C48.2, C48.8)
- Surgery Codes
- All Other Sites - (C48.0-C48.8)
Breast
- Coding Guidelines: Breast
- MP/H Coding Rules: Breast - (C50.0-C50.9)
- CS Staging Scheme
- Surgery Codes
- Breast (C50.0-C50.9)
Vulva, Vagina
- MP/H Coding Rules: see Other Sites
- CS Staging Schemes
- Vulva (C51.0-C51.2, C51.8-C51.9)
- Vagina (C52.9)
- Surgery Codes
- All Other Sites - (C51.0-C51.9, C52.9)
Cervix Uteri
- MP/H Coding Rules: see Other Sites
- CS Staging Scheme
- Surgery Codes
- Cervix Uteri - (C53.0-C53.9)
Corpus Uteri, Uterus, NOS
- MP/H Coding Rules: see Other Sites
- CS Staging Scheme
- Corpus Uteri; Uterus, NOS (C54.0-C54.3, C54.8-C54.9, C55.9)
- Surgery Codes
- Corpus Uteri - (C54.0-C55.9)
Ovary
- MP/H Coding Rules: see Other Sites
- CS Staging Scheme
- Surgery Codes
- Ovary - (C56.9)
Fallopian Tube, Ligaments, Adnexa
- MP/H Coding Rules: see Other Sites
- CS Staging Schemas
- Surgery Codes
- All Other Sites - (C57.0-C57.4)
Other and Unspecified Female Genital Organs, Placenta
- MP/H Coding Rules: see Other Sites
- CS Staging Schemas
- Surgery Codes
- All Other Sites - (C57.7-C57.9, C58.9)
Penis
- MP/H Coding Rules: see Other Sites
- CS Staging Scheme
- Penis (C60.0-C60.2, C60.8-C60.9)
- Surgery Codes
- All Other Sites - (C60.0-C60.9)
Prostate
- Coding Guidelines: Prostate
- MP/H Coding Rules: see Other Sites
- CS Staging Scheme
- Surgery Codes
- Prostate - (C61.9)
Testis
- MP/H Coding Rules: see Other Sites
- CS Staging Scheme
- Surgery Codes
- Testis - (C62.0-C62.9)
Other and Unspecified male Genital Organs
- MP/H Coding Rules: see Other Sites
- CS Staging Schemas
- Surgery Codes
- All Other Sites - (C63.0-C63.9)
Kidney
- Coding Guidelines: Kidney
- MP/H Coding Rules: Kidney - (C64.9)
- CS Staging Scheme
- Surgery Codes
- Kidney, Renal Pelvis, and Ureter - (C64.9, C65.9, C66.9)
Renal Pelvis, Ureter
- Coding Guidelines: Renal Pelvis and Ureter
- MP/H Coding Rules: Renal Pelvis, Ureter, Bladder and Other Urinary - (C65.9, C66.9, C67.0-C67.9, C68.0-C68.9)
- CS Staging Scheme
- Surgery Codes
- Kidney, Renal Pelvis, and Ureter - (C64.9, C65.9, C66.9)
Bladder
- Coding Guidelines: Bladder
- MP/H Coding Rules: see Renal Pelvis, Ureter, Bladder and Other Urinary
- CS Staging Scheme
- Surgery Codes
- Bladder - (C67.0-C67.9
Urethra, Other Urinary
- Coding Guidelines: Urethra
- MP/H Coding Rules: see Renal Pelvis, Ureter, Bladder and Other Urinary
- CS Staging Schemas
- Surgery Codes
- All Other Sites - (C68.0-C68.9)
Eye
- MP/H Coding Rules: see Other Sites
- CS Staging Schemas
- Conjunctiva (excludes retinoblastoma, malignant melanoma, Kaposi sarcoma and lymphoma) (C69.0)
- Malignant Melanoma of Conjunctiva (C69.0)
- Cornea, Retina, Choroid, Ciliary body (Iris, Lens, Sclera, Ureal Tract), Eyeball, Overlapping and Other Eye (excludes melanoma and retinoblastoma) (C69.1-C69.4, C69.8-C69.9)
- Malignant Melanoma of Iris (C69.4)
- Malignant Melanoma of Ciliary Body (C69.4)
- Malignant Melanoma of Choroid (C69.3)
- Malignant Melanoma of Other Eye (C69.1, C69.2, C69.5, C69.8-C69.9)
- Lacrimal Gland (C69.5)
- Lacrimal Sac (C69.5)
- Orbit (C69.6)
- Retinoblastoma (C69.0-C69.6, C69.8-C69.9)
- Ocular Adnexal Lymphoma (C44.1, C69.0, C69.5-C69.6)
- Conjunctiva (excludes retinoblastoma, malignant melanoma, Kaposi sarcoma and lymphoma) (C69.0)
- Surgery Codes
- All Other Sites - (C69.0-C69.9)
Brain, Central Nervous System, Malignant
- Coding Guidelines: Brain
- MP/H Coding Rules: Brain, Spinal Cord, Cranial Nerves, Pituitary Gland, Craniopharyngeal Duct and Pineal Gland - (C70.0, C70.1, C70.9, C71.0-C71.9, C72.0-C72.5, C72.8, C72.9, C75.1-C75.3)
- CS Staging Schemas
- Surgery Codes
- Brain - (C70.0-C70.9, C71.0-C71.9, C72.0-C72.9)
Brain, Central Nervous System, Benign and Borderline
- Coding Guidelines: Brain
- MP/H Coding Rules: Benign and Borderline Primary Intracranial and CNS Tumors - (C70.0, C70.1, C70.9, C71.0-C71.9, C72.0-C72.5, C72.8, C72.9, C75.1-C75.3)
