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Occupational Disease and Nanoparticles

Categories: Nanotechnology

NIOSH research has shown that some nanoparticles, including certain types of carbon nanotubes and metal oxides, can be toxic to the heart and lung in mice and rats in laboratory experiments. Other research has demonstrated various other adverse effects of nanoparticles. Through its Approaches to Safe Nanotechnology, NIOSH recommends that specific precautions be taken to protect workers who might be exposed to any level of nanoparticles or nanoparticle-containing materials. A big question left unanswered is, can nanoparticles cause the same types of disease in humans?

Nanotechnology: Human and Environmental Exposure Assessment of Nanomaterials Workshop

Categories: Nanotechnology

nano workshop logoDetermining whether a material or substance poses an occupational health risk depends on knowing not only the potential toxic characteristics of the material, but also the characteristics of exposure. To what concentrations are workers exposed, for how long, and in what ways? In research to answer the question of whether nanomaterials pose work-related health risks, exposure assessment is particularly vital. Because of the relative newness of nanotechnology, very little exposure data have been reported in the scientific literature. At this stage, measuring or determining risk becomes a little like trying to solve a mystery when major clues are missing. Scientists and engineers face this challenge even as the market for nanotechnology grows, and along with it, an increasing demand from diverse parties for guidance to underpin its responsible development.

Persistent Pulmonary Fibrosis, Migration to the Pleura, and Other Preliminary New Findings after Subchronic Exposure to Multi-Walled Carbon Nanotubes

Categories: Nanotechnology

Multi-walled carbon nanotubes, known as MWCNTs for short, are a type of engineered nanomaterial that shows promise for various applications. These include the potential for creating stronger, more durable building materials; improving cancer therapies; creating more efficient means of energy generation, storage, and transmission; and speeding computer processes. However, as with other types of engineered nanomaterials, the potential occupational health implications of MWNCTs are not well understood at this emergent stage of the technology. A broad group of health and safety practitioners and business observers have agreed that research is vital for determining if MWCNTs pose a health risk for workers engaged in their production and industrial use, and for informing the responsible development of this technology. There is general agreement that this issue must be approached in a proactive manner with good research in order for society to benefit from the many promises this new class of materials has to offer.

Nanotechnology: Should carbon nanotubes be handled in the workplace like asbestos?

Categories: Nanotechnology

Multi-walled carbon nanotubes in conducting airways of the mouse lung after inhalation exposure

Multi-walled carbon nanotubes in conducting airways of the mouse lung after inhalation exposure. By Robert Mercer

Nanotechnology poses a question for occupational health and safety professionals. Does this technology, and the tiny nanoparticles that are its tools, pose an unintended risk of illness or injury for workers employed in the industry?

The National Institute for Occupational Safety and Health is at the forefront of the effort to understand the health and safety ramifications of working with nanomaterials. There have been an increasing number of scientific publications from the research community at large—including a new study issued just this week—that address one type of nanomaterial in particular, carbon nanotubes, and seek to determine if they biologically behave like asbestos. That is, if inhaled, are carbon nanotubes likely to cause irreparable and fatal effects such as those associated with asbestos exposure? The effects of asbestos include severe lung fibrosis or scarring, lung cancer, including cancer of the lining of the lungs or pleura called mesothelioma.

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