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Measure Summary
Title
Acute myocardial infarction: percent of patients who are prescribed aspirin at hospital discharge.
Source(s)
Specifications manual for national hospital inpatient quality measures, version 4.1. Centers for Medicare & Medicaid Services (CMS), The Joint Commission; 2012 Jul. various p.
Jump ToGuideline ClassificationRelated Content

Measure Domain

Primary Measure Domain
Clinical Quality Measures: Process
Secondary Measure Domain
Does not apply to this measure

Brief Abstract

Description

This measure is used to assess the percent of acute myocardial infarction (AMI) patients, 18 years of age and older, who are prescribed aspirin at hospital discharge.

Rationale

Aspirin therapy in patients who have suffered an acute myocardial infarction (AMI) reduces the risk of adverse events and mortality. Studies have demonstrated that aspirin can reduce this risk by 20% (Antiplatelet Trialists' Collaboration, 1994). National guidelines strongly recommend long-term aspirin for the secondary prevention of subsequent cardiovascular events in eligible older patients discharged after AMI (Antman, 2004; Antman, 2008; Anderson, 2007; and Smith, 2006).

Evidence for Rationale
Anderson JL, Adams CD, Antman EM, Bridges CR, Califf RM, Casey DE Jr, Chavey WE 2nd, Fesmire FM, Hochman JS, Levin TN, Lincoff AM, Peterson ED, Theroux P, Wenger NK, Wright RS, Smith SC Jr, Jacobs AK, Adams CD, Anderson JL, Antman EM, Halperin JL, Hunt SA, Krumholz HM, Kushner FG, Lytle BW, Nishimura R, Ornato JP, Page RL, Riegel B, American College of Cardiology, American Heart Association Task Force on Practice Guidelines (Writing Committee, American College of Emergency Physicians, Society for Cardiovascular Angiography and Interventions, Society of Thoracic Surgeons, American Association of Cardiovascular and Pulmonary Rehabilitation, Society for Academic Emergency Medicine. ACC/AHA 2007 guidelines for the management of patients with unstable angina/non-ST-Elevation myocardial infarction: a report of the American College of Cardiology. J Am Coll Cardiol 2007 Aug 14;50(7):e1-157. [957 references] PubMed External Web Site Policy

Antman EM, Anbe DT, Armstrong PW, Bates ER, Green LA, Hand M, Hochman JS, Krumholz HM, Kushner FG, Lamas GA, Mullany CJ, Ornato JP, Pearle DL, Sloan MA, Smith SC Jr. ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction. A report of the Am Coll of Cardiol/Am Heart Assoc Task Force on Practice Guidelines (Committee to revise the 1999 guidelines). Bethesda (MD): American College of Cardiology (ACC), American Heart Association (AHA); 2004. 211 p. [1398 references]

Canadian Cardiovascular Society, American Academy of Family Physicians, American College of Cardiology, American Heart Association, Antman EM, Hand M, Armstrong PW, Bates ER, Green LA, Halasyamani LK, Hochman JS, Krumholz HM, Lamas GA, Mullany CJ, Pearle DL, Sloan MA, Smith SC Jr, Anbe DT, Kushner FG, Ornato JP, Pearle DL, Sloan MA, Jacobs AK, Adams CD, Anderson JL, Buller CE, Creager MA, Ettinger SM, Halperin JL, Hunt SA, Lytle BW, Nishimura R, Page RL, Riegel B, Tarkington LG, Yancy CW. 2007 focused update of the ACC/AHA 2004 guidelines for the management of patients with ST-elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 2008 Jan 15;51(2):210-47. [90 references] PubMed External Web Site Policy

Collaborative overview of randomised trials of antiplatelet therapy--I: Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients. Antiplatelet Trialists' Collaboration. BMJ 1994 Jan 8;308(6921):81-106. PubMed External Web Site Policy

Krumholz HM, Anderson JL, Bachelder BL, Fesmire FM, Fihn SD, Foody JM, Ho PM, Kosiborod MN, Masoudi FA, Nallamothu BK, American College of Cardiology/American Heart Association Task Force on Performance Measures, American Academy of Family Physicians, American College of Emergency Physicians, American Association of Cardiovascular and Pulmonary Rehabilitation, Society for Cardiovascular Angiography and Interventions, Society of Hospital Medicine. ACC/AHA 2008 performance measures for adults with ST-elevation and non-ST-elevation myocardial infarction [trunc]. J Am Coll Cardiol 2008 Dec 9;52(24):2046-99.

