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Measure Summary
Title
Appropriate treatment for children with upper respiratory infection (URI): percentage of children 3 months to 18 years of age who were given a diagnosis of upper respiratory infection (URI) and were not dispensed an antibiotic prescription.
Source(s)
National Committee for Quality Assurance (NCQA). HEDIS 2012: Healthcare Effectiveness Data and Information Set. Vol. 1, narrative. Washington (DC): National Committee for Quality Assurance (NCQA); 2011. various p.

National Committee for Quality Assurance (NCQA). HEDIS 2012: Healthcare Effectiveness Data and Information Set. Vol. 2, technical specifications for health plans. Washington (DC): National Committee for Quality Assurance (NCQA); 2011. various p.
Jump ToGuideline ClassificationRelated Content

Measure Domain

Primary Measure Domain
Clinical Quality Measures: Process
Secondary Measure Domain
Does not apply to this measure

Brief Abstract

Description

This measure is used to assess the percentage of children 3 months to 18 years of age who were given a diagnosis of upper respiratory infection (URI) and were not dispensed an antibiotic prescription on or three days after the Index Episode Start Date (IESD).

This measure is reported as an inverted rate [1 - (numerator/eligible population)]. A higher rate indicates appropriate treatment of children with URI (i.e., proportion for whom antibiotics were not prescribed).

Rationale

The common cold (or upper respiratory infection [URI]) is a frequent reason for children visiting the doctor's office. Though existing clinical guidelines do not support the use of antibiotics for the common cold, physicians often prescribe them for this ailment. Pediatric clinical practice guidelines do not recommend antibiotics for a majority of upper respiratory tract infections because of the viral etiology of these infections, including the common cold. A performance measure of antibiotic use for URI sheds light on the prevalence of inappropriate antibiotic prescribing in clinical practice and raises awareness of the importance of reducing inappropriate antibiotic use to combat antibiotic resistance in the community.

Evidence for Rationale
National Committee for Quality Assurance (NCQA). HEDIS 2012: Healthcare Effectiveness Data and Information Set. Vol. 1, narrative. Washington (DC): National Committee for Quality Assurance (NCQA); 2011. various p.

Rosenstein N, Phillips WR, Gerber MA, Marcy SM, Schwartz B, Dowell SF, et al. The common cold--principles of judicious use of antimicrobial agents. Pediatrics 1998;101(Suppl):181-4.
Primary Health Components

Upper respiratory infection (URI); antibiotic treatment; children

Denominator Description

Children 3 months as of July 1 of the year prior to the measurement year to 18 years as of June 30 of the measurement year, with a Negative Medication History and a Negative Competing Diagnosis, who had an outpatient or emergency department (ED) visit with only a diagnosis of upper respiratory infection (URI) during the Intake Period (see the related "Denominator Inclusions/Exclusions" field)

Numerator Description

Children from the denominator who were dispensed prescription for antibiotic medication (refer to Table CWP-C in the original measure documentation for a list of antibiotic medications) on or three days after the Index Episode Start Date (IESD) (see the related "Numerator Inclusions/Exclusions" field)

