This concise document outlines the basics of Item Unique Identification (IUID), including such topic areas as: Regulatory Environment, Item Unique Identification Program, Policy and Regulations, the IUID Life Cycle, What Items To Unique Identify, Item Unique Identification Mark, 2D Data Matrix, IUID Equivalents, Encoding the UII Data, Issuing Agency Codes for Use in Item Unique Identification, Reader Technology, Accounting and Valuation of Items, Data Submission, and the IUID Registry, among others.