Smith SC Jr, Allen J, Blair SN, Bonow RO, Brass LM, Fonarow GC, Grundy SM, Hiratzka L, Jones D, Krumholz HM, Mosca L, Pasternak RC, Pearson T, Pfeffer MA, Taubert KA. AHA/ACC guidelines for secondary prevention for patients with coronary and other atherosclerotic vascular disease: 2006 update. Endorsed by the National Heart, Lung, and Blood Institute. J Am Coll Cardiol 2006 May 16;47(10):2130-9.
Primary Health Components

Acute myocardial infarction (AMI); aspirin

Denominator Description

Acute myocardial infarction (AMI) patients, 18 years of age and older (see the related "Denominator Inclusions/Exclusions" field)

Numerator Description

Acute myocardial infarction (AMI) patients who are prescribed aspirin at hospital discharge

Evidence Supporting the Measure

Type of Evidence Supporting the Criterion of Quality for the Measure
  • A clinical practice guideline or other peer-reviewed synthesis of the clinical research evidence
  • A systematic review of the clinical research literature (e.g., Cochrane Review)
  • One or more research studies published in a National Library of Medicine (NLM) indexed, peer-reviewed journal
Additional Information Supporting Need for the Measure

Each year, an estimated 785,000 Americans will have a new coronary event, and approximately 470,000 will have a recurrent event. An estimated additional 195,000 silent first myocardial infarctions occur each year. Approximately every 25 seconds, an American will have a coronary event, and approximately every minute, one will die. In 2004, acute myocardial infarction (AMI) resulted in 695,000 hospital stays and $31 billion in health expenditures. The risk of further cardiovascular complications, including recurrent MI, sudden cardiac death, heart failure, stroke, and angina pectoris, among AMI survivors is substantial.

Evidence for Additional Information Supporting Need for the Measure
Writing Group Members, Roger VL, Go AS, Lloyd-Jones DM, Benjamin EJ, Berry JD, Borden WB, Bravata DM, Dai S, Ford ES, Fox CS, Fullerton HJ, Gillespie C, Hailpern SM, Heit JA, Howard VJ, Kissela BM, Kittner SJ, Lackland DT, Lichtman JH, Lisabeth LD, Makuc DM, Marcus GM, Marelli A, Matchar DB, Moy CS, Mozaffarian D, Mussolino ME, Nichol G, Paynter NP, Soliman EZ, Sorlie PD, Sotoodehnia N, Turan TN, Virani SS, Wong ND, Woo D, Turner MB, on behalf of the American Heart Association Statistics Committee and Stroke, On behalf of the American Heart Association Statistics Committee and Stroke. Heart disease and stroke statistics--2012 update: a report from the American Heart Association. Circulation 2012 Jan 3;125(1):e2-e220. PubMed External Web Site Policy
Extent of Measure Testing

The core measure pilot project was a collaboration among The Joint Commission, five state hospital associations, five measurement systems, and 83 hospitals from across nine states. Participating hospitals collected and reported data for acute myocardial infarction (AMI) measures from December 2000 to December 2001.

Core measure reliability visits were completed in the summer of 2001 at a random sample of 16 participating hospitals across 6 states.

Preliminary data gathered during The Joint Commission's pilot project shows a mean measure rate of 95% for this measure.

This measure is reviewed bi-annually and revised as needed to ensure reliable specifications. An independent abstracting contractor is utilized by the Hospital Inpatient Quality Reporting Program to monitor validity of the measure specifications. Feedback from this contractor is incorporated into the proposed changes for each manual update.

Evidence for Extent of Measure Testing
Iowa Foundation for Medical Care, Hospital Inpatient Quality Reporting Program Support Contractor. Hospital Inpatient Quality Reporting Program data validation inclusion list. [internet]. Baltimore (MD): Centers for Medicare & Medicaid Services (CMS); [accessed 2012 Jul 31].

The Joint Commission. A comprehensive review of development and testing for national implementation of hospital core measures. Oakbrook Terrace (IL): The Joint Commission; 40 p.

