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Glossary of Terms

We know that many of the concepts used on this site can be difficult to understand. For that reason, we have provided you with a glossary to help you make sense of the terms used in Comparative Effectiveness Research. Every word that is defined in this glossary should appear highlighted throughout the Web site. When you come upon a highlighted term and would like to read the full definition, you can either click on the word to visit the glossary or roll your mouse over the word for a pop-up definition.

 

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Placebo Controlled Study

Definition: A study in which the effect of a drug is compared with the effect of a placebo (an inactive substance designed to resemble the drug). In placebo controlled clinical trials, participants receive either the drug being studied or a placebo. The results of the drug and placebo groups are then compared to see if the drug is more effective in treating the condition than the placebo is.

Example: For example, two placebo controlled studies have compared the drug risperidone with a placebo for treating behavioral problems in children having the diagnosis of autism. Both studies found that the children given risperidone had fewer behavioral problems than the children given a placebo.

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