Advancing the Next Generation (NexGen) of Risk Assessment
The landscape of risk assessment is changing with new advances in molecular biology, the advent of several recent and important reports from the National Research Council 
, and volumes of new test data emerging from the Tox21 and European REACH programs.
The Environmental Protection Agency (EPA) is embarking on an exploration of the new science and methods that are ripe for incorporation into currently emerging and future risk assessments. This program—Advancing the Next Generation of Risk Assessment (NexGen)—is a collaborative effort among EPA's Computational Toxicology Program ; National Institutes of Environmental Health Sciences / National Toxicology Program; Centers for Disease Control / Agency for Toxic Substances and Disease Registry; National Human Genome Research Institute; and the State of California’s Environmental Protection Agency.
NexGen is a component of a high priority research program entitled Chemical Safety for Sustainability (CSS) http://www.epa.gov/ord/priorities/docs/CSSFrameworkMarch2011WorkingDocument.pdf (33pp, 1.28MB) and is focused on the fostering practical applications on new methods in risk assessment. Thus, NexGen provides a link from CSS to Human Health Risk Assessment.
Key Objectives
NexGen: The Future of Chemical Risk Assessment
Federal and state agencies are collaborating to make chemical risk assessment more responsive and efficient.
NexGen: Informed Decisions for Healthier Lives
These more effective and efficient chemical risk assessments will help you make more informed decisions and lead a healthier life.
NexGen: A New Road for Chemical Risk Assessment
You can help create a new roadmap for a more solution-oriented, efficient, and effective chemical risk assessment process.
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Recent Additions
- 12/11: Workshop proceedings from the Individual Exposomes workshop
- 4/11: The most recent Emerging Science newsletter is now available for download: Predicting Later-Life Health Outcomes of Early-life Exposures (PDF)
- 2/11: The 2011 NexGen Public Dialogue Conference presentation videos, slides, and draft summary report are on-line.