State of Use of the Measure

State of Use
Current routine use
Current Use
Accreditation
Collaborative inter-organizational quality improvement
External oversight/Medicaid
External oversight/Medicare
Internal quality improvement
Pay-for-performance
Pay-for-reporting
Public reporting

Application of the Measure in its Current Use

Measurement Setting
Hospitals
Professionals Involved in Delivery of Health Services
Does not apply to this measure (e.g., measure is not provider specific)
Least Aggregated Level of Services Delivery Addressed
Single Health Care Delivery or Public Health Organizations
Statement of Acceptable Minimum Sample Size
Specified
Target Population Age

Age greater than or equal to 18 years

Target Population Gender
Either male or female

National Strategy for Quality Improvement in Health Care

National Quality Strategy Aim
Better Care
National Quality Strategy Priority
Prevention and Treatment of Leading Causes of Mortality

Institute of Medicine (IOM) National Health Care Quality Report Categories

IOM Care Need
Getting Better
Living with Illness
IOM Domain
Effectiveness

Data Collection for the Measure

Case Finding Period

Discharges January 1 through June 30 and July 1 through December 31

Denominator Sampling Frame
Patients associated with provider
Denominator (Index) Event or Characteristic
Clinical Condition
Institutionalization
Patient/Individual (Consumer) Characteristic
Denominator Time Window
Does not apply to this measure
Denominator Inclusions/Exclusions

Inclusions
Discharges, 18 years of age and older, with an International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) Principal Diagnosis Code for acute myocardial infarction (AMI) (as defined in the appendices of the original measure documentation)

Exclusions

  • Patients less than 18 years of age
  • Patients who have a Length of Stay (LOS) greater than 120 days
  • Patients with Comfort Measures Only (as defined in the Data Dictionary) documented
  • Patients enrolled in clinical trials
  • Patients discharged to another hospital
  • Patients who left against medical advice
  • Patients who expired
  • Patients discharged to home for hospice care
  • Patients discharged to a health care facility for hospice care
  • Patients with a documented Reason for No Aspirin at Discharge (as defined in the Data Dictionary)
Exclusions/Exceptions
Medical factors addressed
Patient factors addressed
Numerator Inclusions/Exclusions

Inclusions
Acute myocardial infarction (AMI) patients who are prescribed aspirin at hospital discharge

Exclusions
None

Numerator Search Strategy
Institutionalization
Data Source
Administrative clinical data
Paper medical record
Type of Health State
Does not apply to this measure
Instruments Used and/or Associated with the Measure

Unspecified

Computation of the Measure

Measure Specifies Disaggregation
Does not apply to this measure
Scoring
Rate/Proportion
Interpretation of Score
Desired value is a higher score
Allowance for Patient or Population Factors
Unspecified
Standard of Comparison
External comparison at a point in, or interval of, time
External comparison of time trends
Internal time comparison

Identifying Information

Original Title

AMI-2: aspirin prescribed at discharge.

Measure Set Name
Submitter
Centers for Medicare & Medicaid Services - Federal Government Agency [U.S.]
The Joint Commission - Health Care Accreditation Organization
Developer
Centers for Medicare & Medicaid Services/The Joint Commission
Funding Source(s)

All external funding for measure development has been received and used in full compliance with The Joint Commission's Corporate Sponsorship policies, which are available upon written request to The Joint Commission.

Centers for Medicare & Medicaid Services (CMS) funding is from the United States Government.

Composition of the Group that Developed the Measure

In February 1992, the Centers for Medicare & Medicaid Services (CMS) (formerly HCFA) and the American Medical Association convened a steering committee for the Cooperative Cardiovascular Project (CCP). The committee drafted measures heavily based on clinical practice guidelines developed by the American College of Cardiology (ACC) and the American Heart Association (AHA). More than 30 different physicians, health service researchers, and representatives of physician specialty societies or health care organizations participated in review and refinement of the measures. Acute myocardial infarction (AMI) study groups at Quality Improvement Organizations (formerly Peer Review Organizations) from the states of Alabama, Connecticut, Iowa, and Wisconsin also contributed. A subgroup of this committee, including members of the ACC who had participated in the development of guidelines on treatment of AMI, assisted in developing 26 potential quality-of-care indicators. These indicators were reviewed by other representatives of the ACC, the American College of Physicians, the American Academy of Family Physicians, and a panel of practicing physicians participating in the Internal Medicine Center to Advance Research and Education Practice Guidelines Review Network, and eleven measures were finalized and implemented, including this measure. The Joint Commission was also a co-developer of this measure as well. The original versions of this measure have undergone revisions over the years, and have evolved into the current version being operationalized in the Hospital Inpatient Quality Reporting Program today.

