14:10 EST (02:10 PM EST)
CDCHAN-00170-03-12-17-ADV-N
Severe Acute Respiratory Syndrome (SARS) in Taiwan
On December 17, 2003, the Taiwanese Department of Health reported a single case of infection with SARS-associated coronavirus (SARS-CoV) in a research scientist in Taiwan. The press release from the Taiwanese Department of Health is provided below and is also available on that agency's website at http://sars.doh.gov.tw/news/2003121701.html. Additional information about the report is available on the website of the World Health Organization (WHO) http://www.who.int/csr/don/2003_12_17/en/.
CDC is in close communication with the Department of Health in Taiwan and with WHO regarding this report. This is the second case of SARS-CoV infection that was likely acquired in a laboratory setting since the initial worldwide outbreak, and it reinforces the need for careful adherence to recommended laboratory safety practices for SARS-CoV. Recommendations for these laboratory protocols are available in Supplement F, Appendix F 4, "Laboratory Biosafety Guidelines for Handling and Processing Specimens Associated with SARS, in CDC's draft Public Health Guidance for Community-Level Preparedness and Response to Severe Acute Respiratory Syndrome (SARS) http://www.cdc.gov/ncidod/sars/sarsprepplan.htm.
Since this appears to be a laboratory-acquired infection with no evidence of secondary transmission reported to date, the guidelines and recommendations for SARS surveillance, evaluation, and reporting in the absence of SARS-CoV transmission still apply. For more information, see the CDC document, "In the Absence of SARS-CoV Transmission Worldwide: Guidance for Surveillance, Clinical and Laboratory Evaluation, and Reporting" http://www.cdc.gov/ncidod/sars/absenceofsars.htm.
Additional information will be reported as more is learned about the situation.
______________________________________________
Confirmed SARS case in research laboratory in Taiwan December 17, 2003
A 44 year-old male researcher was
confirmed to have SARS on December 17, 2003
in Taiwan. A senior scientist in the Institute of Preventive Medicine, National Defense University in Taipei, sponsored by the National Science
Council, has been working on a SARS study in Taiwan's only P4 laboratory since June. His work laboratory is
suspected as the source of infection, which is undergoing further
investigation.
After developing a fever on December 10, the researcher stayed home to rest and
recuperate. The patient noted initial symptoms and signs were similar to the
flu until he developed diarrhea. He then visited the Tri-Service General Hospital on the evening on December 16, at
which time a chest X-ray revealed pneumonia in his right lung. SARS was
immediately suspected, thus throat swab, gargling fluid, and blood samples were
obtained to conduct a real-time PCR and RT-PCR tests for the SARS coronavirus.
The tests in the Tri-Service General Hospital came back as SARS-positive. In the
early morning of December 17, which was six hours later, the case was further
confirmed by the virology laboratory of Taiwan's Center for Disease Control.
This SARS infection is the second SARS-CoV infection of a research person
working on SARS research since the Singapore case this last September. Why infection in a P4 laboratory occurred is
currently being investigated. Contact tracing was immediately performed, while
environmental sampling from the P4 laboratory is now underway.
So far, no fever has been detected in the researcher's colleagues or family
members, who are now undergoing a 14-day self-initiated health check program.
Close contacts will be put under home quarantine if fever should develop in
these persons.
The control level for SARS precaution has been raised from level zero to the
more stringent level B by the special SARS committee as of 12:00 AM on December 18, 2003.
Taiwan CDC had already initiated fever monitoring as scheduled in government
institutions and schools in Taiwan as of
December 15 as part of its efforts to prevent the reemergence of SARS and the
flu. This measure will become mandatory after this laboratory infection
episode. Travelers with fever will be restricted from leaving Taiwan and will be required to obtain a
health certificate from a hospital. Taiwan CDC has ordered all the laboratories
which work on SARS-CoV culture to undergo stringent disinfection procedures and
all research on viral cultures will be suspended until biosafety has been
guaranteed and approved by the government. The SARS control level will return
to level zero if no new cases are detected in the following 21 days. No
community or hospital SARS infections have been identified in Taiwan since July 5.
SOURCE: Department of Health, Taiwan: http://sars.doh.gov.tw/news/2003121701.html
HAN Message Types
- Health Alert: Conveys the highest level of importance; warrants immediate action or attention. Example: HAN00001
- Health Advisory: Provides important information for a specific incident or situation; may not require immediate action. Example: HAN00316
- Health Update: Provides updated information regarding an incident or situation; unlikely to require immediate action. Example: HAN00309
- Info Service: Provides general information that is not necessarily considered to be of an emergent nature. Example: HAN00319
## This Message was distributed to State and Local Health Officers, Public Information Officers, Epidemiologists and HAN Coordinators as well as Clinician organizations ##
You have received this message based upon the information contained within our emergency notification database. If you have a different or additional e-mail or fax address that you would like us to use, please contact your State-based Health Alert Network program at your State or local health department.
- Content source: CDC Emergency Risk Communication Branch (ERCB), Division of Emergency Operations (DEO), Office of Public Health Preparedness and Response (OPHPR)
Get email updates
To receive email updates about this page, enter your email address:
Contact Us:
- Centers for Disease Control and Prevention
1600 Clifton Rd
Atlanta, GA 30333 - 800-CDC-INFO
(800-232-4636)
TTY: (888) 232-6348 - Contact CDC-INFO