Evidence Supporting the Measure

Type of Evidence Supporting the Criterion of Quality for the Measure
  • A formal consensus procedure, involving experts in relevant clinical, methodological, public health and organizational sciences
  • One or more research studies published in a National Library of Medicine (NLM) indexed, peer-reviewed journal
Additional Information Supporting Need for the Measure
  • Upper respiratory infections (URIs) are self-regulating viral infections that cannot be treated by antibiotics. Despite this, clinical practice trends show that antibiotics are often prescribed, leading to a trend in overuse and growing antimicrobial resistance among patients.
  • Approximately over 100 million antibiotic prescriptions are written in the ambulatory care setting every year. According to the Centers for Disease Control and Prevention (CDC), antibiotics were prescribed during 68 percent of URI visits. Of these visits, 80 percent did not require the prescription of antibiotics as defined by practice guidelines.
  • In 2005, there were 1.17 billion visits to ambulatory clinics and emergency departments (EDs). 11 percent (130 million visits) were for acute respiratory infections.
  • In the United States, URIs are responsible for nearly $17 billion in direct costs (e.g., physician services and treatment because of complications) and $22.5 billion in indirect costs (e.g., absenteeism and lost productivity) every year.
  • Studies have shown that up to 60 percent of patients with colds or URIs seen in the ED are prescribed antibiotics, which have not demonstrated improvement in clinical outcomes.
  • Overuse of antibiotics is a significant issue in URI treatment. A survey conducted in 2004 illustrated that among children seen in a primary practice, outpatient or ED setting, those diagnosed with viral URIs experienced even higher rates of antibiotic prescription, even though antibiotics are ineffective for treating viral infections.
  • Antibiotic treatment is only infrequently appropriate for URIs. Misuse or overuse can be avoided by prescribing treatment when necessary, as well as educating patients and clinicians about the use of antibiotics in treating URIs.
Evidence for Additional Information Supporting Need for the Measure
Centers for Disease Control and Prevention (CDC). Get smart: know when antibiotics work. Facts about antibiotic resistance. [internet]. 2011 [accessed 2011 May 26].

Fendrick AM, Monto AS, Nightengale B, Sarnes M. The economic burden of non-influenza-related viral respiratory tract infection in the United States. Arch Intern Med 2003 Feb 24;163(4):487-94. PubMed External Web Site Policy

Friedman BC, Schwabe-Warf D, Goldman R. Reducing inappropriate antibiotic use among children with influenza infection. Can Fam Physician 2011 Jan;57(1):42-4. PubMed External Web Site Policy

Hart AM. An evidence-based approach to the diagnosis and management of acute respiratory infections. J Nurs Practitioners 2007;3(9):607-11.

Linder JA. Improving care for acute respiratory infections: better systems, not better microbiology. Clin Infect Dis 2007 Nov 1;45(9):1189-91. PubMed External Web Site Policy

National Committee for Quality Assurance (NCQA). The state of health care quality 2011. Continuous improvement and the expansion of quality measurement. Washington (DC): National Committee for Quality Assurance (NCQA); 2011. 199 p.

Ong S, Nakase J, Moran GJ, Karras DJ, Kuehnert MJ, Talan DA, EMERGEncy ID NET Study Group. Antibiotic use for emergency department patients with upper respiratory infections: prescribing practices, patient expectations, and patient satisfaction. Ann Emerg Med 2007 Sep;50(3):213-20. PubMed External Web Site Policy

Wong DM, Blumberg DA, Lowe LG. Guidelines for the use of antibiotics in acute upper respiratory tract infections. Am Fam Physician 2006 Sep 15;74(6):956-66. PubMed External Web Site Policy
Extent of Measure Testing

Unspecified

State of Use of the Measure

State of Use
Current routine use
Current Use
Accreditation
Decision-making by businesses about health plan purchasing
Decision-making by consumers about health plan/provider choice
External oversight/Medicaid
External oversight/State government program
Internal quality improvement
Pay-for-reporting
Public reporting

Application of the Measure in its Current Use

Measurement Setting
Managed Care Plans
Professionals Involved in Delivery of Health Services
Advanced Practice Nurses
Physician Assistants
Physicians
Least Aggregated Level of Services Delivery Addressed
Single Health Care Delivery or Public Health Organizations
Statement of Acceptable Minimum Sample Size
Unspecified
Target Population Age

Age 3 months to 18 years

Target Population Gender
Either male or female

National Strategy for Quality Improvement in Health Care

National Quality Strategy Aim
Better Care
National Quality Strategy Priority
Prevention and Treatment of Leading Causes of Mortality

Institute of Medicine (IOM) National Health Care Quality Report Categories

IOM Care Need
Getting Better
IOM Domain
Effectiveness

Data Collection for the Measure

Case Finding Period

A 12-month window that begins on July 1 of the year prior to the measurement year and ends on June 30 of the measurement year