Financial Disclosures/Other Potential Conflicts of Interest

Expert panel members have made full disclosure of relevant financial and conflict of interest information in accordance with the Conflict of Interest policies, copies of which are available upon written request to The Joint Commission and the Centers for Medicare & Medicaid Services (CMS).

Endorser
National Quality Forum
Date of Endorsement

2012 Jan 18

Measure Initiative(s)
Hospital Compare
Hospital Inpatient Quality Reporting Program
Quality Check®
Adaptation

This measure was not adapted from another source.

Date of Most Current Version in NQMC
2012 Jul
Measure Maintenance

This measure is reviewed and updated by the developing organizations every 6 months.

Date of Next Anticipated Revision

Unspecified

Measure Status

This is the current release of the measure.

This measure updates a previous version: Specifications manual for national hospital quality measures, version 3.1a. Centers for Medicare & Medicaid Services (CMS), The Joint Commission; 2010 Apr 1. various p.

Source(s)
Specifications manual for national hospital inpatient quality measures, version 4.1. Centers for Medicare & Medicaid Services (CMS), The Joint Commission; 2012 Jul. various p.
Measure Availability

The individual measure, "AMI-2: Aspirin Prescribed at Discharge," is published in "Specifications Manual for National Hospital Inpatient Quality Measures." This document is available from The Joint Commission Web site External Web Site Policy. Information is also available from the QualityNet Web site External Web Site Policy. Check The Joint Commission Web site and QualityNet Web site regularly for the most recent version of the specifications manual and for the applicable dates of discharge.

Companion Documents

The following are available:

  • A software application designed for the collection and analysis of quality improvement data, the CMS Abstraction and Reporting Tool (CART), is available from the CMS CART Web site External Web Site Policy. Supporting documentation is also available. For more information, e-mail CMS PROINQUIRIES at proinquiries@cms.hhs.gov.
  • The Joint Commission. A comprehensive review of development and testing for national implementation of hospital core measures. Oakbrook Terrace (IL): The Joint Commission; 40 p. This document is available in Portable Document Format (PDF) from The Joint Commission Web site External Web Site Policy.
  • The Joint Commission. Attributes of core performance measures and associated evaluation criteria. Oakbrook Terrace (IL): The Joint Commission; 5 p. This document is available in PDF from The Joint Commission Web site External Web Site Policy.
  • Hospital compare: a quality tool provided by Medicare. [internet]. Washington (DC): U.S. Department of Health and Human Services; [accessed 2012 Jan 16]. This is available from the Medicare Web site. External Web Site Policy See the related QualityTools External Web Site Policy summary.
NQMC Status

This NQMC summary was originally completed by ECRI on February 7, 2003. This NQMC summary was updated by ECRI Institute on October 6, 2005, April 16, 2007, and October 26, 2007. The Joint Commission informed NQMC that this measure was updated on August 13, 2008 and provided an updated version of the NQMC summary. This NQMC summary was updated accordingly by ECRI Institute on November 11, 2008. The information was verified by the Centers for Medicare & Medicaid Services (CMS) on January 22, 2009. The Joint Commission informed NQMC that this measure was updated again on October 1, 2009 and provided an updated version of the NQMC summary. This NQMC summary was updated accordingly by ECRI Institute on November 25, 2009. The information was verified by CMS on February 18, 2010. This NQMC summary was updated again by ECRI Institute on October 8, 2010. The information was verified by The Joint Commission on December 3, 2010. The information was verified by CMS on January 6, 2011. This NQMC summary was retrofitted into the new template on May 13, 2011. The Joint Commission informed NQMC that this measure was updated again on March 28, 2012 and provided an updated version of the NQMC summary. This NQMC summary was updated accordingly by ECRI Institute on July 10, 2012. The information was verified by CMS on August 1, 2012.

Copyright Statement

The Specifications Manual for National Hospital Inpatient Quality Measures [Version 4.1, July, 2012] is the collaborative work of the Centers for Medicare & Medicaid Services and The Joint Commission. The Specifications Manual is periodically updated by the Centers for Medicare & Medicaid Services and The Joint Commission. Users of the Specifications Manual for National Hospital Inpatient Quality Measures should periodically verify that the most up-to-date version is being utilized.

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