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Move LeftMove Right
- Research
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- Children's Health
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- Diabetes & Obesity
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Diabetes and obesity
Researchers in the
Diabetes and Obesity Center,
located in Lake Nona, Orlando, are investigating
the pathophysiology of common
metabolic diseases (such as obesity) and the
cardiovascular complications they cause.
This multi-disciplinary group studies the
control of metabolism, including the complex
interactions between cells and organs that
influence caloric intake and energy balance.
- Infectious & Inflammatory Diseases
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Infection and inflammation
Researchers in the
Infectious and
Inflammatory Disease Center study the relationship between the human body and the bacteria that live within it.
They take a
system-wide appreciation of what’s
happening in a cell or organism and develop the computing and organizational power to make sense of it all.
- Neuroscience, Aging & Stem Cell Research
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Neuroscience and aging
Neuroscience may be the yin to cancer’s yang. If we can learn how to kill treatment-resistant cancer cells, we can learn how to protect cells in the brain. Neurodegenerative diseases, such as Alzheimer's, and cancer, are both diseases of aging. Scientists at Sanford-Burnham are advancing the understanding of degenerative diseases, as well as the processes of normal aging.
Improving human health
Discoveries made by scientists in the Center have paved the way for development of a
drug for Alzheimer's that, for the first time, gets to the root of the problem, possibly preventing brain cell death rather than merely masking symptoms caused by loss of these cells. Numerous other strategies are being developed for either protecting cells or replacing cells lost due to
degenerative diseases
of the brain and other organs.
Read More
- Translational Research
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From the lab bench
The
Translational Research Institute for Metabolism and Diabetes
serves as a bridge between basic discovery research and patient-oriented research.
It binds the strengths of Florida Hospital’s large patient base and
clinical research expertise with Sanford-Burnham’s basic science and
advanced research technologies in metabolomics, genomics and proteomics.
To the bedside
The TRI is expected to hasten the discovery and development of new approaches to diagnose, prevent, and treat
diabetes,
obesity and their cardiovascular complications. One key aim is to produce unique insights into the sub-classifications of diabetes, thus promoting the advent of
personalized disease therapies. Read More
- Stem Cells
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Stem cell research
Seven integrated core divisions comprise the
Stem Cell Research Center, each with its own
mission to advance stem cell discoveries.
One division specializes in growing stem cells
for study. Another focuses on developing new
imaging technology. In another, scientists are
producing the world's largest bank of
embryonic-like stem cells generated from human
patients with a range of diseases.
Stem cell promise
Stem cells are distinguished by their ability to
differentiate into many types of cells in the
body and to self-replicate indefinitely. Their
very nature has intrigued scientists who foresee
a day when stem cells could be used to
replace
diseased and injured tissue in patients, to
screen and test new drugs, and to learn more
about our fundamental biology.
Read More
- Shared Resources
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Shared resources
The Institute provides scientists with access to state-of-the-art instrumentation through a network of
over 30 technology cores. This infrastructure supports scientists with advanced technologies that otherwise would be impossible for one lab to afford.
Shared Resources also offers investigators the expertise to help design and interpret their experiments and if desired, train their lab staff to self-operate the advanced equipment.
- Nanomedicine
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Turning an innovation...
The Office of Technology Management and Commercialization
helps bring biomedical research innovations to the marketplace as new therapies. Our business development team is also actively engaged in developing relationships with potential partners and funding organizations for the advancement of shared research initiatives.
…into a life-saving product
Since the Institute’s founding in 1976, our research has led to more than 600 patents and 90 license agreements with strategic partners. We are proud to partner with
Ortho-McNeil-Janssen Pharmaceuticals, Inc. (a division of Johnson & Johnson),
Pfizer, and
Takeda to advance our discoveries to the clinical research stage more quickly.
Read More
- Chemical Genomics
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Chemical genomics
Where do new medicines come from? Sanford-Burnham is part of
an NIH effort to bridge the gap between basic research carried out in academic research laboratories and FDA approval of new medicines. The
Conrad Prebys Center for Chemical Genomics (CPCCG) at Sanford-Burnham screens chemical compounds by the millions to find the few that could potentially be developed into new medicines.
- Cancer
- Children's Health
- Diabetes & Obesity
- Infectious &
Inflammatory Diseases
- Neuroscience, Aging
& Stem Cell Research
- Chemical Genomics
& Drug Discovery
- Commercialization
- Shared Resources
- Stem Cells
- Translational Research
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