Denominator Sampling Frame
Enrollees or beneficiaries
Denominator (Index) Event or Characteristic
Clinical Condition
Encounter
Patient/Individual (Consumer) Characteristic
Denominator Time Window
Time window brackets index event
Denominator Inclusions/Exclusions

Inclusions
Children 3 months as of July 1 of the year prior to the measurement year to 18 years as of June 30 of the measurement year, with a Negative Medication History and Negative Competing Diagnosis, who had an outpatient or emergency department (ED) visit with only a diagnosis of upper respiratory infection (URI) during the Intake Period

Note:

  • Children must have been continuously enrolled 30 days prior to the Episode Date through 3 days after the Episode Date (inclusive) with no gaps in enrollment during the continuous enrollment period.
  • Episode Date: The date of service for any outpatient or emergency department (ED) visit (refer to Table URI-B in the original measure documentation for codes to identify visit type) during the Intake Period with only a diagnosis of upper respiratory infection (URI) (refer to Table URI-A in the original measure documentation for codes to identify URI).
  • Negative Medication History: To qualify for Negative Medication History, the following criteria must be met.
    • A period of 30 days prior to the Episode Date, during which time the member had no pharmacy claims for either new or refill prescriptions for a listed antibiotic drug
    • No prescriptions filled more than 30 days prior to the Episode Date that are active on the Episode Date (refer to Table CWP-C in the original measure documentation for a list of antibiotic medications)
  • A prescription is considered active if the "days supply" indicated on the date when the member filled the prescription is the number of days or more between that date and the relevant service date. The 30-day look back period for pharmacy data includes the 30 days prior to the Intake Period.
  • Negative Competing Diagnosis: The Episode Date and three days following the Episode Date, when the member had no claims/encounters with any competing diagnosis (refer to Table URI-C in the original measure documentation for codes to identify competing diagnoses).
  • Intake Period: A 12-month window that begins on July 1 of the year prior to the measurement year and ends on June 30 of the measurement year. The Intake Period captures eligible episodes of treatment.

Refer to the original measure documentation for steps to identify the eligible population.

Exclusions

  • Exclude claims/encounters with more than one diagnosis.
  • Do not include ED visits that result in an inpatient admission.
  • Test for Negative Medication History. Exclude Episode Dates where a new or refill prescription for an antibiotic medication was filled 30 days prior to the Episode Date or was active on the Episode Date (refer to Table CWP-C in the original measure documentation for a list of antibiotic medications).
  • Test for Negative Competing Diagnosis. Exclude Episode Dates where the member had a claim/encounter with a competing diagnosis (refer to Table URI-C in the original measure documentation for codes to identify competing diagnosis) on or 3 days after the Episode Date.
Exclusions/Exceptions
Unspecified
Numerator Inclusions/Exclusions

Inclusions
Children from the denominator who were dispensed prescription for antibiotic medication (refer to Table CWP-C in the original measure documentation for a list of antibiotic medications) on or three days after the Index Episode Start Date (IESD)*

Note: This measure is reported as an inverted rate [1 - (numerator/eligible population)]. A higher rate indicates appropriate treatment of children with URI (i.e., proportion for whom antibiotics were not prescribed).

*IESD: The earliest Episode Date during the Intake Period that meets all of the following criteria:

  • A 30-day Negative Medication History prior to the Episode Date
  • A Negative Competing Diagnosis during the 3 days after the Episode Date
  • The member was continuously enrolled 30 days prior to the Episode Date through 3 days after the Episode Date

Exclusions
Unspecified

Numerator Search Strategy
Fixed time period or point in time
Data Source
Administrative clinical data
Pharmacy data
Type of Health State
Does not apply to this measure
Instruments Used and/or Associated with the Measure

Unspecified

Computation of the Measure

Measure Specifies Disaggregation
Does not apply to this measure
Scoring
Rate/Proportion
Interpretation of Score
Desired value is a higher score
Allowance for Patient or Population Factors
Analysis by subgroup (stratification by individual factors, geographic factors, etc.)
Description of Allowance for Patient or Population Factors

This measure requires that separate rates be reported for Medicaid and commercial product lines.

