Research Papers
- Adaptive evolution and the birth of CTCF binding sites in the Drosophila genome
- CUX1 is a haploinsufficient tumor suppressor gene on chromosome 7 frequently inactivated in acute myeloid leukemia
- Robust and tunable circadian rhythms from differentially sensitive catalytic domains
- Integrated genomic analyses of ovarian carcinoma
- A cis-regulatory map of the Drosophila genome
- Chromatin occupancy analysis reveals genome-wide GATA factor switching during hematopoiesis
- A conserved eEF2 coding variant in SCA26 leads to loss of translational fidelity and increased susceptibility to proteostatic insult
- Orderly wheels of the cyanobacterial clock
- Caffeic acid phenethyl ester suppresses the proliferation of human prostate cancer cells through inhibition of p70S6K and Akt signaling networks
- Relating human genetic variation to variation in drug responses.
News
A Comprehensive Nuclear Receptor Network for Breast Cancer Cells
In breast cancer, nuclear receptors (NRs) play a prominent role in governing gene expression, have prognostic utility, and are therapeutic targets. We built a regulatory map for 24 NRs, six chromatin state markers, and 14 breast-cancer-associated transcription factors (TFs) that are expressed in the breast cancer cell line MCF-7.
The inner workings of the circadian clock
Center Investigator Michael Rust and colleagues reveals the biochemical mechanisms that allow the oscillations of the cyanobacterial biological clock to be tuned to changes in the environment while simultaneously maintaining a robust 24-hour period.
Argonne-Sponsored Meeting Showcases Scientific Advances in Soil Metagenomics
More than 140 researchers from the United States, Canada, Brazil, Asia (Taiwan), and Europe (Czech Republic, France, Germany, Spain) gathered at the Indian Lakes Resort near Chicago to participate in the 4th Annual Argonne Soil Metagenomics meeting October 3–5.
Systems Biology of Immune Cells at the Genomic Level
Aly Azeem Khan, IGSB/CBC Postdoctoral Fellow in the Institute for Genomics and Systems Biology, co-authored with collaborators at Genentech, Washington University, New York University, MD Anderson Cancer Center, and the Virginia Commonwealth University School of Medicine, a new study published online in advance of print in Science Magazine.
Why a diet rich in saturated fat can trigger bowel disorders
Dionysios Antonopoulos, an assistant biologist (microbiologist) in the Institute for Genomics and Systems Biology at Argonne National Laboratory, is co-author (with Suzanne Devkota, Bana Jabri, Eugene Chang, and others at the University of Chicago) of a new study on the role that diet plays in promoting complex immune disorders such as inflammatory bowel disease (IBD).
Aashish Jha was recently selected to receive a predoctoral fellowship from the University of Chicago
IGSB graduate student, Aashish Jha, in Kevin Whiteʼs lab, was recently selected to receive a predoctoral fellowship from the University of Chicagoʼs Center for Systems Biology of Oxygen Sensing. An Institutional Training Grant, “Training in O2 Biology in Health & Disease,” will support his research training. This award is based on Aashish Jhaʼs academic record, scientific performance in the lab, and relevance of his thesis project to the field of oxygen biology.
Seminars & Events
IGSB Seminar Series Alexander Stark, PhD
The University of Chicago
KCBD 1103
CCSB Science Jam 2013
KCBD 10160C
IGSB Seminar Series Lars Steinmetz, PhD
The University of Chicago
KCBD 1103
IGSB Seminar Series David Schwab, PhD
KCBD 1103
900 E. 57th Street
Chicago, IL 60637
IGSB Seminar Series Jay Shendure, MD, PhD
The University of Chicago KCBD 1103