- CS Staging Schemas
- Surgery Codes
- Brain - (C70.0-C70.9, C71.0-C71.9, C72.0-C72.9)
Thyroid
- Coding Guidelines: Thyroid Gland
- MP/H Coding Rules: see Other Sites
- CS Staging Scheme
- Surgery Codes
- Thyroid Gland - (C73.9)
Thymus, Adrenal and Other Endocrine Glands
- MP/H Coding Rules
- For Malignant Pituitary, Craniopharyngeal duct and Pineal Gland (C75.1-C75.3)
Multiple Primary Rules: See Malignant Meninges, Brain, Spinal Cord, Cranial Nerves, Pituitary gland, Craniopharyngeal duct and Pineal gland - For Benign, Borderline Pituitary, Craniopharyngeal duct and Pineal gland
Multiple Primary Rules: See Benign and Borderline Primary Intracranial and CNS Tumors - For Thymus, Adrenal gland, Carotid body, Aortic body and other paraganglia, Overlapping lesion of endocrine glands and related structures and Endocrine gland NOS (C37.9, C74.0-C74.1, C74.9, C75.4-C75.9)
See Other Sites
- For Malignant Pituitary, Craniopharyngeal duct and Pineal Gland (C75.1-C75.3)
- CS Staging Scheme
- Surgery Codes
- All Other Sites - (C37.9, C74.0-C74.9, C75.0-C75.9)
- MP/H Coding Rules
Kaposi Sarcoma
- Coding Guidelines: Kaposi Sarcoma of All Sites
- MP/H Coding Rules: see Other Sites
- CS Staging Scheme
- Surgery Codes
- See Site-specific Codes
Lymphoma
- Coding Guidelines: Lymph Nodes
- MP/H Coding Rules: See the Hematopoietic Database and Manual
- CS Staging Scheme
- Surgery Codes
- Lymph Nodes - (C77.0-C77.9)
- See site-specific codes
Hematopoietic, Reticuloendothelial, Immunoproliferative and Myeloproliferative
- MP/H Coding Rules: See the Hematopoietic Database and Manual
- CS Staging Scheme
- Hematopoietic, Reticuloendothelial, Immunoproliferative, and Myeloproliferative Neoplasms
(9731-9734, 9740-9742, 9750-9758, 9760-9762, 9764-9769, 9800-9801, 9805, 9820, 9823, 9826-9827, 9831-9837, 9840, 9860-9861, 9863, 9866-9867, 9870-9876, 9891, 9895-9897, 9910, 9920, 9930-9931, 9940, 9945-9946, 9948, 9950, 9960-9964, 9970, 9975, 9980, 9982-9987, 9989)
- Hematopoietic, Reticuloendothelial, Immunoproliferative, and Myeloproliferative Neoplasms
- Surgery Codes
- Hematopoietic/Reticuloendothelial/Immunoproliferative/Myeloproliferative Disease - (C42.0, C42.1, C42.3, C42.4)
Other and Unknown Sites
- MP/H Coding Rules: Other Sites
- CS Staging Scheme
- Other and Ill-Defined Sites, Unknown Primary Site (C42.0-C42.4, C76.0-C76.5, C76.7-C76.8, C77.0-C77.5, C77.8-C77.9, C80.9)
- C42 excludes hematopoietic, reticuloendothelial, immunoproliferative and myeloproliferative neoplasms, Hodgkin and non-Hodgkin lymphomas, and Kaposi sarcoma
- C77 excludes hematopoietic, reticuloendothelial, immunoproliferative and myeloproliferative neoplasms, Hodgkin and non-Hodgkin lymphomas, and Kaposi sarcoma
- Other and Ill-Defined Sites, Unknown Primary Site (C42.0-C42.4, C76.0-C76.5, C76.7-C76.8, C77.0-C77.5, C77.8-C77.9, C80.9)
- Surgery Codes
- See Hematopoietic, Reticuloendothelial, Immunoproliferative, and Myeloproliferative Disease - (C42.0, C42.1, C42.3, C42.4)
- Spleen - (C42.2)
- Unknown and Ill-Defined Primary Sites - (C76.0-C76.8, C80.9)
1 Part II of the Collaborative Stage Data Collection manual is included in this appendix. For an introduction to Collaborative Stage, see the general rules in Part I of the Collaborative Stage Data Collection Manual and Coding Instructions.
2 The surgery codes are based on the American College of Surgeons Commission on Cancer’s Facility Oncology Registry Data System, American College of Surgeons, Chicago, IL, 60611-321 (FORDS), Revised for 2012, Appendix B: Site-specific Surgery Codes. The surgery codes in this document are identical to the FORDS manual; only formatting and annotations may vary. The SEER Notes that appear in the Surgery Code sections contain information or instructions not found in FORDS or that are different from FORDS.