Standard of Comparison
External comparison at a point in, or interval of, time
External comparison of time trends
Internal time comparison

Identifying Information

Original Title

Appropriate treatment for children with upper respiratory infection (URI).

Measure Set Name
Measure Subset Name
Submitter
National Committee for Quality Assurance - Health Care Accreditation Organization
Developer
National Committee for Quality Assurance - Health Care Accreditation Organization
Funding Source(s)

Unspecified

Composition of the Group that Developed the Measure

National Committee for Quality Assurance's (NCQA's) Measurement Advisory Panels (MAPs) are composed of clinical and research experts with an understanding of quality performance measurement in the particular clinical content areas.

Financial Disclosures/Other Potential Conflicts of Interest

In order to fulfill National Committee for Quality Assurance's (NCQA's) mission and vision of improving health care quality through measurement, transparency and accountability, all participants in NCQA's expert panels are required to disclose potential conflicts of interest prior to their participation. The goal of this Conflict Policy is to ensure that decisions which impact development of NCQA's products and services are made as objectively as possible, without improper bias or influence.

Endorser
National Quality Forum
Date of Endorsement

2009 Aug 10

Measure Initiative(s)
Ambulatory Care Quality Alliance (AQA)
Physician Quality Reporting System
Adaptation

This measure was not adapted from another source.

Date of Most Current Version in NQMC
2011 Jul
Measure Maintenance

Unspecified

Date of Next Anticipated Revision

Unspecified

Measure Status

Please note: This measure has been updated. The National Quality Measures Clearinghouse is working to update this summary.

Source(s)
National Committee for Quality Assurance (NCQA). HEDIS 2012: Healthcare Effectiveness Data and Information Set. Vol. 1, narrative. Washington (DC): National Committee for Quality Assurance (NCQA); 2011. various p.

National Committee for Quality Assurance (NCQA). HEDIS 2012: Healthcare Effectiveness Data and Information Set. Vol. 2, technical specifications for health plans. Washington (DC): National Committee for Quality Assurance (NCQA); 2011. various p.
Measure Availability

The individual measure, "Appropriate Treatment for Children with Upper Respiratory Infection (URI)," is published in "HEDIS® 2012. Healthcare Effectiveness Data & Information Set. Vol. 2, Technical Specifications for Health Plans."

For more information, contact the National Committee for Quality Assurance (NCQA) at 1100 13th Street, NW, Suite 1000, Washington, DC 20005; Telephone: 202-955-3500; Fax: 202-955-3599; Web site: www.ncqa.org External Web Site Policy.

Companion Documents

The following is available:

  • National Committee for Quality Assurance (NCQA). The state of health care quality 2011. Continuous improvement and the expansion of quality measurement. Washington (DC): National Committee for Quality Assurance (NCQA); 2011. 199 p.

For more information, contact the National Committee for Quality Assurance (NCQA) at 1100 13th Street, NW, Suite 1000, Washington, DC 20005; Telephone: 202-955-3500; Fax: 202-955-3599; Web site: www.ncqa.org External Web Site Policy.

NQMC Status

This NQMC summary was completed by ECRI on April 11, 2005. The information was verified by the measure developer on December 15, 2005. This NQMC summary was updated by ECRI Institute on November 15, 2007. The information was not verified by the measure developer. This NQMC summary was updated by ECRI Institute on March 10, 2009. The information was verified by the measure developer on May 29, 2009. This NQMC summary was updated again by ECRI Institute on January 15, 2010 and February 16, 2011. This NQMC summary was retrofitted into the new template on June 30, 2011. This NQMC summary was updated again by ECRI Institute on May 16, 2012.

Copyright Statement

This NQMC summary is based on the original measure, which is subject to the measure developer's copyright restrictions.

For detailed specifications regarding the National Committee on Quality Assurance (NCQA) measures, refer to HEDIS Volume 2: Technical Specifications for Health Plans, available from the NCQA Web site at www.ncqa.org External Web Site Policy.

Disclaimer

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